All Relations between Depression and hippocampus

Publication Sentence Publish Date Extraction Date Species
Hu-Jiang Shi, Yi-Ren Xue, Hua Shao, Cheng Wei, Ting Liu, Jie He, Yu-Hao Yang, Hong-Mei Wang, Na Li, Si-Qiang Ren, Lei Chang, Zhen Wang, Li-Juan Zh. Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours. Brain : a journal of neurology. 2024-05-03. PMID:38701344. we now elucidate hippocampal excitation-inhibition (e/i) balance underlies the regulatory effects of 5-ht2cr in depression. 2024-05-03 2024-05-06 Not clear
Sarah Nicolas, Sebastian Dohm-Hansen, Aonghus Lavelle, Thomaz F S Bastiaanssen, Jane A English, John F Cryan, Yvonne M Nola. Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats. Translational psychiatry. vol 14. issue 1. 2024-04-24. PMID:38658547. lifestyle factors, especially exercise, impact the manifestation and progression of psychiatric and neurodegenerative disorders such as depression and alzheimer's disease, mediated by changes in hippocampal neuroplasticity. 2024-04-24 2024-04-28 rat
You Yang, Dongyu Zhou, Su Min, Di Liu, Mou Zou, Chang Yu, Lihao Chen, Jia Huang, Ruiyang Hon. Ciprofol ameliorates ECS-induced learning and memory impairment by modulating aerobic glycolysis in the hippocampus of depressive-like rats. Pharmacology, biochemistry, and behavior. 2024-04-24. PMID:38657873. electroconvulsive shock (ecs) is utilized to treat depression but may cause learning/memory impairments, which may be ameliorated by anesthetics through the modulation of hippocampal synaptic plasticity. 2024-04-24 2024-04-28 rat
Bandar N Aljafen, Ruwa Alneseyan, Taim Muayqil, Mashael O Alkhateeb, Mubarak M Aldosari, Aya Alsermani, Lujain Alnakhli, Renad Althomali, Razan Alnami, Ruba Alqahtani, Lama Ibrahim, Fawzi Babtai. Evaluating the prevalence and risk factors for depression in patients with temporal lobe epilepsy with hippocampal sclerosis: A cross-sectional multicenter study. Epilepsy & behavior : E&B. vol 154. 2024-04-18. PMID:38636108. evaluating the prevalence and risk factors for depression in patients with temporal lobe epilepsy with hippocampal sclerosis: a cross-sectional multicenter study. 2024-04-18 2024-04-21 Not clear
Lisa Blum Moyse, Hugues Berr. A coupled neural field model for the standard consolidation theory. Journal of theoretical biology. 2024-04-15. PMID:38621583. this suggests that neurogenesis in the hippocampus and distance-dependent synaptic plasticity coupled to synaptic depression and spike frequency adaptation, are indeed critical neurobiological processes in memory consolidation. 2024-04-15 2024-04-18 Not clear
Amine Bah. Serotonin transporter knockdown relieves depression-like behavior and ethanol-induced CPP in mice after chronic social defeat stress. Behavioural brain research. 2024-04-13. PMID:38614210. to further investigate this hypothesis, we used a lentiviral-mediated knockdown approach to examine the role of hippocampal sert knockdown in social defeat stress-elicited depression like behavior and ethanol-induced place preference (cpp). 2024-04-13 2024-04-16 mouse
Qi Xu, Lihong Sun, Qing Chen, Cuicui Jiao, Yuan Wang, Hua Li, Jiaqian Xie, Fangfang Zhu, Jiangling Wang, Wen Zhang, Linghua Xie, Hui Wu, Zhiyi Zuo, Xinzhong Che. Gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal NLRP3-mediated neuroinflammation in a postpartum depression mouse model. Brain, behavior, and immunity. 2024-04-10. PMID:38599497. gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal nlrp3-mediated neuroinflammation in a postpartum depression mouse model. 2024-04-10 2024-04-13 mouse
Jiuseng Zeng, Li Chen, Xi Peng, Fei Luan, Jingwen Hu, Zhiqiang Xie, Hongxiao Xie, Rong Liu, Haizhen Lv, Nan Zen. The anti-depression effect and potential mechanism of the petroleum ether fraction of CDB: Integrated network pharmacology and metabolomics. Heliyon. vol 10. issue 7. 2024-04-08. PMID:38586416. afterward, a cums mouse depression model was established and lc-ms-based untargeted hippocampal metabolomics was performed to identify differential metabolites, and related metabolic pathways. 2024-04-08 2024-04-10 mouse
Zarah R Haniff, Mariia Bocharova, Tim Mantingh, James J Rucker, Latha Velayudhan, David M Taylor, Allan H Young, Dag Aarsland, Anthony C Vernon, Sandrine Thure. Psilocybin for dementia prevention? The potential role of psilocybin to alter mechanisms associated with major depression and neurodegenerative diseases. Pharmacology & therapeutics. 2024-04-07. PMID:38583670. in this narrative review, we focus on the evidence base for the effects of psilocybin on adult hippocampal neurogenesis and microglial form and function; which may suggest that psilocybin has the potential to modulate multiple mechanisms of action, and may have implications in altering the progression from major depression to dementia in those at risk. 2024-04-07 2024-04-10 Not clear
