Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Gary W Mathern, P David Adelson, Leslie D Cahan, Joao P Leit. Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Progress in brain research. vol 135. 2002-08-22. PMID:12143344. |
hippocampal neuron damage in human epilepsy: meyer's hypothesis revisited. |
2002-08-22 |
2023-08-12 |
human |
Gary W Mathern, P David Adelson, Leslie D Cahan, Joao P Leit. Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Progress in brain research. vol 135. 2002-08-22. PMID:12143344. |
whether hippocampal neuron loss and/or hippocampal sclerosis is the 'cause' or 'consequence' of seizures has been a fundamental question in human epilepsy studies for over a century. |
2002-08-22 |
2023-08-12 |
human |
Darrell V Lewis, Daniel P Barboriak, James R MacFall, James M Provenzale, Teresa V Mitchell, Kevan E VanLandingha. Do prolonged febrile seizures produce medial temporal sclerosis? Hypotheses, MRI evidence and unanswered questions. Progress in brain research. vol 135. 2002-08-22. PMID:12143347. |
whether or not severe febrile seizures in infancy cause hippocampal injury and subsequent medial temporal sclerosis is an often debated question in epilepsy. |
2002-08-22 |
2023-08-12 |
Not clear |
William H Theodore, William D Gaillar. Neuroimaging and the progression of epilepsy. Progress in brain research. vol 135. 2002-08-22. PMID:12143351. |
in patients with temporal lobe epilepsy, structural magnetic resonance imaging (mri) has shown volume reductions ipsilateral to the epileptic focus in hippocampal and extrahippocampal regions; the former, in cross-sectional studies, increase with increasing epilepsy duration. |
2002-08-22 |
2023-08-12 |
human |
Hennric Jokeit, Alois Ebne. Effects of chronic epilepsy on intellectual functions. Progress in brain research. vol 135. 2002-08-22. PMID:12143364. |
similar to several studies on hippocampal neuronal density, hippocampal volume, and glucose metabolism, the presented cross-sectional data demonstrate that a duration of chronic epilepsy exceeding two decades is associated with worse cognitive abilities. |
2002-08-22 |
2023-08-12 |
Not clear |
Xia Zhang, Shu-Sen Cui, Amy E Wallace, Darren K Hannesson, Larry C Schmued, Deborah M Saucier, William G Honer, Michael E Corcora. Relations between brain pathology and temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 14. 2002-08-06. PMID:12122066. |
temporal lobe epilepsy, the most common type of epilepsy in adult humans, is characterized clinically by the progressive development of spontaneous recurrent seizures of temporal lobe origin and pathologically by hippocampal neuronal loss and mossy fiber sprouting. |
2002-08-06 |
2023-08-12 |
rat |
S Pal, D Sun, D Limbrick, A Rafiq, R J DeLorenz. Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell calcium. vol 30. issue 4. 2002-07-31. PMID:11587552. |
epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. |
2002-07-31 |
2023-08-12 |
Not clear |
S Pal, D Sun, D Limbrick, A Rafiq, R J DeLorenz. Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell calcium. vol 30. issue 4. 2002-07-31. PMID:11587552. |
it has been shown that epileptic neurons have altered calcium homeostatic mechanisms following epileptogenesis in the hippocampal neuronal culture (hnc) and pilocarpine models of epilepsy. |
2002-07-31 |
2023-08-12 |
Not clear |
F Wendling, F Bartolomei, J J Bellanger, P Chauve. Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition. The European journal of neuroscience. vol 15. issue 9. 2002-07-26. PMID:12028360. |
it starts with recent hypotheses about: (i) the behaviour of inhibitory interneurons in hippocampal or neocortical networks in the generation of gamma frequency oscillations; (ii) the nonuniform alteration of gabaergic inhibition in experimental epilepsy (reduced dendritic inhibition and increased somatic inhibition); and (iii) the possible depression of gaba(a,fast) circuit activity by gaba(a,slow) inhibitory postsynaptic currents. |
2002-07-26 |
2023-08-12 |
human |
Kazue Igarashi, Hirokazu Oguni, Makiko Osawa, Yutaka Awaya, Motoichiro Kato, Masaru Mimura, Haruo Kashim. Wisconsin card sorting test in children with temporal lobe epilepsy. Brain & development. vol 24. issue 3. 2002-07-16. PMID:11934515. |
to search for the origin of frontal lobe dysfunction identified by the wisconsin card sorting test (wcst) in temporal lobe epilepsy (tle) patients, we investigated the wcst performance among 19 children with tle (with hippocampal atrophy (ha group n=12), without structural lesions (nsl group n=7)), 15 patients with frontal lobe epilepsy (fle group), and age-matched normal controls (n group). |
2002-07-16 |
2023-08-12 |
Not clear |
