| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Stockmeie. Neurobiology of serotonin in depression and suicide. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616801. |
although there were no significant differences between suicide victims with major depression and psychiatrically normal control subjects in serotonin-1a or serotonin-2a receptors in the right prefrontal cortex (area 10) or the hippocampus, there were region-specific alterations in suicide victims with major depression in g-protein-induced activation of the phosphoinositide signal transduction system and in the levels of g-protein alpha subunits involved in cyclic amp synthesis. |
1998-06-24 |
2023-08-12 |
human |
| G Rajkowsk. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616803. |
neurochemical studies demonstrate altered numbers of monoaminergic receptors in the prefrontal cortex in suicide and depression victims, implicating dysfunction of the prefrontal cortex in the neuropathology of suicide and psychiatric disorders. |
1998-06-24 |
2023-08-12 |
human |
| G Rajkowsk. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Annals of the New York Academy of Sciences. vol 836. 1998-06-24. PMID:9616803. |
in another population of suicide victims with major depression (nonpsychotic), further morphopathological differences from scz and similarities to bipolar disorder were observed in the prefrontal cortex. |
1998-06-24 |
2023-08-12 |
human |
| J N Joyce, S G Goldsmith, E V Gurevic. Limbic circuits and monoamine receptors: dissecting the effects of antipsychotics from disease processes. Journal of psychiatric research. vol 31. issue 2. 1997-10-23. PMID:9278186. |
the limbic loop interconnecting the pfc and ventral striatum may be the site of antipsychotic regulation of certain symptoms in schizophrenia, particularly anhedonia and depression. |
1997-10-23 |
2023-08-12 |
Not clear |
| V Geller, N Grisaru, J M Abarbanel, T Lemberg, R H Belmake. Slow magnetic stimulation of prefrontal cortex in depression and schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 1. 1997-06-27. PMID:9075260. |
slow magnetic stimulation of prefrontal cortex in depression and schizophrenia. |
1997-06-27 |
2023-08-12 |
Not clear |
| G Flügge, O Ahrens, E Fuch. Monoamine receptors in the prefrontal cortex of Tupaia belangeri during chronic psychosocial stress. Cell and tissue research. vol 288. issue 1. 1997-06-20. PMID:9042767. |
the prefrontal cortex has been reported to be involved in the regulation of emotional behaviour by integrating cognitive, emotional and autonomic information processes, and impairments of its functions are implicated in psychopathologies such as depression. |
1997-06-20 |
2023-08-12 |
Not clear |
| J D Bremner, R B Innis, R M Salomon, L H Staib, C K Ng, H L Miller, R A Bronen, J H Krystal, J Duncan, D Rich, L H Price, R Malison, H Dey, R Soufer, D S Charne. Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Archives of general psychiatry. vol 54. issue 4. 1997-04-25. PMID:9107153. |
positron emission tomography and single photon emission computed tomography studies implicated the dorsolateral prefrontal cortex, orbitofrontal cortex, thalamus, and caudate nucleus in the pathogenesis of depression. |
1997-04-25 |
2023-08-12 |
Not clear |
| C A Stockmeier, G E Dilley, L A Shapiro, J C Overholser, P A Thompson, H Y Meltze. Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 2. 1997-04-15. PMID:9015799. |
there were no significant differences between suicide victims with major depression and comparison subjects in 5-ht1a or 5-ht2a receptors in area 10 of the right prefrontal cortex or the hippocampus. |
1997-04-15 |
2023-08-12 |
human |
| C A Stockmeier, G E Dilley, L A Shapiro, J C Overholser, P A Thompson, H Y Meltze. Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 2. 1997-04-15. PMID:9015799. |
the current results suggest that the number of 5-ht1a and 5-ht2a receptors in the right prefrontal cortex (area 10) or hippocampus are not different in suicide victims with major depression. |
1997-04-15 |
2023-08-12 |
human |
| H Ito, R Kawashima, S Awata, S Ono, K Sato, R Goto, M Koyama, M Sato, H Fukud. Hypoperfusion in the limbic system and prefrontal cortex in depression: SPECT with anatomic standardization technique. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 37. issue 3. 1997-01-06. PMID:8772633. |
hypoperfusion in the limbic system and prefrontal cortex in depression: spect with anatomic standardization technique. |
