| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mandakh Bekhbat, Michael T Treadway, Jennifer C Felge. Inflammation as a Pathophysiologic Pathway to Anhedonia: Mechanisms and Therapeutic Implications. Current topics in behavioral neurosciences. 2021-12-31. PMID:34971449. |
consistent with laboratory studies involving exogenous administration of peripheral inflammatory stimuli, neuroimaging studies have further confirmed that increased endogenous inflammation in depression is associated with decreased activation of and reduced functional connectivity within reward circuits involving ventral striatum and ventromedial prefrontal cortex in association with anhedonia. |
2021-12-31 |
2023-08-13 |
Not clear |
| Mengge Bai, Heming Yu, Chong Chen, Xingzhe Xu, Yong He, Yue Wang, Yu Tian, Zhonghao Wu, Tianlan Lan, Yan Li, Xiangyu Chen, Zhi Chen, Libo Zhao, Liang Fang, Deyu Yang, Ke Cheng, Peng Xi. Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex. Neuroscience letters. 2021-12-29. PMID:34965441. |
western blotting validated that the pedf expression in the pfc was downregulated in the mouse chronic social defeat stress and rat chronic unpredictable mild stress models of depression. |
2021-12-29 |
2023-08-13 |
mouse |
| Mengge Bai, Heming Yu, Chong Chen, Xingzhe Xu, Yong He, Yue Wang, Yu Tian, Zhonghao Wu, Tianlan Lan, Yan Li, Xiangyu Chen, Zhi Chen, Libo Zhao, Liang Fang, Deyu Yang, Ke Cheng, Peng Xi. Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex. Neuroscience letters. 2021-12-29. PMID:34965441. |
combined with the above findings, this provides an insight into a potential mechanism of the antidepressant effects of pedf via the pfc, which may help to improve understanding of depression pathophysiology. |
2021-12-29 |
2023-08-13 |
mouse |
| Diego A Pizzagalli, Angela C Robert. Prefrontal cortex and depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 47. issue 1. 2021-12-12. PMID:34341498. |
prefrontal cortex and depression. |
2021-12-12 |
2023-08-13 |
Not clear |
| Shun Aoki, Satoshi Deyama, Rinako Sugie, Kohei Ishimura, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaned. The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34801580. |
and intra-medial prefrontal cortex (mpfc) infusions of rve1 produce antidepressant-like effects in a lipopolysaccharide-induced depression mouse model. |
2021-12-11 |
2023-08-13 |
mouse |
| V A Cardenas, J V Bhat, A M Horwege, T J Ehrlich, J Lavacot, D H Mathalon, G H Glover, B J Roach, B W Badran, S D Forman, M S George, M E Thase, J A Yesavage, D Yurgelun-Todd, A C Rose. Anatomical and fMRI-network comparison of multiple DLPFC targeting strategies for repetitive transcranial magnetic stimulation treatment of depression. Brain stimulation. vol 15. issue 1. 2021-12-10. PMID:34767967. |
the efficacy of repetitive transcranial magnetic stimulation (rtms) for depression may vary depending on the subregion stimulated within the dorsolateral prefrontal cortex (dlpfc). |
2021-12-10 |
2023-08-13 |
Not clear |
| Oktay Genel, Carmine M Pariante, Alessandra Borsin. The role of AQP4 in the pathogenesis of depression, and possible related mechanisms. Brain, behavior, and immunity. vol 98. 2021-12-09. PMID:34474133. |
while in post-mortem and ex vivo studies of depression aqp4 expression was usually decreased in the hippocampus, prefrontal cortex and locus coeruleus, in clinical studies, where mrna aqp4 expression or serum aqp4 autoantibodies were measured, there were no differences in depressed patients when compared with controls. |
2021-12-09 |
2023-08-13 |
Not clear |
| Lipeng Ning, Yogesh Rathi, Tracy Barbour, Nikos Makris, Joan A Camprodo. White matter markers and predictors for subject-specific rTMS response in major depressive disorder. Journal of affective disorders. 2021-12-07. PMID:34875281. |
we defined disease-relevant fiber bundles connected to different subregions of the left prefrontal cortex and analyzed changes in diffusion properties as well as correlations between the changes of dmri measures and the changes in hamilton depression rating scale (hamd). |
2021-12-07 |
2023-08-13 |
Not clear |
| Alice Morgunova, Cecilia Flore. MicroRNA regulation of prefrontal cortex development and psychiatric risk in adolescence. Seminars in cell & developmental biology. vol 118. 2021-12-01. PMID:33933350. |
we highlight that altered levels of micrornas in the pfc are associated with psychopathologies of adolescent onset, notably depression and schizophrenia. |
2021-12-01 |
2023-08-13 |
Not clear |
| Toshiyuki Ohtani, Akio Wakabayashi, Chihiro Sutoh, Fumiyo Oshima, Yoshiyuki Hirano, Eiji Shimiz. Ventrolateral prefrontal hemodynamic responses in autism spectrum disorder with and without depression. PloS one. vol 16. issue 8. 2021-12-01. PMID:34449833. |
the asd group, including both of the asd with and asd without depression groups, showed smaller hemodynamic responses than the typical development group in portions of the left dorsolateral prefrontal cortex (dlpfc), bilateral ventrolateral prefrontal cortex (vlpfc) and anterior part of the temporal cortex (atc) during the vft. |
2021-12-01 |
2023-08-13 |
human |
| Diego A Pizzagalli, Angela C Robert. Correction: Prefrontal cortex and depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-11-26. PMID:34413479. |
