| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong-Qiang Liu, Guo-Bao Su, Chang-Hong Duan, Jun-Hua Wang, Hai-Mei Liu, Nan Feng, Qing-Xi Wang, Xu-En Liu, Jie Zhan. Brain‑derived neurotrophic factor gene polymorphisms are associated with coronary artery disease‑related depression and antidepressant response. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25324022. |
the aim of the present study was to investigate the possible association between seven single nucleotide polymorphisms (snps) of the bdnf gene (snps; rs16917204, rs6265, rs7103873, rs16917237, rs56164415, rs13306221 and rs10767664) and coronary artery disease‑related depression (cad‑d). |
2015-06-19 |
2023-08-13 |
Not clear |
| Seiko Yasuda, Mitsuhiro Yoshida, Hirotaka Yamagata, Yasutake Iwanaga, Hiromi Suenaga, Kozo Ishikawa, Masako Nakano, Satoshi Okuyama, Yoshiko Furukawa, Shoei Furukawa, Toshizo Ishikaw. Imipramine ameliorates pain-related negative emotion via induction of brain-derived neurotrophic factor. Cellular and molecular neurobiology. vol 34. issue 8. 2015-06-10. PMID:25156823. |
brain-derived neurotrophic factor (bdnf) is a neuromodulator that reduces depression by regulating synaptic transmission. |
2015-06-10 |
2023-08-13 |
rat |
| Shoko Tsuchimine, Manabu Saito, Sunao Kaneko, Norio Yasui-Furukor. Decreased serum levels of polyunsaturated fatty acids and folate, but not brain-derived neurotrophic factor, in childhood and adolescent females with depression. Psychiatry research. vol 225. issue 1-2. 2015-05-26. PMID:25466229. |
evidence from observational studies suggests that there is an association among depression and brain-derived neurotrophic factor (bdnf), polyunsaturated fatty acids (pufas), and folate; however, this association has yet to be examined in childhood and adolescent depression. |
2015-05-26 |
2023-08-13 |
human |
| Shoko Tsuchimine, Manabu Saito, Sunao Kaneko, Norio Yasui-Furukor. Decreased serum levels of polyunsaturated fatty acids and folate, but not brain-derived neurotrophic factor, in childhood and adolescent females with depression. Psychiatry research. vol 225. issue 1-2. 2015-05-26. PMID:25466229. |
we measured the serum levels of bdnf, pufas, and folate of cases admitted to the hospital for depression (n=24) and compared it to that of controls (n=26). |
2015-05-26 |
2023-08-13 |
human |
| Rachel A Hill, Maren Klug, Szerenke Kiss Von Soly, Michele D Binder, Anthony J Hannan, Maarten van den Buus. Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling. Hippocampus. vol 24. issue 10. 2015-05-12. PMID:24802968. |
post-mortem studies have demonstrated reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus of schizophrenia and major depression patients. |
2015-05-12 |
2023-08-13 |
rat |
| M L Molendijk, P Spinhoven, M Polak, B A A Bus, B W J H Penninx, B M Elzing. Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484). Molecular psychiatry. vol 19. issue 7. 2015-04-15. PMID:23958957. |
serum bdnf concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (n=9484). |
2015-04-15 |
2023-08-12 |
Not clear |
| M L Molendijk, P Spinhoven, M Polak, B A A Bus, B W J H Penninx, B M Elzing. Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484). Molecular psychiatry. vol 19. issue 7. 2015-04-15. PMID:23958957. |
these findings are believed to reflect peripheral manifestations of the neurotrophin hypothesis, which states that depression is secondary to an altered expression of bdnf in the brain. |
2015-04-15 |
2023-08-12 |
Not clear |
| M L Molendijk, P Spinhoven, M Polak, B A A Bus, B W J H Penninx, B M Elzing. Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484). Molecular psychiatry. vol 19. issue 7. 2015-04-15. PMID:23958957. |
this motivated us to update the evidence on the aforementioned associations and, in addition, to compile the data on serum bdnf concentrations in relation to the symptom severity of depression. |
2015-04-15 |
2023-08-12 |
Not clear |
| M L Molendijk, P Spinhoven, M Polak, B A A Bus, B W J H Penninx, B M Elzing. Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484). Molecular psychiatry. vol 19. issue 7. 2015-04-15. PMID:23958957. |
finally, the aggregated data negate consistent associations between serum bdnf concentrations and the symptom severity of depression. |
2015-04-15 |
2023-08-12 |
Not clear |
| M L Molendijk, P Spinhoven, M Polak, B A A Bus, B W J H Penninx, B M Elzing. Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484). Molecular psychiatry. vol 19. issue 7. 2015-04-15. PMID:23958957. |
our findings corroborate the claim that altered serum bdnf concentrations are peripheral manifestations of depression. |
2015-04-15 |
2023-08-12 |
Not clear |
| Xin-Rui Qi, Jun Zhao, Ji Liu, Hui Fang, Dick F Swaab, Jiang-Ning Zho. Abnormal retinoid and TrkB signaling in the prefrontal cortex in mood disorders. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 1. 2015-04-06. PMID:23960204. |
