| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jessica Mingardi, Luca La Via, Paolo Tornese, Giulia Carini, Kalevi Trontti, Mara Seguini, Daniela Tardito, Federica Bono, Chiara Fiorentini, Leonardo Elia, Iiris Hovatta, Maurizio Popoli, Laura Musazzi, Alessandro Barbo. miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine. Neurobiology of stress. vol 15. 2021-08-31. PMID:34458512. |
on the other hand, the rapid antidepressant effect of acute ketamine is consistently reported to occur together with the rescue of dendritic atrophy and reduction of spine number induced by chronic stress in the hippocampus and prefrontal cortex of animal models of depression. |
2021-08-31 |
2023-08-13 |
rat |
| Keaton A Unroe, Matthew E Glover, Elizabeth A Shupe, Ningping Feng, Sarah M Clinto. Perinatal SSRI Exposure Disrupts G Protein-coupled Receptor BAI3 in Developing Dentate Gyrus and Adult Emotional Behavior: Relevance to Psychiatric Disorders. Neuroscience. vol 471. 2021-08-25. PMID:34293414. |
to determine translational implications of this work, we examined expression of bai3 and related molecules in hippocampus and prefrontal cortex from patients that suffered with depression or schizophrenia relative to healthy control subjects. |
2021-08-25 |
2023-08-13 |
human |
| Wenjuan Wang, Yong Qiao, Huiying Qu, Lin Zhu, Linlin Mu, Chunyue Li, Jie Fang, Hong Lia. The protective role of Neuregulin1-ErbB4 signaling in a chronic social defeat stress model. Neuroreport. vol 31. issue 9. 2021-08-18. PMID:32427713. |
brain structural mri and postmortem studies on patients with depression have revealed changes in the anatomy and functionality in various brain regions, including the amygdala, thalamus, hippocampus, and prefrontal cortex (pfc). |
2021-08-18 |
2023-08-13 |
mouse |
| Naofumi Kajitani, Masaaki Iwata, Akihiko Miura, Kyohei Tsunetomi, Takehiko Yamanashi, Ryoichi Matsuo, Tsuyoshi Nishiguchi, Saki Fukuda, Mayu Nagata, Midori Shibushita, Takahira Yamauchi, Shenghong Pu, Yukihiko Shirayama, Ken Watanabe, Koichi Kanek. Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression. Neuropsychopharmacology reports. vol 40. issue 2. 2021-08-16. PMID:32125791. |
prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous nlrp3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression. |
2021-08-16 |
2023-08-13 |
Not clear |
| Lilla Ravasz, Katalin Adrienna Kékesi, Dániel Mittli, Mihail Ivilinov Todorov, Zsolt Borhegyi, Mária Ercsey-Ravasz, Botond Tyukodi, Jinhui Wang, Tamás Bártfai, James Eberwine, Gábor Juhás. Cell Surface Protein mRNAs Show Differential Transcription in Pyramidal and Fast-Spiking Cells as Revealed by Single-Cell Sequencing. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 2. 2021-08-11. PMID:32710103. |
the prefrontal cortex (pfc) plays a key role in higher order cognitive functions and psychiatric disorders such as autism, schizophrenia, and depression. |
2021-08-11 |
2023-08-13 |
mouse |
| Chi-Wei Lee, Han-Fang Wu, Ming-Chia Chu, Yueh-Jung Chung, Wei-Chang Mao, Cheng-Ta Li, Hui-Ching Li. Mechanism of Intermittent Theta-Burst Stimulation in Synaptic Pathology in the Prefrontal Cortex in an Antidepressant-Resistant Depression Rat Model. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 1. 2021-08-11. PMID:32901273. |
mechanism of intermittent theta-burst stimulation in synaptic pathology in the prefrontal cortex in an antidepressant-resistant depression rat model. |
2021-08-11 |
2023-08-13 |
rat |
