| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Devsmita Das, Cristy Phillips, Wayne Hsieh, Krithika Sumanth, Van Dang, Ahmad Saleh. Neurotransmitter-based strategies for the treatment of cognitive dysfunction in Down syndrome. Progress in neuro-psychopharmacology & biological psychiatry. vol 54. 2015-05-12. PMID:24842803. |
down syndrome (ds) is a multisystem disorder affecting the cardiovascular, respiratory, gastrointestinal, neurological, hematopoietic, and musculoskeletal systems and is characterized by significant cognitive disability and a possible common pathogenic mechanism with alzheimer's disease. |
2015-05-12 |
2023-08-13 |
mouse |
| Kaishi Satomi, Mari Yoshida, Kentaro Matsuoka, Hajime Okita, Yosuke Hosoya, Yoko Shioda, Masa-Aki Kumagai, Tetsuya Mori, Yukio Morishita, Masayuki Noguchi, Atsuko Nakazaw. Myelopathy mimicking subacute combined degeneration in a Down syndrome patient with methotrexate treatment for B lymphoblastic leukemia: report of an autopsy case. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 34. issue 4. 2015-05-11. PMID:24661121. |
we report clinicopathological features of a 23-year-old woman with down syndrome (ds) presenting with subacute myelopathy treated with chemotherapy, including intravenous and intrathecal administration of methotrexate (mtx), and with allogenic bone-marrow transplantation for b lymphoblastic leukemia. |
2015-05-11 |
2023-08-12 |
Not clear |
| Thanarat Layangool, Chaisit Sangtawesin, Tawatchai Kirawittaya, Worakan Prompan, Pimpak Prachasilchai, Amornrat Pechdamrongsaku. Survival analysis of Down syndrome with congenital heart disease: a 5-years registry at QSNICH. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 97 Suppl 6. 2015-05-08. PMID:25391181. |
down syndrome (ds) is the most common chromosomal abnormality in children. |
2015-05-08 |
2023-08-13 |
Not clear |
| Jetanachai Pravi. Bronchoscopic findings in Down syndrome children with respiratory problems. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. vol 97 Suppl 6. 2015-05-08. PMID:25391189. |
down syndrome (ds) can affect the upper and lower respiratory tract in a number of ways and disorders of other systems can impact upon respiratory function, giving rise to a wide variety of respiratory manifestations. |
2015-05-08 |
2023-08-13 |
Not clear |
| Rita Carsetti, Diletta Valentini, Valentina Marcellini, Marco Scarsella, Emiliano Marasco, Ferruccio Giustini, Andrea Bartuli, Alberto Villani, Alberto G Ugazi. Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome. European journal of immunology. vol 45. issue 3. 2015-05-08. PMID:25472482. |
children with down syndrome (ds) have increased susceptibility to infections and a high frequency of leukemia and autoimmune disorders, suggesting that immunodeficiency and immune dysfunction are integral parts of the syndrome. |
2015-05-08 |
2023-08-13 |
Not clear |
| Jianhua Wu, Toyin Ajisaf. Kinetic patterns of treadmill walking in preadolescents with and without Down syndrome. Gait & posture. vol 39. issue 1. 2015-05-07. PMID:23953274. |
this study investigated the effect of both walking speed and external ankle load on the kinetic patterns of treadmill walking in preadolescents with and without down syndrome (ds). |
2015-05-07 |
2023-08-12 |
Not clear |
| Giles My Tan, Felix Beacher, Eileen Daly, Jamie Horder, Verinder Prasher, Maria-Luisa Hanney, Robin Morris, Simon Lovestone, Kieran C Murphy, Andrew Simmons, Declan Gm Murph. Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS). Journal of neurodevelopmental disorders. vol 6. issue 1. 2015-05-04. PMID:25937842. |
down syndrome (ds), or trisomy 21, is one of the most common autosomal mutations. |
2015-05-04 |
2023-08-13 |
Not clear |
| Dulanjalee Kariyawasam, Latif Rachdi, Aurore Carré, Mercè Martin, Marine Houlier, Nathalie Janel, Jean-Maurice Delabar, Raphaël Scharfmann, Michel Pola. DYRK1A BAC transgenic mouse: a new model of thyroid dysgenesis in Down syndrome. Endocrinology. vol 156. issue 3. 2015-04-29. PMID:25490145. |
the most common thyroid abnormality among down syndrome (ds) children corresponds to a mildly elevated tsh, with t4 decreased or in the normal range and thyroid hypoplasia, from the neonatal period onward, which aggravate their mental impairment. |
2015-04-29 |
2023-08-13 |
mouse |
| Lital Shaham, Elena Vendramini, Yubin Ge, Yaron Goren, Yehudit Birger, Marloes R Tijssen, Maureen McNulty, Ifat Geron, Omer Schwartzman, Liat Goldberg, Stella T Chou, Holly Pitman, Mitchell J Weiss, Shulamit Michaeli, Benjamin Sredni, Berthold Göttgens, John D Crispino, Jeffrey W Taub, Shai Izrael. MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome. Blood. vol 125. issue 8. 2015-04-24. PMID:25533034. |
children with down syndrome (ds) are at increased risk for acute myeloid leukemias (ml-ds) characterized by mixed megakaryocytic and erythroid phenotype and by acquired mutations in the gata1 gene resulting in a short gata1s isoform. |
2015-04-24 |
