Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Dane W Grasse, Suganya Karunakaran, Karen A Moxo. Neuronal synchrony and the transition to spontaneous seizures. Experimental neurology. vol 248. 2013-11-27. PMID:23707218. |
here, we examined the relationship between the on-going local field potential (lfp) and the activity of populations of hippocampal neurons during the transition to spontaneous seizures in the pilocarpine rat model of epilepsy. |
2013-11-27 |
2023-08-12 |
human |
David C Henshal. MicroRNAs in the pathophysiology and treatment of status epilepticus. Frontiers in molecular neuroscience. vol 6. 2013-11-27. PMID:24282394. |
prolonged seizures (status epilepticus, se) can cause damage to brain regions such as the hippocampus and result in cognitive deficits and the pathogenesis of epilepsy. |
2013-11-27 |
2023-08-12 |
Not clear |
Rubén Armañanzas, Lidia Alonso-Nanclares, Jesús Defelipe-Oroquieta, Asta Kastanauskaite, Rafael G de Sola, Javier Defelipe, Concha Bielza, Pedro Larrañag. Machine learning approach for the outcome prediction of temporal lobe epilepsy surgery. PloS one. vol 8. issue 4. 2013-11-26. PMID:23646148. |
we have generated models capable of predicting whether a patient with tle secondary to hippocampal sclerosis will fully recover from epilepsy or not. |
2013-11-26 |
2023-08-12 |
Not clear |
Dalia Kasperaviciute, Claudia B Catarino, Mar Matarin, Costin Leu, Jan Novy, Anna Tostevin, Bárbara Leal, Ellen V S Hessel, Kerstin Hallmann, Michael S Hildebrand, Hans-Henrik M Dahl, Mina Ryten, Daniah Trabzuni, Adaikalavan Ramasamy, Saud Alhusaini, Colin P Doherty, Thomas Dorn, Jörg Hansen, Günter Krämer, Bernhard J Steinhoff, Dominik Zumsteg, Susan Duncan, Reetta K Kälviäinen, Kai J Eriksson, Anne-Mari Kantanen, Massimo Pandolfo, Ursula Gruber-Sedlmayr, Kurt Schlachter, Eva M Reinthaler, Elisabeth Stogmann, Fritz Zimprich, Emilie Théâtre, Colin Smith, Terence J O'Brien, K Meng Tan, Slave Petrovski, Angela Robbiano, Roberta Paravidino, Federico Zara, Pasquale Striano, Michael R Sperling, Russell J Buono, Hakon Hakonarson, João Chaves, Paulo P Costa, Berta M Silva, António M da Silva, Pierre N E de Graan, Bobby P C Koeleman, Albert Becker, Susanne Schoch, Marec von Lehe, Philipp S Reif, Felix Rosenow, Felicitas Becker, Yvonne Weber, Holger Lerche, Karl Rössler, Michael Buchfelder, Hajo M Hamer, Katja Kobow, Roland Coras, Ingmar Blumcke, Ingrid E Scheffer, Samuel F Berkovic, Michael E Weale, Norman Delanty, Chantal Depondt, Gianpiero L Cavalleri, Wolfram S Kunz, Sanjay M Sisodiy. Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Brain : a journal of neurology. vol 136. issue Pt 10. 2013-11-25. PMID:24014518. |
epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. |
2013-11-25 |
2023-08-12 |
human |
Dalia Kasperaviciute, Claudia B Catarino, Mar Matarin, Costin Leu, Jan Novy, Anna Tostevin, Bárbara Leal, Ellen V S Hessel, Kerstin Hallmann, Michael S Hildebrand, Hans-Henrik M Dahl, Mina Ryten, Daniah Trabzuni, Adaikalavan Ramasamy, Saud Alhusaini, Colin P Doherty, Thomas Dorn, Jörg Hansen, Günter Krämer, Bernhard J Steinhoff, Dominik Zumsteg, Susan Duncan, Reetta K Kälviäinen, Kai J Eriksson, Anne-Mari Kantanen, Massimo Pandolfo, Ursula Gruber-Sedlmayr, Kurt Schlachter, Eva M Reinthaler, Elisabeth Stogmann, Fritz Zimprich, Emilie Théâtre, Colin Smith, Terence J O'Brien, K Meng Tan, Slave Petrovski, Angela Robbiano, Roberta Paravidino, Federico Zara, Pasquale Striano, Michael R Sperling, Russell J Buono, Hakon Hakonarson, João Chaves, Paulo P Costa, Berta M Silva, António M da Silva, Pierre N E de Graan, Bobby P C Koeleman, Albert Becker, Susanne Schoch, Marec von Lehe, Philipp S Reif, Felix Rosenow, Felicitas Becker, Yvonne Weber, Holger Lerche, Karl Rössler, Michael Buchfelder, Hajo M Hamer, Katja Kobow, Roland Coras, Ingmar Blumcke, Ingrid E Scheffer, Samuel F Berkovic, Michael E Weale, Norman Delanty, Chantal Depondt, Gianpiero L Cavalleri, Wolfram S Kunz, Sanjay M Sisodiy. Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Brain : a journal of neurology. vol 136. issue Pt 10. 2013-11-25. PMID:24014518. |
