| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Layer, C E Elger, M Reise. [Magnetic resonance tomography in epilepsy]. Der Radiologe. vol 33. issue 4. 1993-07-08. PMID:8506404. |
the most important causes of focal epilepsy are hippocampal sclerosis, circumscribed tumors, vascular malformations, trauma and perinatal damage. |
1993-07-08 |
2023-08-12 |
Not clear |
| K A Harris, G A Oyler, G M Doolittle, I Vincent, R A Lehman, R L Kincaid, M L Billingsle. Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices. Annals of neurology. vol 33. issue 1. 1993-06-16. PMID:8494335. |
slices of human lateral temporal cortex were obtained from tissues removed incidental to resections for intractable hippocampal epilepsy. |
1993-06-16 |
2023-08-12 |
human |
| H Lahtinen, R Miettinen, A Ylinen, T Halonen, P J Riekkine. Biochemical and morphological changes in the rat hippocampus following transection of the fimbria-fornix. Brain research bulletin. vol 31. issue 3-4. 1993-06-11. PMID:8098258. |
according to electrophysiological studies, the subcortically denervated hippocampus has been suggested as a model for limbic epilepsy. |
1993-06-11 |
2023-08-12 |
human |
| H Lahtinen, R Miettinen, A Ylinen, T Halonen, P J Riekkine. Biochemical and morphological changes in the rat hippocampus following transection of the fimbria-fornix. Brain research bulletin. vol 31. issue 3-4. 1993-06-11. PMID:8098258. |
we investigated a) whether fimbrial lesioning leads to any biochemical or morphological changes in the rat hippocampus, b) if these changes give any explanation to the previously indicated hyperexcitability, and c) if the changes are in line with the findings in other experimental models and human epilepsy. |
1993-06-11 |
2023-08-12 |
human |
| C T Pappa. Epilepsy surgery for hippocampal sclerosis. The Western journal of medicine. vol 158. issue 1. 1993-05-11. PMID:8470396. |
epilepsy surgery for hippocampal sclerosis. |
1993-05-11 |
2023-08-12 |
Not clear |
| M Isokawa, M F Levesque, T L Babb, J Enge. Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 4. 1993-05-06. PMID:8463831. |
previous histological and immunocytochemical studies suggest that reorganization of the dentate granule cell axons, the mossy fibers, can occur in epileptic human hippocampus (sutula et al., 1989; houser et al., 1990; babb et al., 1991) and in animal models of epilepsy (tauck and nadler, 1985; sutula et al., 1988; cronin et al., 1992). |
1993-05-06 |
2023-08-12 |
human |
| M Isokawa, M F Levesque, T L Babb, J Enge. Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 4. 1993-05-06. PMID:8463831. |
individual mossy fibers were directly visualized by injecting a tracer (biocytin or lucifer yellow) intracellularly in hippocampal slices prepared from temporal lobes that were surgically removed from patients for treatment of intractable epilepsy. |
1993-05-06 |
2023-08-12 |
human |
| M Isokawa, M F Levesque, T L Babb, J Enge. Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 4. 1993-05-06. PMID:8463831. |
the lack of control slices from normal living human hippocampus makes it difficult to assess to what extent the present findings are epilepsy associated. |
1993-05-06 |
2023-08-12 |
human |
| N Hawrylak, F L Chang, W T Greenoug. Astrocytic and synaptic response to kindling in hippocampal subfield CA1. II. Synaptogenesis and astrocytic process increases to in vivo kindling. Brain research. vol 603. issue 2. 1993-05-03. PMID:8461984. |
this report provides morphological evidence that the periodic electrical stimulation used in the kindling model of epilepsy induces astrocytic hypertrophy and an increase in shaft synapse density in the ca1 region of the hippocampus. |
1993-05-03 |
2023-08-12 |
rat |
| J Mellanby, J Dwyer, C A Hawkins, C Hitche. Effect of experimental limbic epilepsy on the estrus cycle and reproductive success in rats. Epilepsia. vol 34. issue 2. 1993-04-20. PMID:8453929. |
epilepsy was induced in female rats by the injection of tetanus toxin (5 mouse ld50) unilaterally into the ventral hippocampus under anesthesia. |
1993-04-20 |
2023-08-12 |
mouse |
