| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diana Lupu, Anca Pop, Julien Cherfan, Béla Kiss, Felicia Loghi. In vitro modulation of estrogen receptor activity by norfluoxetine. Clujul medical (1957). vol 88. issue 3. 2015-11-26. PMID:26609274. |
selective serotonin reuptake inhibitors (ssris) are antidepressants increasingly prescribed for pregnancy and postpartum depression. |
2015-11-26 |
2023-08-13 |
Not clear |
| Daniela Zahn, Frank Petrak, Leonora Franke, Anna-Karolina Hägele, Georg Juckel, Florian Lederbogen, Horst Neubauer, Christine Norra, Idun Uhl, Stephan Herpert. Cortisol, platelet serotonin content, and platelet activity in patients with major depression and type 2 diabetes: an exploratory investigation. Psychosomatic medicine. vol 77. issue 2. 2015-11-20. PMID:25626989. |
cortisol, platelet serotonin content, and platelet activity in patients with major depression and type 2 diabetes: an exploratory investigation. |
2015-11-20 |
2023-08-13 |
Not clear |
| Daniela Zahn, Frank Petrak, Leonora Franke, Anna-Karolina Hägele, Georg Juckel, Florian Lederbogen, Horst Neubauer, Christine Norra, Idun Uhl, Stephan Herpert. Cortisol, platelet serotonin content, and platelet activity in patients with major depression and type 2 diabetes: an exploratory investigation. Psychosomatic medicine. vol 77. issue 2. 2015-11-20. PMID:25626989. |
this exploratory study examined associations between cortisol parameters, platelet serotonin (5-ht) content, and platelet activity markers in patients with newly diagnosed major depression (md) and/or type 2 diabetes (t2dm) compared with healthy controls. |
2015-11-20 |
2023-08-13 |
Not clear |
| Desmond J Oathes, Lori M Hilt, Jack B Nitschk. Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. PloS one. vol 10. issue 2. 2015-11-20. PMID:25675343. |
affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. |
2015-11-20 |
2023-08-13 |
human |
| Desmond J Oathes, Lori M Hilt, Jack B Nitschk. Affective neural responses modulated by serotonin transporter genotype in clinical anxiety and depression. PloS one. vol 10. issue 2. 2015-11-20. PMID:25675343. |
these findings link the serotonin transporter gene to affective circuitry findings in anxiety and depression psychopathology and further suggest that its impact on patients may be different from effects typically observed in healthy populations. |
2015-11-20 |
2023-08-13 |
human |
| Ofelia Limón-Morales, Cesar Soria-Fregozo, Marcela Arteaga-Silva, Marisela Hernández González, Gonzalo Vázquez-Palacios, Herlinda Bonilla-Jaim. Hormone replacement with 17β-estradiol plus dihydrotestosterone restores male sexual behavior in rats treated neonatally with clomipramine. Hormones and behavior. vol 66. issue 5. 2015-11-17. PMID:25449595. |
in experiments, neonatal treatment with clomipramine (cmi; a serotonin reuptake inhibitor) reproduces some of the signs of depression in adult age, including reduced sexual behavior manifested in a lower percentage of subjects that mount, intromit and ejaculate, although their testosterone levels were not altered. |
2015-11-17 |
2023-08-13 |
human |
| Cornelia Walther, Fabiana A Caetano, Henry A Dunn, Stephen S G Ferguso. PDZK1/NHERF3 differentially regulates corticotropin-releasing factor receptor 1 and serotonin 2A receptor signaling and endocytosis. Cellular signalling. vol 27. issue 3. 2015-11-17. PMID:25562428. |
the corticotropin-releasing factor receptor 1 (crfr1) and serotonin 2a receptor (5-ht2ar) are linked to cellular mechanisms underlying stress anxiety and depression. |
2015-11-17 |
2023-08-13 |
Not clear |
| Benjamin D Sachs, Ramona M Rodriguiz, Ha L Tran, Akshita Iyer, William C Wetsel, Marc G Caro. Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience. Psychoneuroendocrinology. vol 53. 2015-11-17. PMID:25602134. |
these findings may have important implications for our understanding of the combinatorial roles of 5-ht deficiency, els, and postpartum depression in the development of neuropsychiatric disorders. |
2015-11-17 |
2023-08-13 |
mouse |
| Yi Liu, Hui Feng, Hongjing Mao, Yali Mo, Yan Yin, Wenjuan Liu, Mingfen Song, Shengdong Wan. [Impact on serum 5-HT and TH1/TH2 in patients of depressive disorder at acute stage treated with acupuncture and western medication]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 35. issue 6. 2015-11-12. PMID:26480546. |
to compare the difference in depression relief in the treatment of depressive disorder at the acute stage between the combined therapy of acupuncture and 5-ht (5-hydroxytryptamine) selective serotonini reuptake inhibitors (ssris) and the single application of ssris and explore the impact on the imbalance of 5-ht and th1/th2. |
2015-11-12 |
2023-08-13 |
Not clear |
| Jihyung Hong, Diego Novick, William Montgomery, Maria Victoria Moneta, Héctor Dueñas, Xiaomei Peng, Josep Maria Har. Health-related quality of life in patients with depression treated with duloxetine or a selective serotonin reuptake inhibitor in a naturalistic outpatient setting. Patient preference and adherence. vol 9. 2015-11-03. PMID:26527865. |