correction: prefrontal cortex and depression. |
2021-11-26 |
2023-08-13 |
Not clear |
| Hong Li, Qiaoyan Song, Ruya Zhang, Youlong Zhou, Yazhuo Kon. Enhanced Temporal Coupling between Thalamus and Dorsolateral Prefrontal Cortex Mediates Chronic Low Back Pain and Depression. Neural plasticity. vol 2021. 2021-11-24. PMID:34659398. |
enhanced temporal coupling between thalamus and dorsolateral prefrontal cortex mediates chronic low back pain and depression. |
2021-11-24 |
2023-08-13 |
Not clear |
| Hong Li, Qiaoyan Song, Ruya Zhang, Youlong Zhou, Yazhuo Kon. Enhanced Temporal Coupling between Thalamus and Dorsolateral Prefrontal Cortex Mediates Chronic Low Back Pain and Depression. Neural plasticity. vol 2021. 2021-11-24. PMID:34659398. |
we found that (1) ldh patients had increased psychophysical disturbs (i.e., depression and anxiety), and depression (beck-depression inventory, bdi) was found to be an outstanding significant factor to predict chronic pain (short form of the mcgill pain questionnaire, sf-mpq); (2) the ldh group showed significantly smaller fractional anisotropy values in the region of posterior corona radiate while gray matter volumes were comparable in both groups; (3) resting state functional connectivity analysis revealed that ldh patients exhibited increased temporal coupling between the thalamus and dorsolateral prefrontal cortex (dlpfc), which further mediate the relationship from chronic pain to depression. |
2021-11-24 |
2023-08-13 |
Not clear |
| Hong Li, Qiaoyan Song, Ruya Zhang, Youlong Zhou, Yazhuo Kon. Enhanced Temporal Coupling between Thalamus and Dorsolateral Prefrontal Cortex Mediates Chronic Low Back Pain and Depression. Neural plasticity. vol 2021. 2021-11-24. PMID:34659398. |
our results emphasized that thalamic pathways underlying prefrontal cortex might play a key role in regulating chronic pain and depression of the pathophysiology of ldh. |
2021-11-24 |
2023-08-13 |
Not clear |
| Seneca N Ellis, Jennifer A Honeycut. Sex Differences in Affective Dysfunction and Alterations in Parvalbumin in Rodent Models of Early Life Adversity. Frontiers in behavioral neuroscience. vol 15. 2021-11-23. PMID:34803622. |
because anxiety and depression are thought to involve dysregulation in the balance of excitatory and inhibitory signaling in ela-vulnerable brain regions (e.g., prefrontal cortex, amygdala, hippocampus), outcomes are likely driven by alterations in local and/or circuit-specific inhibitory activity. |
2021-11-23 |
2023-08-13 |
Not clear |
| Alec J Jamieson, Ben J Harrison, Adeel Razi, Christopher G Dave. Rostral anterior cingulate network effective connectivity in depressed adolescents and associations with treatment response in a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-11-16. PMID:34782701. |
using spectral dynamic causal modelling, we examined the effective connectivity of the racc with eight other regions implicated in depression: the left and right anterior insular cortex (aic), amygdalae, and dorsolateral prefrontal cortex (dlpfc); and in the midline, the subgenual (sgacc) and dorsal anterior cingulate cortex (dacc). |
2021-11-16 |
2023-08-13 |
Not clear |
| Xiaoyan Li, Hongmei Wang, Chen Li, Jihong Wu, Jun Lu, Jian-You Guo, Ya T. Acupuncture inhibits NLRP3 inflammasome activation in the prefrontal cortex of a chronic stress rat model of depression. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 11. 2021-11-15. PMID:34636496. |
acupuncture inhibits nlrp3 inflammasome activation in the prefrontal cortex of a chronic stress rat model of depression. |
2021-11-15 |
2023-08-13 |
rat |
| Xiaoyan Li, Hongmei Wang, Chen Li, Jihong Wu, Jun Lu, Jian-You Guo, Ya T. Acupuncture inhibits NLRP3 inflammasome activation in the prefrontal cortex of a chronic stress rat model of depression. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 11. 2021-11-15. PMID:34636496. |
in this study, we investigated the effects of acupuncture treatment at the acupoints baihui (gv20) and yintang (gv29) on nlrp3 inflammasome in the prefrontal cortex (pfc) of an animal model of depression. |
2021-11-15 |
2023-08-13 |
rat |
| Suhyuk Chi, Minjae Song, Jong-Ha Lee, Minsoo Ko, Sang-Il Suh, Moon-Soo Le. Prospective study on resting state functional connectivity in adolescents with major depressive disorder after antidepressant treatment. Journal of psychiatric research. vol 142. 2021-10-29. PMID:34425489. |
previous studies have shown alterations between multiple brain areas, such as the prefrontal cortex, anterior cingulate cortex, and basal ganglia, but there are very few prospective studies with a longitudinal design on adolescent depression patients. |
2021-10-29 |
2023-08-13 |
Not clear |
| Wei Guo, Xi Xiao, Yu-Tao Tian, Jia-Jia Yan. [The role and mechanism of SIRT1 gene in depression]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 5. 2021-10-29. PMID:34708240. |
therefore, this review mainly summarizes the relevant research progress on the role and mechanism of sirt1 gene in the hippocampus, prefrontal cortex, amygdala, hypothalamic suprachiasmatic nucleus, and nucleus accumbens in depression, in order to provide new ideas for exploring the mechanism and prevention of depression. |
2021-10-29 |
2023-08-13 |
Not clear |