1997-01-06 |
2023-08-12 |
Not clear |
| M A Pacheco, C Stockmeier, H Y Meltzer, J C Overholser, G E Dilley, R S Jop. Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813380. |
the function of the phosphoinositide signal transduction system and the levels of heterotrimeric g-protein alpha-subunits were examined in postmortem prefrontal cortex regions (8/9) and region (10) from suicide victims with major depression and matched control subjects without psychiatric illness. |
1996-12-03 |
2023-08-12 |
human |
| M A Pacheco, C Stockmeier, H Y Meltzer, J C Overholser, G E Dilley, R S Jop. Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813380. |
these results demonstrate that in the prefrontal cortex of suicide victims with major depression compared to normal control subjects there is a region-specific alteration of g-protein-induced activation of the phosphoinositide signal transduction system and in the levels of g-protein alpha-subunits involved in cyclic amp synthesis. |
1996-12-03 |
2023-08-12 |
human |
| b' A Pascual-Leone, B Rubio, F Pallard\\xc3\\xb3, M D Catal\\xc3\\xa. Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. Lancet (London, England). vol 348. issue 9022. 1996-08-22. PMID:8684201.' |
rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. |
1996-08-22 |
2023-08-12 |
human |
| O Moreaud, B Naegele, J P Chabannes, J L Roulin, B Garbolino, J Pella. [Frontal lobe dysfunction and depressive state: relation to endogenous character of depression]. L'Encephale. vol 22. issue 1. 1996-08-19. PMID:8681875. |
a dysfunction of dorsolateral prefrontal cortex (dlpf) in major depression is suggested by functional imagery and comparative neuropsychology. |
1996-08-19 |
2023-08-12 |
human |
| M S George, E M Wassermann, W A Williams, A Callahan, T A Ketter, P Basser, M Hallett, R M Pos. Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. Neuroreport. vol 6. issue 14. 1996-02-22. PMID:8547583. |
converging evidence points to hypofunction of the left prefrontal cortex in depression. |
1996-02-22 |
2023-08-12 |
human |
| C J Bench, R S Frackowiak, R J Dola. Changes in regional cerebral blood flow on recovery from depression. Psychological medicine. vol 25. issue 2. 1995-10-17. PMID:7675913. |
we have previously described focal abnormalities of regional cerebral blood flow (rcbf) in the left dorsolateral prefrontal cortex (dlpfc), anterior cingulate cortex and angular gyrus in 40 patients with major depression. |
1995-10-17 |
2023-08-12 |
Not clear |
| C Trichard, J L Martinot, M Alagille, M C Masure, P Hardy, D Ginestet, A Félin. Time course of prefrontal lobe dysfunction in severely depressed in-patients: a longitudinal neuropsychological study. Psychological medicine. vol 25. issue 1. 1995-07-24. PMID:7792365. |
vft impairment is consistent with the hypothesis of a left prefrontal cortex dysfunction in depression. |
1995-07-24 |
2023-08-12 |
Not clear |
| R J Dolan, C J Bench, P F Liddle, K J Friston, C D Frith, P M Grasby, R S Frackowia. Dorsolateral prefrontal cortex dysfunction in the major psychoses; symptom or disease specificity? Journal of neurology, neurosurgery, and psychiatry. vol 56. issue 12. 1994-01-31. PMID:8270929. |
neurophysiological deficits in the left dorsolateral prefrontal cortex (dlpfc) have been described in positron emission tomography studies of schizophrenia and depression. |
1994-01-31 |
2023-08-12 |
human |
| K M Yazici, O Kapucu, B Erbas, E Varoglu, C Gülec, C F Bekdi. Assessment of changes in regional cerebral blood flow in patients with major depression using the 99mTc-HMPAO single photon emission tomography method. European journal of nuclear medicine. vol 19. issue 12. 1993-01-21. PMID:1464356. |
the severity of depression is correlated with the reduction in cbf in the regions of the anterofrontal and left prefrontal cortex. |
1993-01-21 |
2023-08-11 |
human |
| M Mintz, L Reyneke, A de Villiers, R Allin, V Russell, W Daniels, G van der Spuy, A Jaffer, L Kellaway, R Dougla. Effect of amygdaloid kindling on [3H]dopamine and [14C]acetylcholine release from rat prefrontal cortex and striatal slices. Brain research. vol 592. issue 1-2. 1993-01-06. PMID:1450903. |
long-term effects of kindling consisted of facilitation of ach release in the ventral striatum contralateral to the kindled amygdala and bilateral depression of da release in the prefrontal cortex. |
1993-01-06 |
2023-08-11 |
rat |