| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y J Karten, S M Nair, L van Essen, R Sibug, M Joël. Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 23. 1999-12-13. PMID:10557342. |
in the present animal study, we tested one possible mechanism, i.e., that long-term exposure to high corticosterone levels alters functional responses to serotonin in the hippocampus, an important area in the etiology of depression. |
1999-12-13 |
2023-08-12 |
rat |
| G Okugawa, K Omori, J Suzukawa, Y Fujiseki, T Kinoshita, C Inagak. Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones. Journal of neuroendocrinology. vol 11. issue 11. 1999-11-23. PMID:10520140. |
since the glucocorticoid receptor (gr) and/or mineralocorticoid receptor (mr) in the hippocampus have been implicated in cortisol feedback of the hypothalamus-pituitary-adrenal (hpa) axis, abnormalities in those receptors might underlie the hyperactivity of the hpa axis described in patients with major depression. |
1999-11-23 |
2023-08-12 |
rat |
| R Schnabel, I C Kilpatrick, G L Collingridg. An investigation into signal transduction mechanisms involved in DHPG-induced LTD in the CA1 region of the hippocampus. Neuropharmacology. vol 38. issue 10. 1999-11-22. PMID:10530820. |
previously, we have found that activation of mglu receptors using a group i-specific mglu receptor agonist, (rs)-3,5-dhpg, can induce long-term depression (ltd) in the ca1 region of the hippocampus and that, once established, this synaptic depression can be reversed by application of the mglu receptor antagonist, (s)-mcpg [palmer et al., 1997. |
1999-11-22 |
2023-08-12 |
Not clear |
| O Cremona, G Di Paolo, M R Wenk, A Lüthi, W T Kim, K Takei, L Daniell, Y Nemoto, S B Shears, R A Flavell, D A McCormick, P De Camill. Essential role of phosphoinositide metabolism in synaptic vesicle recycling. Cell. vol 99. issue 2. 1999-11-10. PMID:10535736. |
intracellular recording in hippocampal slices revealed enhanced synaptic depression during prolonged high-frequency stimulation followed by delayed recovery. |
1999-11-10 |
2023-08-12 |
mouse |
| M Müller, G G Somje. Intrinsic optical signals in rat hippocampal slices during hypoxia-induced spreading depression-like depolarization. Journal of neurophysiology. vol 82. issue 4. 1999-11-05. PMID:10515971. |
in interfaced rat hippocampal slices spreading depression (sd) and hypoxia-induced sd-like depolarization are associated with increased light reflectance and decreased light transmittance, indicating increased light scattering. |
1999-11-05 |
2023-08-12 |
rat |
| H Takagi, M Takashima, S Y Lio. [Effect of KB-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 111. issue 5. 1999-10-28. PMID:9666486. |
[effect of kb-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices]. |
1999-10-28 |
2023-08-12 |
rat |
| H Takagi, M Takashima, S Y Lio. [Effect of KB-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 111. issue 5. 1999-10-28. PMID:9666486. |
we examined its effects on spreading depression (sd) in rat hippocampal slices as compared with those of flunarizine, dimetotiazine and sumatriptan. |
1999-10-28 |
2023-08-12 |
rat |
| M Ashtari, B S Greenwald, E Kramer-Ginsberg, J Hu, H Wu, M Patel, P Aupperle, S Pollac. Hippocampal/amygdala volumes in geriatric depression. Psychological medicine. vol 29. issue 3. 1999-10-27. PMID:10405084. |
the hippocampus, amygdala and related functional circuits have been implicated in the regulation of emotional expression and memory processes, which are affected in major depression. |
1999-10-27 |
2023-08-12 |
Not clear |
| T Ochiishi, Y Saitoh, A Yukawa, M Saji, Y Ren, T Shirao, H Miyamoto, H Nakata, Y Sekin. High level of adenosine A1 receptor-like immunoreactivity in the CA2/CA3a region of the adult rat hippocampus. Neuroscience. vol 93. issue 3. 1999-10-21. PMID:10473260. |
these results indicate that the adenosine a 1 receptor in ca2/ca3a and the dentate gyrus are in a position to regulate hippocampal theta activity and that resultant strong synaptic depression in ca2/ca3a could play a role in regulating the intrinsic signal flow between ca3 and ca1. |
1999-10-21 |
2023-08-12 |
rat |
| Z C Xu, T M Gao, Y Re. Neurophysiological changes associated with selective neuronal damage in hippocampus following transient forebrain ischemia. Biological signals and receptors. vol 8. issue 4-5. 1999-10-20. PMID:10494015. |
