| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leo She. Serotonin and suicidal behavior in patients with comorbid depression and alcoholism. The American journal on addictions. vol 15. issue 2. 2007-04-03. PMID:16595360. |
serotonin and suicidal behavior in patients with comorbid depression and alcoholism. |
2007-04-03 |
2023-08-12 |
Not clear |
| Ian B Hickie, Sharon L Naismith, Philip B Ward, Elizabeth M Scott, Philip B Mitchell, Peter R Schofield, Anna Scimone, Kay Wilhelm, Gordon Parke. Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression. Journal of affective disorders. vol 98. issue 1-2. 2007-04-03. PMID:16930719. |
serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression. |
2007-04-03 |
2023-08-12 |
Not clear |
| Ian B Hickie, Sharon L Naismith, Philip B Ward, Elizabeth M Scott, Philip B Mitchell, Peter R Schofield, Anna Scimone, Kay Wilhelm, Gordon Parke. Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression. Journal of affective disorders. vol 98. issue 1-2. 2007-04-03. PMID:16930719. |
although the short allele of the serotonin transporter promoter polymorphism (5-htt) has been linked to increased risk of major depression in early adult life, its relationships with late-life depression and to changes in subcortical nuclei remain unclear. |
2007-04-03 |
2023-08-12 |
Not clear |
| Ho-Joo Lee, Jagadeesh S Rao, Renee N Ertley, Lisa Chang, Stanley I Rapoport, Richard P Bazine. Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat. Psychopharmacology. vol 190. issue 1. 2007-04-03. PMID:17093977. |
fluoxetine is used to treat unipolar depression and is thought to act by increasing the concentration of serotonin (5-ht) in the synaptic cleft, leading to increased serotonin signaling. |
2007-04-03 |
2023-08-12 |
rat |
| D Micheli, C Bonvicini, A Rocchi, R Ceravolo, M Mancuso, G Tognoni, M Gennarelli, G Siciliano, L Murr. No evidence for allelic association of serotonin 2A receptor and transporter gene polymorphisms with depression in Alzheimer disease. Journal of Alzheimer's disease : JAD. vol 10. issue 4. 2007-04-03. PMID:17183148. |
no evidence for allelic association of serotonin 2a receptor and transporter gene polymorphisms with depression in alzheimer disease. |
2007-04-03 |
2023-08-12 |
human |
| Guy Debonnel, Elise Saint-André, Chantal Hébert, Claude de Montigny, Normand Lavoie, Pierre Blie. Differential physiological effects of a low dose and high doses of venlafaxine in major depression. The international journal of neuropsychopharmacology. vol 10. issue 1. 2007-03-30. PMID:16690006. |
the present data showed that, at its minimal effective dose in depression (75 mg/d), venlafaxine acted as a selective 5-ht reuptake inhibitor, whereas when administered at higher doses (225 and 375 mg/d), it acted as a dual 5-ht and ne reuptake inhibitor. |
2007-03-30 |
2023-08-12 |
human |
| Anita H Clayto. Extended-release bupropion: an antidepressant with a broad spectrum of therapeutic activity? Expert opinion on pharmacotherapy. vol 8. issue 4. 2007-03-23. PMID:17309340. |
recent studies have demonstrated additional benefits in depression, including: prevention of the recurrence of seasonal affective disorder in depressive subtypes with decreased energy, pleasure and interest; in major depression with concomitant anxiety; in elderly depressed patients; for non-response to initial serotonin re-uptake inhibitor therapy or augmentation of partial efficacy with serotonin re-uptake inhibitors; and in bipolar depression. |
2007-03-23 |
2023-08-12 |
Not clear |
| Vânia K M Moojen, Márcio Rodrigo Martins, Adalisa Reinke, Gustavo Feier, Fabiano R Agostinho, Edson M Cechin, João Queved. Effects of milnacipran in animal models of anxiety and memory. Neurochemical research. vol 31. issue 4. 2007-03-22. PMID:16758367. |
serotonin (5-ht) and noradrenaline (na) are involved in both pathogenesis and recovery from depression and anxiety. |
2007-03-22 |
2023-08-12 |
rat |
| Sinead M O'Brien, Paul Scully, Peter Fitzgerald, Lucinda V Scott, Timothy G Dina. Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy. Journal of psychiatric research. vol 41. issue 3-4. 2007-03-21. PMID:16870211. |
approximately 30% of patients with depression fail to respond to a selective serotonin reuptake inhibitor (ssri). |
2007-03-21 |
2023-08-12 |
Not clear |
| Mark Hyman Rapapor. Translating the evidence on atypical depression into clinical practice. The Journal of clinical psychiatry. vol 68 Suppl 3. 2007-03-19. PMID:17348765. |
although the introduction of selective serotonin reuptake inhibitors ushered in an era of relative comfort among clinicians in treating major depressive disorder (mdd), no one antidepressant is appropriate for all patients with depression. |
2007-03-19 |
2023-08-12 |
