| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Walz, R M R P S Castro, T R Velasco, V Alexandre, M H Lopes, J P Leite, A C Santos, J A Assirati, L Wichert-Ana, V C Terra-Bustamante, M M Bianchin, P C Maciag, K B Ribeiro, R Guarnieri, D Araújo, O Cabalero, R Moura, A C M Salim, K Kindlmann, M C Landemberger, W Marques, R M F Fernandes, L N Serafini, H R Machado, C G Carlotti, R R Brentani, A C Sakamoto, V R Martin. Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant. Neurology. vol 61. issue 9. 2004-01-14. PMID:14610121. |
ablation of the cellular prion protein (prp(c)) gene (prnp) enhances neuronal excitability of the hippocampus in vitro and sensitivity to seizure in vivo, indicating that prp(c) might be related to epilepsy. |
2004-01-14 |
2023-08-12 |
Not clear |
| Zhouyan Feng, Dominique M Duran. Low-calcium epileptiform activity in the hippocampus in vivo. Journal of neurophysiology. vol 90. issue 4. 2004-01-05. PMID:14534265. |
this type of low-calcium nonsynaptic epilepsy model in an intact hippocampus could play an important role in revealing additional mechanisms of epilepsy disorders and in developing novel anti-convulsant drugs. |
2004-01-05 |
2023-08-12 |
rat |
| Fulvio Alexandre Scorza, Ricardo Mario Arida, Roberta Monterazzo Cysneiros, Margareth Rose Priel, Marly de Albuquerque, Esper Abrão Cavalheir. The effects of alcohol intake and withdrawal on the seizures frequency and hippocampal morphology in rats with epilepsy. Neuroscience research. vol 47. issue 3. 2004-01-05. PMID:14568114. |
the effects of alcohol intake and withdrawal on the seizures frequency and hippocampal morphology in rats with epilepsy. |
2004-01-05 |
2023-08-12 |
rat |
| Fulvio Alexandre Scorza, Ricardo Mario Arida, Roberta Monterazzo Cysneiros, Margareth Rose Priel, Marly de Albuquerque, Esper Abrão Cavalheir. The effects of alcohol intake and withdrawal on the seizures frequency and hippocampal morphology in rats with epilepsy. Neuroscience research. vol 47. issue 3. 2004-01-05. PMID:14568114. |
the neo-timm and nissl staining of hippocampal formation and of the dentate gyrus in rats with epilepsy showed a cell loss in the hippocampal subfield ca1 and in the hillus of dentate gyrus. |
2004-01-05 |
2023-08-12 |
rat |
| Fulvio Alexandre Scorza, Ricardo Mario Arida, Roberta Monterazzo Cysneiros, Margareth Rose Priel, Marly de Albuquerque, Esper Abrão Cavalheir. The effects of alcohol intake and withdrawal on the seizures frequency and hippocampal morphology in rats with epilepsy. Neuroscience research. vol 47. issue 3. 2004-01-05. PMID:14568114. |
in rats with epilepsy with alcohol intake, we observed a cell loss in hippocampal subfields ca3 and hillus of the dentate gyrus, with significant neuronal death in subfield ca1, when compared with control animals. |
2004-01-05 |
2023-08-12 |
rat |
| H Zhu, C Zhu, J Hao, X Meng, L Wang, D Che. Screening of novel epilepsy-related genes and isolation and identification of cDNAs. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao. vol 20. issue 1. 2003-12-16. PMID:12845744. |
since the microtubulin-associated protein is closely associated with the collateral sprouting of mossy fibers in the hippocampus of seizured rat, the high expression of erg14 in the early stage of epilepsy might predict the growth of axon and formation of synapse. |
2003-12-16 |
2023-08-12 |
rat |
| Liri Jin, Yanbin Jia, Boyu Zhang, Qi Xu, Yu Fan, Liwen Wu, Yan She. Association analysis of a polymorphism of interleukin 1 beta (IL-1 beta) gene with temporal lobe epilepsy in a Chinese population. Epilepsia. vol 44. issue 10. 2003-11-25. PMID:14510824. |
temporal lobe epilepsy with hippocampal sclerosis (tle-hs+) is one of the most common medically intractable epilepsies. |
2003-11-25 |
2023-08-12 |
Not clear |
| João O Malva, Ana P Silva, Rodrigo A Cunh. Presynaptic modulation controlling neuronal excitability and epileptogenesis: role of kainate, adenosine and neuropeptide Y receptors. Neurochemical research. vol 28. issue 10. 2003-11-18. PMID:14570395. |
particular emphasis is given on the robust neuromodulatory role of these three groups of receptors on the release of glutamate in the hippocampus, a main focus of epilepsy. |
2003-11-18 |
2023-08-12 |
Not clear |
| Tae-Cheon Kang, Sung-Jin An, Seung-Kook Park, In-Koo Hwang, Moo Ho Wo. P2X2 and P2X4 receptor expression is regulated by a GABA(A) receptor-mediated mechanism in the gerbil hippocampus. Brain research. Molecular brain research. vol 116. issue 1-2. 2003-11-17. PMID:12941474. |
here we show that, in the seizure-sensitive (ss) gerbil hippocampus, a recognized genetic epilepsy model, the expressions of both p2x2 and p2x4 receptors are markedly decreased as compared with that in the seizure-resistant (sr) gerbil. |
