| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wael Y Khawagi, Hayder M Al-Kuraishy, Nawar R Hussein, Ali I Al-Gareeb, Esraa Atef, Omnya Elhussieny, Athanasios Alexiou, Marios Papadakis, Majid S Jabir, Abdullah A Alshehri, Hebatallah M Saad, Gaber El-Saber Batih. Depression and type 2 diabetes: A causal relationship and mechanistic pathway. Diabetes, obesity & metabolism. vol 26. issue 8. 2024-07-09. PMID:38802993. |
hyperglycaemia and dyslipidaemia promote the incidence of depression by enhancing inflammation and reducing brain serotonin (5-hydroxytryptamine [5ht]). |
2024-07-09 |
2024-07-12 |
Not clear |
| Wael Y Khawagi, Hayder M Al-Kuraishy, Nawar R Hussein, Ali I Al-Gareeb, Esraa Atef, Omnya Elhussieny, Athanasios Alexiou, Marios Papadakis, Majid S Jabir, Abdullah A Alshehri, Hebatallah M Saad, Gaber El-Saber Batih. Depression and type 2 diabetes: A causal relationship and mechanistic pathway. Diabetes, obesity & metabolism. vol 26. issue 8. 2024-07-09. PMID:38802993. |
dysregulation of insulin signalling in t2d impairs brain 5ht signalling, leading to the development of depression. |
2024-07-09 |
2024-07-12 |
Not clear |
| Yu-Long Zhao, Hui-Yuan Yi, Sani Sa'idu Baba, Yi-Xiao Guo, Xiao-Cui Yuan, Xue-Mei Hou, Ling-Li Liang, Fu-Quan Hu. Activation of 5-HT Molecular neurobiology. 2024-07-04. PMID:38963532. |
activation of 5-ht the comorbidity of anxiety and depression frequently occurs in patients with neuropathic pain. |
2024-07-04 |
2024-07-10 |
Not clear |
| Yundeng Xiaowen, Jingxuan Zhu, Mingming Gong, Ge Meng, Renran Tan, Yanbing Zhang, Zhiyu Che. Effect of depression and the antidepressant fluoxetine on osseointegration-A pre-clinical in vivo experimental study. Clinical oral implants research. 2024-07-04. PMID:38963167. |
the aim of this study was to explore the effect of depression and selective serotonin reuptake inhibitors on implant osseointegration and bone healing. |
2024-07-04 |
2024-07-10 |
Not clear |
| Renjie Gao, Panpan Zhao, Kai Ya. Selective Serotonin Reuptake Inhibitors for the Treatment of Depression in Parkinson's Disease: A Systematic Review and Meta-Analysis. Clinical drug investigation. 2024-07-03. PMID:38960993. |
selective serotonin reuptake inhibitors for the treatment of depression in parkinson's disease: a systematic review and meta-analysis. |
2024-07-03 |
2024-07-10 |
Not clear |
| Vincenzo Cardaci, Matteo Carminati, Mattia Tondello, Basilio Pecorino, Alessandro Serretti, Raffaella Zanard. Understanding and treating postpartum depression: a narrative review. International clinical psychopharmacology. 2024-06-28. PMID:38941162. |
treatment may differ from the traditional major depression management, while selective serotonin reuptake inhibitors such as sertraline are commonly used and suggested by guidelines, neurosteroids such as brexanolone and the more convenient zuranolone have been recently approved. |
2024-06-28 |
2024-07-01 |
Not clear |
| Cem Yamali, Merve Nenni, Mehtap Tugrak Sakarya, Hasan Alper Kapla. Pharmaceutical Studies on Piperazine-Based Compounds Targeting Serotonin Receptors and Serotonin Reuptake Transporters. Mini reviews in medicinal chemistry. 2024-06-24. PMID:38910275. |
gene polymorphisms related to 5-hydroxytryptamine (5-ht) signaling and subtypes of 5-ht receptors may play a role in the development of depression and the response to antidepressants. |
2024-06-24 |
2024-06-26 |
Not clear |
| Cem Yamali, Merve Nenni, Mehtap Tugrak Sakarya, Hasan Alper Kapla. Pharmaceutical Studies on Piperazine-Based Compounds Targeting Serotonin Receptors and Serotonin Reuptake Transporters. Mini reviews in medicinal chemistry. 2024-06-24. PMID:38910275. |
ssris binding to 5-ht reuptake transporters help relieve depression symptoms. |
2024-06-24 |
2024-06-26 |
Not clear |
| Arman Shafiee, Kyana Jafarabady, Niloofar Seighali, Ida Mohammadi, Shahryar Rajai Firouz Abadi, Faeze Soltani Abhari, Mahmood Bakhtiyar. Effect of Saffron Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment of Depression and Anxiety: A Meta-analysis of Randomized Controlled Trials. Nutrition reviews. 2024-06-24. PMID:38913392. |
effect of saffron versus selective serotonin reuptake inhibitors (ssris) in treatment of depression and anxiety: a meta-analysis of randomized controlled trials. |
2024-06-24 |
2024-06-26 |
Not clear |
| Maurizio Bossola, Ilaria Mariani, Manuela Antocicco, Gilda Pepe, Anna Petrosino, Enrico Di Stasi. Selective Serotonin Reuptake Inhibitors and Symptoms of Depression in Patients on Chronic Hemodialysis: A Systematic Review. Journal of clinical medicine. vol 13. issue 11. 2024-06-19. PMID:38893046. |
selective serotonin reuptake inhibitors and symptoms of depression in patients on chronic hemodialysis: a systematic review. |
2024-06-19 |
2024-06-21 |
Not clear |
| Hanan S Althagafy, Emad H M Hassanei. Fluoxetine attenuates chlorpyrifos-induced neuronal injury through the PPARγ, SIRT1, NF-κB, and JAK1/STAT3 signals. International immunopharmacology. vol 136. 2024-06-15. PMID:38815349. |
