| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Torayuki Okuyama, Junko Yotsumoto, Yumi Funat. Survey of second-trimester maternal serum screening in Japan. The journal of obstetrics and gynaecology research. vol 39. issue 5. 2013-12-11. PMID:23509876. |
we hypothesize that patient education and physician knowledge of down syndrome (ds) screening are insufficient to provide adequate information regarding prenatal screening in japan. |
2013-12-11 |
2023-08-12 |
Not clear |
| Yonata Levy, Ariela Eila. Pathways to language: a naturalistic study of children with Williams syndrome and children with Down syndrome. Journal of child language. vol 40. issue 1. 2013-12-10. PMID:23217293. |
this is a naturalistic study of the development of language in hebrew-speaking children with williams syndrome (ws) and children with down syndrome (ds), whose mlu extended from 1·0 to 4·4. |
2013-12-10 |
2023-08-12 |
Not clear |
| Lizbeth H Finestack, Audra M Sterling, Leonard Abbedut. Discriminating Down Syndrome and Fragile X syndrome based on language ability. Journal of child language. vol 40. issue 1. 2013-12-10. PMID:23217297. |
abstract this study compared the receptive and expressive language profiles of verbally expressive children and adolescents with down syndrome (ds) and those with fragile x syndrome (fxs) and examined the extent to which these profiles reliably differentiate the diagnostic groups. |
2013-12-10 |
2023-08-12 |
human |
| David S Stein, Kerim M Munir, Andrea J Karweck, Emily J Davidson, Martin T Stei. Developmental regression, depression, and psychosocial stress in an adolescent with Down syndrome. Journal of developmental and behavioral pediatrics : JDBP. vol 34. issue 3. 2013-12-09. PMID:23572173. |
kristen is a 13-year-old girl with down syndrome (ds) who was seen urgently with concerns of cognitive and developmental regression including loss of language, social, and toileting skills. |
2013-12-09 |
2023-08-12 |
Not clear |
| Thai Hoa Tran, David Mitchell, David Dix, Sonia Cellot, Marie-Chantal Ethier, Biljana Gillmeister, Johann Hitzler, Victor Lewis, Rochelle Yanofsky, Donna L Johnston, Carol Portwine, Victoria Price, Shayna Zelcer, Mariana Silva, Bruno Michon, Lynette Bowes, Kent Stobart, Josee Brossard, Joseph Beyene, Lillian Sun. Infections in children with down syndrome and acute myeloid leukemia: a report from the Canadian infections in AML research group. Infectious agents and cancer. vol 8. issue 1. 2013-12-09. PMID:24289042. |
children with down syndrome (ds) are at high risk of infectious toxicity when treated with acute lymphoblastic leukemia chemotherapy protocols optimized in children without ds. |
2013-12-09 |
2023-08-12 |
Not clear |
| Emre Yanikkerem, Semra Ay, Alev Y Ciftçi, Sema Ustgorul, Asli Goke. A survey of the awareness, use and attitudes of women towards Down syndrome screening. Journal of clinical nursing. vol 22. issue 11-12. 2013-12-06. PMID:23030317. |
to determine awareness, use and attitudes of turkish women towards prenatal screening tests (pst) for down syndrome (ds). |
2013-12-06 |
2023-08-12 |
Not clear |
| Jia-Yun Chen, Jia-Ren Lin, Feng-Chiao Tsai, Tobias Meye. Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle. Molecular cell. vol 52. issue 1. 2013-12-06. PMID:24119401. |
one exception is down syndrome (ds), where a third copy of chromosome 21 mediates neurogenesis defects and lowers the frequency of solid tumors. |
2013-12-06 |
2023-08-12 |
Not clear |
| Massimiliano Pau, Manuela Galli, Marcello Crivellini, Giorgio Albertin. Relationship between obesity and plantar pressure distribution in youths with Down syndrome. American journal of physical medicine & rehabilitation. vol 92. issue 10. 2013-12-03. PMID:23636082. |
this study aimed to characterize the effect of obesity on foot-ground contact in young individuals affected by down syndrome (ds) during quiet upright stance. |
2013-12-03 |
2023-08-12 |
Not clear |
| Rachel J Aitken, Kay L Mehers, Alistair J Williams, Jamie Brown, Polly J Bingley, Reinhard W Holl, Tilman R Rohrer, Edith Schober, Majedah M Abdul-Rasoul, Julian P H Shield, Kathleen M Gillespi. Early-onset, coexisting autoimmunity and decreased HLA-mediated susceptibility are the characteristics of diabetes in Down syndrome. Diabetes care. vol 36. issue 5. 2013-12-02. PMID:23275362. |
down syndrome (ds) is associated with an increased risk of diabetes, particularly in young children. |
2013-12-02 |
2023-08-12 |
Not clear |
| Stefania Trazzi, Claudia Fuchs, Emanuele Valli, Giovanni Perini, Renata Bartesaghi, Elisabetta Cian. The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome. The Journal of biological chemistry. vol 288. issue 29. 2013-11-29. PMID:23740250. |
intellectual disability in down syndrome (ds) appears to be related to severe proliferation impairment during brain development. |
2013-11-29 |
2023-08-12 |
mouse |