2023-08-13 |
mouse |
| Ana Carolina de Campos, Larissa Carvalho Vanzo Cerra, Fernanda Pereira Dos Santos Silva, Nelci Adriana Cicuto Ferreira Roch. Bimanual coordination in typical and atypical infants: movement initiation, object touching and grasping. Research in developmental disabilities. vol 35. issue 10. 2015-04-23. PMID:24973549. |
we investigated the development of uni- and bimanual actions in typically-developing (td) infants and infants with down syndrome (ds) while they reached for objects with varying sizes. |
2015-04-23 |
2023-08-13 |
human |
| Stamatis Agiovlasitis, Lindy M Rossow, Huimin Yan, Sushant M Ranadive, Christopher A Fahs, Robert W Motl, Bo Fernhal. Predicting METs from the heart rate index in persons with Down syndrome. Research in developmental disabilities. vol 35. issue 10. 2015-04-23. PMID:24981191. |
persons with down syndrome (ds) have altered heart rate modulation and very low aerobic fitness. |
2015-04-23 |
2023-08-13 |
human |
| Jessica A Ash, Ramon Velazquez, Christy M Kelley, Brian E Powers, Stephen D Ginsberg, Elliott J Mufson, Barbara J Strup. Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice. Neurobiology of disease. vol 70. 2015-04-21. PMID:24932939. |
down syndrome (ds) is marked by intellectual disability (id) and early-onset of alzheimer's disease (ad) neuropathology, including basal forebrain cholinergic neuron (bfcn) degeneration. |
2015-04-21 |
2023-08-13 |
mouse |
| Chitra Lal, David R White, Jane E Joseph, Karen van Bakergem, Angela LaRos. Sleep-disordered breathing in Down syndrome. Chest. vol 147. issue 2. 2015-04-21. PMID:25644910. |
osa is much more common and severe in patients with down syndrome (ds) than in the general population, yet there is a striking lack of literature in this area. |
2015-04-21 |
2023-08-13 |
Not clear |
| Neera Ghaziuddin, Armin Nassiri, Judith H Mile. Catatonia in Down syndrome; a treatable cause of regression. Neuropsychiatric disease and treatment. vol 11. 2015-04-21. PMID:25897230. |
the main aim of this case series report is to alert physicians to the occurrence of catatonia in down syndrome (ds). |
2015-04-21 |
2023-08-13 |
Not clear |
| Miguel Galeote, Pilar Soto, Eugenia Sebastián, Elena Checa, Concepción Sánchez-Palacio. Early grammatical development in Spanish children with Down syndrome. Journal of child language. vol 41. issue 1. 2015-04-20. PMID:23286320. |
the objective of this work was to analyze morphosyntactic development in a wide sample of children with down syndrome (ds) (n = 92) and children with typical development (td) (n = 92) with a mental age (ma) of 20 to 29 months. |
2015-04-20 |
2023-08-12 |
Not clear |
| S R Yasin, L H Tahtamouni, N S Najeeb, N M Issa, Z A Al-Mazaydeh, A A Alfaour. Genomic integrity of the Y chromosome sequence-tagged-sites in infertile and Down syndrome Jordanian males. Andrologia. vol 46. issue 7. 2015-04-20. PMID:23957314. |
in this preliminary study, we attempted to screen the presence or absence of twenty y chromosome's sequence-tagged sites (sts) associated with fertility in infertile and down syndrome (ds) males. |
2015-04-20 |
2023-08-12 |
Not clear |
| Elhadi H Aburawi, Nicolas Nagelkerke, Asma Deeb, Shahrban Abdulla, Yousef M Abdulrazza. National growth charts for United Arab Emirates children with Down syndrome from birth to 15 years of age. Journal of epidemiology. vol 25. issue 1. 2015-04-20. PMID:25196167. |
specific centile growth charts for children with down syndrome (ds) have been produced in many countries and are known to differ from those of normal children. |
2015-04-20 |
2023-08-13 |
Not clear |
| Jamie O Edgin, Goffredina Spanò, Kevin Kawa, Lynn Nade. Remembering things without context: development matters. Child development. vol 85. issue 4. 2015-04-17. PMID:24597709. |
to understand the development of these effects, context effects on object recognition were tested in neurotypical children ages 3 years to adulthood (n 3-6 years = 34, n 10-16 years = 32, n college age = 22) and individuals with down syndrome (ds) ages 10-29 years (n = 21). |
2015-04-17 |
2023-08-12 |
human |
| M Galli, V Cimolin, C Rigoldi, M Pau, P Costici, G Albertin. The effects of low arched feet on foot rotation during gait in children with Down syndrome. Journal of intellectual disability research : JIDR. vol 58. issue 8. 2015-04-17. PMID:24750182. |
in children with down syndrome (ds) hypotonia and ligament laxity are characteristic features which cause a number of orthopaedic issues, such as flat foot. |
2015-04-17 |
2023-08-13 |
Not clear |
| Devi Dayal, Puneet Jain, Inusha Panigrahi, Anish Bhattacharya, Naresh Sachdev. Thyroid dysfunction in Indian children with Down syndrome. Indian pediatrics. vol 51. issue 9. 2015-04-17. PMID:25228616. |
this record review of 82 children with down syndrome (ds) between april 2004 and march 2014 who had thyroid dysfunction, showed that majority (76, 92.6%) had subclinical hypothyroidism. |
2015-04-17 |
2023-08-13 |
Not clear |