Not clear |
| Richard J Porter, Peter Gallagher, John T O'Brie. Effects of rapid tryptophan depletion on salivary cortisol in older people recovered from depression, and the healthy elderly. Journal of psychopharmacology (Oxford, England). vol 21. issue 1. 2007-03-16. PMID:16533861. |
reduced serotonin (5-ht) function and abnormalities in the hypothalamic-pituitary-adrenal (hpa) axis are thought to play a role in the aetiology of major depression. |
2007-03-16 |
2023-08-12 |
human |
| Richard J Porter, Peter Gallagher, John T O'Brie. Effects of rapid tryptophan depletion on salivary cortisol in older people recovered from depression, and the healthy elderly. Journal of psychopharmacology (Oxford, England). vol 21. issue 1. 2007-03-16. PMID:16533861. |
we sought to examine this issue in the elderly by assessing the effects of lowering brain 5-ht on salivary and plasma cortisol in elderly patients who had recovered from at least one episode of major depression and in a healthy, age matched comparison group. |
2007-03-16 |
2023-08-12 |
human |
| Richard J Porter, Peter Gallagher, John T O'Brie. Effects of rapid tryptophan depletion on salivary cortisol in older people recovered from depression, and the healthy elderly. Journal of psychopharmacology (Oxford, England). vol 21. issue 1. 2007-03-16. PMID:16533861. |
in elderly patients who had recovered from depression there was no evidence of greater vulnerability of hypothalamic 5-ht pathways to 5-ht depletion. |
2007-03-16 |
2023-08-12 |
human |
| Susan C Sharp, Jessica A Helling. Efficacy and safety of selective serotonin reuptake inhibitors in the treatment of depression in children and adolescents: practitioner review. Clinical drug investigation. vol 26. issue 5. 2007-03-16. PMID:17163258. |
efficacy and safety of selective serotonin reuptake inhibitors in the treatment of depression in children and adolescents: practitioner review. |
2007-03-16 |
2023-08-12 |
Not clear |
| Esteve Brugue, Eduard Viet. Atypical antipsychotics in bipolar depression: neurobiological basis and clinical implications. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16876306. |
there is substantial evidence indicating that not only serotonin, but also dopamine may still play an important role as a mediator of antidepressant response in bipolar depression. |
2007-03-15 |
2023-08-12 |
Not clear |
| Esteve Brugue, Eduard Viet. Atypical antipsychotics in bipolar depression: neurobiological basis and clinical implications. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16876306. |
a regionally selective balance between the dopamine and serotonin systems may account for the mood-stabilizing properties of these drugs, and in fact, a low d(2) occupancy might be more relevant to bipolar depression than greater 5-ht(2) action. |
2007-03-15 |
2023-08-12 |
Not clear |
| Takeshi Terao, Takatoshi Hikich. Serotonin syndrome in a case of depression with various somatic symptoms: the difficulty in differential diagnosis. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16916568. |
serotonin syndrome in a case of depression with various somatic symptoms: the difficulty in differential diagnosis. |
2007-03-15 |
2023-08-12 |
Not clear |
| Brandon E Gibb, John E McGeary, Christopher G Beevers, Ivan W Mille. Serotonin transporter (5-HTTLPR) genotype, childhood abuse, and suicide attempts in adult psychiatric inpatients. Suicide & life-threatening behavior. vol 36. issue 6. 2007-03-14. PMID:17250473. |
there is growing evidence that a functional polymorphism in the serotonin transporter gene (5-httlpr) moderates the impact of negative life events (e.g., childhood abuse) on the development of depression. |
2007-03-14 |
2023-08-12 |
Not clear |
| Ender Taner, Esra Yancar Demir, Behcet Cosa. Comparison of the effectiveness of reboxetine versus fluoxetine in patients with atypical depression: a single-blind, randomized clinical trial. Advances in therapy. vol 23. issue 6. 2007-03-14. PMID:17276965. |
this is the first study to compare the efficacy of fluoxetine, a selective reuptake inhibitor of serotonin, and reboxetine, a selective reuptake inhibitor of norepinephrine, in the treatment of patients with atypical depression. |
2007-03-14 |
2023-08-12 |
Not clear |
| Ender Taner, Esra Yancar Demir, Behcet Cosa. Comparison of the effectiveness of reboxetine versus fluoxetine in patients with atypical depression: a single-blind, randomized clinical trial. Advances in therapy. vol 23. issue 6. 2007-03-14. PMID:17276965. |
these findings might suggest that drugs with norepinephrine or a 5-hydroxytryptamine mechanism of action might act through a common pathway, resulting in a similar response in terms of core symptoms of depression. |
2007-03-14 |
2023-08-12 |
Not clear |