retinoid signaling, brain-derived neurotrophic factor (bdnf), and its receptor trkb are reported to be involved in depression. |
2015-04-06 |
2023-08-12 |
human |
| Antonio Martocchia, Martina Curto, Sergio Scaccianoce, Fabrizia Comite, Dionysios Xenos, Carla Nasca, Giulia Maria Falaschi, Stefano Ferracuti, Paolo Girardi, Ferdinando Nicoletti, Paolo Falasch. Effects of escitalopram on serum BDNF levels in elderly patients with depression: a preliminary report. Aging clinical and experimental research. vol 26. issue 4. 2015-03-30. PMID:24435333. |
effects of escitalopram on serum bdnf levels in elderly patients with depression: a preliminary report. |
2015-03-30 |
2023-08-12 |
human |
| Sara Farhang, Jaleh Barar, Ali Fakhari, Mehran Mesgariabbasi, Sajjad Khani, Yadollah Omidi, Alireza Farna. Asymmetrical expression of BDNF and NTRK3 genes in frontoparietal cortex of stress-resilient rats in an animal model of depression. Synapse (New York, N.Y.). vol 68. issue 9. 2015-03-06. PMID:24753016. |
asymmetrical expression of bdnf and ntrk3 genes in frontoparietal cortex of stress-resilient rats in an animal model of depression. |
2015-03-06 |
2023-08-13 |
rat |
| Thorsten Mikoteit, Johannes Beck, Anne Eckert, Ulrich Hemmeter, Serge Brand, Roland Bischof, Edith Holsboer-Trachsler, Alexandra Delini-Stul. High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression. Psychopharmacology. vol 231. issue 15. 2015-03-03. PMID:24562062. |
high baseline bdnf serum levels and early psychopathological improvement are predictive of treatment outcome in major depression. |
2015-03-03 |
2023-08-12 |
Not clear |
| Yuan Hu, Xiao-Jiang Zhou, Ping Liu, Xian-Zhe Dong, Li-Hua Mu, Yi-Bang Chen, Ming-Yue Liu, Bing-Ying Y. Antidepressant and neuroprotective effect of the Chinese herb kaixinsan against lentiviral shRNA knockdown brain-derived neurotrophic factor-induced injury in vitro and in vivo. Neuropsychobiology. vol 69. issue 3. 2015-02-26. PMID:24776773. |
depression has been associated with reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2015-02-26 |
2023-08-13 |
Not clear |
| Yuan Hu, Xiao-Jiang Zhou, Ping Liu, Xian-Zhe Dong, Li-Hua Mu, Yi-Bang Chen, Ming-Yue Liu, Bing-Ying Y. Antidepressant and neuroprotective effect of the Chinese herb kaixinsan against lentiviral shRNA knockdown brain-derived neurotrophic factor-induced injury in vitro and in vivo. Neuropsychobiology. vol 69. issue 3. 2015-02-26. PMID:24776773. |
using bdnf knockdown mediated by lentiviral vectors (lv-shbdnf-3) transfected with primary hippocampal neurons and following injection into the dentate gyrus of the hippocampus, it was demonstrated that a reduction in bdnf expression affects cell viability and animal behaviours associated with depression. |
2015-02-26 |
2023-08-13 |
Not clear |
| Yuan Hu, Xiao-Jiang Zhou, Ping Liu, Xian-Zhe Dong, Li-Hua Mu, Yi-Bang Chen, Ming-Yue Liu, Bing-Ying Y. Antidepressant and neuroprotective effect of the Chinese herb kaixinsan against lentiviral shRNA knockdown brain-derived neurotrophic factor-induced injury in vitro and in vivo. Neuropsychobiology. vol 69. issue 3. 2015-02-26. PMID:24776773. |
these findings provide substantial evidence for supporting a neurotrophic hypothesis of depression and specify bdnf targets for potential antidepressant interventions. |
2015-02-26 |
2023-08-13 |
Not clear |
| Wu Hong, Jinbo Fan, Chengmei Yuan, Chen Zhang, Yingyan Hu, Daihui Peng, Yong Wang, Jia Huang, Zezhi Li, Shunying Yu, Xiaohua Liu, Zhiguo Wu, Jun Chen, Zhenghui Yi, Lin Xu, Yiru Fan. Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression. Neuroreport. vol 25. issue 10. 2015-02-20. PMID:24709918. |
significantly decreased mrna levels of bdnf and mek1 genes in treatment-resistant depression. |
2015-02-20 |
2023-08-13 |
Not clear |
| Wu Hong, Jinbo Fan, Chengmei Yuan, Chen Zhang, Yingyan Hu, Daihui Peng, Yong Wang, Jia Huang, Zezhi Li, Shunying Yu, Xiaohua Liu, Zhiguo Wu, Jun Chen, Zhenghui Yi, Lin Xu, Yiru Fan. Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression. Neuroreport. vol 25. issue 10. 2015-02-20. PMID:24709918. |
the aim of the current study was to investigate whether the levels of mrna expression of brain-derived neurotrophin factor (bdnf) and a related gene mek1 were more obviously decreased in treatment-resistant depression (trd). |
2015-02-20 |
2023-08-13 |
Not clear |
| Lun-Ching Chang, Stephane Jamain, Chien-Wei Lin, Dan Rujescu, George C Tseng, Etienne Sibill. A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies. PloS one. vol 9. issue 3. 2015-02-12. PMID:24608543. |
a conserved bdnf, glutamate- and gaba-enriched gene module related to human depression identified by coexpression meta-analysis and dna variant genome-wide association studies. |
2015-02-12 |
2023-08-12 |
human |