| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Huang, Hua Fan, Yan-Mei Chen, Cheng-Niu Wang, Wei Guan, Wei-Yu Li, Tian-Shun Shi, Wei-Jia Chen, Bao-Lun Zhu, Jian-Feng Liu, Bo Jian. The salt-inducible kinases inhibitor HG-9-91-01 exhibits antidepressant-like actions in mice exposed to chronic unpredictable mild stress. Neuropharmacology. 2023-01-26. PMID:36702294. |
we have previously demonstrated that hippocampal salt-inducible kinase 2 (sik2) plays a role in the pathogenesis of depression via regulating the downstream creb-regulated transcription coactivator 1 (crtc1)-camp response element-binding protein (creb)-brain derived neurotrophic factor (bdnf) pathway. |
2023-01-26 |
2023-08-14 |
mouse |
| Else Schneider, Jessica P K Doll, Nina Schweinfurth, Cedric Kettelhack, Anna-Chiara Schaub, Gulnara Yamanbaeva, Nimmy Varghese, Laura Mählmann, Serge Brand, Anne Eckert, Stefan Borgwardt, Undine E Lang, André Schmid. Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial. Journal of psychiatry & neuroscience : JPN. vol 48. issue 1. 2023-01-18. PMID:36653035. |
effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and bdnf in patients with depression: a secondary analysis of a randomized controlled trial. |
2023-01-18 |
2023-08-14 |
Not clear |
| Ziteng Xie, Xiaomeng Xu, Wenbo Cao, Luyun He, Chen Kou, Jiajia He, Yaping Guo, Mingjin Yue, Saijun M. Perspectives on miRNAs directly targeting BDNF for cancer diagnosis and treatment (Review). International journal of oncology. vol 62. issue 2. 2023-01-12. PMID:36633145. |
abnormal expression of bdnf is also closely related to the development of cancer, cancer‑related pain and depression. |
2023-01-12 |
2023-08-14 |
Not clear |
| Smaragda Ntona, Apostolis Papaefthymiou, Jannis Kountouras, Dimitra Gialamprinou, Georgios Kotronis, Marina Boziki, Stergios A Polyzos, Maria Tzitiridou, Dimitrios Chatzopoulos, Tharshika Thavayogarajah, Ioanna Gkolia, Georgios Ntonas, Elisabeth Vardaka, Michael Doulberi. Impact of nonalcoholic fatty liver disease-related metabolic state on depression. Neurochemistry international. 2023-01-12. PMID:36634820. |
furthermore, reduced levels of nesfatin-1 and copine-6-associated bdnf (brain-derived neurotrophic factor) levels have been considered as a probable link between nafld and depression. |
2023-01-12 |
2023-08-14 |
Not clear |
| Jeffrey J Moffat, Samuel A Sakhai, Zachary W Hoisington, Yann Ehinger, Dorit Ro. The BDNF Val68Met polymorphism causes a sex specific alcohol preference over social interaction and also acute tolerance to the anxiolytic effects of alcohol, a phenotype driven by malfunction of BDNF in the ventral hippocampus of male mice. Psychopharmacology. 2023-01-09. PMID:36622381. |
the brain-derived neurotrophic factor (bdnf) valine 66 to methionine human polymorphism results in impaired activity-dependent bdnf release and has been linked to psychiatric disorders including depression and anxiety. |
2023-01-09 |
2023-08-14 |
mouse |
| Yiyi Li, Hongyu Chen, Jianhao Wang, Jiabei Wang, Xuan Niu, Chao Wang, Dongdong Qin, Fang Li, Yamei Wang, Jing Xiong, Songyan Liu, Liqin Huang, Xi Zhang, Feng Gao, Dandan Gao, Mingxia Fan, Xuan Xiao, Zhi-Hao Wan. Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice. Frontiers in molecular neuroscience. vol 15. 2022-12-29. PMID:36578534. |
therefore, our findings aim to demonstrate that the inflammation-activated neuronal c/ebpβ promotes hfd-induced depression by diminishing bdnf expression. |
2022-12-29 |
2023-08-14 |
mouse |
