Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Peisen Zhong, Xinyu Mao, Na Li, Li Chen, Jianbo Su. Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT. Journal of medicinal chemistry. 2024-08-27. PMID:39189331. |
the occurrence of depression is closely related to the decrease in serotonin (5-ht) levels in the synaptic cleft. |
2024-08-27 |
2024-08-30 |
Not clear |
Ariel R Goldenthal, Evan Lieberman, Mina M Rizk, R Todd Ogden, Harry Rubin-Falcone, Francesca Zanderigo, Yung-Yu Huang, Eli Min, Minlan Yuan, Matthew Milak, Gregory M Sullivan, M Elizabeth Sublette, Maria A Oquendo, J John Mann, Jeffrey M Mille. Relationships between serotonin 1A receptor DNA methylation, self-reported history of childhood abuse and gray matter volume in major depression. Journal of affective disorders. 2024-08-26. PMID:39187183. |
relationships between serotonin 1a receptor dna methylation, self-reported history of childhood abuse and gray matter volume in major depression. |
2024-08-26 |
2024-08-30 |
Not clear |
Yukiko Hori, Haruhiko Iwaoki, Koki Mimura, Yuji Nagai, Makoto Higuchi, Takafumi Minamimot. Effects of a 5-HT Scientific reports. vol 14. issue 1. 2024-08-23. PMID:39179718. |
effects of a 5-ht temporal discounting, in which the recipient of a reward perceives the value of that reward to decrease with delay in its receipt, is associated with impulsivity and psychiatric disorders such as depression. |
2024-08-23 |
2024-08-27 |
Not clear |
Kira J Kazi, Cole D English, Emma Ivantsova, Christopher L Souders Ii, Christopher J Martyniu. Transcriptome networks and physiology related to cardiac function and motor activity are perturbed in larval zebrafish (Danio rerio) following exposure to the antidepressant citalopram. Environmental pollution (Barking, Essex : 1987). 2024-08-21. PMID:39168440. |
citalopram is a selective serotonin reuptake inhibitor used to treat depression and is often detected in aquatic environments. |
2024-08-21 |
2024-08-24 |
zebrafish |
Michael V Heinz, Elad Yom-Tov, Daniel M Mackin, Rina Matsumura, Nicholas C Jacobso. A large-scale observational comparison of antidepressants and their effects. Journal of psychiatric research. vol 178. 2024-08-20. PMID:39163659. |
selective serotonin reuptake inhibitors (ssris) represent a diverse class of medications widely prescribed for depression and anxiety. |
2024-08-20 |
2024-08-23 |
Not clear |
Qinyu Jiang, Yu Qi, Meiyan Zhou, Yaqi Dong, Wenting Zheng, Lijiao Zhu, Yanyu Li, Hai Zhou, Liwei Wan. Effect of esketamine on serum neurotransmitters in patients with postpartum depression: a randomized controlled trial. BMC anesthesiology. vol 24. issue 1. 2024-08-19. PMID:39160473. |
the development of postpartum depression has been linked to fluctuations in the levels of neurotransmitters in the human body, such as 5-hydroxytryptamine (5-ht), dopamine (da), noradrenaline (norepinephrine, ne), and brain derived neurotrophic factor (bdnf). |
2024-08-19 |
2024-08-22 |
human |
Yan-Bin Wei, Yong-Bo Wang, Jia-Yue Sun, Shan Wang, Jun Nan, Hai-Ling Yu, Yan La. N-palmitoylethanolamide attenuates negative emotions induced by morphine withdrawal in mice. Neuroscience letters. 2024-08-18. PMID:39154843. |
the findings indicate that pea mitigated anxiety and depression symptoms and reduced 5-hydroxytryptamine, noradrenaline, and dopamine levels in the hippocampus and prefrontal cortex. |
2024-08-18 |
2024-08-21 |
mouse |
Cailing Chen, Zhiyao Zheng, Kan Gao, Qiuling Fan, Yanjun Li, Su Che. Prophylactic effects of supplementation of a combination of Lactobacillus lactis WHH2078 and saffron on depressive-like behaviors in mice exposed to chronic stress. Journal of food science. 2024-08-10. PMID:39126686. |
the serotonin (5-hydroxytryptamine [5-ht]) metabolism through the gut-brain axis has been revealed to be related to the development of depression. |
2024-08-10 |
2024-08-13 |
mouse |
Cailing Chen, Zhiyao Zheng, Kan Gao, Qiuling Fan, Yanjun Li, Su Che. Prophylactic effects of supplementation of a combination of Lactobacillus lactis WHH2078 and saffron on depressive-like behaviors in mice exposed to chronic stress. Journal of food science. 2024-08-10. PMID:39126686. |
our previous study demonstrated that lactococcus lactis whh2078 alleviated depression in mice by shaping the gut microbiome composition and 5-ht metabolism. |
2024-08-10 |
2024-08-13 |
mouse |
Amy L Salisbury, George M Anderson, Amy Yang, Catherine S Stika, Laura J Rasmussen-Torvik, Jacqueline K Gollan, Katherine L Wisne. Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-08-10. PMID:39127823. |
in non-exposed mothers and infants, platelet 5-ht levels were not affected by the presence of maternal depression. |
