Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mei-chun Gao, Qin-chi Lu, Yan-sheng Li, Jia-lin She. Study on hippocampal volume with quantitative 3T magnetic resonance imaging in Chinese patients with epilepsy. Chinese medical journal. vol 125. issue 18. 2013-02-13. PMID:22964312. |
this study aimed to study the hippocampal volumes (hvs) with quantitative mri measurement in chinese patients with epilepsy. |
2013-02-13 |
2023-08-12 |
Not clear |
Kázmér Karádi, József Janszky, Csilla Gyimesi, Zsolt Horváth, Tivadar Lucza, Tamás Dóczi, János Kállai, Hajnalka Abrahá. Correlation between calbindin expression in granule cells of the resected hippocampal dentate gyrus and verbal memory in temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 25. issue 1. 2013-02-12. PMID:22796338. |
in addition, we found significant linear regression between calbindin expression and short-term and long-term percent retention of avlt in patients whose epilepsy was caused by malformation of cortical development or tumor and when no hippocampal sclerosis and substantial neuronal loss were detected. |
2013-02-12 |
2023-08-12 |
mouse |
José Pimentel, Ana Rita Peralta, Alexandre Campos, Carla Bentes, António G Ferreir. Antiepileptic drugs management and long-term seizure outcome in post surgical mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsy research. vol 100. issue 1-2. 2013-02-08. PMID:22336897. |
we evaluated the aeds management's role in the outcome of post surgical epilepsy patients with hippocampal sclerosis (hs). |
2013-02-08 |
2023-08-12 |
Not clear |
Alan W C Yuen, Josemir W Sande. Can magnesium supplementation reduce seizures in people with epilepsy? A hypothesis. Epilepsy research. vol 100. issue 1-2. 2013-02-08. PMID:22406257. |
magnesium deficiency decreases seizure thresholds in animal models of epilepsy and indeed low magnesium concentration in the perfusate is a common method of generating spontaneous epileptiform discharges from rat hippocampal slices. |
2013-02-08 |
2023-08-12 |
rat |
Gianluca Isoardo, Isabella Morra, Giulia Chiarle, Valentina Audrito, Silvia Deaglio, Antonio Melcarne, Carola Junemann, Michele Naddeo, Maurizio Cogoni, Maria Consuelo Valentini, Andrea Limberti, Federico Faccani, Fabio Malavasi, Giuliano Faccan. Different aquaporin-4 expression in glioblastoma multiforme patients with and without seizures. Molecular medicine (Cambridge, Mass.). vol 18. 2013-02-06. PMID:22714714. |
dysregulation of aqp-4 also occurs in hippocampal sclerosis and cortical dysplasia in patients with refractory partial epilepsy. |
2013-02-06 |
2023-08-12 |
Not clear |
Seung-Tae Kim, Ah-Reum Doo, Seung-Nam Kim, Song-Yi Kim, Yoon Young Kim, Jang-Hyun Kim, Hyejung Lee, Chang Shik Yin, Hi-Joon Par. Acupuncture suppresses kainic acid-induced neuronal death and inflammatory events in mouse hippocampus. The journal of physiological sciences : JPS. vol 62. issue 5. 2013-01-18. PMID:22773088. |
the present study investigated a possible role of acupuncture in reducing hippocampal cell death and inflammatory events, using a mouse model of kainic acid-induced epilepsy. |
2013-01-18 |
2023-08-12 |
mouse |
Seung-Tae Kim, Ah-Reum Doo, Seung-Nam Kim, Song-Yi Kim, Yoon Young Kim, Jang-Hyun Kim, Hyejung Lee, Chang Shik Yin, Hi-Joon Par. Acupuncture suppresses kainic acid-induced neuronal death and inflammatory events in mouse hippocampus. The journal of physiological sciences : JPS. vol 62. issue 5. 2013-01-18. PMID:22773088. |
these results indicate that acupuncture at ht8 can inhibit hippocampal cell death and suppress ka-induced inflammatory events, suggesting a possible role for acupuncture in the treatment of epilepsy. |
2013-01-18 |
2023-08-12 |
mouse |
Tobias Engel, Alba Jimenez-Pacheco, Maria Teresa Miras-Portugal, Miguel Diaz-Hernandez, David C Henshal. P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. International journal of physiology, pathophysiology and pharmacology. vol 4. issue 4. 2013-01-16. PMID:23320131. |
