| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue Gao, Yujuan Hong, Lihong Huang, Shuang Zheng, Haibin Zhang, Shihua Wang, Yi Yao, Yini Zhao, Lin Zhu, Qiang Xu, Xuhui Chai, Yuanyuan Zeng, Yuzhe Zeng, Liangkai Zheng, Yulin Zhou, Hong Luo, Xian Zhang, Hongfeng Zhang, Ying Zhou, Guo Fu, Hao Sun, Timothy Y Huang, Qiuyang Zheng, Huaxi Xu, Xin Wan. β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function. Cell. vol 186. issue 5. 2023-03-03. PMID:36868208. |
down syndrome (ds) is a neurological disorder with multiple immune-related symptoms; however, crosstalk between the cns and peripheral immune system remains unexplored. |
2023-03-03 |
2023-08-14 |
mouse |
| Noemi A Spinazzi, Jonathan D Santoro, Katherine Pawlowski, Gabriel Anzueto, Yamini J Howe, Lina R Patel, Nicole T Baume. Co-occurring conditions in children with Down syndrome and autism: a retrospective study. Journal of neurodevelopmental disorders. vol 15. issue 1. 2023-03-02. PMID:36864370. |
down syndrome (ds) is one of the most common genetic causes of intellectual disability, and it is associated with an increased incidence of numerous co-occurring conditions. |
2023-03-02 |
2023-08-14 |
Not clear |
| Pelin Atalan Efkere, Tülay Tarsusl. The effects of Kinesio taping on static and dynamic balance in children with down syndrome: a randomized controlled trial. Somatosensory & motor research. 2023-02-28. PMID:36852775. |
this study aimed to determine the effects of kinesio tape applied to the plantar soles on static and dynamic balance in children with down syndrome (ds). |
2023-02-28 |
2023-08-14 |
Not clear |
| L Agostini, L Mezzofranco, A Gracco, A De Stefani, G Brun. Analysis of sleep and symptoms related to OSAS in a group of paediatric patients with Down syndrome. European journal of paediatric dentistry. vol 24. issue 1. 2023-02-28. PMID:36853209. |
children with down syndrome (ds) are more likely to have obstructive sleep apnoea, due to their craniofacial characteristics. |
2023-02-28 |
2023-08-14 |
Not clear |
| Haneesha Movva, Karuna Taksand. Anesthetic Management of a Down Syndrome Patient for Ventricular Septal Defect Repair: A Case Report. Cureus. vol 15. issue 1. 2023-02-27. PMID:36843750. |
it is commonly known that down syndrome (ds) and congenital cardiovascular abnormalities go hand in hand. |
2023-02-27 |
2023-08-14 |
Not clear |
| Xueyu Hou, Na Wu, Shimeng Ren, Xinjuan Wang, Qing Mu, Yang Zhang, Shan Wang, Weidong Yu, Jingzhu Gu. Profiling Frontiers in cellular and infection microbiology. vol 13. 2023-02-27. PMID:36844413. |
profiling down syndrome (ds), the presence of a supernumerary chromosome 21, is associated with cognitive dysfunction caused by early neurodegenerative processes. |
2023-02-27 |
2023-08-14 |
Not clear |
| Luiza Torres-Nunes, Patrícia Prado da Costa-Borges, Laisa Liane Paineiras-Domingos, José Alexandre Bachur, Ana Carolina Coelho-Oliveira, Danúbia da Cunha de Sá-Caputo, Mario Bernardo-Filh. Effects of the Whole-Body Vibration Exercise on Sleep Disorders, Body Temperature, Body Composition, Tone, and Clinical Parameters in a Child with Down Syndrome Who Underwent Total Atrioventricular Septal Defect Surgery: A Case-Report. Children (Basel, Switzerland). vol 10. issue 2. 2023-02-25. PMID:36832342. |
the health and developmental issues of people with down syndrome (ds) are complex and are associated with many medical, psychological, and social problems from childhood through into adulthood. |
2023-02-25 |
2023-08-14 |
Not clear |
| Natalie Baker Campbell, Yesha Patel, Tara L Moore, Maria Medalla, Ella Zeldic. Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36834891. |
down syndrome (ds), or trisomy 21, is manifested in a variety of anatomical and cellular abnormalities resulting in intellectual deficits and early onset of alzheimer's disease (ad) with no effective treatments available to alleviate the pathologies associated with the disorder. |
2023-02-25 |
2023-08-14 |
human |
| Shaji Thomas John, Kizhanipurath Gayathri, Shabina Ahmed, Kawaljit Singh Multtani, Puthezhath Shankar Narayanan Menon, Raman Krishna Kumar, Vaikom Hariharan Sankar, Prajnya Ranganath, Neerja Gupta, Mohandas Nair, Madhava Vijayakumar, Jeeson C Unn. Consensus Statement of the Neurodevelopmental Pediatrics Chapter of Indian Academy of Pediatrics (IAP) on the Management of Children With Down Syndrome. Indian pediatrics. 2023-02-23. PMID:36814128. |
the diagnosis of down syndrome (ds) is easily made clinically but the management is multi-disciplinary and life-long. |
2023-02-23 |
2023-08-14 |
Not clear |
| Muhammad Faizi, Nur Rochmah, Soetjipto Soetjipto, Anang Endaryanto, Sukmawati Basuki, Yuni Hisbiyah, Rayi Kurnia Perwitasar. Protein tyrosine phosphatase non-receptor type 22 C1858T gene polymorphism in children with down syndrome and autoimmune thyroid diseases. La Pediatria medica e chirurgica : Medical and surgical pediatrics. vol 45. issue 1. 2023-02-23. PMID:36815569. |
