| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Motoko Honda, Mitsuo Tanabe, Hideki On. Spinal cord injury-specific depression of monosynaptic spinal reflex transmission by l-5-hydroxytryptophan results from loss of the 5-HT uptake system and not 5-HT receptor supersensitivity. Experimental neurology. vol 202. issue 1. 2006-12-20. PMID:16806182. |
spinal cord injury-specific depression of monosynaptic spinal reflex transmission by l-5-hydroxytryptophan results from loss of the 5-ht uptake system and not 5-ht receptor supersensitivity. |
2006-12-20 |
2023-08-12 |
rat |
| Motoko Honda, Mitsuo Tanabe, Hideki On. Spinal cord injury-specific depression of monosynaptic spinal reflex transmission by l-5-hydroxytryptophan results from loss of the 5-HT uptake system and not 5-HT receptor supersensitivity. Experimental neurology. vol 202. issue 1. 2006-12-20. PMID:16806182. |
we investigated whether the sci-specific depression of msr by l-5-htp was attributable to postsynaptic supersensitivity of 5-ht receptors or presynaptic loss of the 5-ht uptake system. |
2006-12-20 |
2023-08-12 |
rat |
| Barbara K Martin, Constantine E Frangakis, Paul B Rosenberg, Jacobo E Mintzer, Ira R Katz, Anton P Porsteinsson, Lon S Schneider, Peter V Rabins, Cynthia A Munro, Curtis L Meinert, George Niederehe, Constantine G Lyketso. Design of Depression in Alzheimer's Disease Study-2. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 14. issue 11. 2006-12-15. PMID:17068314. |
to address these issues, the authors present the design of the depression in alzheimer's disease study-2 (diads-2), a randomized, placebo-controlled multicenter trial to evaluate the efficacy and safety of the selective serotonin reuptake inhibitor sertraline for the treatment of depression in people with alzheimer disease. |
2006-12-15 |
2023-08-12 |
Not clear |
| Julia M Santos, Raquel C R Martinez, Marcus L Brandã. Effects of acute and subchronic treatments with fluoxetine and desipramine on the memory of fear in moderate and high-intensity contextual conditioning. European journal of pharmacology. vol 542. issue 1-3. 2006-12-14. PMID:16831418. |
selective serotonin and noradrenalin reuptake inhibitors such as fluoxetine and desipramine, respectively, are efficacious in the treatment of depression and chronic stress. |
2006-12-14 |
2023-08-12 |
rat |
| Matthew J Taylor, Nick Freemantle, John R Geddes, Zubin Bhagwaga. Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis. Archives of general psychiatry. vol 63. issue 11. 2006-12-12. PMID:17088502. |
selective serotonin reuptake inhibitors (ssris) are often described as having a delayed onset of effect in the treatment of depression. |
2006-12-12 |
2023-08-12 |
Not clear |
| Turhan Canli, Maolin Qiu, Kazufumi Omura, Eliza Congdon, Brian W Haas, Zenab Amin, Martin J Herrmann, R Todd Constable, Klaus Peter Lesc. Neural correlates of epigenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 43. 2006-12-06. PMID:17032778. |
the effect of life stress on depression is moderated by a repeat length variation in the transcriptional control region of the serotonin transporter gene, which renders carriers of the short variant vulnerable for depression. |
2006-12-06 |
2023-08-12 |
Not clear |
| Turhan Canli, Maolin Qiu, Kazufumi Omura, Eliza Congdon, Brian W Haas, Zenab Amin, Martin J Herrmann, R Todd Constable, Klaus Peter Lesc. Neural correlates of epigenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 43. 2006-12-06. PMID:17032778. |
based on functional mri and perfusion data, we found support for a model by which life stress interacts with the effect of serotonin transporter genotype on amygdala and hippocampal resting activation, two regions involved in depression and stress. |
2006-12-06 |
2023-08-12 |
Not clear |
| H G M Westenberg, C Sandne. Tolerability and safety of fluvoxamine and other antidepressants. International journal of clinical practice. vol 60. issue 4. 2006-12-04. PMID:16620364. |
selective serotonin [5-hydroxytryptamine (5-ht)] reuptake inhibitors (ssris) and the 5-ht noradrenaline reuptake inhibitor, venlafaxine, are mainstays in treatment for depression. |
2006-12-04 |
2023-08-12 |
Not clear |
| Ejner K Moltzen, Benny Bang-Anderse. Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. Current topics in medicinal chemistry. vol 6. issue 17. 2006-11-30. PMID:17017959. |
serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. |
2006-11-30 |
2023-08-12 |
Not clear |
| Ejner K Moltzen, Benny Bang-Anderse. Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. Current topics in medicinal chemistry. vol 6. issue 17. 2006-11-30. PMID:17017959. |
inhibition of serotonin (5-ht) reuptake has been a central theme in the therapy of depression for half a century. |
2006-11-30 |
2023-08-12 |
Not clear |
| Rosa Maria Moresco, Mario Matarrese, Ferruccio Fazi. PET and SPET molecular imaging: focus on serotonin system. Current topics in medicinal chemistry. vol 6. issue 18. 2006-11-30. PMID:17017972. |
the aim of this paper is to review the principal strategies and the main results of the use of pet or single photon emission tomography (spet) molecular imaging for the in vivo study of serotonin receptors and the main results obtained from their application in the study of major depression. |
