| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David A Narvaiz, Katherine J Blandin, D Gregory Sullens, Paige D Womble, Jacob B Pilcher, Grace O'Neill, Taylor A Wiley, Eliesse M Kwok, Srikhar V Chilukuri, Joaquin N Lug. NS-Pten knockout mice exhibit sex and hippocampal subregion-specific increases in microglia/macrophage density. Epilepsy research. vol 206. 2024-08-30. PMID:39213710. |
seizures induce hippocampal subregion dependent enhancements in microglia/macrophage phagocytosis and cytokine release that may contribute to the development of epilepsy. |
2024-08-30 |
2024-09-04 |
mouse |
| Yuchen Xu, Lily Zhang, Yan Yan, Wenbiao Xiao, Wei Zou, Zhaohui Luo, Bo Xiao, Hongyu Lon. MicroRNA-33 regulates the Synaptic Plasticity-related Gene ARC in Temporal Lobe Epilepsy. Neuroscience research. 2024-08-30. PMID:39214315. |
this study aimed to elucidate the expression patterns of mir-33 and arc in both a rat model of temporal lobe epilepsy (tle) and human tle patients, to explore the role of mir-33 in epilepsy onset through its regulation of arc expression in the hippocampus. |
2024-08-30 |
2024-09-04 |
human |
| M Christianne Hoeberigs, Jan C Beckervordersandforth, G de Bruyn, S Klinkenberg, O E M G Schijn. A teenage girl with drug-resistant epilepsy and a hippocampal angiocentric neuroepithelial tumor (ANET) - illustrative case of 7T MRI in clinical practice. Seizure. vol 121. 2024-08-24. PMID:39181014. |
a teenage girl with drug-resistant epilepsy and a hippocampal angiocentric neuroepithelial tumor (anet) - illustrative case of 7t mri in clinical practice. |
2024-08-24 |
2024-08-28 |
Not clear |
| Adebayo Adeyeye, Sara Mirsadeghi, Maryfer Gutierrez, Jenny Hsie. Integrating adult neurogenesis and human brain organoid models to advance epilepsy and associated behavioral research. Epilepsy & behavior : E&B. vol 159. 2024-08-24. PMID:39181108. |
while in vivo models provide valuable insights into some aspects of epileptogenesis, such as the impact of adult neurogenesis on hippocampal function, brain organoids are indispensable for comprehensively studying epileptogenesis involving genetic mutations that underlie human epilepsy. |
2024-08-24 |
2024-08-28 |
human |
| Lydia Wheeler, Samuel E Worrell, Irena Balzekas, Jordan Bilderbeek, Dora Hermes, Paul Croarkin, Steven Messina, Jamie Van Gompel, Kai J Miller, Vaclav Kremen, Gregory A Worrel. Case report: Bridging limbic network epilepsy with psychiatric, memory, and sleep comorbidities: case illustrations of reversible psychosis symptoms during continuous, high-frequency ANT-DBS. Frontiers in network physiology. vol 4. 2024-08-23. PMID:39175607. |
the network nature of focal epilepsy is exemplified by mesial temporal lobe epilepsy (mtle), characterized by focal seizures originating from the mesial temporal neocortex, amygdala, and hippocampus. |
2024-08-23 |
2024-08-25 |
Not clear |
| Yafu Tan, Yongjia Yu, Haodong Niu, Chunxi Wang, Panlin Mo, Dongqiao Li, Qing Zhang, Daqin Feng, Chang Li. Profile of miRNA expression in the hippocampus of epileptic mice and the prediction of potential therapeutic targets. Molecular biology reports. vol 51. issue 1. 2024-08-22. PMID:39172288. |
in this study, we established a lithium chloride-pilocarpine epilepsy mouse model, performed mirna sequencing of hippocampal tissue samples, and compared the obtained mirna expression profile with that of normal control mice to determine differences in expression levels. |
2024-08-22 |
2024-08-24 |
mouse |