2024-08-10 |
2024-08-13 |
human |
Yanping Wang, Min Guo, Yuanyuan Li, Yan Chen, Hong Wei, Xiaohui Mo, Guolin Chai, Yongling Du, Fangdi H. Development of a dual-template molecularly imprinted electrochemical sensor for the simultaneous detection of depression markers 5-HT and Glu. Mikrochimica acta. vol 191. issue 9. 2024-08-09. PMID:39120734. |
development of a dual-template molecularly imprinted electrochemical sensor for the simultaneous detection of depression markers 5-ht and glu. |
2024-08-09 |
2024-08-12 |
mouse |
Yanping Wang, Min Guo, Yuanyuan Li, Yan Chen, Hong Wei, Xiaohui Mo, Guolin Chai, Yongling Du, Fangdi H. Development of a dual-template molecularly imprinted electrochemical sensor for the simultaneous detection of depression markers 5-HT and Glu. Mikrochimica acta. vol 191. issue 9. 2024-08-09. PMID:39120734. |
it was successfully utilized to simultaneously detect glu and 5-ht in mouse serum, offering a more dependable foundation for objectively diagnosing and early warning of depression. |
2024-08-09 |
2024-08-12 |
mouse |
Shi Bai, Zhong-Ming Ying, Jia-Kang Ying, Qin-Ying Zhang, Yu-Hang Lv, Zhong-Min W. Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats. Journal of neurophysiology. 2024-08-07. PMID:39110517. |
5-hydroxytryptamine (5-ht) plays a substantial role in mitigating depression and anxiety. |
2024-08-07 |
2024-08-10 |
rat |
Grace C Lin, Julia Tevini, Lisa Mair, Heinz-Peter Friedl, Dietmar Fuchs, Thomas Felder, Johanna M Gostner, Winfried Neuhau. Investigations Towards Tryptophan Uptake and Transport Across an In Vitro Model of the Oral Mucosa Epithelium. International journal of tryptophan research : IJTR. vol 17. 2024-08-02. PMID:39092002. |
as a progenitor of serotonin, altered tryptophan levels have been related to several neurogenerative diseases as well as depression or anxiety. |
2024-08-02 |
2024-08-05 |
human |
Jesse Markman, Heidi Comb. Newer Treatments for Mood and Anxiety Disorders. The Medical clinics of North America. vol 108. issue 5. 2024-07-31. PMID:39084841. |
for more than 20 years, the mainstay of pharmacologic treatment for depression and anxiety disorders has been serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitors. |
2024-07-31 |
2024-08-03 |
Not clear |
Annabel Maurer, Adrian Lieb, Stephan Bongar. Internalizing psychological symptoms in children and adolescents with fructose malabsorption. Frontiers in psychology. vol 15. 2024-07-29. PMID:39070588. |
a deficiency of serotonin may cause internalizing mental disorders like depression and anxiety, and a fructose-oriented eating behavior may affect these symptoms. |
2024-07-29 |
2024-08-02 |
Not clear |
Ankit N Patel, Jagdish Varma, Barna Gangul. Evidence of the Immunomodulatory Effects of Selective Serotonin Reuptake Inhibitors in Patients With Depression Through a Systematic Review. Cureus. vol 16. issue 6. 2024-07-26. PMID:39050288. |
evidence of the immunomodulatory effects of selective serotonin reuptake inhibitors in patients with depression through a systematic review. |
2024-07-26 |
2024-07-28 |
Not clear |
Jiahao Li, Rujia Zhong, Yi Guo, Feng Zhan. Eye disorders associated with selective serotonin reuptake inhibitors: a real-world disproportionality analysis of FDA adverse event reporting system. Expert opinion on drug safety. 2024-07-25. PMID:39051730. |
selective serotonin reuptake inhibitors (ssris) are widely used in depression and other psychiatric disorders. |
2024-07-25 |
2024-07-28 |
Not clear |
Mengjie Su, Wenjing Peng, Zhengyuan Ding, Yaqiu Zhou, Hui Gao, Qiyu Jiang, Chunmei Y. Multi-walled carbon nanotubes-metal-organic framework nanocomposite based sensor for the monitoring of multiple monoamine neurotransmitters in living cells. Bioelectrochemistry (Amsterdam, Netherlands). vol 160. 2024-07-17. PMID:39018612. |
the levels of monoamine neurotransmitters (mnts) including dopamine (da), adrenaline (adr), norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in cells are useful indicators to explore the pathogenesis of mnts-related diseases such as alzheimer's disease, parkinson's disease and depression. |
2024-07-17 |
2024-07-20 |
Not clear |
Lizhou Yue, Huawei Huang, Weiying Li. Development of a Highly Specific Fluorescent Probe based on Thiol-ene Click Nucleophilic Cascade Reactions for Delving into the Action Mechanism of Serotonin in Depression. Angewandte Chemie (International ed. in English). 2024-07-12. PMID:38995157. |
development of a highly specific fluorescent probe based on thiol-ene click nucleophilic cascade reactions for delving into the action mechanism of serotonin in depression. |
2024-07-12 |
2024-07-14 |
Not clear |