| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Chvojka, J Kudláček, K Liska, A Pant, J Gr Jefferys, P Jirusk. Dissociation Between the Epileptogenic Lesion and Primary Seizure Onset Zone in the Tetanus Toxin Model of Temporal Lobe Epilepsy. Physiological research. vol 73. issue 3. 2024-07-19. PMID:39027960. |
epilepsy was induced by injecting a minute dose of tetanus toxin into the right dorsal hippocampus in seven animals. |
2024-07-19 |
2024-07-21 |
Not clear |
| Ankit N Khambhati, Edward F Chang, Maxime O Baud, Vikram R Ra. Hippocampal network activity forecasts epileptic seizures. Nature medicine. 2024-07-12. PMID:38997606. |
in this retrospective cohort study of 15 adults with bitemporal epilepsy who had a device that provides chronic intracranial recordings, functional connectivity of hippocampal networks fluctuated in multiday cycles with patterns that mirrored cycles of seizure likelihood. |
2024-07-12 |
2024-07-15 |
Not clear |
| Donghao Xu, Qingfa Ren, Quanyuan Liu, Miaomiao Liu, He Gong, Yuwei Liu, Zhijie Yin, Zhen Zeng, Shuyuan Xia, Yanyan Zhang, Jie Li, Quansheng Gao, Jing Wang, Xianglin L. Hippocampal Glutamate Levels and Their Correlation With Subregion Volume in School-Aged Children With MRI-Negative Epilepsy: A Preliminary Study. Journal of magnetic resonance imaging : JMRI. 2024-07-06. PMID:38970314. |
hippocampal glutamate levels and their correlation with subregion volume in school-aged children with mri-negative epilepsy: a preliminary study. |
2024-07-06 |
2024-07-12 |
Not clear |
| Yücel Doğruel, Serdar Rahmanov, Abuzer Güngör, Uğur Tür. Selective amygdalohippocampectomy via the paramedian supracerebellar-transtentorial approach for mediobasal temporal epilepsy. Neurosurgical focus: Video. vol 11. issue 1. 2024-07-03. PMID:38957420. |
this video presents the successful treatment of a patient with posterior hippocampal sclerosis and mediobasal temporal epilepsy through the paramedian supracerebellar transtentorial approach. |
2024-07-03 |
2024-07-06 |
Not clear |
| Anne-Marie Neumann, Stefan Britsc. Molecular Genetics of Acquired Temporal Lobe Epilepsy. Biomolecules. vol 14. issue 6. 2024-06-27. PMID:38927072. |
mutations in associated transcription factors may have the potential to innately increase the vulnerability of the hippocampus to develop epilepsy following an injury-an emerging perspective on the epileptogenic process in acquired forms of epilepsy. |
2024-06-27 |
2024-06-29 |
Not clear |
| Roberto Martin Del Campo-Vera, Shivani Sundaram, Richard Lee, Yelim Lee, Andrea Leonor, Ryan S Chung, Arthur Shao, Jonathon Cavaleri, Zachary D Gilbert, Selena Zhang, Alexandra Kammen, Xenos Mason, Christi Heck, Charles Liu, Spencer Kellis, Brian Le. Beta-band power classification of Go/No-go arm reaching responses in the human hippocampus. Journal of neural engineering. 2024-06-24. PMID:38914073. |
our approach centers on capturing the modulation of beta-band (13-30 hz) power from multiple seeg contacts in the hippocampus and minimizing the dimensional complexity of channels and frequency bins.
