| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meenal Gupta, A Ranjitha Dhanasekaran, Katheleen J Gardine. Mouse models of Down syndrome: gene content and consequences. Mammalian genome : official journal of the International Mammalian Genome Society. vol 27. issue 11-12. 2018-01-02. PMID:27538963. |
down syndrome (ds), trisomy of human chromosome 21 (hsa21), is challenging to model in mice. |
2018-01-02 |
2023-08-13 |
mouse |
| Joanna Zawitkowska, Teresa Odój, Katarzyna Drabko, Agnieszka Zaucha-Prażmo, Julia Rudnicka, Michał Romiszewski, Michał Matysiak, Kinga Kwiecińska, Magdalena Ćwiklińska, Walentyna Balwierz, Joanna Owoc-Lempach, Katarzyna Derwich, Jacek Wachowiak, Maciej Niedźwiecki, Elżbieta Adamkiewicz-Drożyńska, Joanna Trelińska, Wojciech Młynarski, Andrzej Kołtan, Mariusz Wysocki, Renata Tomaszewska, Tomasz Szczepański, Marcin Płonowski, Maryna Krawczuk-Rybak, Tomasz Ociepa, Tomasz Urasiński, Agnieszka Mizia-Malarz, Grażyna Sobol-Milejska, Grażyna Karolczyk, Jerzy Kowalczy. Outcome of acute lymphoblastic leukemia in children with down syndrome-Polish pediatric leukemia and lymphoma study group report. Pediatric hematology and oncology. vol 34. issue 4. 2018-01-02. PMID:29040012. |
children with down syndrome (ds) have a 20-fold increased risk of developing leukemia compared with the general population. |
2018-01-02 |
2023-08-13 |
Not clear |
| Joanna Zawitkowska, Teresa Odój, Katarzyna Drabko, Agnieszka Zaucha-Prażmo, Julia Rudnicka, Michał Romiszewski, Michał Matysiak, Kinga Kwiecińska, Magdalena Ćwiklińska, Walentyna Balwierz, Joanna Owoc-Lempach, Katarzyna Derwich, Jacek Wachowiak, Maciej Niedźwiecki, Elżbieta Adamkiewicz-Drożyńska, Joanna Trelińska, Wojciech Młynarski, Andrzej Kołtan, Mariusz Wysocki, Renata Tomaszewska, Tomasz Szczepański, Marcin Płonowski, Maryna Krawczuk-Rybak, Tomasz Ociepa, Tomasz Urasiński, Agnieszka Mizia-Malarz, Grażyna Sobol-Milejska, Grażyna Karolczyk, Jerzy Kowalczy. Outcome of acute lymphoblastic leukemia in children with down syndrome-Polish pediatric leukemia and lymphoma study group report. Pediatric hematology and oncology. vol 34. issue 4. 2018-01-02. PMID:29040012. |
the study was based on children with all and down syndrome who were treated with an identical therapy schedule as all patients without ds, according to risk group. |
2018-01-02 |
2023-08-13 |
Not clear |
| Sevket Balli, Ilker Kemal Yucel, Ayse Esin Kibar, Ibrahim Ece, Eylem Sen Dalkiran, Sukru Canda. Assessment of cardiac function in absence of congenital and acquired heart disease in patients with Down syndrome. World journal of pediatrics : WJP. vol 12. issue 4. 2017-12-26. PMID:27059745. |
extra genetic material in patients with down syndrome (ds) may affect the function of any organ system. |
2017-12-26 |
2023-08-13 |
Not clear |
| Jonas F Ludvigsson, Benjamin Lebwohl, Peter H R Green, Wendy K Chung, Karl Måril. Celiac disease and Down syndrome mortality: a nationwide cohort study. BMC pediatrics. vol 17. issue 1. 2017-12-26. PMID:28143429. |
individuals with down syndrome (ds) have increased mortality and are also at increased risk of celiac disease (cd). |
2017-12-26 |
2023-08-13 |
Not clear |
| Yohei Miyake, Jun-Ichi Adachi, Tomonari Suzuki, Kazuhiko Mishima, Atsushi Sasaki, Ryo Nishikaw. Craniospinal Germinomas in Patient with Down Syndrome Successfully Treated with Standard-Dose Chemotherapy and Craniospinal Irradiation: Case Report and Literature Review. World neurosurgery. vol 108. 2017-12-26. PMID:28919233. |
patients with down syndrome (ds) are more likely to develop chemotherapy-related complications. |