these data suggest that ischemia-induced synaptic potentiation may be associated with the pathogenesis of neuronal damage following ischemia, and that the synaptic depression may have protective effects on hippocampal neurons after ischemic insult. |
1999-10-20 |
2023-08-12 |
rat |
| A M Thomson, A P Banniste. Release-independent depression at pyramidal inputs onto specific cell targets: dual recordings in slices of rat cortex. The Journal of physiology. vol 519 Pt 1. 1999-10-18. PMID:10432339. |
paired intracellular recordings were performed in slices of adult rat neocortex and hippocampus to examine presynaptic depression. |
1999-10-18 |
2023-08-12 |
rat |
| V Klimek, G Rajkowska, S N Luker, G Dilley, H Y Meltzer, J C Overholser, C A Stockmeier, G A Ordwa. Brain noradrenergic receptors in major depression and schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 1. 1999-09-01. PMID:10379521. |
the binding of [125i]p-iodoclonidine to alpha-2, and/or [125i]iodopindolol to beta-1 and beta-2 adrenoceptors was measured in right prefrontal cortex (brodmann's area 10) and right hippocampus from subjects with dsm-iii-r diagnoses of major depression (n = 15) or schizophrenia (n = 8) as well as from control subjects (n = 20). |
1999-09-01 |
2023-08-12 |
human |
| S Latini, F Bordoni, F Pedata, R Corradett. Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices. British journal of pharmacology. vol 127. issue 3. 1999-09-01. PMID:10401564. |
the application of an ischaemic insult in hippocampal slices results in the depression of synaptic transmission, mainly attributed to the activation of a1 adenosine receptors by adenosine released in the extracellular space. |
1999-09-01 |
2023-08-12 |
rat |
| K Jensen, J D Lambert, M S Jense. Activity-dependent depression of GABAergic IPSCs in cultured hippocampal neurons. Journal of neurophysiology. vol 82. issue 1. 1999-08-10. PMID:10400933. |
activity-dependent depression of gabaergic ipscs in cultured hippocampal neurons. |
1999-08-10 |
2023-08-12 |
rat |
| K Jensen, J D Lambert, M S Jense. Activity-dependent depression of GABAergic IPSCs in cultured hippocampal neurons. Journal of neurophysiology. vol 82. issue 1. 1999-08-10. PMID:10400933. |
short-term depression of monosynaptic gabaergic inhibitory postsynaptic currents (ipscs) evoked between pairs of cultured rat hippocampal neurons was investigated using dual whole cell patch-clamp recordings. |
1999-08-10 |
2023-08-12 |
rat |
| K L Smith, J W Swan. Long-term depression of perforant path excitatory postsynaptic potentials following synchronous network bursting in area CA3 of immature hippocampus. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199598. |
various forms of synaptic long-term potentiation and depression have been studied in detail in hippocampus and neocortex. |
1999-07-07 |
2023-08-12 |
Not clear |
| N Kemp, Z I Bashi. Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors. Neuropharmacology. vol 38. issue 4. 1999-07-02. PMID:10221753. |
therefore, these results suggest that pp-lfs can efficiently activate ampa/kainate and mglu receptors in order to induce long-lasting synaptic depression in the ca1 region of the adult hippocampus in vitro. |
1999-07-02 |
2023-08-12 |
Not clear |
| Y I Sheline, M Sanghavi, M A Mintun, M H Gad. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 12. 1999-06-28. PMID:10366636. |
depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. |
1999-06-28 |
2023-08-12 |
human |
| Y I Sheline, M Sanghavi, M A Mintun, M H Gad. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 12. 1999-06-28. PMID:10366636. |
this study takes advantage of continuing advances in the precision of magnetic resonance imaging (mri) to quantify hippocampal volumes in a series of human subjects with a history of depression compared with controls. |
1999-06-28 |
2023-08-12 |
human |
| Y I Sheline, M Sanghavi, M A Mintun, M H Gad. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 12. 1999-06-28. PMID:10366636. |
we sought to test the hypothesis that both age and duration of past depression would be inversely and independently correlated with hippocampal volume. |
1999-06-28 |
2023-08-12 |
human |