| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leah M Pyter, Sarah El Mouatassim Bih, Husain Sattar, Brian J Prendergas. Peripheral tumors alter neuroinflammatory responses to lipopolysaccharide in female rats. Brain research. vol 1552. 2014-10-16. PMID:24457042. |
), and expression of mrnas involved in the pathway linking inflammation and depression (interleukin-1beta [il-1β], cd11b, iκbα, indolamine 2,3-deoxygenase [ido]) was quantified by qpcr in the hippocampus, hypothalamus, and frontal cortex, 4 or 24h post-treatment. |
2014-10-16 |
2023-08-12 |
rat |
| Ewa Szczęsny, Joanna Slusarczyk, Katarzyna Głombik, Bogusława Budziszewska, Marta Kubera, Władysław Lasoń, Agnieszka Basta-Kai. Possible contribution of IGF-1 to depressive disorder. Pharmacological reports : PR. vol 65. issue 6. 2014-10-14. PMID:24553010. |
recent studies indicate that an impairment of synaptic plasticity in specific areas of the central nervous system (cns), particularly the hippocampus, may be an important factor in the pathogenesis of depression. |
2014-10-14 |
2023-08-12 |
Not clear |
| Anna Gądek-Michalska, Joanna Tadeusz, Paulina Rachwalska, Jan Bugajsk. Cytokines, prostaglandins and nitric oxide in the regulation of stress-response systems. Pharmacological reports : PR. vol 65. issue 6. 2014-10-14. PMID:24553014. |
during chronic stress-induced inhibition of systemic feedback, cytosolic glucocorticoid receptor (gr) levels were significantly changed in the prefrontal cortex (pfc) and hippocampus, both structures known to be deeply involved in the pathogenesis of depression. |
2014-10-14 |
2023-08-12 |
Not clear |
| Indira Tendolkar, Marleen van Beek, Iris van Oostrom, Marlies Mulder, Joost Janzing, Richard Oude Voshaar, Philip van Eijndhove. Electroconvulsive therapy increases hippocampal and amygdala volume in therapy refractory depression: a longitudinal pilot study. Psychiatry research. vol 214. issue 3. 2014-10-10. PMID:24090511. |
electroconvulsive therapy increases hippocampal and amygdala volume in therapy refractory depression: a longitudinal pilot study. |
2014-10-10 |
2023-08-12 |
human |
| Indira Tendolkar, Marleen van Beek, Iris van Oostrom, Marlies Mulder, Joost Janzing, Richard Oude Voshaar, Philip van Eijndhove. Electroconvulsive therapy increases hippocampal and amygdala volume in therapy refractory depression: a longitudinal pilot study. Psychiatry research. vol 214. issue 3. 2014-10-10. PMID:24090511. |
therefore, the aim of the present study was to investigate the effect of ect on hippocampus and amygdala volume in 15 antidepressant-free patients with treatment refractory depression (seven males, range 42-63 years). |
2014-10-10 |
2023-08-12 |
human |
| Zhi-heng Su, Hong-mei Jia, Hong-wu Zhang, Yu-Fei Feng, Lei An, Zhong-mei Zo. Hippocampus and serum metabolomic studies to explore the regulation of Chaihu-Shu-Gan-San on metabolic network disturbances of rats exposed to chronic variable stress. Molecular bioSystems. vol 10. issue 3. 2014-10-09. PMID:24398477. |
in the present work, metabolomic studies of biochemical changes in the hippocampus and serum of chronic variable stress (cvs)-induced depression rats after treatment with csgs were performed using ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (uplc-qtof-ms). |
2014-10-09 |
2023-08-12 |
rat |
| Zhi-heng Su, Hong-mei Jia, Hong-wu Zhang, Yu-Fei Feng, Lei An, Zhong-mei Zo. Hippocampus and serum metabolomic studies to explore the regulation of Chaihu-Shu-Gan-San on metabolic network disturbances of rats exposed to chronic variable stress. Molecular bioSystems. vol 10. issue 3. 2014-10-09. PMID:24398477. |
a total of twenty-six metabolites (16 from the hippocampus and 10 from serum) were considered as potential biomarkers involved in the development of depression. |
2014-10-09 |
2023-08-12 |
rat |
| Peter Rotheneichner, Simona Lange, Anna O'Sullivan, Julia Marschallinger, Pia Zaunmair, Christian Geretsegger, Ludwig Aigner, Sebastien Couillard-Despre. Hippocampal neurogenesis and antidepressive therapy: shocking relations. Neural plasticity. vol 2014. 2014-10-06. PMID:24967107. |
speculations on the involvement of hippocampal neurogenesis, a form of neuronal plasticity, in the aetiology of depression and the mode of action of antidepressive therapies, started to arise more than a decade ago. |
2014-10-06 |
2023-08-13 |
mouse |
| Jie Luo, Su Min, Ke Wei, Jun Cao, Bin Wang, Ping Li, Jun Dong, Yuanyuan Li. Propofol prevents electroconvulsive-shock-induced memory impairment through regulation of hippocampal synaptic plasticity in a rat model of depression. Neuropsychiatric disease and treatment. vol 10. 2014-10-06. PMID:25285008. |
propofol prevents electroconvulsive-shock-induced memory impairment through regulation of hippocampal synaptic plasticity in a rat model of depression. |
2014-10-06 |
2023-08-13 |
rat |
| Y Kunii, T M Hyde, T Ye, C Li, B Kolachana, D Dickinson, D R Weinberger, J E Kleinman, B K Lipsk. Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder and genetic associations with t-DARPP-32 expression. Molecular psychiatry. vol 19. issue 2. 2014-10-01. PMID:23295814. |
