| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohd Tayyab, Mehdi H Shahi, Shirin Farheen, Mubeena Mariyath P M, Nabeela Khanam, M Mobarak Hossai. Exploring the potential role of sonic hedgehog cell signalling pathway in antidepressant effects of nicotine in chronic unpredictable mild stress rat model. Heliyon. vol 5. issue 5. 2020-09-30. PMID:31193084. |
our investigations showed that chronic unpredictable mild stress induced depression results declined expression of bdnf, wnt/β-catenin, shh and its downstream transcription factors gli1/2/3 and nkx2.2 in the hippocampus of male wistar rat. |
2020-09-30 |
2023-08-13 |
rat |
| b' Bianca Besteher, Letizia Squarcina, Robert Spalthoff, Marcella Bellani, Christian Gaser, Paolo Brambilla, Igor Nenadi\\xc4\\x8. Hippocampal Volume as a Putative Marker of Resilience or Compensation to Minor Depressive Symptoms in a Nonclinical Sample. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:31354542.' |
case-control studies in major depression have established patterns of regional gray matter loss, including the hippocampus, which might show state-related effects dependent on disease stage. |
2020-09-30 |
2023-08-13 |
human |
| b' Bianca Besteher, Letizia Squarcina, Robert Spalthoff, Marcella Bellani, Christian Gaser, Paolo Brambilla, Igor Nenadi\\xc4\\x8. Hippocampal Volume as a Putative Marker of Resilience or Compensation to Minor Depressive Symptoms in a Nonclinical Sample. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:31354542.' |
we used voxel-based morphometry on a multicenter data set of 409 healthy nonclinical subjects to test the hypothesis that local hippocampal volume would be inversely correlated with subclinical depressive symptoms [symptom checklist 90-revised (scl-90-r) depression scores]. |
2020-09-30 |
2023-08-13 |
human |
| Vigneshvar Chandrasekaran, Vikas Meno. The hippocampus and executive functions in depression: Comments on the article. Industrial psychiatry journal. vol 27. issue 2. 2020-09-30. PMID:31359991. |
the hippocampus and executive functions in depression: comments on the article. |
2020-09-30 |
2023-08-13 |
Not clear |
| Antoine Yrondi, Federico Nemmi, Sophie Billoux, Aurélie Giron, Marie Sporer, Simon Taib, Juliette Salles, Damien Pierre, Claire Thalamas, Laurent Schmitt, Patrice Péran, Christophe Arbu. Significant Decrease in Hippocampus and Amygdala Mean Diffusivity in Treatment-Resistant Depression Patients Who Respond to Electroconvulsive Therapy. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:31607967. |
significant decrease in hippocampus and amygdala mean diffusivity in treatment-resistant depression patients who respond to electroconvulsive therapy. |
2020-09-30 |
2023-08-13 |
Not clear |
| Elian da Silva Francisco, Rosângela Figueiredo Mendes-da-Silva, Cássia Borges Lima de Castro, Geórgia de Sousa Ferreira Soares, Rubem Carlos Araújo Guede. Taurine/Pilocarpine Interaction in the Malnourished Rat Brain: A Behavioral, Electrophysiological, and Immunohistochemical Analysis. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31619952. |
between pnd60 and pnd65, the cortical spreading depression (csd) was recorded in the cerebral cortex, and the levels of malondialdehyde and microglial and astrocyte immunoreactivity were evaluated in the cortex and hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Robert K. S. Wong, Shih-Chieh Chuang, Riccardo Bianch. Metabotropic Glutamate Receptors and Epileptogenesis. Epilepsy currents. vol 2. issue 3. 2020-09-29. PMID:15309152. |
for example, mglur stimulation induces long-term potentiation or depression of excitatory synaptic transmission in the hippocampus. |
2020-09-29 |
2023-08-12 |