p2x7 receptor expression is also increased in the hippocampus in experimental epilepsy. |
2013-01-16 |
2023-08-12 |
mouse |
Joan Y W Liu, Maria Thom, Claudia B Catarino, Lillian Martinian, Dominique Figarella-Branger, Fabrice Bartolomei, Matthias Koepp, Sanjay M Sisodiy. Neuropathology of the blood-brain barrier and pharmaco-resistance in human epilepsy. Brain : a journal of neurology. vol 135. issue Pt 10. 2013-01-15. PMID:22750659. |
in this valuable set of resources, we found that: (i) there is a highly localized overexpression of p-glycoprotein in the epileptogenic hippocampus of patients with drug-resistant epilepsy; (ii) this overexpression appears specific to p-glycoprotein and does not affect other transporters; (iii) p-glycoprotein is expressed on the vascular endothelium and end-feet of vascular glia (forming a 'double cuff') in drug-resistant epileptic cases but not in post-mortem controls or surgical epilepsy tissue with electrode-related injuries; (iv) an acute insult from intracranial electrode recording causes localized inflammation, increased blood-brain barrier permeability and structural changes to vasculature detectable for up to at least 330 days and (v) chronic epilepsy is associated with inflammation, enhanced blood-brain barrier permeability and increased p-glycoprotein expression. |
2013-01-15 |
2023-08-12 |
human |
Richard Kovács, Uwe Heinemann, Christian Steinhäuse. Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: role of astroglia. Epilepsia. vol 53 Suppl 6. 2013-01-15. PMID:23134496. |
the expression of astrocytic gap junctional proteins connexin 43 (cx43) and connexin 30 (cx30) is altered in epilepsy, and changes in gap junctional communication were found in sclerotic hippocampal tissue in animal models of epilepsy. |
2013-01-15 |
2023-08-12 |
Not clear |
Giovanni Carriero, Salvatore Arcieri, Alessandro Cattalini, Laura Corsi, Vadym Gnatkovsky, Marco de Curti. A guinea pig model of mesial temporal lobe epilepsy following nonconvulsive status epilepticus induced by unilateral intrahippocampal injection of kainic acid. Epilepsia. vol 53. issue 11. 2013-01-11. PMID:22998690. |
we describe herein a focal epilepsy model of mesial temporal (hippocampal) origin that relies on the analysis of interictal and ictal electroencephalography (eeg) patterns and on their correlation with seizure symptoms and neuropathologic findings. |
2013-01-11 |
2023-08-12 |
human |
Guo-feng Wu, Shi-hai Shan, You-zhong Don. [Effect of flunarizine on the epileptiform discharges in cortex and hippocampus of rat with penicillin induced epilepsy]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 20. issue 2. 2012-12-13. PMID:21166209. |
[effect of flunarizine on the epileptiform discharges in cortex and hippocampus of rat with penicillin induced epilepsy]. |
2012-12-13 |
2023-08-12 |
rat |
Michael Stegen, Florian Kirchheim, Alexander Hanuschkin, Ori Staszewski, Rüdiger W Veh, Jakob Wolfar. Adaptive intrinsic plasticity in human dentate gyrus granule cells during temporal lobe epilepsy. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 9. 2012-12-12. PMID:22038909. |
we studied the mechanisms underlying the excitability of human granule cells using acute hippocampal slices obtained during epilepsy surgery. |
2012-12-12 |
2023-08-12 |
human |
C E Adams, J C Yonchek, K M Schulz, S L Graw, J Stitzel, P U Teschke, K E Steven. Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases. Neuroscience. vol 207. 2012-11-27. PMID:22314319. |
these data suggest that reduced chrna7 expression may contribute to the abnormalities in hippocampal inhibitory circuits observed in schizophrenia, autism, and/or epilepsy. |
2012-11-27 |
2023-08-12 |
mouse |