| Yong Xu, Wuxian Li, Xueyan Liu, Hong Chen, Kuibi Tan, Yuyu Chen, Zhiguang Tu, Yong Da. Identification of dysregulated microRNAs in lymphocytes from children with Down syndrome. Gene. vol 530. issue 2. 2013-11-29. PMID:23933415. |
given the important roles of mirnas in post-transcriptional regulation and its implications for the development of immune tissues and cells, characterization of mirnas promotes us to uncover the molecular mechanisms underlying the pathway of trisomic chromosome 21 that disrupts the disomic genes expression and immunological defects related to down syndrome (ds). |
2013-11-29 |
2023-08-12 |
human |
| Nicolas Gutierrez-Castellanos, Beerend H J Winkelman, Leonardo Tolosa-Rodriguez, Benjamin Devenney, Roger H Reeves, Chris I De Zeeu. Size does not always matter: Ts65Dn Down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal SAG treatment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 39. 2013-11-25. PMID:24068809. |
humans with down syndrome (ds) and ts65dn mice both show a reduced volume of the cerebellum due to a significant reduction in the density of granule neurons. |
2013-11-25 |
2023-08-12 |
mouse |
| Andrea Corrales, Paula Martínez, Susana García, Verónica Vidal, Eva García, Jesús Flórez, Emilio J Sanchez-Barceló, Carmen Martínez-Cué, Noemí Rued. Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome. Journal of pineal research. vol 54. issue 3. 2013-11-19. PMID:23350971. |
ts65dn mice (ts), the most commonly used model of down syndrome (ds), exhibit phenotypic characteristics of this condition. |
2013-11-19 |
2023-08-12 |
mouse |
| Shao-Shuai Wang, Ling Feng, Fu-Yuan Qiao, Juan-Juan L. Functional variant in methionine synthase reductase decreases the risk of Down syndrome in China. The journal of obstetrics and gynaecology research. vol 39. issue 2. 2013-11-18. PMID:22925068. |
down syndrome (ds) is the most common genetic cause of human mental retardation and the genes involved in homocysteine/folate metabolism may play important roles in this condition. |
2013-11-18 |
2023-08-12 |
human |
| Andre Strydom, Trevor Chan, Michael King, Angela Hassiotis, Gill Livingsto. Incidence of dementia in older adults with intellectual disabilities. Research in developmental disabilities. vol 34. issue 6. 2013-11-18. PMID:23578903. |
the increased risk for alzheimer's disease in people with down syndrome (ds) is well established, but much less is known about dementia in adults with id who do not have ds. |
2013-11-18 |
2023-08-12 |
human |
| Ana Carolina de Campos, Carolina Souza Neves da Costa, Geert J P Savelsbergh, Nelci Adriana Cicuto Ferreira Roch. Infants with Down syndrome and their interactions with objects: development of exploratory actions after reaching onset. Research in developmental disabilities. vol 34. issue 6. 2013-11-18. PMID:23584171. |
we assessed the development of exploratory actions in 16 typically-developing (td) infants and 9 infants with down syndrome (ds) after reaching onset. |
2013-11-18 |
2023-08-12 |
Not clear |
| Sébastien Malinge, Tim Chlon, Louis C Doré, Rhett P Ketterling, Martin S Tallman, Elisabeth Paietta, Alan S Gamis, Jeffrey W Taub, Stella T Chou, Mitchell J Weiss, John D Crispino, Maria E Figuero. Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes. Blood. vol 122. issue 14. 2013-11-18. PMID:23980066. |
acute megakaryoblastic leukemia (amkl) is more frequently observed in down syndrome (ds) patients, in whom it is often preceded by a transient myeloproliferative disorder (tmd). |
2013-11-18 |
2023-08-12 |
Not clear |
| Md Mahiuddin Ahmed, A Ranjitha Dhanasekaran, Suhong Tong, Frances K Wiseman, Elizabeth M C Fisher, Victor L J Tybulewicz, Katheleen J Gardine. Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Human molecular genetics. vol 22. issue 9. 2013-11-14. PMID:23349361. |
tc1 mouse model of down syndrome (ds) is functionally trisomic for ∼120 human chromosome 21 (hsa21) classical protein-coding genes. |
2013-11-14 |
2023-08-12 |
mouse |
| Lixue Guan, Cuiai Ren, Haibo Li, Li Gao, Nan Jia, Hui Gua. [Practicality of rapid prenatal screening for Down syndrome with PCR-short tandem repeat method]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 30. issue 3. 2013-11-14. PMID:23744314. |
to assess the practicality of rapid prenatal screening for down syndrome (ds) by polymerase chain reaction-short tandem repeat (pcr-str) method, and to determine the genotypes of 7 str loci in ethnic chinese han from weifang region. |
2013-11-14 |
2023-08-12 |
Not clear |
| Fiorenza Stagni, Jacopo Magistretti, Sandra Guidi, Elisabetta Ciani, Chiara Mangano, Laura Calzà, Renata Bartesagh. Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome. PloS one. vol 8. issue 4. 2013-11-11. PMID:23620781. |
down syndrome (ds) is a high-incidence genetic pathology characterized by severe impairment of cognitive functions, including declarative memory. |
2013-11-11 |
2023-08-12 |
mouse |