Not clear |
| Jiming Han, L U Wang, Hongyan Bian, Xiaoyan Zhou, Cailian Rua. Effects of paroxetine on spatial memory function and protein kinase C expression in a rat model of depression. Experimental and therapeutic medicine. vol 10. issue 4. 2020-09-29. PMID:26622512. |
the application of paroxetine can improve the spatial memory and reverse the changes in pkc levels in the hippocampus in the rat model of depression. |
2020-09-29 |
2023-08-13 |
rat |
| Qiaoer Su, Yifan Cheng, Kunlin Jin, Jianhua Cheng, Yuanshao Lin, Zhenzhen Lin, Liuqing Wang, Bei Sha. Estrogen therapy increases BDNF expression and improves post-stroke depression in ovariectomy-treated rats. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27602095. |
increased brain-derived neurotrophic factor (bdnf) expression was reported in the hippocampus of rats that had been treated with estrogen for two weeks, suggesting that bdnf expression may be an important contributor to the improvement of post-stroke depression that is observed following estrogen therapy. |
2020-09-29 |
2023-08-13 |
rat |
| Sergio D Iñiguez, Antonio Aubry, Lace M Riggs, Jason B Alipio, Roseanna M Zanca, Francisco J Flores-Ramirez, Mirella A Hernandez, Steven J Nieto, David Musheyev, Peter A Serran. Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice. Neurobiology of stress. vol 5. 2020-09-29. PMID:27981196. |
to investigate the neural mechanisms associated with juvenile social stress-induced mood-related endophenotypes, we examined the behavioral, morphological, and biochemical effects of the social defeat stress model of depression on hippocampal dendritic spines within the ca1 stratum radiatum. |
2020-09-29 |
2023-08-13 |
mouse |
| Josh Allen, Raquel Romay-Tallon, Kyle J Brymer, Hector J Caruncho, Lisa E Kalynchu. Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:29928190. |
although depression has historically been linked to alterations in monoaminergic pharmacology and adult hippocampal neurogenesis, new data increasingly implicate broader forms of dampened plasticity, including plasticity within the cell. |
2020-09-29 |
2023-08-13 |
human |
| Shan Tao, Lijie Liu, Lijuan Shi, Xiaowei Li, Pei Shen, Qingying Xun, Xiaojing Guo, Zhiping Yu, Jian Wan. Spatial learning and memory deficits in young adult mice exposed to a brief intense noise at postnatal age. Journal of otology. vol 10. issue 1. 2020-09-29. PMID:29937778. |
the potential role of noise induced hearing loss (nihl), rather than the oxidant stress, has also been indicated by a depression of neurogenesis in the hippocampus long after a brief noise exposure, which produces only a tentative oxidant stress. |
2020-09-29 |
2023-08-13 |
mouse |
| Na Yue, Bing Li, Liu Yang, Qiu-Qin Han, Hui-Jie Huang, Ya-Lin Wang, Jing Wang, Rui Yu, Gen-Cheng Wu, Qiong Liu, Jin Y. Electro-Acupuncture Alleviates Chronic Unpredictable Stress-Induced Depressive- and Anxiety-Like Behavior and Hippocampal Neuroinflammation in Rat Model of Depression. Frontiers in molecular neuroscience. vol 11. 2020-09-29. PMID:29946236. |
electro-acupuncture alleviates chronic unpredictable stress-induced depressive- and anxiety-like behavior and hippocampal neuroinflammation in rat model of depression. |
2020-09-29 |
2023-08-13 |
rat |
| Yea-Hyun Leem, Morimasa Kato, Hyukki Chan. Regular exercise and creatine supplementation prevent chronic mild stress-induced decrease in hippocampal neurogenesis via Wnt/GSK3β/β-catenin pathway. Journal of exercise nutrition & biochemistry. vol 22. issue 2. 2020-09-29. PMID:30149419. |
decreased hippocampal neurogenesis has been observed in patients with depression and in animal models of depression. |
2020-09-29 |
2023-08-13 |
Not clear |