2006-11-30 |
2023-08-12 |
human |
| Kristine E Ensrud, Terri L Blackwell, Sonia Ancoli-Israel, Susan Redline, Kristine Yaffe, Susan Diem, David Claman, Katie L Ston. Use of selective serotonin reuptake inhibitors and sleep disturbances in community-dwelling older women. Journal of the American Geriatrics Society. vol 54. issue 10. 2006-11-30. PMID:17038067. |
to determine the association between use of selective serotonin reuptake inhibitors (ssris) and objective measures of sleep disturbances in older community-dwelling women, including women without evidence of depression. |
2006-11-30 |
2023-08-12 |
Not clear |
| Ioannis Paraskevaidis, John T Parissis, Katerina Fountoulaki, Gerasimos Filippatos, Dimitrios Kremastino. Selective serotonin re-uptake inhibitors for the treatment of depression in coronary artery disease and chronic heart failure: evidence for pleiotropic effects. Cardiovascular & hematological agents in medicinal chemistry. vol 4. issue 4. 2006-11-28. PMID:17073612. |
selective serotonin re-uptake inhibitors for the treatment of depression in coronary artery disease and chronic heart failure: evidence for pleiotropic effects. |
2006-11-28 |
2023-08-12 |
Not clear |
| Ioannis Paraskevaidis, John T Parissis, Katerina Fountoulaki, Gerasimos Filippatos, Dimitrios Kremastino. Selective serotonin re-uptake inhibitors for the treatment of depression in coronary artery disease and chronic heart failure: evidence for pleiotropic effects. Cardiovascular & hematological agents in medicinal chemistry. vol 4. issue 4. 2006-11-28. PMID:17073612. |
novel treatment modalities such as selective serotonin re-uptake inhibitors (ssris) may improve depressive symptoms and prognosis of post-myocardial infarction and heart failure patients interacting with the common pathophysiologic mechanisms of depression and cardiovascular disease. |
2006-11-28 |
2023-08-12 |
Not clear |
| J Adan-Manes, J Novalbos, R López-Rodríguez, J L Ayuso-Mateos, F Abad-Santo. Lithium and venlafaxine interaction: a case of serotonin syndrome. Journal of clinical pharmacy and therapeutics. vol 31. issue 4. 2006-11-21. PMID:16882112. |
a 71-year-old woman developed serotonin syndrome while receiving treatment with moderate doses of lithium and venlafaxine for refractory depression. |
2006-11-21 |
2023-08-12 |
Not clear |
| Wayne K Goodman, Eric A Storch, Gary R Geffken, Tanya K Murph. Obsessive-compulsive disorder in Tourette syndrome. Journal of child neurology. vol 21. issue 8. 2006-11-21. PMID:16970872. |
warnings about an increased risk of suicidality among children and adolescents taking antidepressants for pediatric depression extend to those taking the medications for obsessive-compulsive disorder, but the risk-to-benefit ratio is more favorable in this latter population because several serotonin reuptake inhibitors have been shown to be efficacious in obsessive-compulsive disorder. |
2006-11-21 |
2023-08-12 |
Not clear |
| Shuji Iritani, Mizuho Tohgi, Tetsuaki Arai, Kenji Iked. Immunohistochemical study of the serotonergic neuronal system in an animal model of the mood disorder. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16677634. |
to elucidate these issues, we immunohistochemically examined vesicle monoamine transporter 2 (vmat2), serotonin receptor type 1a (5ht1a), and serotonin transporter (5htt) in the hippocampal region of reserpine-treated rats, an animal model of depression. |
2006-11-14 |
2023-08-12 |
rat |
| Catherine Heurteaux, Guillaume Lucas, Nicolas Guy, Malika El Yacoubi, Susanne Thümmler, Xiao-Dong Peng, Florence Noble, Nicolas Blondeau, Catherine Widmann, Marc Borsotto, Gabriella Gobbi, Jean-Marie Vaugeois, Guy Debonnel, Michel Lazdunsk. Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nature neuroscience. vol 9. issue 9. 2006-11-14. PMID:16906152. |
the neurotransmitter serotonin or 5-hydroxytryptamine (5-ht) is involved in the pathophysiology of depression and in the effects of antidepressant treatments. |
2006-11-14 |
2023-08-12 |
mouse |
| Catherine Heurteaux, Guillaume Lucas, Nicolas Guy, Malika El Yacoubi, Susanne Thümmler, Xiao-Dong Peng, Florence Noble, Nicolas Blondeau, Catherine Widmann, Marc Borsotto, Gabriella Gobbi, Jean-Marie Vaugeois, Guy Debonnel, Michel Lazdunsk. Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nature neuroscience. vol 9. issue 9. 2006-11-14. PMID:16906152. |
in mice, the deletion of its gene (kcnk2, also called trek-1) led to animals with an increased efficacy of 5-ht neurotransmission and a resistance to depression in five different models and a substantially reduced elevation of corticosterone levels under stress. |
2006-11-14 |
2023-08-12 |
mouse |
| Zoltán Biró, Russell H Hill, Sten Grillne. 5-HT Modulation of identified segmental premotor interneurons in the lamprey spinal cord. Journal of neurophysiology. vol 96. issue 2. 2006-11-08. PMID:16707720. |
5-ht induced a reduction in the slow afterhyperpolarization and a depression of synaptic transmission in all three types of segmental interneurons. |
2006-11-08 |
2023-08-12 |
Not clear |