| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| André R Brunoni, Rodrigo Machado-Vieira, Carlos A Zarate, Erica L M Vieira, Marie-Anne Vanderhasselt, Michael A Nitsche, Leandro Valiengo, Isabela M Benseñor, Paulo A Lotufo, Wagner F Gattaz, Antonio L Teixeir. BDNF plasma levels after antidepressant treatment with sertraline and transcranial direct current stimulation: results from a factorial, randomized, sham-controlled trial. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 7. 2015-02-12. PMID:24702987. |
in addition, no significant changes were observed in responders and non-responders as well as no relationships between bdnf levels and clinical and psychopathological variables related to depression. |
2015-02-12 |
2023-08-13 |
human |
| André R Brunoni, Rodrigo Machado-Vieira, Carlos A Zarate, Erica L M Vieira, Marie-Anne Vanderhasselt, Michael A Nitsche, Leandro Valiengo, Isabela M Benseñor, Paulo A Lotufo, Wagner F Gattaz, Antonio L Teixeir. BDNF plasma levels after antidepressant treatment with sertraline and transcranial direct current stimulation: results from a factorial, randomized, sham-controlled trial. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 7. 2015-02-12. PMID:24702987. |
regarding tdcs, bdnf plasma levels might not be a good candidate biomarker to evaluate depression improvement or be a predictor of response in patients treated with tdcs, as our results showed that bdnf increase was not necessary to induce clinical response. |
2015-02-12 |
2023-08-13 |
human |
| André R Brunoni, Rodrigo Machado-Vieira, Carlos A Zarate, Erica L M Vieira, Marie-Anne Vanderhasselt, Michael A Nitsche, Leandro Valiengo, Isabela M Benseñor, Paulo A Lotufo, Wagner F Gattaz, Antonio L Teixeir. BDNF plasma levels after antidepressant treatment with sertraline and transcranial direct current stimulation: results from a factorial, randomized, sham-controlled trial. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 7. 2015-02-12. PMID:24702987. |
finally, our findings do not support a relationship between bdnf and improvement of depression. |
2015-02-12 |
2023-08-13 |
human |
| Roman Gersner, Ram Gal, Ofir Levit, Hagar Moshe, Abraham Zange. Inherited behaviors, BDNF expression and response to treatment in a novel multifactorial rat model for depression. The international journal of neuropsychopharmacology. vol 17. issue 6. 2015-01-22. PMID:24513109. |
inherited behaviors, bdnf expression and response to treatment in a novel multifactorial rat model for depression. |
2015-01-22 |
2023-08-12 |
rat |
| Roman Gersner, Ram Gal, Ofir Levit, Hagar Moshe, Abraham Zange. Inherited behaviors, BDNF expression and response to treatment in a novel multifactorial rat model for depression. The international journal of neuropsychopharmacology. vol 17. issue 6. 2015-01-22. PMID:24513109. |
in addition, lower bdnf levels are observed in the dorsal hippocampus of drl rats, complying with the neurotrophic hypothesis of depression. |
2015-01-22 |
2023-08-12 |
rat |
| Yixuan Song, Koichi Miyaki, Tomoko Suzuki, Yasuharu Sasaki, Akizumi Tsutsumi, Norito Kawakami, Akihito Shimazu, Masaya Takahashi, Akiomi Inoue, Chiemi Kan, Sumiko Kurioka, Takuro Shimb. Altered DNA methylation status of human brain derived neurotrophis factor gene could be useful as biomarker of depression. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 165B. issue 4. 2015-01-21. PMID:24801253. |
our results revealed significant changes in the dna methylation status of the complete human bdnf gene in persons with depression compared to normal individuals, especially in the promoter region of exon 1. |
2015-01-21 |
2023-08-13 |
human |
| Young-Min Park, Bun-Hee Lee, Tae Hyun Um, Sollip Ki. Serum BDNF levels in relation to illness severity, suicide attempts, and central serotonin activity in patients with major depressive disorder: a pilot study. PloS one. vol 9. issue 3. 2015-01-15. PMID:24663244. |
the subgroup with moderate-to-severe depression (n = 16) was reanalyzed after stratifying it into two subgroups according to ldaep and bdnf values (dichotomized at the medians into low and high). |
2015-01-15 |
2023-08-12 |
human |
| Amine Bahi, Vijay Chandrasekar, Jean-Luc Dreye. Selective lentiviral-mediated suppression of microRNA124a in the hippocampus evokes antidepressants-like effects in rats. Psychoneuroendocrinology. vol 46. 2015-01-06. PMID:24882160. |
several lines of evidences suggest that the brain-derived neutrophic factor (bdnf) is implicated in the pathophysiology of depression. |
2015-01-06 |
2023-08-13 |
rat |
| Anand Gururajan, Rachel Hill, Maarten van den Buus. Long-term differential effects of chronic young-adult corticosterone exposure on anxiety and depression-like behaviour in BDNF heterozygous rats depend on the experimental paradigm used. Neuroscience letters. vol 576. 2015-01-05. PMID:24907687. |
brain-derived neurotrophic factor (bdnf) has key roles in neurodevelopment and synaptic plasticity and is implicated in affective disorders such as anxiety and depression. |
2015-01-05 |
2023-08-13 |
rat |
