| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth Chorvinsky, Surajit Bhattacharya, Betelehem Solomon Bera, Allison Welham, Karim Ismat, Claire M Lawlor, Diego Preciado, Jose L Gomez, Hiroki Morizono, Dinesh K Pillai, Maria J Gutierrez, Jyoti K Jaiswal, Gustavo Nin. Dysregulated airway epithelial antiviral immunity in Down Syndrome impairs type III IFN response and amplifies airway inflammation during RSV infection. bioRxiv : the preprint server for biology. 2024-12-09. PMID:39651190. |
trisomy 21 (ts21), also known as down syndrome (ds), increases pediatric mortality risk from respiratory syncytial virus (rsv) by nine-fold, yet its underlying immunological basis remains unclear. |
2024-12-09 |
2024-12-12 |
Not clear |
| Mitsuhiro Masaki, Yuka Iizuka, Karin Sugawara, Yuki Uchikawa, Honoka Isobe, Fuyumi Hattori, Koki Mano, Keiko Saito, Ayaka Sugino, Kana Kato, Kenji Sakain. Association of walking and activities of daily living with muscle thickness of the trunk and lower extremity muscles in children with down syndrome. Developmental neurorehabilitation. 2024-12-09. PMID:39651966. |
we examined the association of walking and activities of daily living(adl) with trunk and lower extremity muscle thickness in children with down syndrome (ds). |
2024-12-09 |
2024-12-12 |
Not clear |
| Weili Shi, Shixiu Lia. [Research progress on the cognitive deficit of Down syndrome patients]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 41. issue 12. 2024-12-09. PMID:39653359. |
as the most common chromosomal disorder compatible to life, down syndrome (ds) is caused by an extra copy of chromosome 21. |
2024-12-09 |
2024-12-12 |
Not clear |
| Atsushi Kohso, Hidemi Toyoda, Ryo Hanaki, Kaori Niwa, Yosuke Okumura, Mari Morimoto, Takahiro Ito, Masahiro Hirayam. Inotuzumab ozogamicin for relapse prevention in a boy with Down syndrome and relapsed acute lymphoblastic leukemia. International journal of hematology. 2024-12-08. PMID:39648271. |
children with down syndrome (ds) have an increased risk of bcp-all and higher rates of relapse and toxicity, including treatment-related mortality. |
2024-12-08 |
2024-12-11 |
Not clear |
| Jingjing Zhang, Yuuya Kohzuka, Kathleen M Bennett, Fernanda R Almeid. Case reports of oral appliance therapy on three young adults with Down syndrome and OSA. Journal of prosthodontics : official journal of the American College of Prosthodontists. 2024-12-04. PMID:39632349. |
patients with down syndrome (ds) have a high incidence of obstructive sleep apnea (osa) due to hypotonia, weight, underdeveloped midface, and relative macroglossia. |
2024-12-04 |
2024-12-07 |
Not clear |
| Sara R Sherman, Ronald Jackson, Natalia S Lima, Brooks A Hibner, Bo Fernhall, Tracy Baynar. Blunted Exercise Pressor Response to Isometric Knee Extension and Post Exercise Ischemia in Individuals with Down Syndrome. Medicine and science in sports and exercise. 2024-12-03. PMID:39625363. |
individuals with down syndrome (ds) exhibit autonomic dysfunction, which contributes to reduced work capacity. |
2024-12-03 |
2024-12-06 |
Not clear |
| Sanae Yamazaki, Jun Miyauchi, Hideaki Sato, Yuko Takahashi, Takayuki Amikur. Autopsy case of a stillbirth with transient abnormal myelopoiesis associated with Down syndrome: Immunohistochemical demonstration of GATA1 mutation in placental tissues. Pathology international. 2024-12-02. PMID:39620384. |
transient abnormal myelopoiesis (tam) in neonates with down syndrome (ds) exhibits hematological features that are indistinguishable from those of acute megakaryoblastic leukemia. |
2024-12-02 |
2024-12-06 |