S Dupon. [MRI exploration of partial epilepsy]. Revue neurologique. vol 158. issue 5 Pt 2. 2002-07-16. PMID:11997747. |
technical progress has included new sequences (3d acquisition, inversion-recovery, fast spin-echo), new imaging planes (through the greater diameter of the hippocampus for temporal epilepsy, orbitao-meatal for extra-temporal epilepsy), high-resolution imaging, and better signal-noise ratio in addition to new procedurs such as nmr spectroscopy, diffusion/perfusion imaging, or functional mri. |
2002-07-16 |
2023-08-12 |
Not clear |
Jon Dobso. Investigation of age-related variations in biogenic magnetite levels in the human hippocampus. Experimental brain research. vol 144. issue 1. 2002-07-12. PMID:11976766. |
the magnetic properties of human hippocampal tissue from 23 subjects (15 epilepsy patients and eight cadavers with no neuropathology) were analysed and tissue concentrations of magnetic material were calculated. |
2002-07-12 |
2023-08-12 |
human |
Paul S Buckmaster, Mary O Smith, Christine L Buckmaster, Richard A LeCouteur, F Edward Dude. Absence of temporal lobe epilepsy pathology in dogs with medically intractable epilepsy. Journal of veterinary internal medicine. vol 16. issue 1. 2002-07-11. PMID:11822812. |
temporal lobe epilepsy is the most common type of epilepsy in adult humans, it is frequently resistant to anticonvulsant therapy, and it is commonly associated with characteristic neuropathological abnormalities in the hippocampal dentate gyrus. |
2002-07-11 |
2023-08-12 |
Not clear |
Maria Thom, Sanjay M Sisodiya, Andrew Beckett, Lillian Martinian, Woan-Ru Lin, William Harkness, Tejal N Mitchell, John Craig, John Duncan, Francesco Scaravill. Cytoarchitectural abnormalities in hippocampal sclerosis. Journal of neuropathology and experimental neurology. vol 61. issue 6. 2002-07-08. PMID:12071634. |
the severity of granule cell disorganization correlated closely with the degree of hippocampal neuronal loss but not with the age at first seizure or a history of a precipitating event for epilepsy such as prolonged febrile seizures. |
2002-07-08 |
2023-08-12 |
human |
József Janszk. [Role of epileptogenic lesions in the development of ictal and interictal epileptic disturbance]. Orvosi hetilap. vol 143. issue 18. 2002-07-03. PMID:12053650. |
tumors, malformations of the cortical development, the hippocampal sclerosis, perinatal lesions, posttraumatic scars and the vascular malformations are the most important morphological abnormalities associated with epilepsy. |
2002-07-03 |
2023-08-12 |
Not clear |
Franck Semah, Catherine Lamy, Sophie Demere. Hippocampal sclerosis and other hippocampal abnormalities in the early identification of candidates for epilepsy surgery. Archives of neurology. vol 59. issue 6. 2002-07-01. PMID:12056946. |
hippocampal sclerosis and other hippocampal abnormalities in the early identification of candidates for epilepsy surgery. |
2002-07-01 |
2023-08-12 |
Not clear |
M Thom, S M Sisodiya, W R Lin, T Mitchell, S L Free, J Stevens, F Scaravill. Bilateral isolated hippocampal malformation in temporal lobe epilepsy. Neurology. vol 58. issue 11. 2002-06-27. PMID:12058101. |
hippocampal malformations in patients with epilepsy usually are reported in the context of widespread cortical malformations. |
2002-06-27 |
2023-08-12 |
Not clear |
Furong Yu, Zhuo Guan, Ming Zhuo, Lanying Sun, Weiguo Zou, Zhongcheng Zheng, Xinyuan Li. Further identification of NSF* as an epilepsy related gene. Brain research. Molecular brain research. vol 99. issue 2. 2002-06-25. PMID:11978405. |
in this study, using phosphorothioate oligodeoxynucleotide (ps-odn), an antisense of nsf to downregulate the function of nsf in vitro cultured hippocampus neurons and pc12, this treatment simultaneously induced enhancement of the neurite outgrowth of hippocampal neurons and pc12, a phenomenon similar to the structural changes following epilepsy. |
2002-06-25 |
2023-08-12 |
Not clear |
A A MORRI. Temporal lobectomy with removal of uncus, hippocampus, and amygdala; results for psychomotor epilepsy three to nine years after operation. A.M.A. archives of neurology and psychiatry. vol 76. issue 5. 2002-05-01. PMID:13371963. |
temporal lobectomy with removal of uncus, hippocampus, and amygdala; results for psychomotor epilepsy three to nine years after operation. |
2002-05-01 |
2023-08-12 |
Not clear |
Tadao Kawamura, Takato Morioka, Shunji Nishio, Kimiko Fukui, Ryo Yamasaki, Muneaki Matsu. Temporal lobe epilepsy associated with hippocampal sclerosis and a contralateral middle fossa arachnoid cyst. Seizure. vol 11. issue 1. 2002-04-30. PMID:11888263. |
acmcf was not considered the direct cause of epilepsy; instead the seizures were attributed to hippocampal sclerosis. |
2002-04-30 |
2023-08-12 |
Not clear |