methods
this study utilizes seeg data from the human hippocampus of 10 participants diagnosed with epilepsy. |
2024-06-24 |
2024-06-27 |
human |
| Anouk M Heuvelmans, Martina Proietti Onori, Monica Frega, Jeffrey D de Hoogen, Eveline Nel, Ype Elgersma, Geeske M van Woerde. Modeling mTORopathy-related epilepsy in cultured murine hippocampal neurons using the multi-electrode array. Experimental neurology. 2024-06-24. PMID:38914275. |
modeling mtoropathy-related epilepsy in cultured murine hippocampal neurons using the multi-electrode array. |
2024-06-24 |
2024-06-27 |
mouse |
| Laura Simões de Oliveira, Heather E O'Leary, Sarfaraz Nawaz, Rita Loureiro, Elizabeth C Davenport, Paul Baxter, Susana R Louros, Owen Dando, Emma Perkins, Julien Peltier, Matthias Trost, Emily K Osterweil, Giles E Hardingham, Michael A Cousin, Sumantra Chattarji, Sam A Booker, Tim A Benke, David J A Wyllie, Peter C Kin. Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder. Molecular autism. vol 15. issue 1. 2024-06-14. PMID:38877552. |
impaired hippocampal function has been implicated in other models of monogenic forms of autism spectrum disorders and id and is often linked to epilepsy and behavioural abnormalities. |
2024-06-14 |
2024-06-17 |
rat |
| Xuefei Zhang, Ting Zhao, Songxue Su, Lei Li, Yubing Zhang, Jiangyu Yan, Xiaoxiao Cui, Yanyan Sun, Jianyuan Zhao, Xiong Han, Jing Ca. An explanation of the role of pyroptosis playing in epilepsy. International immunopharmacology. vol 136. 2024-06-08. PMID:38850794. |
epilepsy is a severe central nervous system disorder characterized by an imbalance between neuronal excitation and inhibition, resulting in heightened neuronal excitability, particularly within the hippocampus. |
2024-06-08 |
2024-06-11 |
Not clear |
| Annika Lehner, Lucas Hoffmann, Stefan Rampp, Roland Coras, Friedrich Paulsen, Renato Frischknecht, Hajo Hamer, Katrin Walther, Sebastian Brandner, Wiebke Hofer, Tom Pieper, Lea-Marie Reisch, Christian G Bien, Ingmar Blumck. Age-dependent increase of perineuronal nets in the human hippocampus and precocious aging in epilepsy. Epilepsia open. 2024-06-07. PMID:38845524. |
age-dependent increase of perineuronal nets in the human hippocampus and precocious aging in epilepsy. |
2024-06-07 |
2024-06-10 |
human |
| Qin Wang, Baijun Qin, Haichun Yu, Yueqiang Hu, Han Yu, Jie Zhong, Jinwen Liu, Chunyuan Yao, Jiawei Zeng, Jingjing Fan, Limei Dia. Advances in circular RNA in the pathogenesis of epilepsy. Neuroscience. 2024-06-06. PMID:38843987. |
this review provides an overview of circrnas considered to be playing regulatory roles in the process of epilepsy and to be involved in multiple biological epilepsy-related processes, such as hippocampal sclerosis, inflammatory response, cell apoptosis, synaptic remodeling, and cell proliferation and differentiation. |
2024-06-06 |
2024-06-10 |
Not clear |
| Tiantian Lu, Xiuling Chen, Qin Zhang, Kun Shang, Xiaogui Yang, Wei Xian. Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies. Neurochemical research. 2024-06-05. PMID:38837094. |
experimental mouse models of epilepsy were established through intraperitoneal injection of pilocarpine, and in vitro injury models of hippocampal neurons were induced by glutamate (glu) stimulation. |
2024-06-05 |
2024-06-07 |
mouse |
| Xuejing Hou, Shanshan Xiao, Xiaohong Xu, Mingze Qin, Xuebing Cheng, Xiangping X. Glycoprotein non-metastatic melanoma protein B (GPNMB) protects against neuroinflammation and neuronal loss in pilocarpine-induced epilepsy via the regulation of microglial polarization. Neuroscience. 2024-05-23. PMID:38782114. |