| Lei Gao, Peng Huang, Zhaoyang Dong, Tingting Gao, Shaohui Huang, Chuying Zhou, Yuling Lai, Guanghui Deng, Bin Liu, Ge Wen, Zhiping L. Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent fMRI Signals and Improving Hippocampal Neurogenesis in Mice. Frontiers in pharmacology. vol 9. 2020-09-29. PMID:30323763. |
previous work in our lab has demonstrated that depression induced by chronic stress could generate brain blood oxygen level-dependent (bold) functional magnetic resonance imaging (fmri) signals disorder, accompanied by the impairment of hippocampal neuronal plasticity, decrease of brain-derived neurotrophic factor, and reduction of the number and complexity of adult neurons in the dentate gyrus. |
2020-09-29 |
2023-08-13 |
mouse |
| Lei Gao, Peng Huang, Zhaoyang Dong, Tingting Gao, Shaohui Huang, Chuying Zhou, Yuling Lai, Guanghui Deng, Bin Liu, Ge Wen, Zhiping L. Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent fMRI Signals and Improving Hippocampal Neurogenesis in Mice. Frontiers in pharmacology. vol 9. 2020-09-29. PMID:30323763. |
to test this hypothesis, we examined the effect of modified xiaoyaosan (mxys) on depressive-like behaviors, as well as hippocampal neurogenesis and bold signals in a mice model of chronic unpredictable mild stress (cums)-induced depression. |
2020-09-29 |
2023-08-13 |
mouse |
| Lei Gao, Peng Huang, Zhaoyang Dong, Tingting Gao, Shaohui Huang, Chuying Zhou, Yuling Lai, Guanghui Deng, Bin Liu, Ge Wen, Zhiping L. Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent fMRI Signals and Improving Hippocampal Neurogenesis in Mice. Frontiers in pharmacology. vol 9. 2020-09-29. PMID:30323763. |
mxys exerted anti-depressant effects on cums-induced depression that were similar to the effects of classical antidepressants drug (fluoxetine hydrochloride), with a significant alleviation of depressive-like behaviors, an improvement of hippocampal neurogenesis, and a reversal of activation of bold in the limbic system, particularly in the hippocampus. |
2020-09-29 |
2023-08-13 |
mouse |
| Yu Yang, Weina Ju, Haining Zhang, Li Su. Effect of Ketamine on LTP and NMDAR EPSC in Hippocampus of the Chronic Social Defeat Stress Mice Model of Depression. Frontiers in behavioral neuroscience. vol 12. 2020-09-29. PMID:30356718. |
effect of ketamine on ltp and nmdar epsc in hippocampus of the chronic social defeat stress mice model of depression. |
2020-09-29 |
2023-08-13 |
mouse |
| Haiyan Jiao, Zhiyi Yan, Qingyu Ma, Xiaojuan Li, Youming Jiang, Yueyun Liu, Jiaxu Che. Influence of Xiaoyaosan on depressive-like behaviors in chronic stress-depressed rats through regulating tryptophan metabolism in hippocampus. Neuropsychiatric disease and treatment. vol 15. 2020-09-29. PMID:30587994. |
this study established a depression rat model by the chronic immobilization stress (cis) method and observed the change in tryptophan metabolism in hippocampus and the effects of xiaoyaosan. |
2020-09-29 |
2023-08-13 |
rat |
| Li-Ning Yang, Jun-Cai Pu, Lan-Xiang Liu, Guo-Wei Wang, Xin-Yu Zhou, Yu-Qing Zhang, Yi-Yun Liu, Peng Xi. Integrated Metabolomics and Proteomics Analysis Revealed Second Messenger System Disturbance in Hippocampus of Chronic Social Defeat Stress Rat. Frontiers in neuroscience. vol 13. 2020-09-29. PMID:30983951. |
in this study, we combined a non-targeted gas chromatography-mass spectrometry (gc-ms)-based metabolomic approach and isobaric tags for relative and absolute quantitation (itraq)-based proteomic analysis to elucidate metabolite and protein alterations in the hippocampus of rat after chronic social defeat stress (csds), an extensively used animal model of depression. |
2020-09-29 |
2023-08-13 |
rat |