| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ze Zhang, Hannah G Stolrow, Brock C Christensen, Lucas A Sala. Down Syndrome Altered Cell Composition in Blood, Brain, and Buccal Swab Samples Profiled by DNA-Methylation-Based Cell-Type Deconvolution. Cells. vol 12. issue 8. 2023-05-16. PMID:37190077. |
down syndrome (ds) is a genetic disorder caused by an extra copy of chromosome 21 that presents developmental dysfunction and intellectual disability. |
2023-05-16 |
2023-08-14 |
human |
| Melissa J Alldred, Harshitha Pidikiti, Adriana Heguy, Panos Roussos, Stephen D Ginsber. Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 6. 2023-05-16. PMID:37191946. |
basal forebrain cholinergic neuron (bfcn) degeneration is a hallmark of down syndrome (ds) and alzheimer's disease (ad). |
2023-05-16 |
2023-08-14 |
mouse |
| Stephanie L Santoro, Kelsey Haugen, Karen Donelan, Brian G Skotk. Global health measures from a National Down Syndrome Registry. American journal of medical genetics. Part A. 2023-05-15. PMID:37183579. |
people with down syndrome (ds) have a unique medical profile which may impact views of health. |
2023-05-15 |
2023-08-14 |
Not clear |
| Fernanda Salgado, Guillermo Larios, Gonzalo Valenzuela, Rodolfo Amstein, Patricio Valle, Paulo Valderram. Extubation failure after cardiac surgery in children with Down syndrome. European journal of pediatrics. 2023-05-15. PMID:37186033. |
approximately 50% of children with down syndrome (ds) have congenital heart disease. |
2023-05-15 |
2023-08-14 |
Not clear |
| Yelda Kaya, Seda Saka, Deniz Tunce. Effect of hippotherapy on balance, functional mobility, and functional independence in children with Down syndrome: randomized controlled trial. European journal of pediatrics. 2023-05-15. PMID:37186034. |
impaired muscle strength, proprioceptive and vestibular deficits, and orthopedic dysfunction are common disorders associated with down syndrome (ds). |
2023-05-15 |
2023-08-14 |
Not clear |
| William Rojas-Carabali, María Camila Cortés-Albornoz, Gabriela Flórez-Esparza, Carlos Cifuentes-González, Alejandra de-la-Torre, Claudia Talero-Gutiérre. Ophthalmic manifestations in children with Down Syndrome in Bogotá, Colombia. BMC ophthalmology. vol 23. issue 1. 2023-05-15. PMID:37189079. |
to describe the ocular features of a cohort of children with down syndrome (ds) in bogotá, colombia. |
2023-05-15 |
2023-08-14 |
Not clear |
| Ann-Charlotte Granhol. Long-Term Effects of SARS-CoV-2 in the Brain: Clinical Consequences and Molecular Mechanisms. Journal of clinical medicine. vol 12. issue 9. 2023-05-14. PMID:37176630. |
individuals with alzheimer's disease (ad) and related dementia, as well as persons with down syndrome (ds), are especially vulnerable to covid-19, but the biological reasons for this are not clear. |
2023-05-14 |
2023-08-14 |
Not clear |
| Fang Cai, Beibei Song, Yi Yang, Haikang Liao, Ran Li, Zhao Wang, Ruixue Cao, Huaqiu Chen, Juelu Wang, Yili Wu, Yun Zhang, Weihong Son. USP25 contributes to defective neurogenesis and cognitive impairments. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 6. 2023-05-12. PMID:37171286. |
both down syndrome (ds) individuals and animal models exhibit hypo-cellularity in hippocampus and neocortex indicated by enhanced neuronal death and compromised neurogenesis. |
2023-05-12 |
2023-08-14 |
mouse |
| David Shaki, Eli Hershkovitz, Shai Tamam, Arkadi Bollotin, Odeya David, Guy Yalovitsky, Neta Loewenthal, Lior Carmon, Dganit Walker, Raphael Nowak, Alon Hai. GH treatment in pediatric Down syndrome: a systematic review and mini meta-analysis. Frontiers in endocrinology. vol 14. 2023-05-08. PMID:37152958. |
to analyze and determine the safety and efficacy of growth hormone (gh) treatment in down syndrome (ds) pediatric patients and to weigh ethical aspects involved. |
2023-05-08 |
2023-08-14 |
Not clear |
| Daphna Landau Prat, Christiana E Munroe, Karen Revere, Lama Khatib, Peiying Hua, Gui-Shuang Ying, Gil Binenbaum, James A Katowitz, William R Katowit. Outcome of Primary Monocanalicular Stent Placement in Pediatric Down Syndrome Patients with Congenital Nasolacrimal Obstruction. Ophthalmic plastic and reconstructive surgery. 2023-05-03. PMID:37133389. |
congenital nasolacrimal duct obstruction (cnldo) is a relatively common problem in children with down syndrome (ds). |
2023-05-03 |
2023-08-14 |
Not clear |
| Patricia West, Emily J Jensen, Sarah N Douglas, Gwen Wyatt, Lorraine Robbins, Charles Give. Perceptions of families with adolescents utilizing augmentative and alternative communication technology: A qualitative approach. Journal of pediatric nursing. 2023-05-01. PMID:37127476. |
the aim of this qualitative study was to explore parent-reported factors contributing to family adaptation among families with adolescents diagnosed with autism and/or down syndrome (ds) utilizing aac technology. |
