| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Heldt, L Stanek, J P Chhatwal, K J Ressle. Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories. Molecular psychiatry. vol 12. issue 7. 2007-08-28. PMID:17264839. |
these data suggest that the cognitive deficits and impairment in extinction of aversive memory found in depression and anxiety disorders may be directly related to decreased hippocampal bdnf. |
2007-08-28 |
2023-08-12 |
mouse |
| A Sequeira, T Klempan, L Canetti, J ffrench-Mullen, C Benkelfat, G A Rouleau, G Tureck. Patterns of gene expression in the limbic system of suicides with and without major depression. Molecular psychiatry. vol 12. issue 7. 2007-08-28. PMID:17353912. |
the goal of this study was to identify new molecular targets associated with suicide and with major depression using oligonucleotide microarrays in the limbic system (amygdala, hippocampus, anterior cingulate gryus (ba24) and posterior cingulate gyrus (ba29)). |
2007-08-28 |
2023-08-12 |
human |
| A Sequeira, T Klempan, L Canetti, J ffrench-Mullen, C Benkelfat, G A Rouleau, G Tureck. Patterns of gene expression in the limbic system of suicides with and without major depression. Molecular psychiatry. vol 12. issue 7. 2007-08-28. PMID:17353912. |
limbic expression patterns were most extensively altered in the hippocampus, where processes related to major depression were associated with altered expression of factors involved with transcription and cellular metabolism. |
2007-08-28 |
2023-08-12 |
human |
| A Sequeira, T Klempan, L Canetti, J ffrench-Mullen, C Benkelfat, G A Rouleau, G Tureck. Patterns of gene expression in the limbic system of suicides with and without major depression. Molecular psychiatry. vol 12. issue 7. 2007-08-28. PMID:17353912. |
overall, these data suggest that specific patterns of expression in the limbic system contribute to the etiology of depression and suicidal behaviors and highlight the role of the hippocampus in major depression. |
2007-08-28 |
2023-08-12 |
human |
| Raag D Airan, Leslie A Meltzer, Madhuri Roy, Yuqing Gong, Han Chen, Karl Deisserot. High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science (New York, N.Y.). vol 317. issue 5839. 2007-08-27. PMID:17615305. |
we used quantitative voltage-sensitive dye imaging to probe hippocampal dynamics with millisecond resolution in brain slices after bidirectional modulation of affective state in rat models of depression. |
2007-08-27 |
2023-08-12 |
rat |
| Janne Grønli, Eldbjørg Fiske, Robert Murison, Bjørn Bjorvatn, Eli Sørensen, Reidun Ursin, Chiara M Porta. Extracellular levels of serotonin and GABA in the hippocampus after chronic mild stress in rats. A microdialysis study in an animal model of depression. Behavioural brain research. vol 181. issue 1. 2007-08-24. PMID:17477980. |
hence, the present paper reports a study on simultaneously measurement of hippocampal levels of serotonin and gaba during waking and sleep in the chronic mild stress (cms) animal model of depression. |
2007-08-24 |
2023-08-12 |
rat |
| Mauricio Sandoval, Rodrigo Sandoval, Ulrich Thomas, Christina Spilker, Karl-Heinz Smalla, Romina Falcon, Juan José Marengo, Rodrigo Calderón, Verónica Saavedra, Rolf Heumann, Francisca Bronfman, Craig C Garner, Eckart D Gundelfinger, Ursula Wyneke. Antagonistic effects of TrkB and p75(NTR) on NMDA receptor currents in post-synaptic densities transplanted into Xenopus oocytes. Journal of neurochemistry. vol 101. issue 6. 2007-08-16. PMID:17394529. |
recently, opposing effects of trkb and the pan-neurotrophin receptor p75(ntr) on long-term synaptic depression and long-term potentiation have been reported in the hippocampus. |
2007-08-16 |
2023-08-12 |
rat |
| Keith E Gipson, Mark F Yecke. Coincident glutamatergic and cholinergic inputs transiently depress glutamate release at rat schaffer collateral synapses. Journal of neurophysiology. vol 97. issue 6. 2007-08-15. PMID:17303811. |
in this study, we focused on a transient depression of glutamatergic synaptic transmission at schaffer collateral synapses in acute hippocampal slices. |
2007-08-15 |
2023-08-12 |
rat |
| Ann E Fink, Joshua Sariñana, Erin E Gray, Thomas J O'del. Activity-dependent depression of local excitatory connections in the CA1 region of mouse hippocampus. Journal of neurophysiology. vol 97. issue 6. 2007-08-15. PMID:17409173. |
activity-dependent depression of local excitatory connections in the ca1 region of mouse hippocampus. |
2007-08-15 |
2023-08-12 |
mouse |
| Wui-Man Lau, Guang Qiu, Daiga M Helmeste, Tatia M C Lee, Siu-Wa Tang, Kwok-Fai So, Siu-Wa Tan. Corticosteroid decreases subventricular zone cell proliferation, which could be reversed by paroxetine. Restorative neurology and neuroscience. vol 25. issue 1. 2007-08-15. PMID:17473392. |