these findings suggest scn1a involvement in a common epilepsy syndrome, give new direction to biological understanding of mesial temporal lobe epilepsy with hippocampal sclerosis with febrile seizures, and open avenues for investigation of prognostic factors and possible prevention of epilepsy in some children with febrile seizures. |
2013-11-25 |
2023-08-12 |
human |
Zechun Peng, Nianhui Zhang, Weizheng Wei, Christine S Huang, Yliana Cetina, Thomas S Otis, Carolyn R House. A reorganized GABAergic circuit in a model of epilepsy: evidence from optogenetic labeling and stimulation of somatostatin interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 36. 2013-11-15. PMID:24005292. |
the goal of this study was to determine whether somatostatin (som)-expressing neurons in stratum (s.) oriens of the hippocampus exhibit axonal sprouting beyond their normal territory and innervate granule cells of the dentate gyrus in a pilocarpine model of epilepsy. |
2013-11-15 |
2023-08-12 |
mouse |
Sallie Baxendale, Pamela J Thompson, Josemir W Sande. Neuropsychological outcomes in epilepsy surgery patients with unilateral hippocampal sclerosis and good preoperative memory function. Epilepsia. vol 54. issue 9. 2013-11-13. PMID:23875960. |
neuropsychological outcomes in epilepsy surgery patients with unilateral hippocampal sclerosis and good preoperative memory function. |
2013-11-13 |
2023-08-12 |
Not clear |
Sallie Baxendale, Pamela J Thompson, Josemir W Sande. Neuropsychological outcomes in epilepsy surgery patients with unilateral hippocampal sclerosis and good preoperative memory function. Epilepsia. vol 54. issue 9. 2013-11-13. PMID:23875960. |
we examined postoperative changes in the memory function of 68 people with unilateral hippocampal sclerosis (hs) who underwent epilepsy surgery and had no previous clinical memory impairments. |
2013-11-13 |
2023-08-12 |
Not clear |
Xavier Ekolle Ndode-Ekane, Asla Pitkäne. Urokinase-type plasminogen activator receptor modulates epileptogenesis in mouse model of temporal lobe epilepsy. Molecular neurobiology. vol 47. issue 3. 2013-11-11. PMID:23263886. |
the more severe epilepsy phenotype in upar-/- mice was associated with delayed but augmented inflammatory response and more severe neurodegeneration in the hippocampus. |
2013-11-11 |
2023-08-12 |
mouse |
Yuanzhen Ye, Jiajia Xiong, Jun Hu, Min Kong, Li Cheng, Hengsheng Chen, Tingsong Li, Li Jian. Altered hippocampal myelinated fiber integrity in a lithium-pilocarpine model of temporal lobe epilepsy: a histopathological and stereological investigation. Brain research. vol 1522. 2013-10-23. PMID:23727401. |
investigated by electroencephalography (eeg), gallyas silver staining, immunohistochemistry, western blotting, transmission electron microscopy, and stereological methods, the results showed that hippocampal myelinated fibers of the epilepsy group were degenerated with significantly less myelin basic protein (mbp) expression relative to those of control group rats. |
2013-10-23 |
2023-08-12 |
rat |
Yuanzhen Ye, Jiajia Xiong, Jun Hu, Min Kong, Li Cheng, Hengsheng Chen, Tingsong Li, Li Jian. Altered hippocampal myelinated fiber integrity in a lithium-pilocarpine model of temporal lobe epilepsy: a histopathological and stereological investigation. Brain research. vol 1522. 2013-10-23. PMID:23727401. |
stereological analysis revealed that the total volumes of hippocampal formation, myelinated fibers, and myelin sheaths in the hippocampus of epilepsy group rats were decreased by 20.43%, 49.16%, and 52.60%, respectively. |
2013-10-23 |
2023-08-12 |
rat |
Yuanzhen Ye, Jiajia Xiong, Jun Hu, Min Kong, Li Cheng, Hengsheng Chen, Tingsong Li, Li Jian. Altered hippocampal myelinated fiber integrity in a lithium-pilocarpine model of temporal lobe epilepsy: a histopathological and stereological investigation. Brain research. vol 1522. 2013-10-23. PMID:23727401. |
finally, the total length of the myelinated fibers in the hippocampus of epilepsy group rats was significantly decreased by 56.92%, compared to that of the control group, with the decreased length most prominent for myelinated fibers with diameters from 0.4 to 0.8µm. |
2013-10-23 |
2023-08-12 |
rat |
Marta Rattka, Claudia Brandt, Wolfgang Lösche. The intrahippocampal kainate model of temporal lobe epilepsy revisited: epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats. Epilepsy research. vol 103. issue 2-3. 2013-10-22. PMID:23196211. |
