| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gyorgy Bagdy, Gabriella Juhasz, Xenia Gond. A new clinical evidence-based gene-environment interaction model of depression. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 14. issue 4. 2013-04-12. PMID:23269207. |
in the newmood cohort polymorphisms of the genes of the serotonin transporter, 5-ht1a, 5-ht1b and 5-ht2a and endocannabinoid cb1 receptors, tryptophan hydroxylase, creb1, bdnf and girk provide evidence for the involvement of these genes in the development of depression. |
2013-04-12 |
2023-08-12 |
human |
| Alexander Sturzu, Sumbla Sheikh, Uwe Klose, Hartmut Echner, Hubert Kalbacher, Martin Deeg, Thomas Nägele, Marius Horger, Ulrike Ernemann, Stefan Heck. Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells. Investigational new drugs. vol 30. issue 6. 2013-04-04. PMID:22212740. |
serotonin plays a role in gastrointestinal functions like intestinal secretion or peristalsis and neuropsychiatric events like depression or migraine. |
2013-04-04 |
2023-08-12 |
human |
| Shao Wan. [Habenula--a new target for treatment of intractable depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 42. issue 6. 2013-04-04. PMID:22363977. |
then, the 5-ht concentration released by the raphe nuclei is increased, the pathological changes of depression is eliminated. |
2013-04-04 |
2023-08-12 |
Not clear |
| Eiko Nakamaru-Ogiso, Hiroyuki Miyamoto, Kozo Hamada, Koji Tsukada, Katsuji Taka. Novel biochemical manipulation of brain serotonin reveals a role of serotonin in the circadian rhythm of sleep-wake cycles. The European journal of neuroscience. vol 35. issue 11. 2013-04-04. PMID:22625848. |
impaired or altered 5-ht neurotransmission appears to be involved in depression and anxiety symptoms, as well as in sleep disorders. |
2013-04-04 |
2023-08-12 |
rat |
| R Avula, A Rand, J L Black, D J O'Kan. Simultaneous genotyping of multiple polymorphisms in human serotonin transporter gene and detection of novel allelic variants. Translational psychiatry. vol 1. 2013-04-04. PMID:22832606. |
selective serotonin reuptake inhibitors block the action of the serotonin transporter and are used to treat depression and other neuropsychiatric disorders. |
2013-04-04 |
2023-08-12 |
human |
| Keren Oved, Ayelet Morag, Metsada Pasmanik-Chor, Varda Oron-Karni, Noam Shomron, Moshe Rehavi, Julia C Stingl, David Gurwit. Genome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkers. Pharmacogenomics. vol 13. issue 10. 2013-04-03. PMID:22909203. |
over 30% of patients with major depression do not respond well to first-line treatment with selective serotonin reuptake inhibitors (ssris). |
2013-04-03 |
2023-08-12 |
human |
| Donatella Marazziti, Stefano Baroni, Michela Picchetti, Armando Piccinni, Stefano Silvestri, Liliana Dell'Oss. [New developments on the serotonin hypothesis of depression: shunt of tryptophan]. Rivista di psichiatria. vol 48. issue 1. 2013-04-01. PMID:23438698. |
[new developments on the serotonin hypothesis of depression: shunt of tryptophan]. |
2013-04-01 |
2023-08-12 |
Not clear |
| Donatella Marazziti, Stefano Baroni, Michela Picchetti, Armando Piccinni, Stefano Silvestri, Liliana Dell'Oss. [New developments on the serotonin hypothesis of depression: shunt of tryptophan]. Rivista di psichiatria. vol 48. issue 1. 2013-04-01. PMID:23438698. |
the finding that the kynurenine causes different effects in central nervous system suggested that an up-regulation of the tryptophan-kynurenine pathway determined not only a deficiency of serotonin, but could also play a role in the development of anxiety, psychotic symptoms and cognitive impairment associated with depression. |
2013-04-01 |
2023-08-12 |
Not clear |
| R X Tan, J C Meng, K Hostettman. Phytochemical investigation of some traditional chinese medicines and endophyte cultures. Pharmaceutical biology. vol 38 Suppl 1. 2013-03-28. PMID:23531135. |
inhibitors of mao a are clinically useful to treat anxiety and depression since they are expected to increase both noradrenalin and serotonin levels in the brain. |
2013-03-28 |
2023-08-12 |
Not clear |
| Irena Nulman, Gideon Koren, Joanne Rovet, Maru Barrera, Ariel Pulver, David Streiner, Brian Feldma. Neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depression. The American journal of psychiatry. vol 169. issue 11. 2013-03-27. PMID:23128923. |
neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depression. |
2013-03-27 |
2023-08-12 |
Not clear |
| Irena Nulman, Gideon Koren, Joanne Rovet, Maru Barrera, Ariel Pulver, David Streiner, Brian Feldma. Neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depression. The American journal of psychiatry. vol 169. issue 11. 2013-03-27. PMID:23128923. |