| K Mutoh, M Ito, H Tsuda, H Shiraishi, K Oguro, Y Shirasaka, T Okuno, H Mikaw. Depth EEG in mutant epileptic E1 mice: demonstration of secondary generalization of the seizure from the hippocampus. Electroencephalography and clinical neurophysiology. vol 86. issue 3. 1993-04-19. PMID:7680997. |
mutant epileptic e1 mice are thought to have focal epilepsy of hippocampal origin because glucose utilization is increased in the hippocampus (hpc) during seizures in these mice. |
1993-04-19 |
2023-08-12 |
mouse |
| M Mülle. Morphological and functional consequences of chronic epilepsy in rat hippocampal slice cultures. Pflugers Archiv : European journal of physiology. vol 422. issue 4. 1993-03-22. PMID:8437894. |
morphological and functional consequences of chronic epilepsy in rat hippocampal slice cultures. |
1993-03-22 |
2023-08-12 |
human |
| M Mülle. Morphological and functional consequences of chronic epilepsy in rat hippocampal slice cultures. Pflugers Archiv : European journal of physiology. vol 422. issue 4. 1993-03-22. PMID:8437894. |
these changes were similar to those observed previously in post-mortem studies of hippocampal tissue from human epilepsy patients. |
1993-03-22 |
2023-08-12 |
human |
| J W Swann, K L Smith, C M Gómez, R J Brad. The ontogeny of hippocampal local circuits and focal epileptogenesis. Epilepsy research. Supplement. vol 9. 1993-03-15. PMID:1285904. |
this miswiring of hippocampal networks might be responsible for the marked seizure susceptibility into adulthood and might even contribute to complex partial epilepsy in individuals with a history of childhood seizures. |
1993-03-15 |
2023-08-11 |
Not clear |
| L E Mello, E A Cavalheiro, A M Tan, J K Pretorius, T L Babb, D M Finc. Granule cell dispersion in relation to mossy fiber sprouting, hippocampal cell loss, silent period and seizure frequency in the pilocarpine model of epilepsy. Epilepsy research. Supplement. vol 9. 1993-03-15. PMID:1285914. |
granule cell dispersion in relation to mossy fiber sprouting, hippocampal cell loss, silent period and seizure frequency in the pilocarpine model of epilepsy. |
1993-03-15 |
2023-08-11 |
Not clear |
| A Represa, Y Ben-Ar. Kindling is associated with the formation of novel mossy fibre synapses in the CA3 region. Experimental brain research. vol 92. issue 1. 1993-02-23. PMID:1486956. |
the morphological changes reported here may represent a histopathological substrate for the epilepsy in the absence of overt signs of a hippocampal lesion. |
1993-02-23 |
2023-08-11 |
rat |
| M Müller, B H Gähwiler, L Rietschin, S M Thompso. Reversible loss of dendritic spines and altered excitability after chronic epilepsy in hippocampal slice cultures. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 1. 1993-02-08. PMID:8093558. |
reversible loss of dendritic spines and altered excitability after chronic epilepsy in hippocampal slice cultures. |
1993-02-08 |
2023-08-12 |
human |
| W Lasoń, B Przewłocka, R Przewłock. The prodynorphin system in the rat hippocampus is differentially influenced by kainic acid and pentetrazole. Neuroscience. vol 51. issue 2. 1993-01-19. PMID:1465197. |
three and 24 h after pentetrazole administration the level of prodynorphin mrna in the dentate gyrus was slightly decreased (by c. 30%), but was back to the control values after 72 h. hence seizure-related changes in hippocampal prodynorphin neuron activity seem to depend on the experimental model of epilepsy. |
1993-01-19 |
2023-08-11 |
rat |
| R R Trifiletti, M R Pranzatell. ACTH binds to [3H]MK-801-labelled rat hippocampal NMDA receptors. European journal of pharmacology. vol 226. issue 4. 1992-11-23. PMID:1327849. |
to explore the possible role of excitatory amino acid receptors, we studied the influence of acth and acth fragments in vitro on the binding of [3h]mk-801 to rat hippocampus, a region relevant to epilepsy. |
1992-11-23 |
2023-08-11 |
rat |
| D Zhao, L S Leun. Hippocampal kindling induced paired-pulse depression in the dentate gyrus and paired-pulse facilitation in CA3. Brain research. vol 582. issue 1. 1992-09-14. PMID:1498679. |
rats received high frequency (100 hz, 1 s) hippocampal stimulations that evoked afterdischarges (ads) in a partial kindling model of epilepsy. |
1992-09-14 |
2023-08-11 |
rat |