2017-12-26 |
2023-08-13 |
Not clear |
| Takashi Kasai, Harutsugu Tatebe, Masaki Kondo, Ryotaro Ishii, Takuma Ohmichi, Wing Tung Esther Yeung, Masafumi Morimoto, Tomohiro Chiyonobu, Naoto Terada, David Allsop, Masanori Nakagawa, Toshiki Mizuno, Takahiko Tokud. Increased levels of plasma total tau in adult Down syndrome. PloS one. vol 12. issue 11. 2017-12-26. PMID:29190730. |
down syndrome (ds) is the most prevalent chromosomal abnormality. |
2017-12-26 |
2023-08-13 |
human |
| Saied Ghadersohi, Jonathan B Ida, Bharat Bhushan, Kathleen R Billing. Outcomes of tympanoplasty in children with down syndrome. International journal of pediatric otorhinolaryngology. vol 103. 2017-12-26. PMID:29224762. |
the prevalence of chronic otitis media with effusion (come), and eustachian tube dysfunction (etd) is high in down syndrome (ds) patients. |
2017-12-26 |
2023-08-13 |
Not clear |
| Jacobo Limeres Posse, Julian López Jiménez, José C Ruiz Villandiego, Antonio Cutando Soriano, Javier Fernández Feijoo, Maialen Linazasoro Elorza, Márcio Diniz Freitas, Pedro Diz Dio. Survival of dental implants in patients with Down syndrome: A case series. The Journal of prosthetic dentistry. vol 116. issue 6. 2017-12-22. PMID:27460329. |
the need for tooth replacement in individuals with down syndrome (ds) is explained by the high prevalence of dental agenesis and by the premature loss of teeth through severe periodontal disease. |
2017-12-22 |
2023-08-13 |
Not clear |
| Dhananjay Radhakrishnan Subramaniam, Goutham Mylavarapu, Robert J Fleck, Raouf S Amin, Sally R Shott, Ephraim J Gutmar. Effect of airflow and material models on tissue displacement for surgical planning of pharyngeal airways in pediatric down syndrome patients. Journal of the mechanical behavior of biomedical materials. vol 71. 2017-12-21. PMID:28292706. |
the objective of this study is to evaluate the effect of airflow parameters and material model on soft tissue displacement for planning surgical treatment in pediatric patients with osa and down syndrome (ds). |
2017-12-21 |
2023-08-13 |
Not clear |
| David S Stein, Kerim M Munir, Andrea J Karweck, Emily J Davidson, Martin T Stei. Developmental Regression, Depression, and Psychosocial Stress in an Adolescent with Down Syndrome. Journal of developmental and behavioral pediatrics : JDBP. vol 38 Suppl 1. 2017-12-20. PMID:28141713. |
kristen is a 13-year-old girl with down syndrome (ds) who was seen urgently with concerns of cognitive and developmental regression including loss of language, social, and toileting skills. |
2017-12-20 |
2023-08-13 |
Not clear |
| Eric D Hamlett, Edward J Goetzl, Aurélie Ledreux, Vitaly Vasilevko, Heather A Boger, Angela LaRosa, David Clark, Steven L Carroll, María Carmona-Iragui, Juan Fortea, Elliott J Mufson, Marwan Sabbagh, Abdul H Mohammed, Dean Hartley, Eric Doran, Ira T Lott, Ann-Charlotte Granhol. Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 13. issue 5. 2017-12-18. PMID:27755974. |
individuals with down syndrome (ds) exhibit alzheimer's disease (ad) neuropathology and dementia early in life. |
2017-12-18 |
2023-08-13 |
Not clear |
| Somchit Jaruratanasirikul, Ounjai Kor-Anantakul, Montira Chowvichian, Wannee Limpitikul, Pathikan Dissaneevate, Nitthakarn Intharasangkanawin, Atchara Sattapanyo, Sermsri Pathompanitrat, H Sriplun. A population-based study of prevalence of Down syndrome in Southern Thailand. World journal of pediatrics : WJP. vol 13. issue 1. 2017-12-15. PMID:27878784. |
down syndrome (ds) is the most common chromosomal disorder that causes mental retardation. |
2017-12-15 |