in conclusion, these results indicated that gpnmb suppressed epilepsy through repression of hippocampal neuroinflammation, suggesting that gpnmb might be considered the potential neurotherapeutic target for epilepsy management and play a protective role against epilepsy by modulating the polarization of microglia. |
2024-05-23 |
2024-05-27 |
rat |
| Takamitsu Iwata, Takufumi Yanagisawa, Yuji Ikegaya, Jonathan Smallwood, Ryohei Fukuma, Satoru Oshino, Naoki Tani, Hui Ming Khoo, Haruhiko Kishim. Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans. Nature communications. vol 15. issue 1. 2024-05-22. PMID:38778048. |
local field potentials were recorded from the hippocampus of 10 patients with epilepsy for up to 15 days, and experience sampling was used to describe their association with ongoing thought patterns. |
2024-05-22 |
2024-05-27 |
human |
| Alyssa B Danis, Ashlynn A Gallagher, Ashley N Anderson, Arielle Isakharov, Kathleen A Beeson, Eric Schnel. Altered Hippocampal Activation in Seizure-Prone eNeuro. vol 11. issue 5. 2024-05-15. PMID:38749701. |
altered hippocampal activation in seizure-prone the voltage-gated calcium channel subunit α2δ-2 controls calcium-dependent signaling in neurons, and loss of this subunit causes epilepsy in both mice and humans. |
2024-05-15 |
2024-05-27 |
mouse |
| Xiang Li, Ning Liu, Di Wu, Shu Chang Li, Qing Wang, Dian-Wen Zhang, Lian-Lian Song, Min Huang, Xia Chen, Wei L. Hippocampal transcriptomic analyses reveal the potential antiapoptotic mechanism of a novel anticonvulsant agent Q808 on pentylenetetrazol-induced epilepsy in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 175. 2024-05-13. PMID:38739991. |
hippocampal transcriptomic analyses reveal the potential antiapoptotic mechanism of a novel anticonvulsant agent q808 on pentylenetetrazol-induced epilepsy in rats. |
2024-05-13 |
2024-05-27 |
rat |
| Ionuț-Flavius Bratu, Samuel Medina Villalon, Elodie Garnier, Christian-G Bénar, Fabrice Bartolome. How fast does the brain recover after an epileptic seizure? Annals of clinical and translational neurology. 2024-05-11. PMID:38730560. |
the average pat was 4.5 min, extending up to an hour and was highest in temporal epilepsy and hippocampal sclerosis. |
2024-05-11 |
2024-05-27 |
Not clear |
| Chang Xiaoyu, Zhou Hongzhen, Peng Nan, Gao Tengwei, Gong Yanan, Guo Yan, La Haiyan, Ma Li, Wu Haiya, Wen Yujun, Zhang Ru. Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy. Frontiers in neurology. vol 15. 2024-05-08. PMID:38715687. |
temporal lobe epilepsy (tle) is a prevalent refractory partial epilepsy seen in clinical practice, with most cases originating from the hippocampus and being characterized by impaired learning and memory. |
2024-05-08 |
2024-05-27 |
mouse |
| Ream Alashjaie, Elizabeth N Kerr, Azhar AlShoumer, Cynthia Hawkins, Ivanna Yau, Shelly Weiss, Ayako Ochi, Hiroshi Otsubo, Pradeep Krishnan, Elysa Widjaja, George M Ibrahim, Elizabeth J Donner, Puneet Jai. Surgical outcomes in children with drug-resistant epilepsy and hippocampal sclerosis. Epilepsy research. vol 203. 2024-05-04. PMID:38703703. |
surgical outcomes in children with drug-resistant epilepsy and hippocampal sclerosis. |
2024-05-04 |
2024-05-07 |
Not clear |
| Ream Alashjaie, Elizabeth N Kerr, Azhar AlShoumer, Cynthia Hawkins, Ivanna Yau, Shelly Weiss, Ayako Ochi, Hiroshi Otsubo, Pradeep Krishnan, Elysa Widjaja, George M Ibrahim, Elizabeth J Donner, Puneet Jai. Surgical outcomes in children with drug-resistant epilepsy and hippocampal sclerosis. Epilepsy research. vol 203. 2024-05-04. PMID:38703703. |
hippocampal sclerosis (hs) is a common surgical substrate in adult epilepsy surgery cohorts but variably reported in various pediatric cohorts. |
2024-05-04 |
2024-05-07 |
Not clear |