Not clear |
| Ahmed Nageeb Mahmoud, John Paul Prodoehl, Maria F Echeverry-Martinez, Daniel S Horwit. Hemiarthroplasty for Hip Fracture in Down Syndrome: A Retrospective Series of Five Cases. Hip & pelvis. vol 36. issue 4. 2024-12-02. PMID:39620569. |
there is limited evidence regarding the outcomes of hip hemiarthroplasty (ha) following trauma in individuals living with down syndrome (ds). |
2024-12-02 |
2024-12-06 |
Not clear |
| Michael J Foster, Jeffrey Chu, Jacqueline Shaia, Rishi P Singh, Katherine E Talcot. Prevalence and diversity of retinal disease in adults with Down syndrome. Eye (London, England). 2024-11-29. PMID:39613904. |
while epidemiologic data exists for some ophthalmic diseases in people with down syndrome (ds), like strabismus and amblyopia, no studies explore the prevalence of retinal disease in people with ds on a large scale. |
2024-11-29 |
2024-12-02 |
Not clear |
| Michael J Foster, Jeffrey Chu, Jacqueline Shaia, Rishi P Singh, Katherine E Talcot. Prevalence and diversity of retinal disease in adults with Down syndrome. Eye (London, England). 2024-11-29. PMID:39613904. |
to evaluate previous studies on physiology and/or anatomy in retinal models representing ds or in the retinas of people with ds, all relevant terms related to down syndrome, retina, and retinal diseases were searched in pubmed and scopus. |
2024-11-29 |
2024-12-02 |
Not clear |
| Melissa J Alldred, Kyrillos W Ibrahim, Harshitha Pidikiti, Gabriela Chiosis, Elliott J Mufson, Grace E Stutzmann, Stephen D Ginsber. Down syndrome frontal cortex layer III and layer V pyramidal neurons exhibit lamina specific degeneration in aged individuals. Acta neuropathologica communications. vol 12. issue 1. 2024-11-28. PMID:39605035. |
selective vulnerability of neuronal populations occurs in both down syndrome (ds) and alzheimer's disease (ad), resulting in disproportional degeneration of pyramidal neurons (pns) affecting memory and executive function. |
2024-11-28 |
2024-11-30 |
human |
| Stephanie L Santoro, Ayesha Harisinghani, Caroline Bregman, Clorinda Cottrell, Margaret B Pulsifer, Mikayla Shaffer, Amy Torres, Brian G Skotko, Nicolas M Oreskovi. Implementing a Quality Improvement Initiative to Screen for Dementia in a Down Syndrome Specialty Clinic. American journal of medical genetics. Part A. 2024-11-28. PMID:39607288. |
using quality improvement methods, we aimed to implement a protocol to assess for dementia among adults with down syndrome (ds). |
2024-11-28 |
2024-11-30 |
Not clear |
| Letícia Abdelnour Zuanon, Juliana Dela Líbera, João Victor Soares Rodrigues, Pedro Henrique Petrilli, Alexia Ribeiro Horikawa, Márcio José Possari Dos Santos, Letícia Helena Theodoro, Karina Helga Leal Turci. Pressure pain threshold of the mastigatory muscles and reaction to touch in adults with down syndrome and neurotypicals: cross-sectional study. Journal of bodywork and movement therapies. vol 40. 2024-11-27. PMID:39593493. |
down syndrome (ds) is currently the most common chromosomal condition associated with intellectual disability in the global population and is characterized by a variety of additional clinical findings. |
2024-11-27 |
2024-11-29 |
Not clear |
| Marina Piñar-Lara, Irene Cortés-Pérez, Ángeles Díaz-Fernández, María de Alharilla Montilla-Ibáñez, Ana Sedeño-Vidal, Esteban Obrero-Gaitá. Virtual Reality-Based Therapy Can Enhance Balance and Muscular Endurance in Children and Adolescents with Down Syndrome: A Systematic Review with a Meta-Analysis. Bioengineering (Basel, Switzerland). vol 11. issue 11. 2024-11-27. PMID:39593772. |
