Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S H Fatemi, J A Earle, T McMenom. Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. Molecular psychiatry. vol 5. issue 6. 2001-02-15. PMID:11126396. |
reduction in reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. |
2001-02-15 |
2023-08-12 |
human |
S H Fatemi, J A Earle, T McMenom. Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. Molecular psychiatry. vol 5. issue 6. 2001-02-15. PMID:11126396. |
we present new immunocytochemical evidence showing reductions in reelin expression in hippocampus of subjects with schizophrenia, bipolar disorder and major depression and confirm recent reports documenting a similar deficit involving reelin expression in brains of subjects with schizophrenia and bipolar disorder. |
2001-02-15 |
2023-08-12 |
human |
M Monda, A Viggiano, V De Luc. Functional decortication lowers ventromedial hypothalamic activation induced by hippocampal neostigmine injection. Cerebral cortex (New York, N.Y. : 1991). vol 10. issue 12. 2000-12-22. PMID:11073873. |
this experiment tested the effects of cortical spreading depression (csd) on the ventromedial hypothalamic activity and on the related thermogenesis, both stimulated by an injection of neostigmine in the hippocampus. |
2000-12-22 |
2023-08-12 |
rat |
Y Tohdoh, E Narimatsu, M Kawamata, A Namik. The involvement of adenosine neuromodulation in pentobarbital-induced field excitatory postsynaptic potentials depression in rat hippocampal slices. Anesthesia and analgesia. vol 91. issue 6. 2000-12-20. PMID:11094014. |
the involvement of adenosine neuromodulation in pentobarbital-induced field excitatory postsynaptic potentials depression in rat hippocampal slices. |
2000-12-20 |
2023-08-12 |
rat |
Z Xiang, P J Bergol. Synaptic depression and neuronal loss in transiently acidic hippocampal slice cultures. Brain research. vol 881. issue 1. 2000-12-12. PMID:11033097. |
synaptic depression and neuronal loss in transiently acidic hippocampal slice cultures. |
2000-12-12 |
2023-08-12 |
Not clear |
Z Xiang, P J Bergol. Synaptic depression and neuronal loss in transiently acidic hippocampal slice cultures. Brain research. vol 881. issue 1. 2000-12-12. PMID:11033097. |
we used hippocampal slice cultures to examine an immediate effect of acidosis, synaptic depression; and a delayed effect, neuronal loss. |
2000-12-12 |
2023-08-12 |
Not clear |
R M Sapolsk. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063972. |
the possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. |
2000-12-07 |
2023-08-12 |
Not clear |
R M Sapolsk. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063972. |
a number of studies indicate that prolonged, major depression is associated with a selective loss of hippocampal volume that persists long after the depression has resolved. |
2000-12-07 |
2023-08-12 |
Not clear |
R M Sapolsk. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063972. |
the subtypes of depression associated with the hippocampal atrophy typically involve significant hypersecretion of glucocorticoids, and the steroid has a variety of adverse effects in the hippocampus, including causing overt neuron loss. |
2000-12-07 |
2023-08-12 |
Not clear |
G Rajkowsk. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063973. |
it has been proposed that stress-induced changes in the hippocampus may be central to the development of depression in genetically vulnerable individuals. |
2000-12-07 |
2023-08-12 |
Not clear |
G Rajkowsk. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063973. |
new evidence implicates the prefrontal cortex (pfc) in addition to the hippocampus as a site of neuropathology in depression. |
2000-12-07 |
2023-08-12 |
Not clear |
Y I Shelin. 3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063975. |
brain changes associated with early-onset major depression have been reported in the hippocampus, amygdala, caudate nucleus, putamen, and frontal cortex, structures that are extensively interconnected. |
2000-12-07 |
2023-08-12 |
Not clear |
Y I Shelin. 3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063975. |
of these structures, volume loss in the hippocampus is the only consistently observed change to persist past the resolution of the depression. |
2000-12-07 |
2023-08-12 |
Not clear |
M Fujita, D S Charney, R B Inni. Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063976. |
imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations. |
2000-12-07 |
2023-08-12 |
human |
M Fujita, D S Charney, R B Inni. Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063976. |
the hippocampus is likely to be an important brain structure in the pathophysiology of depression because it may mediate both cognitive deficits and hypercortisolemia found in this disorder. |
2000-12-07 |
2023-08-12 |
human |
M Fujita, D S Charney, R B Inni. Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations. Biological psychiatry. vol 48. issue 8. 2000-12-07. PMID:11063976. |
the disparate findings in patients with depression almost certainly reflect the heterogeneity of the disorder, and we highlight the utility of the hippocampus as a useful target region not only to compare depressed subjects with healthy subjects but also to correlate findings with cognitive function and activity of the limbic-hypothalamic-pituitary axis system. |
2000-12-07 |
2023-08-12 |
human |
J E Piletz, H Zhu, G Ordway, C Stockmeier, G Dilly, D Reis, A Halari. Imidazoline receptor proteins are decreased in the hippocampus of individuals with major depression. Biological psychiatry. vol 48. issue 9. 2000-12-07. PMID:11074229. |
imidazoline receptor proteins are decreased in the hippocampus of individuals with major depression. |
2000-12-07 |
2023-08-12 |
human |
A Al-Hayani, S N Davie. Cannabinoid receptor mediated inhibition of excitatory synaptic transmission in the rat hippocampal slice is developmentally regulated. British journal of pharmacology. vol 131. issue 4. 2000-12-05. PMID:11030713. |
the cannabinoid (cb) receptor agonist win55,212-2 (500 nm) had no effect on the first of a pair of population spikes evoked in the ca1 region of hippocampal slices prepared from young adult (4 - 6 weeks old) rats, despite powerfully reducing paired-pulse depression. |
2000-12-05 |
2023-08-12 |
rat |
M R Zamani, N L Desmond, W B Lev. Estradiol modulates long-term synaptic depression in female rat hippocampus. Journal of neurophysiology. vol 84. issue 4. 2000-11-30. PMID:11024072. |
estradiol modulates long-term synaptic depression in female rat hippocampus. |
2000-11-30 |
2023-08-12 |
rat |
L S Leung, J Ma, R S McLachla. Behaviors induced or disrupted by complex partial seizures. Neuroscience and biobehavioral reviews. vol 24. issue 7. 2000-11-16. PMID:10974356. |
in contrast, a convulsive hippocampal or amygdala seizure induced behavioral hypoactivity, perhaps by the spread of the seizure into the frontal cortex and opiate-mediated postictal depression. |
2000-11-16 |
2023-08-12 |
rat |