the authors compared the effects of prenatal exposure to venlafaxine (serotonin-norepinephrine reuptake inhibitor), selective serotonin reuptake inhibitors (ssris), and maternal depression. |
2013-03-27 |
2023-08-12 |
Not clear |
| Jamal A Hanash, Baiba H Hansen, Jørgen F Hansen, Olav W Nielsen, Alice Rasmussen, Morten Birket-Smit. Cardiovascular safety of one-year escitalopram therapy in clinically nondepressed patients with acute coronary syndrome: results from the DEpression in patients with Coronary ARtery Disease (DECARD) trial. Journal of cardiovascular pharmacology. vol 60. issue 4. 2013-03-19. PMID:22820898. |
selective serotonin reuptake inhibitors are commonly used for treatment of depression in patients with cardiac diseases. |
2013-03-19 |
2023-08-12 |
Not clear |
| Jonathan P Roiser, Jamey Levy, Stephen J Fromm, David Goldman, Colin A Hodgkinson, Gregor Hasler, Barbara J Sahakian, Wayne C Drevet. Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers. Journal of psychopharmacology (Oxford, England). vol 26. issue 11. 2013-03-18. PMID:22495688. |
serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers. |
2013-03-18 |
2023-08-12 |
human |
| Jonathan P Roiser, Jamey Levy, Stephen J Fromm, David Goldman, Colin A Hodgkinson, Gregor Hasler, Barbara J Sahakian, Wayne C Drevet. Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers. Journal of psychopharmacology (Oxford, England). vol 26. issue 11. 2013-03-18. PMID:22495688. |
previous studies have suggested that polymorphism in the serotonin transporter gene (5-httlpr) influences responses to serotonergic manipulation, with opposite effects in patients recovered from depression (rmdd) and controls. |
2013-03-18 |
2023-08-12 |
human |
| Chad E Beyer, Zoë A Hughe. Innovations in CNS drug discovery: differentiating strategies to treat depression. Expert opinion on drug discovery. vol 2. issue 10. 2013-03-17. PMID:23484532. |
over the past two decades, the clinical management of depression has been revolutionized by the introduction of selective serotonin re-uptake inhibitors and serotonin/noradrenaline re-uptake inhibitors. |
2013-03-17 |
2023-08-12 |
Not clear |
| Feng-Li An, Shu-Cheng A. [Orbitofrontal cortex action of 5-hydroxytryptamine, glutamate and nitric oxide in an acute forced swimming stress-induced depression model]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 27. issue 4. 2013-03-14. PMID:22295529. |
[orbitofrontal cortex action of 5-hydroxytryptamine, glutamate and nitric oxide in an acute forced swimming stress-induced depression model]. |
2013-03-14 |
2023-08-12 |
Not clear |
| Verner Knott, Andrea Thompson, Dhrasti Shah, Vadim Ilivitsk. Neural expression of nicotine's antidepressant properties during tryptophan depletion: an EEG study in healthy volunteers at risk for depression. Biological psychology. vol 91. issue 2. 2013-03-14. PMID:22743591. |
this randomized, double-blind study in 20 healthy volunteers with a positive family history of depression examined the effects of transdermal nicotine on mood and eeg changes accompanying transient reductions in serotonin induced by acute tryptophan depletion (atd). |
2013-03-14 |
2023-08-12 |
human |
| Verner Knott, Andrea Thompson, Dhrasti Shah, Vadim Ilivitsk. Neural expression of nicotine's antidepressant properties during tryptophan depletion: an EEG study in healthy volunteers at risk for depression. Biological psychology. vol 91. issue 2. 2013-03-14. PMID:22743591. |
these findings indicate that in depression prone individuals, nicotine acts to stabilize the mood lowering and associated frontal functional asymmetry elicited by an acute decrease in brain serotonin. |
2013-03-14 |
2023-08-12 |
human |
| Magdalena Bosak, Dominika Dudek, Marcin Siwe. [Depression in patients with epilepsy]. Psychiatria polska. vol 46. issue 5. 2013-03-14. PMID:23394027. |
comorbid depression in epilepsy affects negatively the health-related quality of life, increases suicide risk and costs of medical care when compared to patients without depression selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitor are first-line treatment of depression in patients with epilepsy. |
2013-03-14 |
2023-08-12 |
Not clear |
| b' G\\xc3\\xb6rkem Karaka\\xc5\\x9f U\\xc4\\x9furlu, Sinay Onen, Deniz Bay\\xc4\\xb1nd\\xc4\\xb1rl\\xc4\\xb1, Ali Cayk\\xc3\\xb6yl\\xc3\\xb. Acute dystonia after using single dose duloxetine: case report. Psychiatry investigation. vol 10. issue 1. 2013-03-14. PMID:23483133.' |
duloxetine is a balanced and potent serotonin and noradrenaline reuptake inhibitor which is known to be effective in depression and anxiety disorders. |
2013-03-14 |
2023-08-12 |
Not clear |