| Emily J Jaehne, Jessica N Kent, Nikki Lam, Lina Schonfeld, Jereme G Spiers, Veronica Begni, Federico De Rosa, Marco A Riva, Maarten van den Buus. Chronic running-wheel exercise from adolescence leads to increased anxiety and depression-like phenotypes in adulthood in rats: Effects on stress markers and interaction with BDNF Val66Met genotype. Developmental psychobiology. vol 65. issue 1. 2022-12-26. PMID:36567651. |
the bdnf val66met polymorphism is associated with reduced activity-dependent bdnf release and increased risk for anxiety and depression. |
2022-12-26 |
2023-08-14 |
rat |
| Saumya Singh, Katarine Fereshetyan, Susan Shorter, Ruslan Paliokha, Eliyahu Dremencov, Konstantin Yenkoyan, Saak V Ovsepia. Brain-derived neurotrophic factor (BDNF) in perinatal depression: side show or pivotal factor? Drug discovery today. 2022-12-17. PMID:36528281. |
brain-derived neurotrophic factor (bdnf) in perinatal depression: side show or pivotal factor? |
2022-12-17 |
2023-08-14 |
Not clear |
| Saumya Singh, Katarine Fereshetyan, Susan Shorter, Ruslan Paliokha, Eliyahu Dremencov, Konstantin Yenkoyan, Saak V Ovsepia. Brain-derived neurotrophic factor (BDNF) in perinatal depression: side show or pivotal factor? Drug discovery today. 2022-12-17. PMID:36528281. |
in this review, we highlight the emerging role of bdnf in reproductive biology and discuss evidence suggesting its deficiency as a risk factor for perinatal depression. |
2022-12-17 |
2023-08-14 |
Not clear |
| Saumya Singh, Katarine Fereshetyan, Susan Shorter, Ruslan Paliokha, Eliyahu Dremencov, Konstantin Yenkoyan, Saak V Ovsepia. Brain-derived neurotrophic factor (BDNF) in perinatal depression: side show or pivotal factor? Drug discovery today. 2022-12-17. PMID:36528281. |
with the increasing evidence for restoration of serum bdnf levels by antidepressant therapy, the strengthening association of perinatal depression with deficiency of bdnf advocates its potential as a surrogate endpoint for preclinical and clinical studies. |
2022-12-17 |
2023-08-14 |
Not clear |
| María Luisa Delgado-Losada, Jaime Bouhaben, Eduardo Arroyo-Pardo, Aránzazu Aparicio, Ana María López-Parr. Loneliness, Depression, and Genetics in the Elderly: Prognostic Factors of a Worse Health Condition? International journal of environmental research and public health. vol 19. issue 23. 2022-12-11. PMID:36497531. |
therefore, it follows that telomeres and bdnf play a role as intermediaries between loneliness and depression and their relationship with a worse state of health. |
2022-12-11 |
2023-08-14 |
Not clear |
| Agata Gabryelska, Szymon Turkiewicz, Marta Ditmer, Filip Franciszek Karuga, Dominik Strzelecki, Piotr Białasiewicz, Marcin Socha. BDNF and proBDNF Serum Protein Levels in Obstructive Sleep Apnea Patients and Their Involvement in Insomnia and Depression Symptoms. Journal of clinical medicine. vol 11. issue 23. 2022-12-11. PMID:36498709. |
bdnf and probdnf serum protein levels in obstructive sleep apnea patients and their involvement in insomnia and depression symptoms. |
2022-12-11 |
2023-08-14 |
Not clear |
| Agata Gabryelska, Szymon Turkiewicz, Marta Ditmer, Filip Franciszek Karuga, Dominik Strzelecki, Piotr Białasiewicz, Marcin Socha. BDNF and proBDNF Serum Protein Levels in Obstructive Sleep Apnea Patients and Their Involvement in Insomnia and Depression Symptoms. Journal of clinical medicine. vol 11. issue 23. 2022-12-11. PMID:36498709. |
brain-derived neurotrophic factor (bdnf) signaling pathway is involved in the pathophysiology of depression and insomnia. |
2022-12-11 |
2023-08-14 |
Not clear |