| Chi-Wei Lee, Han-Fang Wu, Ming-Chia Chu, Yueh-Jung Chung, Wei-Chang Mao, Cheng-Ta Li, Hui-Ching Li. Mechanism of Intermittent Theta-Burst Stimulation in Synaptic Pathology in the Prefrontal Cortex in an Antidepressant-Resistant Depression Rat Model. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 1. 2021-08-11. PMID:32901273. |
the results showed that itbs treatment improved not only the impaired ltp, but also the aberrant long-term depression in the pfc of antidepressant-resistant depression model rats. |
2021-08-11 |
2023-08-13 |
rat |
| Yi-Fei Wang, Yu Wang, Yue Zhang, Xiao Guo, Xun He, Jin-Ling Zhang, Pei-Jing Ron. [Effect of transcutaneous auricular vagus nerve stimulation on the expression of TLR4、MyD88、IL-18 protein in the prefrontal cortex of depression rats]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 7. 2021-08-10. PMID:34369678. |
[effect of transcutaneous auricular vagus nerve stimulation on the expression of tlr4、myd88、il-18 protein in the prefrontal cortex of depression rats]. |
2021-08-10 |
2023-08-13 |
rat |
| Ting Yang, Bangli Shen, Aiqin Wu, Xinglu Tang, Wei Chen, Zhenzhong Zhang, Bo Chen, Zhongwei Guo, Xiaozheng Li. Abnormal Functional Connectivity of the Amygdala in Mild Cognitive Impairment Patients With Depression Symptoms Revealed by Resting-State fMRI. Frontiers in psychiatry. vol 12. 2021-08-03. PMID:34335316. |
these results suggest that the dysfunction of the amygdala-medial prefrontal cortex network and the amygdala-sensorimotor network might be involved in the neural mechanism underlying depression in mci. |
2021-08-03 |
2023-08-13 |
Not clear |
| Lu Tian, Juncai Pu, Yiyun Liu, Siwen Gui, Xiaogang Zhong, Xuemian Song, Shaohua Xu, Hanpin Zhang, Haiyang Wang, Wei Zhou, Peng Xi. Metabolomic analysis of animal models of depression. Metabolic brain disease. vol 35. issue 6. 2021-07-29. PMID:32440806. |
previous studies have shown that the prefrontal cortex (pfc) is among most important brain regions that exhibits metabolic changes in depression. |
2021-07-29 |
2023-08-13 |
Not clear |
| Lu Tian, Juncai Pu, Yiyun Liu, Siwen Gui, Xiaogang Zhong, Xuemian Song, Shaohua Xu, Hanpin Zhang, Haiyang Wang, Wei Zhou, Peng Xi. Metabolomic analysis of animal models of depression. Metabolic brain disease. vol 35. issue 6. 2021-07-29. PMID:32440806. |
a comprehensive analysis based on candidate metabolites in the pfc of animal models of depression will provide valuable information for understanding the pathogenic mechanism underlying depression. |
2021-07-29 |
2023-08-13 |
Not clear |
| Xiaoyan Li, Xi Su, Jiewei Liu, Huijuan Li, Ming Li, Wenqiang Li, Xiong-Jian Lu. Transcriptome-wide association study identifies new susceptibility genes and pathways for depression. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34021117. |
here, we perform a transcriptome-wide association study (twas) of depression by integrating gwas summary statistics from 807,553 individuals (246,363 depression cases and 561,190 controls) and summary-level gene-expression data (from the dorsolateral prefrontal cortex (dlpfc) of 1003 individuals). |
2021-07-14 |
2023-08-13 |
Not clear |
| Pravin Kumar Mishra, Madhavi Adusumilli, Pallavi Deolal, Graeme F Mason, Arvind Kumar, Anant Bahadur Pate. Impaired neuronal and astroglial metabolic activity in chronic unpredictable mild stress model of depression: Reversal of behavioral and metabolic deficit with lanicemine. Neurochemistry international. vol 137. 2021-07-09. PMID:32360130. |
here, we evaluated neural metabolic activity in prefrontal cortex (pfc) in c57bl6 mice undergoing a chronic unpredictable mild stress (cums) for three weeks to induce depression. |
2021-07-09 |
2023-08-13 |