| Ali Emrah Bilgen, Selma Bozkurt Zincir, Serkan Zincir, Barbaros Ozdemir, Mehmet Ak, Emre Aydemir, Irfan Sene. Effects of electroconvulsive therapy on serum levels of brain-derived neurotrophic factor and nerve growth factor in treatment resistant major depression. Brain research bulletin. vol 104. 2014-12-28. PMID:24747833. |
this study aimed to investigate the effects of electroconvulsive treatment on serum bdnf and ngf levels in patients with treatment-resistant major depression. |
2014-12-28 |
2023-08-13 |
Not clear |
| Go Suzuki, Shinichi Tokuno, Masashi Nibuya, Toru Ishida, Tetsuo Yamamoto, Yasuo Mukai, Keiji Mitani, Gentaro Tsumatori, Daniel Scott, Kunio Shimiz. Decreased plasma brain-derived neurotrophic factor and vascular endothelial growth factor concentrations during military training. PloS one. vol 9. issue 2. 2014-12-22. PMID:24586790. |
decreased concentrations of plasma brain-derived neurotrophic factor (bdnf) and serum bdnf have been proposed to be a state marker of depression and a biological indicator of loaded psychosocial stress. |
2014-12-22 |
2023-08-12 |
human |
| Laura L Hurley, Luli Akinfiresoye, Olubukola Kalejaiye, Yousef Tizab. Antidepressant effects of resveratrol in an animal model of depression. Behavioural brain research. vol 268. 2014-12-16. PMID:24717328. |
these findings indicate an antidepressant-like effect of resveratrol in an animal model of depression possibly via activation of hippocampal bdnf, and suggest therapeutic potential of resveratrol in at least a subpopulation of depressed patients. |
2014-12-16 |
2023-08-13 |
mouse |
| Arum Han, Yu-Bin Sung, Soo-Young Chung, Min-Soo Kwo. Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. Neuropharmacology. vol 81. 2014-12-15. PMID:24607816. |
however, it seems to be unsuccessful to prevent depression induction since reduction of pcreb, aceh3 and bdnf were accompanied by crs in the hippocampus. |
2014-12-15 |
2023-08-12 |
mouse |
| Jan Pláteník, Zdeněk Fišar, Richard Buchal, Roman Jirák, Eva Kitzlerová, Martina Zvěřová, Jiří Raboc. GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24334212. |
gsk3β, creb, and bdnf in peripheral blood of patients with alzheimer's disease and depression. |
2014-12-11 |
2023-08-12 |
Not clear |
| Swathi Gujral, Stephen B Manuck, Robert E Ferrell, Janine D Flory, Kirk I Erickso. The BDNF Val66Met polymorphism does not moderate the effect of self-reported physical activity on depressive symptoms in midlife. Psychiatry research. vol 218. issue 1-2. 2014-12-05. PMID:24745471. |
bdnf genotype, physical activity measured by the paffenbarger questionnaire, and depressive symptoms using the center for epidemiology depression scale (ces-d) were collected on 1072 participants (mean age=44). |
2014-12-05 |
2023-08-13 |
human |
| Zeliha Tunca, Aysegul Ozerdem, Deniz Ceylan, Yaprak Yalçın, Güneş Can, Halil Resmi, Pınar Akan, Gül Ergör, Omer Aydemir, Cengiz Cengisiz, Doyuran Keri. Alterations in BDNF (brain derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) serum levels in bipolar disorder: The role of lithium. Journal of affective disorders. vol 166. 2014-12-05. PMID:25012431. |
brain-derived neurotrophic factor (bdnf) has been consistently reported to be decreased in mania or depression in bipolar disorders. |
2014-12-05 |
2023-08-13 |
Not clear |
| Katarzyna Młyniec, Urszula Doboszewska, Bernadeta Szewczyk, Magdalena Sowa-Kućma, Paulina Misztak, Wojciech Piekoszewski, Franciszek Trela, Beata Ostachowicz, Gabriel Nowa. The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victims. Neuropharmacology. vol 79. 2014-12-03. PMID:24333148. |
down-regulation of creb, bdnf, trkb and gpr39 receptor found under zinc-deficient conditions in the hippocampus, may play an important role in the pathophysiology of mood disorders, since most of patients suffering from depression show lower serum zinc. |
2014-12-03 |
2023-08-12 |
mouse |
| Naoki Adachi, Tadahiro Numakawa, Misty Richards, Shingo Nakajima, Hiroshi Kunug. New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases. World journal of biological chemistry. vol 5. issue 4. 2014-11-26. PMID:25426265. |
we also introduce implications of bdnf in several brain-related diseases including alzheimer's disease, huntington's disease, depression and schizophrenia. |
2014-11-26 |
2023-08-13 |
Not clear |
| Lucian Hritcu, Lucian Dragos Gorga. Intranigral lipopolysaccharide induced anxiety and depression by altered BDNF mRNA expression in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 51. 2014-11-25. PMID:24508447. |
intranigral lipopolysaccharide induced anxiety and depression by altered bdnf mrna expression in rat hippocampus. |
2014-11-25 |
2023-08-12 |
rat |
| Annemarie van der Meij, Hannie C Comijs, Annemieke Dols, Joost G E Janzing, Richard C Oude Voshaa. BDNF in late-life depression: effect of SSRI usage and interaction with childhood abuse. Psychoneuroendocrinology. vol 43. 2014-11-24. PMID:24703173. |
bdnf in late-life depression: effect of ssri usage and interaction with childhood abuse. |
2014-11-24 |
2023-08-13 |
human |