fluoxetine (flx) is a selective serotonin reuptake inhibitor (ssri) that is widely prescribed for depression and anxiety disorders. |
2024-06-15 |
2024-06-18 |
rat |
| Lidan Yi, Jing Chen, Sini Li, Wei Cui, Jianhe Li, Liubao Peng, Ciyan Pen. Efficacy and safety of Chinese patent medicines combined with antidepressants for treatment of depression in adults: A multiple-treatment meta-analysis. Journal of psychiatric research. vol 176. 2024-06-15. PMID:38878648. |
combinations of chinese patent medicines (cpm) with antidepressants (including selective serotonin reuptake inhibitors (ssri), selective serotonin-norepinephrine reuptake inhibitors (snri), tricyclic antidepressants (tca), and noradrenergic and specific serotonergic antidepressants (nassa)) are frequently utilized for treating depression in adults. |
2024-06-15 |
2024-06-18 |
Not clear |
| Yingru Zhang, Yan Wan. The dual roles of serotonin in antitumor immunity. Pharmacological research. 2024-06-11. PMID:38862071. |
depression is frequently associated with decreased levels of serotonin with the alternate name 5-hydroxytryptamine (5-ht), leading to the common use of selective serotonin reuptake inhibitors (ssris) as antidepressants. |
2024-06-11 |
2024-06-14 |
human |
| Simran Arora, Ayman Faaez, Pavan Kumar Pyda, Satish Suhas, Vanteemar S Sreeraj, Urvakhsh Meherwan Mehta, John P Joh. A case report of continuous theta-burst transcranial magnetic stimulation induced seizures in a patient with bipolar depression on selective serotonin reuptake inhibitors. Brain stimulation. 2024-06-09. PMID:38852774. |
a case report of continuous theta-burst transcranial magnetic stimulation induced seizures in a patient with bipolar depression on selective serotonin reuptake inhibitors. |
2024-06-09 |
2024-06-14 |
Not clear |
| Sergio Mena, Allison Cruikshank, Janet Best, H F Nijhout, Michael C Reed, Parastoo Hashem. Modulation of serotonin transporter expression by escitalopram under inflammation. Communications biology. vol 7. issue 1. 2024-06-08. PMID:38851804. |
selective serotonin reuptake inhibitors (ssris) are widely used for depression based on the monoamine deficiency hypothesis. |
2024-06-08 |
2024-06-11 |
mouse |
| Rucha Deore, Rashid Ansari, Sanjay N Awathale, Madhav Shelke, Hemant R Badwaik, Sameer N Goyal, Kartik T Nakhat. Lycopene alleviates BCG-induced depressive phenotypes in mice by disrupting 5-HT3 receptor - IDO1 interplay in the brain. European journal of pharmacology. 2024-06-03. PMID:38830456. |
the 5-ht3 receptor and indoleamine 2,3-dioxygenase 1 (ido1) enzyme play a crucial role in the pathogenesis of depression as their activation reduce serotonin contents in the brain. |
2024-06-03 |
2024-06-06 |
mouse |
| Nour Fakih, Marc Fakhour. Alzheimer Disease-Link With Major Depressive Disorder and Efficacy of Antidepressants in Modifying its Trajectory. Journal of psychiatric practice. vol 30. issue 3. 2024-05-31. PMID:38819242. |
antidepressants such as selective serotonin reuptake inhibitors, which are the first line of treatment for mdd, have shown great promise in the treatment of depression in ad, although their effectiveness remains controversial. |
2024-05-31 |
2024-06-06 |
Not clear |
| N Simple Santi, Sashi B Biswal, Birendra Narayan Naik, Jyoti Prakash Sahoo, Bhabagrahi Rat. A Randomized Controlled Trial Comparing Efficacy and Safety of Antidepressant Monotherapy. Cureus. vol 16. issue 4. 2024-05-27. PMID:38800340. |
these issues prompted investigations concerning the various roles of serotonin (5-ht) neurotransmissions in the etiology of depression. |
2024-05-27 |
2024-05-31 |
human |
| Rachel N Schade, Connor B Etheridge, Lauren E Kenney, Adrianna M Ratajska, Katie Rodriguez, Francesca V Lopez, Joshua Gertler, Alyssa Ray, Lauren Santos, Christopher Hess, Dawn Bower. Greater Apathy Associated With Selective Serotonin Reuptake Inhibitor Use in Parkinson's Disease. Journal of geriatric psychiatry and neurology. 2024-05-23. PMID:38780969. |
use of selective serotonin reuptake inhibitors (ssris) has been associated with increased apathy in adolescents and adults with depression. |
2024-05-23 |
2024-05-27 |
Not clear |
| Bingcong Zhao, Zhigang Li, Chuan Shi, Yan Liu, Yang Sun, Bin Li, Jie Zhang, Zhizhong Gong, Yuanzheng Wang, Xuehong Ma, Xinjing Yang, Huili Jiang, Yuanbo Fu, Xin Wang, Yang Li, Hengchia Liu, Tuya Bao, Yutong Fe. Acupuncture as Add-on Therapy to SSRIs Can Improve Outcomes of Treatment for Anxious Depression: Subgroup Analysis of the AcuSDep Trial. Neuropsychiatric disease and treatment. vol 20. 2024-05-21. PMID:38770535. |
this exploratory subgroup analysis aimed to explore the effects of acupuncture as an add-on therapy of selective serotonin reuptake inhibitors (ssris) for patients with ad or non-anxious depression (nad). |
2024-05-21 |
2024-05-27 |
Not clear |