| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tomoko Komatsu, Yoon Duckyoung, Ayumi Ito, Kenji Kurosawa, Yojiro Maehata, Tomoko Kubodera, Masakazu Ikeda, Masaichi-Chang-il Le. Increased oxidative stress biomarkers in the saliva of Down syndrome patients. Archives of oral biology. vol 58. issue 9. 2014-04-22. PMID:23714170. |
we previously reported that the generation of reactive oxygen species (ros) is increased in cultured gingival fibroblasts (gf) from patients with down syndrome (ds). |
2014-04-22 |
2023-08-12 |
Not clear |
| D L Hill, E P Parks, B S Zemel, J Shults, V A Stallings, N Stettle. Resting energy expenditure and adiposity accretion among children with Down syndrome: a 3-year prospective study. European journal of clinical nutrition. vol 67. issue 10. 2014-04-22. PMID:23900244. |
children with down syndrome (ds) have a higher prevalence of obesity than other children. |
2014-04-22 |
2023-08-12 |
Not clear |
| Sanghamitra Bandyopadhyay, Catherine Cahill, Amelie Balleidier, Conan Huang, Debomoy K Lahiri, Xudong Huang, Jack T Roger. Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease. PloS one. vol 8. issue 7. 2014-04-21. PMID:23935819. |
our data evidenced a novel therapeutic strategy of potential impact for people with trisomy of the app gene on chromosome 21, which is a phenotype long associated with down syndrome (ds) that can also cause familial alzheimer's disease. |
2014-04-21 |
2023-08-12 |
mouse |
| Florian Friedmacher, Prem Pur. Hirschsprung's disease associated with Down syndrome: a meta-analysis of incidence, functional outcomes and mortality. Pediatric surgery international. vol 29. issue 9. 2014-04-11. PMID:23943251. |
down syndrome (ds) is the most frequent chromosomal abnormality associated with hirschsprung's disease (hd). |
2014-04-11 |
2023-08-12 |
Not clear |
| Paul Yoder, Tiffany Woynaroski, Marc Fey, Steven Warre. Effects of dose frequency of early communication intervention in young children with and without Down syndrome. American journal on intellectual and developmental disabilities. vol 119. issue 1. 2014-04-01. PMID:24450319. |
non-down syndrome (nds) and down syndrome (ds) subgroups were matched on intelligence, mental age, and chronological age. |
2014-04-01 |
2023-08-12 |
Not clear |
| John Timothy Caldwell, Holly Edwards, Alan A Dombkowski, Steven A Buck, Larry H Matherly, Yubin Ge, Jeffrey W Tau. Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia. PloS one. vol 8. issue 7. 2014-03-31. PMID:23874683. |
furthermore, pediatric down syndrome (ds) patients with acute megakaryocytic leukemia (amkl), whose blast cells almost universally harbor somatic mutations in exon 2 of the transcription factor gene gata1, demonstrate increased overall survival relative to non-ds pediatric patients, suggesting a potential role for gata1 in chemotherapy response. |
2014-03-31 |
2023-08-12 |
Not clear |
| Renata Valdívia Lucisano, Luzia Iara Pfeifer, Maria Paula Panuncio Pinto, Jair Lício Ferreira Santos, Patrícia Páfaro Gomes Anhã. [Social interactions of preschool children with Down syndrome during extracurricular activities]. Revista brasileira de enfermagem. vol 66. issue 1. 2014-03-28. PMID:23681389. |
the aim of this research was to identify the process of social interaction of children with down syndrome (ds) during extracurricular activities in the regular early childhood education in ribeirão preto-sp, brazil. |
2014-03-28 |
2023-08-12 |
Not clear |
| Marit Erna Austeng, Harriet Akre, Britt Øverland, Michael Abdelnoor, Eva-Signe Falkenberg, Kari Jorunn Kværne. Otitis media with effusion in children with in Down syndrome. International journal of pediatric otorhinolaryngology. vol 77. issue 8. 2014-03-26. PMID:23790958. |
to determine the prevalence of otitis media with effusion (ome) in children with down syndrome (ds), and the associated to hearing loss at the age of 8 years. |
2014-03-26 |
2023-08-12 |
Not clear |
| George T Capone, Jenna M Aidikoff, Kay Taylor, Natalie Rykie. Adolescents and young adults with Down syndrome presenting to a medical clinic with depression: co-morbid obstructive sleep apnea. American journal of medical genetics. Part A. vol 161A. issue 9. 2014-03-26. PMID:23913657. |
adolescents and young adults with down syndrome (ds) sometimes experience new-onset mood disorder and decline in adaptive skills. |
2014-03-26 |
2023-08-12 |
human |
| E Terblanche, P-H Boe. The functional fitness capacity of adults with Down syndrome in South Africa. Journal of intellectual disability research : JIDR. vol 57. issue 9. 2014-03-25. PMID:22775247. |
persons with down syndrome (ds) are especially at risk because of physical and health impairments, as well as perceived and real barriers to participation in exercise. |