health-related quality of life in patients with depression treated with duloxetine or a selective serotonin reuptake inhibitor in a naturalistic outpatient setting. |
2015-11-03 |
2023-08-13 |
Not clear |
| Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Nieves Herrera-Mundo, Catherine E Sykes, Dina M Francescutti, Donald M Kuh. Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype. ACS chemical neuroscience. vol 5. issue 10. 2015-11-02. PMID:25089765. |
reductions in function within the serotonin (5ht) neuronal system have long been proposed as etiological factors in depression. |
2015-11-02 |
2023-08-13 |
mouse |
| Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Nieves Herrera-Mundo, Catherine E Sykes, Dina M Francescutti, Donald M Kuh. Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype. ACS chemical neuroscience. vol 5. issue 10. 2015-11-02. PMID:25089765. |
the time differential between the onset of 5ht reuptake inhibition by ssris (minutes) and onset of their antidepressant efficacy (weeks to months), when considered with their overall poor therapeutic effectiveness, has cast some doubt on the role of 5ht in depression. |
2015-11-02 |
2023-08-13 |
mouse |
| Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Nieves Herrera-Mundo, Catherine E Sykes, Dina M Francescutti, Donald M Kuh. Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype. ACS chemical neuroscience. vol 5. issue 10. 2015-11-02. PMID:25089765. |
the behavioral phenotype of the tph2(-/-) mouse questions the role of 5ht in depression. |
2015-11-02 |
2023-08-13 |
mouse |
| Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Nieves Herrera-Mundo, Catherine E Sykes, Dina M Francescutti, Donald M Kuh. Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype. ACS chemical neuroscience. vol 5. issue 10. 2015-11-02. PMID:25089765. |
furthermore, the tph2(-/-) mouse may serve as a useful model in the search for new medications that have therapeutic targets for depression that are outside of the 5ht neuronal system. |
2015-11-02 |
2023-08-13 |
mouse |
| K Little, C A Olsson, S Whittle, G J Youssef, M L Byrne, J G Simmons, M Yücel, D L Foley, N B Alle. Association between serotonin transporter genotype, brain structure and adolescent-onset major depressive disorder: a longitudinal prospective study. Translational psychiatry. vol 4. 2015-11-02. PMID:25226554. |
the extent to which brain structural abnormalities might serve as neurobiological endophenotypes that mediate the link between the variation in the promoter of the serotonin transporter gene (5-httlpr) and depression is currently unknown. |
2015-11-02 |
2023-08-13 |
Not clear |
| Cathy Southammakosane, Kristine Schmit. Pediatric Psychopharmacology for Treatment of ADHD, Depression, and Anxiety. Pediatrics. vol 136. issue 2. 2015-10-28. PMID:26148950. |
the use of selective serotonin reuptake inhibitors is considered first-line psychopharmacology for depression and anxiety symptoms. |
2015-10-28 |
2023-08-13 |
Not clear |
| Na Li, Qun Liu, Xiao-Juan Li, Xiao-Hui Bai, Yue-Yun Liu, Hong-Bo Zhao, Zhong-Ye Jin, Yu-Xia Jing, Zhi-Yi Yan, Jia-Xu Che. TCM Formula Xiaoyaosan Decoction Improves Depressive-Like Behaviors in Rats with Type 2 Diabetes. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-10-28. PMID:26508978. |
the body weight, fasting blood glucose, itt, ogtt, 5-ht, da, depression behaviors, and morphological changes of formation were measured and observed. |
2015-10-28 |
2023-08-13 |
rat |
| Carl Björkholm, Olivia Frånberg, Anna Malmerfelt, Monica M Marcus, Åsa Konradsson-Geuken, Björn Schilström, Kent Jardemark, Torgny H Svensso. Adjunctive treatment with asenapine augments the escitalopram-induced effects on monoaminergic outflow and glutamatergic neurotransmission in the medial prefrontal cortex of the rat. The international journal of neuropsychopharmacology. vol 18. issue 3. 2015-10-27. PMID:25522408. |
substantial clinical data support the addition of low doses of atypical antipsychotic drugs to selective serotonin reuptake inhibitors (ssris) to rapidly enhance the antidepressant effect in treatment-resistant depression. |
2015-10-27 |
2023-08-13 |
rat |
| Jana Haase, Eric Brow. Integrating the monoamine, neurotrophin and cytokine hypotheses of depression--a central role for the serotonin transporter? Pharmacology & therapeutics. vol 147. 2015-10-26. PMID:25444754. |
integrating the monoamine, neurotrophin and cytokine hypotheses of depression--a central role for the serotonin transporter? |
2015-10-26 |
2023-08-13 |
Not clear |
| Jana Haase, Eric Brow. Integrating the monoamine, neurotrophin and cytokine hypotheses of depression--a central role for the serotonin transporter? Pharmacology & therapeutics. vol 147. 2015-10-26. PMID:25444754. |
this review will focus firstly on the interconnected roles of serotonin and neurotrophins in depression and antidepressant therapy, secondly on the impact of the immune system on serotonin transporter regulation and neurotrophin signalling and finally we propose a model of reciprocal regulation of serotonin and neurotrophin signalling in the context of inflammation-induced depression. |
2015-10-26 |
2023-08-13 |
Not clear |