| Maria Giardino, Francesca Peluso, Omar Daolio, Melissa Bellini, Enrico Ambrosini, Matteo Zito, Antonella Squarci. An uncommon neuroradiological finding of hippocampal malrotation in childhood onset schizophrenia and 22q11.2 Deletion Syndrome: a case report and a brief review of the literature. European child & adolescent psychiatry. 2024-08-20. PMID:39164503. |
while abnormalities of white matter and corpus callosum are associated with schizophrenia in patients with 22q11.2 deletion syndrome, hippocampal malrotation is more frequently described in patients with epilepsy and prolonged febrile seizures. |
2024-08-20 |
2024-08-23 |
Not clear |
| Maria Giardino, Francesca Peluso, Omar Daolio, Melissa Bellini, Enrico Ambrosini, Matteo Zito, Antonella Squarci. An uncommon neuroradiological finding of hippocampal malrotation in childhood onset schizophrenia and 22q11.2 Deletion Syndrome: a case report and a brief review of the literature. European child & adolescent psychiatry. 2024-08-20. PMID:39164503. |
recently, only 10 adult patients with 22q11.2 deletion syndrome have been reported to have hippocampal malrotation, six of whom were affected by schizophrenia, with or without epilepsy. |
2024-08-20 |
2024-08-23 |
Not clear |
| Daichi Sone, Iman Beheshti, Yoko Shigemoto, Yukio Kimura, Noriko Sato, Hiroshi Matsud. White matter brain-age in diverse forms of epilepsy and interictal psychosis. Scientific reports. vol 14. issue 1. 2024-08-19. PMID:39160281. |
as a result, almost all epilepsy categories showed significantly increased brain-pad (p < 0.001), including temporal lobe epilepsy (tle) with no mri-lesion (+ 4.2 yr), tle with hippocampal sclerosis (+ 9.1 yr), extratemporal focal epilepsy (+ 5.1 yr), epileptic encephalopathy or progressive myoclonus epilepsy (+ 18.4 yr), except for idiopathic generalized epilepsy (ige). |
2024-08-19 |
2024-08-22 |
human |
| Rhuann Pontes Dos Santos Silva, Isabella Carla Barbosa Lima Angelo, Guilherme Cavalcanti De Medeiros Dantas, Joana Martins De Souza, João Ricardo Caldas Pinheiro Pessoa, Laura Guerra Lopes, João Paulo Mota Telles, Wagner Gonçalves Hort. Pattern of abnormalities on gray matter in patients with medial temporal lobe epilepsy and hippocampal sclerosis: An updated meta-analysis. Clinical neurology and neurosurgery. vol 245. 2024-08-18. PMID:39154538. |
a common pathological feature is hippocampal sclerosis (hs), characterized by the loss of neuronal cells, which is associated with the typical temporal mesial lobe epilepsy (mtle). |
2024-08-18 |
2024-08-21 |
Not clear |
| Jiao Yang, Ji-Heng Cai, Tong-Xuan Wu, Zhi-Qiang Gao, Chao Zhou, Qi Wu, Miao-Jin J. Salvinorin A ameliorates pilocarpine-induced seizures by regulating hippocampal microglia polarization. Journal of ethnopharmacology. 2024-08-18. PMID:39154669. |
considering the anti-inflammatory effect of s. divinorum and endogenous hippocampal dynorphin/ kappa opioid receptor (kor) system playing an anticonvulsant function, we hypothesis that sal a can be a potential candidate to treat epilepsy. |
2024-08-18 |
2024-08-21 |
Not clear |
| Jennifer M Yonan, Kevin D Chen, Tallie Z Baram, Oswald Stewar. PTEN Deletion in the Adult Dentate Gyrus Induces Epilepsy. bioRxiv : the preprint server for biology. 2024-08-16. PMID:39149280. |
pten-deletion provoked epilepsy was not associated with apparent hippocampal neuron death; supra-granular mossy fiber sprouting was observed in a few mice. |
2024-08-16 |
2024-08-18 |
mouse |
