| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patrizia Amadio, Chiara Macchi, Chiara Favero, Marta Zarà, Giulia Solazzo, Laura Dioni, Leonardo Sandrini, Luisella Vigna, Maria Francesca Greco, Massimiliano Buoli, Cesare R Sirtori, Angela Cecilia Pesatori, Alessandro Ieraci, Massimiliano Ruscica, Silvia Stella Barbieri, Valentina Bollat. Brain-Derived Neurotrophic Factor and Extracellular Vesicle-Derived miRNAs in an Italian Cohort of Individuals With Obesity: A Key to Explain the Link Between Depression and Atherothrombosis. Frontiers in cardiovascular medicine. vol 9. 2022-08-01. PMID:35911513. |
since the relationship among peripheral bdnf, depression and obesity is not well-defined, the aim of the present report has been to address this issue taking advantage of the contribution played by extracellular vesicle (ev)-derived mirnas. |
2022-08-01 |
2023-08-14 |
human |
| Catalina Torres Soler, Sofia H Kanders, Susanne Olofsdotter, Sofia Vadlin, Cecilia Åslund, Kent W Nilsso. Exploration of the Moderating Effects of Physical Activity and Early Life Stress on the Relation between Brain-Derived Neurotrophic Factor (BDNF) rs6265 Variants and Depressive Symptoms among Adolescents. Genes. vol 13. issue 7. 2022-07-28. PMID:35886019. |
allele a of the brain-derived neurotrophic factor (bdnf) rs6265 is considered to be a risk factor for depression. |
2022-07-28 |
2023-08-16 |
Not clear |
| Boyoung Lee, Eunjin Shin, Inwoong Song, Bomi Chan. Depression in Adolescence and Brain-Derived Neurotrophic Factor. Frontiers in molecular neuroscience. vol 15. 2022-07-25. PMID:35875661. |
brain-derived neurotrophic factor (bdnf) is known to play a critical role in the pathophysiology of many psychiatric disorders, including depression. |
2022-07-25 |
2023-08-14 |
Not clear |
| Boyoung Lee, Eunjin Shin, Inwoong Song, Bomi Chan. Depression in Adolescence and Brain-Derived Neurotrophic Factor. Frontiers in molecular neuroscience. vol 15. 2022-07-25. PMID:35875661. |
therefore, in this review paper, the causes and treatment of adolescent depression and the function of bdnf are investigated. |
2022-07-25 |
2023-08-14 |
Not clear |
| Weronika Jasmina Forys, Tracey Tokuhama-Espinos. The Athlete's Paradox: Adaptable Depression. Sports (Basel, Switzerland). vol 10. issue 7. 2022-07-25. PMID:35878116. |
the research revealed that 5-httlpr polymorphism, brain-derived neurotrophic factor (bdnf), extensive psychological demands, social stigma, and overtraining syndrome (ots) may all contribute to a unique version of depression. |
2022-07-25 |
2023-08-14 |
Not clear |
| Christian Berthou, Jean Paul Iliou, Denis Barb. Iron, neuro-bioavailability and depression. EJHaem. vol 3. issue 1. 2022-07-18. PMID:35846210. |
noradrenaline also has impact on neuroplasticity via brain-derived neurotrophic factor (bdnf), which is key for prefrontal and hippocampus neurons playing a role in depression. |
2022-07-18 |
2023-08-14 |
Not clear |
| Lin-Sheng Shi, Chun-Hui Ji, Wen-Qian Tang, Yue Liu, Wei Zhang, Wei Gua. Hippocampal miR-124 participates in the pathogenesis of depression via regulating the expression of BDNF in a Chronic Social Defeat Stress model of depression. Current neurovascular research. 2022-07-15. PMID:35838216. |
hippocampal mir-124 participates in the pathogenesis of depression via regulating the expression of bdnf in a chronic social defeat stress model of depression. |
2022-07-15 |
2023-08-14 |
mouse |
| Lin-Sheng Shi, Chun-Hui Ji, Wen-Qian Tang, Yue Liu, Wei Zhang, Wei Gua. Hippocampal miR-124 participates in the pathogenesis of depression via regulating the expression of BDNF in a Chronic Social Defeat Stress model of depression. Current neurovascular research. 2022-07-15. PMID:35838216. |
conclusion hippocampal mir-124 participated in the pathogenesis of depression by regulating bdnf biosynthesis and was a feasible antidepressant target. |
2022-07-15 |
2023-08-14 |
mouse |
| Bing-Xin Sun, Ai-Shi Peng, Pei-Jie Liu, Min-Jia Wang, Hai-Li Ding, Yu-Shi Hu, Liang Kan. Neuroprotection of exercise: P2X4R and P2X7R regulate BDNF actions. Purinergic signalling. 2022-07-13. PMID:35821455. |
the neurotrophin brain-derived neurotrophic factor (bdnf), which acts as a transducer, is responsible for improving cerebral stroke, neuropathic pain, and depression. |