epilepsy was associated with increased behavioral excitability and impaired learning and memory in a water maze, most likely as a result of hippocampal pathology, which was characterized by extensive neuronal loss in ca3 and dentate hilus and dispersion of granule cells in the ipsilateral hippocampus. |
2013-10-22 |
2023-08-12 |
human |
Lucas P Schilling, Renata R Kieling, Tharick A Pascoal, Hyoung-Ihl Kim, Min Cheol Lee, Yun Hee Kim, Eliseu Paglioli, Pedro R Neto, Jaderson C Costa, Andre Palmin. Bilateral perisylvian ulegyria: an under-recognized, surgically remediable epileptic syndrome. Epilepsia. vol 54. issue 8. 2013-10-22. PMID:23586600. |
we report a series of patients with epilepsy and pseudobulbar palsy due to bilateral perisylvian ulg (bp-ulg), show that hippocampal sclerosis (hs) is often associated and highlight the fact that in this entity, unlike in malformative bilateral perisylvian pmg, seizures may be surgically treated. |
2013-10-22 |
2023-08-12 |
Not clear |
Rebecca L Williams-Karnesky, Ursula S Sandau, Theresa A Lusardi, Nikki K Lytle, Joseph M Farrell, Eleanor M Pritchard, David L Kaplan, Detlev Boiso. Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. The Journal of clinical investigation. vol 123. issue 8. 2013-10-22. PMID:23863710. |
this transient therapeutic intervention reversed the dna hypermethylation seen in the epileptic brain, inhibited sprouting of mossy fibers in the hippocampus, and prevented the progression of epilepsy for at least 3 months. |
2013-10-22 |
2023-08-12 |
rat |
Nihal Olgac Dundar, Berrin Aktekin, Nilufer Cicek Ekinci, Duygu Sahinturk, Ugur Yavuzer, Olcay Yegin, Senay Haspola. Interleukin-1β secretion in hippocampal sclerosis patients with mesial temporal lobe epilepsy. Neurology international. vol 5. issue 3. 2013-10-22. PMID:24147214. |
mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) is a common medically intractable epilepsy syndrome. |
2013-10-22 |
2023-08-12 |
Not clear |
Shabeesh Balan, Saradalekshmi Koramannil Radhab, Koramannil Radha, Sanish Sathyan, Joseph Vijai, Moinak Banerjee, Kurupath Radhakrishna. Major vault protein (MVP) gene polymorphisms and drug resistance in mesial temporal lobe epilepsy with hippocampal sclerosis. Gene. vol 526. issue 2. 2013-10-18. PMID:23751308. |
to investigate the relationship between single nucleotide polymorphisms (snps) involving the mvp gene and aed-resistance, we compared the distribution of three snps in the mvp gene, rs4788187, rs3815824 and rs3815823, among 220 patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) (prototype of aed-resistant epilepsy syndrome), 201 patients with juvenile myoclonic epilepsy (jme) (prototype of aed-responsive epilepsy syndrome) and 213 ethnically matched non-epilepsy controls. |
2013-10-18 |
2023-08-12 |
human |
L C Harte-Hargrove, N J Maclusky, H E Scharfma. Brain-derived neurotrophic factor-estrogen interactions in the hippocampal mossy fiber pathway: implications for normal brain function and disease. Neuroscience. vol 239. 2013-10-17. PMID:23276673. |
we suggest that the interactions between bdnf and 17β-estradiol in the mfs are potentially important in the normal function of the hippocampus, and have implications for sex differences in functions that depend on the mfs and in diseases where mf plasticity has been suggested to play an important role, alzheimer's disease, epilepsy and addiction. |
2013-10-17 |
2023-08-12 |
Not clear |
Ning Chen, Na Yan, Chong Liu, Yan Ge, Jian-Guo Zhang, Fan-Gang Men. Neuroprotective effects of electrical stimulation of the anterior nucleus of the thalamus for hippocampus neurons in intractable epilepsy. Medical hypotheses. vol 80. issue 5. 2013-09-30. PMID:23481284. |
neuroprotective effects of electrical stimulation of the anterior nucleus of the thalamus for hippocampus neurons in intractable epilepsy. |
2013-09-30 |
2023-08-12 |
Not clear |
J Win Mar Salmah, A Noorfizura, A Mohd Shafie, A Helmy, A R Salmi, L Nain. Hippocampal MR Volumetric Studies in Paediatric Patients with Epilepsy and Normal Controls. The neuroradiology journal. vol 24. issue 4. 2013-09-25. PMID:24059706. |
hippocampal mr volumetric studies in paediatric patients with epilepsy and normal controls. |
2013-09-25 |
2023-08-12 |
human |