Christine S Cheah, Frank H Yu, Ruth E Westenbroek, Franck K Kalume, John C Oakley, Gregory B Potter, John L Rubenstein, William A Catteral. Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 36. 2012-11-26. PMID:22908258. |
previous studies using a mouse model of ds revealed reduced sodium currents and impaired excitability in gabaergic interneurons in the hippocampus, leading to the hypothesis that impaired excitability of gabaergic inhibitory neurons is the cause of epilepsy and premature death in ds. |
2012-11-26 |
2023-08-12 |
mouse |
Mark William Lopes, Flávia Mahatma Schneider Soares, Nelson de Mello, Jean Costa Nunes, Fabiano Mendes de Cordova, Roger Walz, Rodrigo Bainy Lea. Time-dependent modulation of mitogen activated protein kinases and AKT in rat hippocampus and cortex in the pilocarpine model of epilepsy. Neurochemical research. vol 37. issue 9. 2012-11-20. PMID:22614924. |
time-dependent modulation of mitogen activated protein kinases and akt in rat hippocampus and cortex in the pilocarpine model of epilepsy. |
2012-11-20 |
2023-08-12 |
rat |
Gustavo Silveira, Antonio Carlos Pinheiro de Oliveira, Antonio Lucio Teixeir. Insights into inflammation and epilepsy from the basic and clinical sciences. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 19. issue 8. 2012-11-20. PMID:22705131. |
in accordance with these results, the study of cerebrospinal fluid and brain specimens from patients with chronic epilepsy have shown increased levels of cytokines and areas of hippocampal sclerosis, respectively. |
2012-11-20 |
2023-08-12 |
Not clear |
Telma Luciana Furtado Gouveia, Maria Isabel Berzaghi Frangiotti, Joíse Marques Vieira de Brito, Eduardo Ferreira de Castro Neto, Maisa Mayume Sakata, Andreia Cristina Febba, Dulce Elena Casarini, Débora Amado, Esper Abrão Cavalheiro, Sandro Soares Almeida, Martha Trindade Manchini, Ronaldo Carvalho Araújo, José Antonio Silva, Maria da Graça Naffah-Mazzacoratt. The levels of renin-angiotensin related components are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy. Neurochemistry international. vol 61. issue 1. 2012-11-13. PMID:22542773. |
the levels of renin-angiotensin related components are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy. |
2012-11-13 |
2023-08-12 |
rat |
Telma Luciana Furtado Gouveia, Maria Isabel Berzaghi Frangiotti, Joíse Marques Vieira de Brito, Eduardo Ferreira de Castro Neto, Maisa Mayume Sakata, Andreia Cristina Febba, Dulce Elena Casarini, Débora Amado, Esper Abrão Cavalheiro, Sandro Soares Almeida, Martha Trindade Manchini, Ronaldo Carvalho Araújo, José Antonio Silva, Maria da Graça Naffah-Mazzacoratt. The levels of renin-angiotensin related components are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy. Neurochemistry international. vol 61. issue 1. 2012-11-13. PMID:22542773. |
angiotensin at1 and at2 receptors, mas mrna receptors and angiotensin converting enzyme (ace), tonin and neutral endopeptidase (nep) mrna were also quantified at the hippocampus of wistar rats by real time pcr, during acute (n=10), silent (n=10) and chronic (n=10) phases of pilocarpine-induced epilepsy. |
2012-11-13 |
2023-08-12 |
rat |
Telma Luciana Furtado Gouveia, Maria Isabel Berzaghi Frangiotti, Joíse Marques Vieira de Brito, Eduardo Ferreira de Castro Neto, Maisa Mayume Sakata, Andreia Cristina Febba, Dulce Elena Casarini, Débora Amado, Esper Abrão Cavalheiro, Sandro Soares Almeida, Martha Trindade Manchini, Ronaldo Carvalho Araújo, José Antonio Silva, Maria da Graça Naffah-Mazzacoratt. The levels of renin-angiotensin related components are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy. Neurochemistry international. vol 61. issue 1. 2012-11-13. PMID:22542773. |
herein, we demonstrated for the first time, changes in angiotensin-related peptides, their receptors as well as the releasing enzymes in the hippocampus of rats during pilocarpine-induced epilepsy. |
2012-11-13 |
2023-08-12 |
rat |