2022-07-13 |
2023-08-14 |
mouse |
| Riley A Williams, Kenneth W Johnson, Francis S Lee, Hugh C Hemmings, Jimcy Plathol. A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures. Frontiers in molecular neuroscience. vol 15. 2022-07-11. PMID:35813074. |
here, we show that brain-derived neurotrophic factor (bdnf), a growth factor implicated in synaptic plasticity and dysfunction, enhances glutamate synaptic vesicle exocytosis, and that attenuation of vesicular bdnf release by isoflurane contributes to transient depression of excitatory synaptic transmission in mice. |
2022-07-11 |
2023-08-14 |
mouse |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
relationship and effect of mir-1-3p expression and bdnf level in patients with primary hypertension complicated with depression. |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
this experiment was designed to explore the relationship and effect of mir-1-3p expression and bdnf level in patients with primary hypertension complicated with depression. |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
results showed that compared with the normal control group, while mir-1-3p expression increased obviously in patients with hypertension, while the level of bdnf decreased significantly; and compared with patients with simple hypertension, the expression of mir-1-3p in hypertension patients with depression was significantly increased, while bdnf level was decreased evidently (all p < 0.05). |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
mir-1-3p expression in patients with hypertension complicated with depression was negatively correlated with serum bdnf level (r=-0.302, p < 0.05). |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
in relative to the normal control population, the area under the curve (auc) of roc produced by serum mir-1-3p and bdnf in patients with primary hypertension complicated with depression was 0.971 (95% ci = 0.945-0.998, p < 0.0001) and 0.875 (95% ci = 0.808-0.942, p < 0.0001); and in relative to primary hypertension patients without depression, the auc of roc produced by serum mir-1-3p and bdnf in patients with primary hypertension with depression was 0.957 (95% ci = 0.925-0.989, p < 0.0001) and 0.883 (95% ci = 0.821-0.944, p < 0.0001), respectively. |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
hads-d score, hamd score, course of the disease, mir-1-3p expression and bdnf level showed statistical differences in primary hypertension patients with and without depression (all p < 0.05). |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
it was concluded that there are high mir-1-3p expression and low serum bdnf levels in patients with primary hypertension complicated with depression. |
2022-07-09 |
2023-08-14 |
human |
| Jihong Ding, Chunyu Jiang, Le Yang, Xianyan Wan. Relationship and effect of miR-1-3p expression and BDNF level in patients with primary hypertension complicated with depression. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809326. |
detecting mir-1-3p and bdnf in patients with primary hypertension can indicate the occurrence of depression to some extent. |
2022-07-09 |
2023-08-14 |
human |
| Amanda Vega-Núñez, Carlos Gómez-Sánchez-Lafuente, Fermín Mayoral-Cleries, Antonio Bordallo, Fernando Rodríguez de Fonseca, Juan Suárez, José Guzmán-Parr. Clinical Value of Inflammatory and Neurotrophic Biomarkers in Bipolar Disorder: A Systematic Review and Meta-Analysis. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740389. |
the main finding of the meta-analysis was a negative correlation between circulating levels of bdnf and depression severity score (standardized mean difference = -0.22, confidence interval 95% = -0.38, -0.05, |
2022-06-24 |
2023-08-14 |
Not clear |
| Jing Ren, Chenyang Li, Songren Wei, Yanjun He, Peng Huang, Jiangping X. Identifying Antidepressant Effects of Brain-Derived Neurotrophic Factor and IDO1 in the Mouse Model Based on RNA-Seq Data. Frontiers in genetics. vol 13. 2022-06-17. PMID:35711916. |
deletion of brain-derived neurotrophic factor (bdnf) and upregulation of indoleamine 2,3-dioxygenase 1 (ido1) are associated with depression severity in animals. |
2022-06-17 |
2023-08-14 |
mouse |