| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giacomo Koch, Paolo Porcacchia, Viviana Ponzo, Fatima Carrillo, María Teresa Cáceres-Redondo, Livia Brusa, Maria Teresa Desiato, Flavio Arciprete, Francesco Di Lorenzo, Antonio Pisani, Carlo Caltagirone, Francisco J Palomar, Pablo Mi. Effects of two weeks of cerebellar theta burst stimulation in cervical dystonia patients. Brain stimulation. vol 7. issue 4. 2015-04-13. PMID:24881805. |
dystonia is generally regarded as a disorder of the basal ganglia and their efferent connections to the thalamus and brainstem, but an important role of cerebellar-thalamo-cortical (ctc) circuits in the pathophysiology of dystonia has been invoked. |
2015-04-13 |
2023-08-13 |
Not clear |
| Aileen Ling Wan Tan, Raymond Go. Anaesthetic management of a patient with Leigh's syndrome with central hypoventilation and obstructive sleep apnoea. Singapore medical journal. vol 54. issue 12. 2015-04-06. PMID:24356766. |
her respiratory complications included central hypoventilation secondary to brainstem involvement, and obstructive sleep apnoea due to obesity and muscle dystonia. |
2015-04-06 |
2023-08-12 |
Not clear |
| John C Steele, J Clifford Richardson, Jerzy Olszewsk. Progressive supranuclear palsy: a heterogeneous degeneration involving the brain stem, Basal Ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. Seminars in neurology. vol 34. issue 2. 2015-02-21. PMID:24963673. |
progressive supranuclear palsy: a heterogeneous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. |
2015-02-21 |
2023-08-13 |
Not clear |
| Chihiro Hisatsune, Hiroyuki Miyamoto, Moritoshi Hirono, Naohide Yamaguchi, Takeyuki Sugawara, Naoko Ogawa, Etsuko Ebisui, Toshio Ohshima, Masahisa Yamada, Takao K Hensch, Mitsuharu Hattori, Katsuhiko Mikoshib. IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice. Frontiers in neural circuits. vol 7. 2014-04-08. PMID:24109434. |
here, we found that the conditional knockout mice lacking ip3r1 specifically in the cerebellum and brainstem experience dystonia and show that cerebellar purkinje cell (pc) firing patterns were coupled to specific dystonic movements. |
2014-04-08 |
2023-08-12 |
mouse |
| David G Standaer. Update on the pathology of dystonia. Neurobiology of disease. vol 42. issue 2. 2011-07-11. PMID:21220015. |
in primary dystonias, where dystonia is the main symptom, most reports describe little or no detectable neuropathology, although changes in brainstem neurons have been described in some cases. |
2011-07-11 |
2023-08-12 |
Not clear |
| A Quartarone, V Rizzo, C Terranova, F Morgante, S Schneider, N Ibrahim, P Girlanda, K P Bhatia, J C Rothwel. Abnormal sensorimotor plasticity in organic but not in psychogenic dystonia. Brain : a journal of neurology. vol 132. issue Pt 10. 2010-02-03. PMID:19690095. |
dystonia is characterized by two main pathophysiological abnormalities: 'reduced' excitability of inhibitory systems at many levels of the sensorimotor system, and 'increased' plasticity of neural connections in sensorimotor circuits at a brainstem and spinal level. |
2010-02-03 |
2023-08-12 |
Not clear |
| Michele Tinazzi, Giovanna Squintani, Alfredo Berardell. Does neurophysiological testing provide the information we need to improve the clinical management of primary dystonia? Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 120. issue 8. 2009-08-28. PMID:19616996. |
studies applying various neurophysiological tests, including spinal and brainstem reflexes, transcranial magnetic stimulation, somatosensory evoked potentials and magnetoencephalography, have documented numerous pathophysiological abnormalities in the various forms of primary dystonia. |
2009-08-28 |
2023-08-12 |
Not clear |
| Thomas J Loher, Joachim K Kraus. Dystonia associated with pontomesencephalic lesions. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 2. 2009-06-08. PMID:18951533. |
here, we report on a series of four patients with acquired dystonia following brainstem lesions. |
2009-06-08 |
2023-08-12 |
Not clear |
| Thomas J Loher, Joachim K Kraus. Dystonia associated with pontomesencephalic lesions. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 2. 2009-06-08. PMID:18951533. |
while delayed occurrence of severe brainstem dystonia appears to be rare, it is possible that mild manifestations of dystonia might be ignored or not be emphasized in the presence of other disabling deficits. |
2009-06-08 |
2023-08-12 |
Not clear |
| Dominique Guehl, Emmanuel Cuny, Imad Ghorayeb, Thomas Michelet, Bernard Bioulac, Pierre Burbau. Primate models of dystonia. Progress in neurobiology. vol 87. issue 2. 2009-03-26. PMID:19022333. |
in addition, primate studies revealed that lesions in brain stem areas involved in the control of muscular tone and gabaergic manipulations in various basal ganglia nuclei or thalamus also lead to dystonia. |
2009-03-26 |
2023-08-12 |
human |
| Norman Putzki, Karoline Graf, Philipp Stude, Hans-Christoph Diener, Matthias Maschk. Habituation of the auditory startle response in cervical dystonia and Parkinson's disease. European neurology. vol 59. issue 3-4. 2008-04-03. PMID:18230875. |