2023-05-01 |
2023-08-14 |
Not clear |
| Albert M Isaacs, Ashruta Narapareddy, Andrew Nam, Kasey Hutcheson, Michelle Stone, Christopher M Bonfiel. Surgical treatment of craniovertebral junction instability in children with Down syndrome: a systematic review. Journal of neurosurgery. Pediatrics. 2023-04-29. PMID:37119098. |
down syndrome (ds) affects 1 in 700 live births and approximately one-third of patients develop craniovertebral junction (cvj) instability, diagnosed by clinical examination and radiological measures such as the atlantodens interval (adi) and space available for the cord (sac). |
2023-04-29 |
2023-08-14 |
Not clear |
| Kwadwo Fosu, Jude Tetteh Quarshie, Kwabena Amofa Nketia Sarpong, Anastasia Rosebud Aikin. Inverse Comorbidity between Down Syndrome and Solid Tumors: Insights from In Silico Analyses of Down Syndrome Critical Region Genes. Genes. vol 14. issue 4. 2023-04-28. PMID:37107558. |
an inverse comorbidity has been observed between down syndrome (ds) and solid tumors such as breast and lung cancers, and it is posited that the overexpression of genes within the down syndrome critical region (dscr) of human chromosome 21 may account for this phenomenon. |
2023-04-28 |
2023-08-14 |
mouse |
| Birger Tielemans, Lander De Herdt, Emilie Pollenus, Emiel Vanhulle, Laura Seldeslachts, Fopke Marain, Flore Belmans, Kaveh Ahookhosh, Jeroen Vanoirbeek, Kurt Vermeire, Philippe E Van den Steen, Greetje Vande Veld. A Multimodal Imaging-Supported Down Syndrome Mouse Model of RSV Infection. Viruses. vol 15. issue 4. 2023-04-28. PMID:37112973. |
individuals with down syndrome (ds) are more prone to develop severe respiratory tract infections. |
2023-04-28 |
2023-08-14 |
mouse |
| Shuji Ishida, Hidehiko Nakanishi, Yukako Kosaka, Ayano Yamaguchi, Mari Ook. Evaluation of newborns with Down syndrome with weight less than 1500 g in the neonatal intensive care unit: A Japanese multicentre study. Journal of paediatrics and child health. 2023-04-28. PMID:37114469. |
this study aimed to clarify the characteristics and their mortality-related factors in very low birthweight infants with down syndrome (ds) in japan. |
2023-04-28 |
2023-08-14 |
Not clear |
| Farah Mgaieth, R Asaad Baksh, Carla M Startin, Sarah Hamburg, Rosalyn Hithersay, Sarah Pape, Henrik Zetterberg, Nicholas J Ashton, Miren Tamayo-Elizalde, Fedal Saini, Mina Idris, The LonDownS Consortium, Andre Strydo. Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-04-28. PMID:37114906. |
adults with down syndrome (ds) are at ultra-high risk of developing alzheimer's disease (ad), characterized by poor episodic memory and semantic fluency in the preclinical phase in the general population. |
2023-04-28 |
2023-08-14 |
Not clear |
| Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewic. Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England). vol 150. issue 8. 2023-04-27. PMID:37102702. |
down syndrome (ds), trisomy of human chromosome 21 (hsa21), occurs in 1 in 800 live births and is the most common human aneuploidy. |
2023-04-27 |
2023-08-14 |
mouse |
| Amanallah Soltani, Emily K Schworer, Raouf Amin, Emily K Hoffman, Anna J Esbense. Executive Functioning, Language, and Behavioral Abilities Related to Obstructive Sleep Apnea in Down Syndrome. Journal of developmental and behavioral pediatrics : JDBP. 2023-04-26. PMID:37099648. |
obstructive sleep apnea (osa) is highly prevalent among individuals with down syndrome (ds), and the nonphysiological consequences of osa require examination to inform treatment planning. |
2023-04-26 |
2023-08-14 |
Not clear |
| Anil Kumar Bhalla, Harvinder Kaur, Rupinder Kaur, Inusha Panigrahi, Brij Nandan Singh Wali. Growth Pattern and Use of Inter-pupillary Distance in the Detection of Ocular Hypertelorism and Hypotelorism in Indian Down Syndrome Children. Journal of pediatric genetics. vol 12. issue 2. 2023-04-24. PMID:37090836. |
in view of complete absence of serial data on growth of ipd, this study aims to unfold auxological dynamics of ipd in down syndrome (ds) children of indian origin. |
2023-04-24 |
2023-08-14 |
Not clear |
| Noémie Treichel, Daniel Dukes, Ben Meuleman, Jo Van Herwegen, Andrea C Samso. "Not in the mood": The fear of being laughed at is better predicted by humor temperament traits than diagnosis in neurodevelopmental conditions. Research in developmental disabilities. vol 137. 2023-04-24. PMID:37094391. |
the goals of the present study were to discover whether the high levels of gelotophobia found in autism in previous studies were replicated here, to expand the research to down syndrome (ds) and williams syndrome (ws), and to assess the relation between individual differences and social impairments, affective predispositions, and humor temperament. |
2023-04-24 |
2023-08-14 |
Not clear |