in this study, we examined the association of expression of two major darpp-32 transcripts, full-length (fl-darpp-32) and truncated (t-darpp-32), with genetic variants of darpp-32 in three brain regions receiving dopaminergic input and implicated in schizophrenia (the dorsolateral prefrontal cortex (dlpfc), hippocampus and caudate) in a much larger set of postmortem samples from patients with schizophrenia, bipolar disorder, major depression and normal controls (>700 subjects). |
2014-10-01 |
2023-08-12 |
human |
| Martine Elbejjani, Rebecca Fuhrer, Michal Abrahamowicz, Bernard Mazoyer, Fabrice Crivello, Christophe Tzourio, Carole Dufoui. Hippocampal atrophy and subsequent depressive symptoms in older men and women: results from a 10-year prospective cohort. American journal of epidemiology. vol 180. issue 4. 2014-09-29. PMID:25086051. |
several studies have reported smaller hippocampal volume in patients with depression. |
2014-09-29 |
2023-08-13 |
human |
| Martine Elbejjani, Rebecca Fuhrer, Michal Abrahamowicz, Bernard Mazoyer, Fabrice Crivello, Christophe Tzourio, Carole Dufoui. Hippocampal atrophy and subsequent depressive symptoms in older men and women: results from a 10-year prospective cohort. American journal of epidemiology. vol 180. issue 4. 2014-09-29. PMID:25086051. |
one hypothesis is that hippocampal atrophy might be a susceptibility factor for depression. |
2014-09-29 |
2023-08-13 |
human |
| K Sakata, S M Duk. Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus. Neuroscience. vol 260. 2014-09-25. PMID:24345476. |
mrna levels were measured in the frontal cortex and hippocampus, which are regions related to depression and schizophrenia and where promoter iv is active. |
2014-09-25 |
2023-08-12 |
mouse |
| Takeshi Onoue, Hiroyuki Toda, Yukiei Naka. [Childhood stress and depression]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 33. issue 3. 2014-09-25. PMID:25069243. |
several studies of major depression reported that childhood stress or abuse increases the hypothalamic-pituitary-adrenal axis function and is related to low volume of the hippocampus and anterior cingulate. |
2014-09-25 |
2023-08-13 |
Not clear |
| Xi Jin, Yidan Zhang, Qiaoying Li, Jianjun Zha. Mechanisms underlying the beneficial effects of Kaiyu Granule for depression. Neural regeneration research. vol 8. issue 34. 2014-09-10. PMID:25206645. |
these results suggested that kaiyu granule improved depression by affecting g-protein-coupled inwardly rectifying k(+) channel 1 expression in the rat hippocampus. |
2014-09-10 |
2023-08-13 |
rat |
| Dongmei Duan, Xiuyan Yang, Tu Ya, Liping Che. Hippocampal gene expression in a rat model of depression after electroacupuncture at the Baihui and Yintang acupoints. Neural regeneration research. vol 9. issue 1. 2014-09-10. PMID:25206746. |
hippocampal gene expression in a rat model of depression after electroacupuncture at the baihui and yintang acupoints. |
2014-09-10 |
2023-08-13 |
rat |
| Hao Guo, Chen Cheng, Xiaohua Cao, Jie Xiang, Junjie Chen, Kerang Zhan. Resting-state functional connectivity abnormalities in first-onset unmedicated depression. Neural regeneration research. vol 9. issue 2. 2014-09-10. PMID:25206796. |
in addition, right hippocampus and right thalamus were closely linked with the severity of depression. |
2014-09-10 |
2023-08-13 |
Not clear |
| Zhicheng Chen, Cherry Xiong, Cassandra Pancyr, Jocelyn Stockwell, Wolfgang Walz, Francisco S Cayabya. Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin-mediated AMPA receptor endocytosis and long-lasting synaptic inhibition in rat hippocampal CA3-CA1 synapses: differential regulation of GluA2 and GluA1 subunits by p38 MAPK and JNK. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 29. 2014-09-05. PMID:25031403. |
prolonged stimulation of a1rs with the agonist n(6)-cyclopentyladenosine (cpa) caused adenosine-induced persistent synaptic depression (apsd) in hippocampal brain slices, and apsd levels were blunted by inhibiting clathrin-mediated endocytosis of glua2 subunits with the tat-glua2-3y peptide. |
2014-09-05 |
2023-08-13 |
rat |
| Zhicheng Chen, Cherry Xiong, Cassandra Pancyr, Jocelyn Stockwell, Wolfgang Walz, Francisco S Cayabya. Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin-mediated AMPA receptor endocytosis and long-lasting synaptic inhibition in rat hippocampal CA3-CA1 synapses: differential regulation of GluA2 and GluA1 subunits by p38 MAPK and JNK. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 29. 2014-09-05. PMID:25031403. |
finally, in a pial vessel disruption cortical stroke model, a unilateral cortical lesion compared with sham surgery reduced hippocampal glua2, glua1, and a1r surface expression and also caused synaptic depression in hippocampal slices that was consistent with ampar downregulation and decreased probability of transmitter release. |
2014-09-05 |
2023-08-13 |
rat |
| Zhicheng Chen, Cherry Xiong, Cassandra Pancyr, Jocelyn Stockwell, Wolfgang Walz, Francisco S Cayabya. Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin-mediated AMPA receptor endocytosis and long-lasting synaptic inhibition in rat hippocampal CA3-CA1 synapses: differential regulation of GluA2 and GluA1 subunits by p38 MAPK and JNK. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 29. 2014-09-05. PMID:25031403. |
together, these results indicate a previously unknown mechanism for a1r-induced persistent synaptic depression involving clathrin-mediated glua2 and glua1 internalization that leads to hippocampal neurodegeneration after hypoxia/cerebral ischemia. |
2014-09-05 |
2023-08-13 |
rat |