mouse |
| Mehdi Rezaei, Mohammad Mahdi Shariat Bagheri, Mehdi Ahmad. Clinical and demographic predictors of response to anodal tDCS treatment in major depression disorder (MDD). Journal of psychiatric research. vol 138. 2021-07-05. PMID:33831679. |
transcranial direct current stimulation (tdcs) of the prefrontal cortex is known as a promising intervention in major depression disorder (mdd). |
2021-07-05 |
2023-08-13 |
Not clear |
| R Bodén, J Bengtsson, E Thörnblom, W Struckmann, J Persso. Dorsomedial prefrontal theta burst stimulation to treat anhedonia, avolition, and blunted affect in schizophrenia or depression - a randomized controlled trial. Journal of affective disorders. vol 290. 2021-07-05. PMID:34020205. |
intermittent theta burst stimulation (itbs) over the dorsomedial prefrontal cortex (dmpfc) has shown promise in open-label trials of depression. |
2021-07-05 |
2023-08-13 |
Not clear |
| Arshad Ghaffari-Nasab, Reza Badalzadeh, Gisou Mohaddes, Mohammad Reza Alipou. Young plasma administration mitigates depression-like behaviours in chronic mild stress-exposed aged rats by attenuating apoptosis in prefrontal cortex. Experimental physiology. vol 106. issue 7. 2021-07-01. PMID:34018261. |
following chronic transfusion of young plasma, depressive behaviour was improved in the depression model of aged rats, which was associated with reduced apoptosis process in the prefrontal cortex. |
2021-07-01 |
2023-08-13 |
rat |
| Toya Okonogi, Takuya Sasak. Theta-Range Oscillations in Stress-Induced Mental Disorders as an Oscillotherapeutic Target. Frontiers in behavioral neuroscience. vol 15. 2021-06-29. PMID:34177486. |
here, we review recent observations from rodents demonstrating how neuronal oscillations in the hippocampus, amygdala, and prefrontal cortex are engaged in emotional behavior and altered by psychiatric changes such as anxiety and depression. |
2021-06-29 |
2023-08-13 |
Not clear |
| Ronald S Duman, Satoshi Deyama, Manoela Viar Fogaç. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31811669. |
this work demonstrates that stress and depression are associated with atrophy of neurons and reduced synaptic connectivity in brain regions such as the hippocampus and prefrontal cortex that contribute to depressive behaviors, and conversely that antidepressant treatment can reverse these deficits. |
2021-06-28 |
2023-08-13 |
Not clear |
| Ronald S Duman, Satoshi Deyama, Manoela Viar Fogaç. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31811669. |
here, we review the literature demonstrating that exposure to stress and depression decreases bdnf expression in the hippocampus and pfc and conversely that antidepressant treatment can up-regulate bdnf in the adult brain and reverse the effects of stress. |
2021-06-28 |
2023-08-13 |
Not clear |
| Mayank S Jog, Elizabeth Kim, Cole Anderson, Antoni Kubicki, Rishikesh Kayathi, Kay Jann, Lirong Yan, Amber Leaver, Gerhard Hellemann, Marco Iacoboni, Roger P Woods, Danny J J Wang, Katherine L Nar. In-vivo imaging of targeting and modulation of depression-relevant circuitry by transcranial direct current stimulation: a randomized clinical trial. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33627624. |
depressed participants (n = 66, baseline hamilton depression rating scale (hdrs) 17-item scores ≥14 and <24) were randomized into active/sham and high-definition (hd)/conventional (conv) tdcs groups using a double-blind, parallel design, and received tdcs individually targeted at the left dorsolateral prefrontal cortex (dlpfc). |
2021-06-28 |
2023-08-13 |
human |