in focal dystonia (fd), the excitability of brainstem neurons is abnormally enhanced. |
2008-04-03 |
2023-08-12 |
Not clear |
| J L Holton, S A Schneider, T Ganesharajah, S Gandhi, C Strand, P Shashidharan, J Barreto, N W Wood, A J Lees, K P Bhatia, T Reves. Neuropathology of primary adult-onset dystonia. Neurology. vol 70. issue 9. 2008-03-07. PMID:18299520. |
recently, ubiquitinated perinuclear inclusion bodies were found in the brainstem of patients with dyt1-related dystonia. |
2008-03-07 |
2023-08-12 |
Not clear |
| Stephen Tisch, John C Rothwell, Patricia Limousin, Marwan I Hariz, Daniel M Corco. The physiological effects of pallidal deep brain stimulation in dystonia. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 15. issue 2. 2007-08-01. PMID:17601185. |
physiological and imaging studies in dystonia patients with gpi dbs have demonstrated both short and long-term effects of gpi dbs on motor cortex and subcortical circuits including progressive normalization of spinal and brainstem excitability after gpi dbs which correlate with clinical improvement. |
2007-08-01 |
2023-08-12 |
Not clear |
| Stephen Tisch, John C Rothwell, Patricia Limousin, Marwan I Hariz, Daniel M Corco. The physiological effects of pallidal deep brain stimulation in dystonia. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 15. issue 2. 2007-08-01. PMID:17601185. |
these effects, in light of existing physiological data in dystonia, suggest that gpi dbs acts primarily by major modification of basal ganglia output to brainstem, thalamus, and cortex resulting in neural reorganization, which may explain the characteristic progressive improvement in dystonia after gpi dbs. |
2007-08-01 |
2023-08-12 |
Not clear |
| Jörg Müller, Martina Rinnerthaler, Werner Poewe, Markus Kofle. Auditory startle reaction in primary blepharospasm. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 2. 2007-03-23. PMID:17149731. |
primary dystonia is associated with abnormal brainstem function, as shown by abnormalities of the blink reflex in blepharospasm (bsp) and of the auditory startle reaction in cervical dystonia. |
2007-03-23 |
2023-08-12 |
human |
| Jörg Müller, Martina Rinnerthaler, Werner Poewe, Markus Kofle. Auditory startle reaction in primary blepharospasm. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 2. 2007-03-23. PMID:17149731. |
we examined the auditory startle reaction--a brainstem reflex elicited by an unexpected loud stimulus--in patients with primary bsp to expand knowledge on brainstem pathophysiology in primary focal dystonia. |
2007-03-23 |
2023-08-12 |
human |
| Jörg Müller, Martina Rinnerthaler, Werner Poewe, Markus Kofle. Auditory startle reaction in primary blepharospasm. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 2. 2007-03-23. PMID:17149731. |
these results corroborate previous findings of increased brainstem excitability in primary bsp but point to a different pattern of brainstem dysfunction compared to cervical dystonia, indicating that different pathophysiological mechanisms are involved in the two types of focal dystonia. |
2007-03-23 |
2023-08-12 |
human |
| Kevin St P McNaught, Alexander Kapustin, Tehone Jackson, Toni-Ann Jengelley, Ruth Jnobaptiste, Pullanipally Shashidharan, Daniel P Perl, Pedro Pasik, C Warren Olano. Brainstem pathology in DYT1 primary torsion dystonia. Annals of neurology. vol 56. issue 4. 2004-12-02. PMID:15455404. |
brainstem pathology in dyt1 primary torsion dystonia. |
2004-12-02 |
2023-08-12 |
Not clear |
| Kevin St P McNaught, Alexander Kapustin, Tehone Jackson, Toni-Ann Jengelley, Ruth Jnobaptiste, Pullanipally Shashidharan, Daniel P Perl, Pedro Pasik, C Warren Olano. Brainstem pathology in DYT1 primary torsion dystonia. Annals of neurology. vol 56. issue 4. 2004-12-02. PMID:15455404. |
the role of the pedunculopontine and cuneiform nuclei, and related brainstem brainstem structures, in mediating motor activity and controlling muscle tone suggests that alterations in these structures could underlie the pathophysiology of dyt1 dystonia [corrected] |
2004-12-02 |
2023-08-12 |
Not clear |
| Masaya Segaw. [Visual child neurology]. Rinsho shinkeigaku = Clinical neurology. vol 43. issue 11. 2004-08-13. PMID:15152453. |
here, i reviewed the characteristic symptoms and their pathophysiologies of rett syndrome, dyt-1, autosomal dominant gtp cyclohydrolase i (adgch i) deficiency, tourette syndrome (ts) and early-onset ataxia with ocular motor apraxia and hypoalbuminemia (eaoh), and suggested that the brainstem aminergic neurons modulating the locomotion have roles for development of the frontal cortex, the dopaminergic neurons and basal ganglia pathways involving in the action dystonia for motor execution and the serotonergic and the dopaminergic neurons projectioning to the nonmotor basal ganglia thalamocortical circuits for development of the frontal area, the targets of the circuits. |
2004-08-13 |
2023-08-12 |
Not clear |