Jun Chang, Huimin Yang, Xiaoqian Shan, Lan Zhao, Yujiao Li, Zhao Zhang, Joseph Kofi Abankwah, Mingxing Zhang, Yuhong Bian, Yi Gu. Bergamot essential oil improves CUMS-induced depression-like behaviour in rats by protecting the plasticity of hippocampal neurons. Journal of cellular and molecular medicine. vol 28. issue 8. 2024-03-30. PMID:38553964. collectively, inhaled beo mitigates depression by protecting the plasticity of hippocampal neurons, hence, providing novel insights into treatment of depression. 2024-03-30 2024-04-01 rat
Yangdong Zhang, Haiyang Wang, Lanxiang Liu, Xiaolong Mo, Dian He, Xueyi Chen, Rui Xiao, Qisheng Cheng, Madiha Fatima, Yamei Du, Peng Xi. Maternal Separation Regulates Sensitivity of Stress-Induced Depression in Mice by Affecting Hippocampal Metabolism. Physiology & behavior. 2024-03-29. PMID:38552706. maternal separation regulates sensitivity of stress-induced depression in mice by affecting hippocampal metabolism. 2024-03-29 2024-04-01 mouse
Xiang-Ming Cai, Xiao-Yu Sun, Rui Li, Pei-Juan Wang, Jian-Cheng Qi, Yu-Xin Ge, Lei Yan. The hippocampal Salt-Inducible Kinase 2-CREB-Regulated Transcription Co-activator 1 system mediates the antidepressant actions of paroxetine in mice. Behavioural brain research. 2024-03-29. PMID:38552744. the hippocampal salt-inducible kinase 2 (sik2)-creb-regulated transcription co-activator 1 (crtc1) system has been demonstrated to participate in not only the pathogenesis of depression but also the antidepressant mechanisms of several antidepressant medications including fluoxetine, paroxetine, and mirtazapine. 2024-03-29 2024-04-01 mouse
Xiang-Ming Cai, Xiao-Yu Sun, Rui Li, Pei-Juan Wang, Jian-Cheng Qi, Yu-Xin Ge, Lei Yan. The hippocampal Salt-Inducible Kinase 2-CREB-Regulated Transcription Co-activator 1 system mediates the antidepressant actions of paroxetine in mice. Behavioural brain research. 2024-03-29. PMID:38552744. our results show that the antidepressant actions of paroxetine in mice models of depression were accompanied by its preventing effects against chronic stress on hippocampal sik2, crtc1, and crtc1-creb binding. 2024-03-29 2024-04-01 mouse
Laipeng Feng, Huiying Wang, Chen Chen, Jiacheng Fu, Liqin Zhao, Xia Zhao, Mengjun Geng, Mengdi Ren, Lidan Tong, Yan Li, Jingyang Gu, Chonghong Wan. MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats. Behavioural brain research. 2024-03-18. PMID:38499157. mkp1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats. 2024-03-18 2024-03-21 rat
Laipeng Feng, Huiying Wang, Chen Chen, Jiacheng Fu, Liqin Zhao, Xia Zhao, Mengjun Geng, Mengdi Ren, Lidan Tong, Yan Li, Jingyang Gu, Chonghong Wan. MKP1 may be involved in the occurrence of depression by regulating hippocampal autophagy in rats. Behavioural brain research. 2024-03-18. PMID:38499157. we speculated that mkp1 contributes to depression by enhancing hippocampal autophagy through dephosphorylation of the mapk isoform erk1/2. 2024-03-18 2024-03-21 rat
Yue Li, Yanmin Luo, Peilin Zhu, Xin Liang, Jing Li, Xiaoyun Dou, Li Liu, Lu Qin, Mei Zhou, Yuhui Deng, Lin Jiang, Shun Wang, Wenyu Yang, Jing Tang, Yong Tan. Running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of CUS-induced depression model mice. Pharmacology, biochemistry, and behavior. 2024-03-17. PMID:38494007. running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of cus-induced depression model mice. 2024-03-17 2024-03-20 mouse
Ying Ma, Yue Qiao, Xiang Ga. Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488549. potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. 2024-03-15 2024-03-17 Not clear
Ying Ma, Yue Qiao, Xiang Ga. Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488549. one of possible factors underlying the depression is the reduction of adult hippocampal neurogenesis which may come from less physical activity, social isolation, chronic pain, and elevated neuroinflammation after spinal cord injury. 2024-03-15 2024-03-17 Not clear
Ying Ma, Yue Qiao, Xiang Ga. Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488549. finally, we will outline the potential therapeutic options aimed at enhancing hippocampal neurogenesis to ameliorate depression. 2024-03-15 2024-03-17 Not clear
Yingying Chen, Xiaodi Xia, Zheyi Zhou, Meng Yuan, Yadong Peng, Ying Liu, Jinxiang Tang, Yixiao F. Interleukin-6 is correlated with amygdala volume and depression severity in adolescents and young adults with first-episode major depressive disorder. Brain imaging and behavior. 2024-03-12. PMID:38467915. in this study, we aimed to investigate the potential correlations among cytokines, depression severity, and the volumes of the amygdala, hippocampus, and nucleus accumbens in han chinese adolescents and young adults with first-episode mdd. 2024-03-12 2024-03-14 Not clear