increasing evidence supports that antidepressants induce hippocampal neurogenesis and this induces speculation that decrease in hippocampal neurogenesis has causal relationship with depression. |
2007-08-15 |
2023-08-12 |
Not clear |
| Robert E Feldmann, Akira Sawa, Guenter H Seidle. Causality of stem cell based neurogenesis and depression--to be or not to be, is that the question? Journal of psychiatric research. vol 41. issue 9. 2007-08-03. PMID:16889797. |
numerous findings give rise to the hypothesis that depression and declining ng in the hippocampus may be causally connected. |
2007-08-03 |
2023-08-12 |
Not clear |
| Vivien Chevaleyre, Boris D Heifets, Pascal S Kaeser, Thomas C Südhof, Dominick P Purpura, Pablo E Castill. Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alpha. Neuron. vol 54. issue 5. 2007-07-31. PMID:17553427. |
here we show in the hippocampus that long-term, but not short-term, ecb-dependent depression of inhibitory transmission requires presynaptic camp/pka signaling. |
2007-07-31 |
2023-08-12 |
Not clear |
| Vidita A Vaidya, Kimberly Fernandes, Shanker Jh. Regulation of adult hippocampal neurogenesis: relevance to depression. Expert review of neurotherapeutics. vol 7. issue 7. 2007-07-17. PMID:17610392. |
regulation of adult hippocampal neurogenesis: relevance to depression. |
2007-07-17 |
2023-08-12 |
Not clear |
| Vidita A Vaidya, Kimberly Fernandes, Shanker Jh. Regulation of adult hippocampal neurogenesis: relevance to depression. Expert review of neurotherapeutics. vol 7. issue 7. 2007-07-17. PMID:17610392. |
in particular, the addition of new neurons within the hippocampus, a limbic region implicated in mood disorders, is compromised in animal models of depression. |
2007-07-17 |
2023-08-12 |
Not clear |
| Vidita A Vaidya, Kimberly Fernandes, Shanker Jh. Regulation of adult hippocampal neurogenesis: relevance to depression. Expert review of neurotherapeutics. vol 7. issue 7. 2007-07-17. PMID:17610392. |
the 'neurogenic' hypothesis of depression raises the intriguing possibility that hippocampal neurogenesis may contribute to the pathogenesis and treatment of depressive disorders. |
2007-07-17 |
2023-08-12 |
Not clear |
| Vidita A Vaidya, Kimberly Fernandes, Shanker Jh. Regulation of adult hippocampal neurogenesis: relevance to depression. Expert review of neurotherapeutics. vol 7. issue 7. 2007-07-17. PMID:17610392. |
in this review, we discuss the pathways that may mediate the effects of depression models and antidepressants on adult hippocampal neurogenesis, and the promise of these studies in the development of novel antidepressants. |
2007-07-17 |
2023-08-12 |
Not clear |
| Michael Colla, Golo Kronenberg, Michael Deuschle, Kornelia Meichel, Thomas Hagen, Markus Bohrer, Isabella Heuse. Hippocampal volume reduction and HPA-system activity in major depression. Journal of psychiatric research. vol 41. issue 7. 2007-07-16. PMID:17023001. |
hippocampal volume reduction and hpa-system activity in major depression. |
2007-07-16 |
2023-08-12 |
Not clear |
| Michael Colla, Golo Kronenberg, Michael Deuschle, Kornelia Meichel, Thomas Hagen, Markus Bohrer, Isabella Heuse. Hippocampal volume reduction and HPA-system activity in major depression. Journal of psychiatric research. vol 41. issue 7. 2007-07-16. PMID:17023001. |
structural imaging studies investigating hippocampal volumes in patients suffering from major depression have yielded mixed results. |
2007-07-16 |
2023-08-12 |
Not clear |
| I G Sil'ki. [Role of dopamine-dependent negative feedback in the hippocampal--basal ganglia--thalamo---hippocampal loop in response decrement]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 93. issue 3. 2007-07-16. PMID:17598465. |
however, increase in dopamine level and activation of d2 receptors on the striatopallidal cell, while promoting depression of hippocampal inputs, prevents disinhibition of dopaminergic cells, and their reactions start their decrement. |
2007-07-16 |
2023-08-12 |
Not clear |
| Y Bogoch, Y N Biala, M Linial, M Weinstoc. Anxiety induced by prenatal stress is associated with suppression of hippocampal genes involved in synaptic function. Journal of neurochemistry. vol 101. issue 4. 2007-07-12. PMID:17254015. |
exposure of pregnant women or animals to stress during a critical period of foetal brain development increases the likelihood of anxiety, depression and learning deficits that are associated with structural alterations in the offspring hippocampus. |
2007-07-12 |
2023-08-12 |
rat |