2023-08-13 |
Not clear |
| Ranjan Bista, David W Lee, Oliver B Pepper, David O Azorsa, Robert J Arceci, Eiman Alee. Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells. Journal of experimental & clinical cancer research : CR. vol 36. issue 1. 2017-12-13. PMID:28143565. |
children with down syndrome (ds) have increased risk for developing aml (ds-amkl), and they usually experience severe therapy-related toxicities compared to non ds-amkl. |
2017-12-13 |
2023-08-13 |
Not clear |
| Zhuo Xing, Yichen Li, Annie Pao, Abigail S Bennett, Benjamin Tycko, William C Mobley, Y Eugene Y. Mouse-based genetic modeling and analysis of Down syndrome. British medical bulletin. vol 120. issue 1. 2017-12-11. PMID:27789459. |
down syndrome (ds), caused by human trisomy 21 (ts21), can be considered as a prototypical model for understanding the effects of chromosomal aneuploidies in other diseases. |
2017-12-11 |
2023-08-13 |
mouse |
| André Vinicius Marcondes Natel Sales, Célia Maria Giacheti, Paula Cristina Cola, Roberta Gonçalves da Silv. Qualitative and quantitative analysis of oropharyngeal swallowing in Down syndrome. CoDAS. vol 29. issue 6. 2017-12-11. PMID:29069232. |
to describe the qualitative and quantitative temporal analysis of oropharyngeal swallowing in children diagnosed with down syndrome (ds) through a case series study of six individuals aged 4 to 17 months (mean age = 11.16 months; median = 12 months). |
2017-12-11 |
2023-08-13 |
Not clear |
| Anna J Esbensen, Dean W Beebe, Kelly C Byars, Emily K Hoffma. Use of Sleep Evaluations and Treatments in Children with Down Syndrome. Journal of developmental and behavioral pediatrics : JDBP. vol 37. issue 8. 2017-12-08. PMID:27541580. |
to characterize practice patterns regarding sleep evaluation and intervention among children with down syndrome (ds). |
2017-12-08 |
2023-08-13 |
Not clear |
| M F Mattos, L Uback, P M Biselli-Chicote, J M Biselli, E M Goloni-Bertollo, E C Pavarin. Polymorphisms of interleukin 6 in Down syndrome individuals: a case-control study. Genetics and molecular research : GMR. vol 16. issue 3. 2017-12-07. PMID:28829905. |
down syndrome (ds) individuals present impaired adaptive immune system. |
2017-12-07 |
2023-08-13 |
Not clear |
| M Florencia Iulita, Alison Ower, Concetta Barone, Rowan Pentz, Palma Gubert, Corrado Romano, Rita Anna Cantarella, Flaviana Elia, Serafino Buono, Marilena Recupero, Carmelo Romano, Sabrina Castellano, Paolo Bosco, Santo Di Nuovo, Filippo Drago, Filippo Caraci, A Claudio Cuell. An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 12. issue 11. 2017-12-01. PMID:27452424. |
given that alzheimer's pathology develops silently over decades in down syndrome (ds), prognostic biomarkers of dementia are a major need. |
2017-12-01 |
2023-08-13 |
Not clear |
| Jenifer Lavigne, Christianne Sharr, Ibrahim Elsharkawi, Al Ozonoff, Nicole Baumer, Campbell Brasington, Sheila Cannon, Blythe Crissman, Emily Davidson, Jose C Florez, Priya Kishnani, Angela Lombardo, Jordan Lyerly, Mary Ellen McDonough, Alison Schwartz, Kathryn Berrier, Susan Sparks, Kara Stock-Guild, Tomi L Toler, Kishore Vellody, Lauren Voelz, Brian G Skotk. Thyroid dysfunction in patients with Down syndrome: Results from a multi-institutional registry study. American journal of medical genetics. Part A. vol 173. issue 6. 2017-12-01. PMID:28332275. |
the goals of this undertaking were to assess the outcomes of thyroid screening tests and adherence to thyroid screening guidelines across five down syndrome (ds) specialty clinics in various states. |
2017-12-01 |
2023-08-13 |
human |