| Aileen Harnett, Justine Mathoux, Marc-Michel Wilson, Mona Heiland, Omar Mamad, Sujithra Srinivas, Albert Sanfeliu, Amaya Sanz-Rodriguez, Kelvin Lau E How, Norman Delanty, Jane Cryan, Francesca M Brett, Michael A Farrell, Donncha F O'Brien, David C Henshall, Gary P Brenna. Impact of JQ1 treatment on seizures, hippocampal gene expression, and gliosis in a mouse model of temporal lobe epilepsy. The European journal of neuroscience. 2024-08-16. PMID:39149798. |
despite influencing early aspects of epileptogenesis, blocking bet protein activity with jq1 had no overt effects on epilepsy development in mice but did alter glial reactivity and influence gene expression patterns, promoting various neurotransmitter signalling mechanisms and inflammatory pathways in the hippocampus. |
2024-08-16 |
2024-08-18 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
pvt1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by mir-206-3p-dependent regulation of camk4. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
this study was designed to dissect the function of plasmacytoma variant translocation 1 (pvt1) in hippocampal neuron injury in epilepsy and its possible molecular basis. |
2024-08-14 |
2024-08-16 |
mouse |
| Chuankun Li, Ruichun Li, Xiaobin Bai, Haitao Jian. PVT1 regulates hippocampal neuron apoptosis and inflammation in epilepsy by miR-206-3p-dependent regulation of CAMK4. General physiology and biophysics. vol 43. issue 5. 2024-08-14. PMID:39140685. |
collectively, pvt1 contributed to se-induced apoptosis and inflammation in hippocampal neurons by modulating the mir-206-3p/camk4 axis, offering a novel insight into the prevention of epilepsy. |
2024-08-14 |
2024-08-16 |
mouse |
| Rudhab Bahabry, Rebecca M Hauser, Richard G Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J Stuckey, R Ryley Parrish, Lawrence Ver Hoef, Farah D Lubi. Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy. Neurobiology of disease. 2024-08-14. PMID:39142613. |
alterations in dna 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy. |
2024-08-14 |
2024-08-17 |
human |
| Rudhab Bahabry, Rebecca M Hauser, Richard G Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J Stuckey, R Ryley Parrish, Lawrence Ver Hoef, Farah D Lubi. Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy. Neurobiology of disease. 2024-08-14. PMID:39142613. |
temporal lobe epilepsy (tle) is a type of focal epilepsy characterized by spontaneous recurrent seizures originating from the hippocampus. |
2024-08-14 |
2024-08-17 |
human |
| Gregory Lepeu, Ellen van Maren, Kristina Slabeva, Cecilia Friedrichs-Maeder, Markus Fuchs, Werner J Z'Graggen, Claudio Pollo, Kaspar A Schindler, Antoine Adamantidis, Timothée Proix, Maxime O Bau. The critical dynamics of hippocampal seizures. Nature communications. vol 15. issue 1. 2024-08-13. PMID:39138153. |
here, we verified that predictions on bifurcations applied to the onset of hippocampal seizures, providing concordant results from in silico modeling, optogenetics experiments in male mice and intracranial eeg recordings in human patients with epilepsy. |
2024-08-13 |
2024-08-16 |
human |
| Anton V Chizhov, Vasilii S Tiselko, Tatyana Yu Postnikova, Aleksey V Zaitse. Phase-Dependent Response to Electrical Stimulation of Cortical Networks during Recurrent Epileptiform Short Discharge Generation In Vitro. International journal of molecular sciences. vol 25. issue 15. 2024-08-10. PMID:39125856. |
in this study, we investigated the sensitivity of continuous epileptiform short discharge generation to electrical stimulation applied at different phases between the discharges using an in vitro 4-ap-based model of epilepsy in rat hippocampal slices. |
2024-08-10 |
2024-08-13 |
rat |