2003-11-17 |
2023-08-12 |
Not clear |
| Jack M Paren. Injury-induced neurogenesis in the adult mammalian brain. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 9. issue 4. 2003-11-10. PMID:12934709. |
studies of dentate gyrus neurogenesis in adult rodent epilepsy models suggest that seizure-induced neurogenesis involves aberrant neuroblast migration and integration that may contribute to persistent hippocampal hyperexcitability. |
2003-11-10 |
2023-08-12 |
rat |
| Claudia Brandt, Maike Glien, Heidrun Potschka, Holger Volk, Wolfgang Lösche. Epileptogenesis and neuropathology after different types of status epilepticus induced by prolonged electrical stimulation of the basolateral amygdala in rats. Epilepsy research. vol 55. issue 1-2. 2003-10-23. PMID:12948619. |
these different forms of ssse induce epilepsy with srs and brain pathology reminiscent of temporal lobe epilepsy with hippocampal sclerosis. |
2003-10-23 |
2023-08-12 |
rat |
| Waney Squier, Helen Salisbury, Sanjay Sisodiy. Stroke in the developing brain and intractable epilepsy: effect of timing on hippocampal sclerosis. Developmental medicine and child neurology. vol 45. issue 9. 2003-10-09. PMID:12948324. |
stroke in the developing brain and intractable epilepsy: effect of timing on hippocampal sclerosis. |
2003-10-09 |
2023-08-12 |
Not clear |
| Hernando Rafae. Clinical prospects for neural grafting therapy for hippocampal lesions and epilepsy. Neurosurgery. vol 53. issue 3. 2003-10-08. PMID:12959107. |
clinical prospects for neural grafting therapy for hippocampal lesions and epilepsy. |
2003-10-08 |
2023-08-12 |
Not clear |
| R Edward Hogan, Richard D Bucholz, Sarang Josh. Hippocampal deformation-based shape analysis in epilepsy and unilateral mesial temporal sclerosis. Epilepsia. vol 44. issue 6. 2003-10-06. PMID:12790893. |
hippocampal deformation-based shape analysis in epilepsy and unilateral mesial temporal sclerosis. |
2003-10-06 |
2023-08-12 |
Not clear |
| Stefan Remy, Bernd W Urban, Christian E Elger, Heinz Bec. Anticonvulsant pharmacology of voltage-gated Na+ channels in hippocampal neurons of control and chronically epileptic rats. The European journal of neuroscience. vol 17. issue 12. 2003-09-24. PMID:12823472. |
we have, therefore, analysed the effects of phenytoin (100 micro m), lamotrigine (100 micro m) and valproate (600 micro m) on na+ currents in dissociated rat hippocampal granule neurons in the pilocarpine model of chronic epilepsy. |
2003-09-24 |
2023-08-12 |
rat |
| Marie-Aude Rigoulot, Claire Leroy, Estelle Koning, Arielle Ferrandon, Astrid Nehli. Prolonged low-dose caffeine exposure protects against hippocampal damage but not against the occurrence of epilepsy in the lithium-pilocarpine model in the rat. Epilepsia. vol 44. issue 4. 2003-09-09. PMID:12681001. |
prolonged low-dose caffeine exposure protects against hippocampal damage but not against the occurrence of epilepsy in the lithium-pilocarpine model in the rat. |
2003-09-09 |
2023-08-12 |
rat |
| Roland A Bender, Sheila V Soleymani, Amy L Brewster, Snow T Nguyen, Heinz Beck, Gary W Mathern, Tallie Z Bara. Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 17. 2003-09-03. PMID:12890777. |
these findings indicate that the expression of hcn isoforms is dynamically regulated in human as well as in experimental hippocampal epilepsy. |
2003-09-03 |
2023-08-12 |
human |
| X R Zhang, D Han, Y F Tang, M L Liu, S J Yi. Possible role of dentate gyrus in greneration of rat temporal lobe epilepsy induced by electrical stimulation. Sheng li xue bao : [Acta physiologica Sinica]. vol 53. issue 3. 2003-08-29. PMID:12589411. |
possible role of the dentate gyrus (dg) and the hippocampus (hpc) in temporal lobe epileptogensis was investigated in an electrogenic model of rat epilepsy. |
2003-08-29 |
2023-08-12 |
rat |
| Sirpa Rainesalo, Tapani Keränen, Jukka Peltola, Pirjo Saransaar. Glutamate uptake in blood platelets from epileptic patients. Neurochemistry international. vol 43. issue 4-5. 2003-08-19. PMID:12742083. |
we studied glutamate uptake into blood platelets from patients with distinct epileptic syndromes: included were 20 patients with temporal lobe epilepsy and hippocampal sclerosis (tle+hs), 20 with juvenile myoclonus epilepsy (jme) and 20 healthy volunteers matched for age and sex. |
2003-08-19 |
2023-08-12 |
human |
| C Brandt, H Potschka, W Löscher, U Eber. N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in the kainate model of temporal lobe epilepsy. Neuroscience. vol 118. issue 3. 2003-08-08. PMID:12710980. |
the massive neurodegeneration in the hippocampus is known as hippocampal sclerosis, and is considered one of the hallmarks of this type of difficult-to-treat epilepsy. |
2003-08-08 |
2023-08-12 |
rat |