| Humna Liaqat, Amna Parveen, Sun-Yeou Ki. Antidepressive Effect of Natural Products and Their Derivatives Targeting BDNF-TrkB in Gut-Brain Axis. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499295. |
signaling via bdnf and its receptor tropomyosin receptor kinase b (trkb) plays a vital role in the etiopathogenesis of depression and the therapeutic mechanism of antidepressants. |
2022-12-11 |
2023-08-14 |
Not clear |
| Maria Pina Serra, Francesco Sanna, Marianna Boi, Laura Poddighe, Lorenzo Secci, Marcello Trucas, Alberto Fernández-Teruel, Maria Giuseppa Corda, Osvaldo Giorgi, Marina Quart. Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499323. |
the present work was undertaken to investigate the effects of acute forced swimming (fs) on the levels of brain-derived neurotrophic factor (bdnf) and tyrosine kinase receptor b (trkb) proteins in: the ventral tegmental area (vta); the nucleus accumbens (acb) shell and core compartments; and the anterior cingulate (acg), prelimbic (pl) and infralimbic (il) territories of the prefrontal cortex of genetic models of vulnerability (rla, roman low-avoidance rats) and resistance (rha, roman high-avoidance rats) to stress-induced depression. |
2022-12-11 |
2023-08-14 |
rat |
| Rafaella A Gonçalves, Felipe K Sudo, Mychael V Lourenco, Claudia Drummond, Naima Assunção, Bart Vanderborght, Danielle D P Ferreira, Felipe C Ribeiro, Fabricio A Pamplona, Fernanda Tovar-Moll, Paulo Mattos, Sergio T Ferreira, Fernanda G De Felic. Cerebrospinal fluid irisin and lipoxin A4 are reduced in elderly Brazilian individuals with depression: Insight into shared mechanisms between depression and dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-12-05. PMID:36465055. |
reduced brain-derived neurotrophic factor (bdnf) and neuroinflammation are implicated in the pathophysiology of depression and dementia. |
2022-12-05 |
2023-08-14 |
human |
| Anita E Autr. Function of brain-derived neurotrophic factor in the hypothalamus: Implications for depression pathology. Frontiers in molecular neuroscience. vol 15. 2022-12-05. PMID:36466807. |
both clinical and preclinical research have implicated a critical role for brain-derived neurotrophic factor (bdnf) signaling in depression pathology as well as therapeutics. |
2022-12-05 |
2023-08-14 |
Not clear |
| Anita E Autr. Function of brain-derived neurotrophic factor in the hypothalamus: Implications for depression pathology. Frontiers in molecular neuroscience. vol 15. 2022-12-05. PMID:36466807. |
here, we review evidence for the role of bdnf and trkb signaling in the regions of the hypothalamus and their role in these autonomic and behavioral functions associated with depression. |
2022-12-05 |
2023-08-14 |
Not clear |
| Anita E Autr. Function of brain-derived neurotrophic factor in the hypothalamus: Implications for depression pathology. Frontiers in molecular neuroscience. vol 15. 2022-12-05. PMID:36466807. |
understanding the role of bdnf signaling in the hypothalamus will lead to valuable insights for sex- and stress-dependent neurobiological underpinnings of depression pathology. |
2022-12-05 |
2023-08-14 |
Not clear |
| Shuyue Cheng, Wei Wang, Zemeng Zhu, Mingyue Zhao, Hannao Li, Dexiang Liu, Fang Pa. Involvement of brain-derived neurotrophic factor methylation in the prefrontal cortex and hippocampus induced by chronic unpredictable mild stress in male mice. Journal of neurochemistry. 2022-12-01. PMID:36453259. |
early life stress alters brain-derived neurotrophic factor (bdnf) promoter iv methylation and bdnf expression, which is closely related to the pathophysiological process of depression. |
2022-12-01 |
2023-08-14 |
mouse |