autoimmune thyroid disease (ait) is a frequent comorbidity in down syndrome (ds). |
2023-02-23 |
2023-08-14 |
human |
| Jan T Czerminski, Oliver D King, Jeanne B Lawrenc. Large-scale organoid study suggests effects of trisomy 21 on early fetal neurodevelopment are more subtle than variability between isogenic lines and experiments. Frontiers in neuroscience. vol 16. 2023-02-23. PMID:36817096. |
this study examines cortical organoids generated from a panel of isogenic trisomic and disomic ipsc lines (subclones) as a model of early fetal brain development in down syndrome (ds). |
2023-02-23 |
2023-08-14 |
Not clear |
| Sian L Grace, Georgina L Mortimer, Aizhan Kozhakhmetova, Jamie Leveret, Richard Newton, Koit Reimand, Julian P H Shield, Raivo Uibo, Alistair J K Williams, Kathleen M Gillespi. Increased levels of anti-BSA antibodies in children with Down syndrome. Frontiers in endocrinology. vol 14. 2023-02-23. PMID:36817608. |
autoimmune diabetes occurs more often in the first 2 years of life in children with down syndrome (ds) compared with the general population. |
2023-02-23 |
2023-08-14 |
Not clear |
| Arzu Etem Akagac, Hatice Bozkurt Yavu. Fibrin clot interference in a human chorionic gonadotrophin assay causing a false Down syndrome screening result. Biochemia medica. vol 33. issue 1. 2023-02-23. PMID:36817855. |
lower hcg concentrations correlate with a lower calculated risk of down syndrome (ds). |
2023-02-23 |
2023-08-14 |
human |
| Phillip M Muza, Daniel Bush, Marta Pérez-González, Ines Zouhair, Karen Cleverley, Miriam L Sopena, Rifdat Aoidi, Steven J West, Mark Good, Victor L J Tybulewicz, Matthew C Walker, Elizabeth M C Fisher, Pishan Chan. Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. iScience. vol 26. issue 2. 2023-02-23. PMID:36818290. |
the dp(10)2yey mouse carries a ∼2.3-mb intra-chromosomal duplication of mouse chromosome 10 (mmu10) that has homology to human chromosome 21, making it an essential model for aspects of down syndrome (ds, trisomy 21). |
2023-02-23 |
2023-08-14 |
mouse |
| Lauren T Ptomey, Nicolas M Oreskovic, James A Hendrix, Dominica Nichols, Stamatis Agiovlasiti. Weight management recommendations for youth with Down syndrome: Expert recommendations. Frontiers in pediatrics. vol 10. 2023-02-23. PMID:36819200. |
youth with down syndrome (ds) have a higher prevalence of overweight and obesity compared to the general youth population. |
2023-02-23 |
2023-08-14 |
Not clear |
| Eman G Abdelrahman, Naglaa M Kamal, Sultan Alharthi, Muflih Albalawi, Effat Assa. Down syndrome patients with normal hearts: are they really normal? Medicine. vol 102. issue 6. 2023-02-23. PMID:36820596. |
even though congenital heart disease is a common finding in down syndrome (ds) patients, some of them have anatomically normal hearts. |
2023-02-23 |
2023-08-14 |
Not clear |
| Yoko Kanbara, Chisen Takeuchi, Yoko Mochizuki, Miho Osako, Motoko Sasaki, Hidehiko Miyak. Medical needs of adults with Down syndrome in a regional medical and rehabilitation center in Japan. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2023-02-23. PMID:36823125. |
background down syndrome (ds) is the most frequent chromosomal condition; however, knowledge about associated health issues in adulthood is inadequate. |
2023-02-23 |
2023-08-14 |
Not clear |
| María Galán-Olleros, Ángel Palazón-Quevedo, Rosa M Egea-Gámez, Ana Ramírez-Barragán, J Ignacio Serrano, Ignacio Martínez-Caballer. Is There a Relationship Between the Functional Level of Juvenile and Adolescent Patients With Down Syndrome and Hip Dysplasia? Journal of pediatric orthopedics. 2023-02-22. PMID:36804878. |
the prevalence of hip dysplasia among patients with down syndrome (ds) is higher than in the general population. |
2023-02-22 |
2023-08-14 |
Not clear |
| Arwas Noga, Goldbart Aviv, Aviram Micha, Dizitzer Yotam, Pansky Itay, Golan-Tripto Inba. Flexible bronchoscopy in pediatric patients with Down syndrome: a case-control study of the indications, findings, and complications. Pediatric pulmonology. 2023-02-22. PMID:36811243. |
children with down syndrome (ds) often undergo flexible bronchoscopies (fb) due to common respiratory symptoms. |
2023-02-22 |
2023-08-14 |
Not clear |
| Laura Xicota, Julien Lagarde, Fanny Eysert, Benjamin Grenier-Boley, Isabelle Rivals, Alexandra Botté, Sylvie Forlani, Sophie Landron, Clément Gautier, Cecilia Gabriel, Michel Bottlaender, Jean-Charles Lambert, Mounia Chami, Marie Sarazin, Marie-Claude Potie. Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer's disease patients are associated with cognitive impairment. Translational psychiatry. vol 13. issue 1. 2023-02-14. PMID:36788216. |
morphological alterations of the endosomal compartment have been widely described in post-mortem brains from alzheimer's disease (ad) patients and subjects with down syndrome (ds) who are at high risk for ad. |
2023-02-14 |
2023-08-14 |
human |