physical exercises are crucial for enhancing postural balance and muscle strength in children and adolescents with down syndrome (ds). |
2024-11-27 |
2024-11-29 |
human |
| Karthik Mouli, Anton V Liopo, Larry J Suva, Kenneth R Olson, Emily A McHugh, James M Tour, Paul J Derry, Thomas A Ken. SOD1 Is an Integral Yet Insufficient Oxidizer of Hydrogen Sulfide in Trisomy 21 B Lymphocytes and Can Be Augmented by a Pleiotropic Carbon Nanozyme. Antioxidants (Basel, Switzerland). vol 13. issue 11. 2024-11-27. PMID:39594503. |
down syndrome (ds) is a multisystemic disorder that includes accelerated aging caused by trisomy 21. |
2024-11-27 |
2024-11-29 |
Not clear |
| Julya Ribeiro Campos, Fernando Oliveira Costa, Ana Cristina Borges-Oliveira, Luís Otávio Miranda Cot. Stress and Self-Efficacy in Parents/Caregivers and Oral Health of Individuals with Down Syndrome During the COVID-19 Pandemic: A Cross-Sectional Study. International journal of environmental research and public health. vol 21. issue 11. 2024-11-27. PMID:39595764. |
the family of individuals living with down syndrome (ds) often demonstrate high levels of stress associated with the demand for care and difficulties experienced in everyday life. |
2024-11-27 |
2024-11-29 |
Not clear |
| Alberto C S Cost. On the Therapeutic Use of Monoclonal Antibodies Against Amyloid Plaques in Older Adults with Down Syndrome: A Narrative Review and Perspective. Brain sciences. vol 14. issue 11. 2024-11-27. PMID:39595846. |
down syndrome (ds) is a genetic disorder caused by an extra copy of chromosome 21 (trisomy 21 or t21) and is associated with an increased risk of early-onset alzheimer's disease (ad), also known as ds-associated ad (dsad). |
2024-11-27 |
2024-11-29 |
Not clear |
| Ana Gutierrez-Hervas, Esther Nova, Rocío Izquierdo-Gómez, Óscar L Veiga, Carmen Padilla, José Castro-Piñero, Ascensión Marcos, Sonia Gómez-Martíne. Association Between Lifestyle Patterns and Abdominal Obesity with Biochemical and Inflammatory Biomarkers in Adolescents with Down Syndrome: The UP&DOWN Study. Nutrients. vol 16. issue 22. 2024-11-27. PMID:39599670. |
the main objective of this study was to examine the association between lifestyle patterns (physical activity, screen and sleep time and diet) and abdominal obesity, and endocrine, metabolic, and immunological biomarkers in adolescents with down syndrome (ds). |
2024-11-27 |
2024-11-29 |
Not clear |
| Darren R Hocking, Elysse Byer, Nancy Raitano Le. Delineation of cross-domain associations between everyday executive function and adaptive behaviour in Down syndrome and Williams syndrome. Scientific reports. vol 14. issue 1. 2024-11-26. PMID:39587171. |
in genetic syndromes such as down syndrome (ds) and williams syndrome (ws), difficulties with executive functioning (ef) are a commonly reported feature and a key correlate of long-term success in everyday life. |
2024-11-26 |
2024-11-28 |
Not clear |
| Herminia Diana Rosas, Nathaniel David Mercaldo, Yasemin Hasimoglu, Melissa Petersen, Lydia R Lewis, Florence Lai, David Powell, Asim Dhungana, Ali Demir, David Keater, Michael Yassa, Adam M Brickman, Sid O'Bryan. Association of plasma neurofilament light chain with microstructural white matter changes in Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 16. issue 4. 2024-11-25. PMID:39583646. |
both micro- and macrostructural white matter (wm) abnormalities, particularly those related to axonal degeneration, are associated with cognitive decline in adults with down syndrome (ds) prior to a diagnosis of alzheimer disease. |
2024-11-25 |
2024-11-27 |
Not clear |