2014-03-25 |
2023-08-12 |
Not clear |
| J Visootsak, B Hess, R Bakeman, L B Adamso. Effect of congenital heart defects on language development in toddlers with Down syndrome. Journal of intellectual disability research : JIDR. vol 57. issue 9. 2014-03-25. PMID:22998351. |
down syndrome (ds, omim #190685) is the most commonly identified genetic form of intellectual disability with congenital heart defect (chd) occurring in 50% of cases. |
2014-03-25 |
2023-08-12 |
Not clear |
| Ishita Das, Joo-Min Park, Jung H Shin, Soo Kyeong Jeon, Hernan Lorenzi, David J Linden, Paul F Worley, Roger H Reeve. Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. Science translational medicine. vol 5. issue 201. 2014-03-25. PMID:24005160. |
down syndrome (ds) is among the most frequent genetic causes of intellectual disability, and ameliorating this deficit is a major goal in support of people with trisomy 21. |
2014-03-25 |
2023-08-12 |
mouse |
| Ariadna Laguna, María-José Barallobre, Miguel-Ángel Marchena, Catarina Mateus, Erika Ramírez, Carmen Martínez-Cue, Jean M Delabar, Miguel Castelo-Branco, Pedro de la Villa, Maria L Arboné. Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome. Human molecular genetics. vol 22. issue 14. 2014-03-24. PMID:23512985. |
down syndrome (ds) results from the triplication of approximately 300 human chromosome 21 (hsa21) genes and affects almost all body organs. |
2014-03-24 |
2023-08-12 |
mouse |
| Aarti Ruparelia, Matthew L Pearn, William C Moble. Aging and intellectual disability: insights from mouse models of Down syndrome. Developmental disabilities research reviews. vol 18. issue 1. 2014-03-24. PMID:23949828. |
down syndrome (ds) is one of many causes of intellectual disability (id), others including but not limited to, fetal alcohol syndrome, fragile x syndrome, rett syndrome, williams syndrome, hypoxia, and infection. |
2014-03-24 |
2023-08-12 |
mouse |
| Warren B Zigma. Atypical aging in Down syndrome. Developmental disabilities research reviews. vol 18. issue 1. 2014-03-24. PMID:23949829. |
at present, there may be over 210,000 people with down syndrome (ds) over the age of 55 in the united states (us) who have significant needs for augmented services due to circumstances related to ordinary and/or pathological aging. |
2014-03-24 |
2023-08-12 |
human |
| Jillian L Shaw, Karen T Chan. Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling. PLoS genetics. vol 9. issue 9. 2014-03-21. PMID:24086147. |
post-mortem brains from down syndrome (ds) and alzheimer's disease (ad) patients show an upregulation of the down syndrome critical region 1 protein (dscr1), but its contribution to ad is not known. |
2014-03-21 |
2023-08-12 |
drosophila_melanogaster |
| Keiichi Ishihar. [Identification of molecules with altered expression in the brain of mouse model for Down syndrome by comprehensive analyses]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 133. issue 9. 2014-03-20. PMID:23995807. |
down syndrome (ds), caused by triplication of human chromosome 21, is the most common aneuploidy. |
2014-03-20 |
2023-08-12 |
mouse |
| Alberto C S Costa, Jonah J Scott-McKea. Prospects for improving brain function in individuals with Down syndrome. CNS drugs. vol 27. issue 9. 2014-03-19. PMID:23821040. |
down syndrome (ds), which results from an extra copy of chromosome 21 (trisomy 21), is the most common genetically defined cause of intellectual disability. |
2014-03-19 |
2023-08-12 |
mouse |
| Shahida Moosa, David G Segal, Arnold L Christianson, Nerine E Gregerse. Thyroid dysfunction in a cohort of South African children with Down syndrome. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. vol 103. issue 12 Suppl 1. 2014-03-13. PMID:24300639. |
while international studies show thyroid dysfunction occurs more commonly in individuals with down syndrome (ds) than in the general population, there is a paucity of available data from sub-saharan africa. |
2014-03-13 |
2023-08-12 |
Not clear |
| M Reza Sailani, Periklis Makrythanasis, Armand Valsesia, Federico A Santoni, Samuel Deutsch, Konstantin Popadin, Christelle Borel, Eugenia Migliavacca, Andrew J Sharp, Genevieve Duriaux Sail, Emilie Falconnet, Kelly Rabionet, Clara Serra-Juhé, Stefano Vicari, Daniela Laux, Yann Grattau, Guy Dembour, Andre Megarbane, Renaud Touraine, Samantha Stora, Sofia Kitsiou, Helena Fryssira, Chariklia Chatzisevastou-Loukidou, Emmanouel Kanavakis, Giuseppe Merla, Damien Bonnet, Luis A Pérez-Jurado, Xavier Estivill, Jean M Delabar, Stylianos E Antonaraki. The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome. Genome research. vol 23. issue 9. 2014-03-11. PMID:23783273. |
congenital heart defect (chd) occurs in 40% of down syndrome (ds) cases. |
2014-03-11 |
2023-08-12 |
Not clear |