| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hee-Ju Kang, Jae-Min Kim, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Hye-Ran Kim, Myung-Geun Shin, Jin-Sang Yoo. Longitudinal associations between BDNF promoter methylation and late-life depression. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25648279. |
we investigated the independent and interactive effects of bdnf methylation and val66met polymorphism on late-life depression. |
2016-03-17 |
2023-08-13 |
Not clear |
| Hee-Ju Kang, Jae-Min Kim, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Hye-Ran Kim, Myung-Geun Shin, Jin-Sang Yoo. Longitudinal associations between BDNF promoter methylation and late-life depression. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25648279. |
the effects of bdnf methylation and polymorphism on the diagnosis of depression were investigated using a multivariate logistic regression model, and the relationships between bdnf methylation and depression severity were evaluated using partial correlation tests. |
2016-03-17 |
2023-08-13 |
Not clear |
| Hee-Ju Kang, Jae-Min Kim, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Hye-Ran Kim, Myung-Geun Shin, Jin-Sang Yoo. Longitudinal associations between BDNF promoter methylation and late-life depression. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25648279. |
higher bdnf methylation was independently associated with the prevalence and incidence of depression and severe depressive symptoms. |
2016-03-17 |
2023-08-13 |
Not clear |
| Hee-Ju Kang, Jae-Min Kim, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Hye-Ran Kim, Myung-Geun Shin, Jin-Sang Yoo. Longitudinal associations between BDNF promoter methylation and late-life depression. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25648279. |
bdnf promoter methylation could be a proxy biomarker for depression late in life. |
2016-03-17 |
2023-08-13 |
Not clear |
| L C Lin, E Sibill. Somatostatin, neuronal vulnerability and behavioral emotionality. Molecular psychiatry. vol 20. issue 3. 2016-03-03. PMID:25600109. |
here we show that mice lacking sst (sst(ko)) exhibit elevated behavioral emotionality, high basal plasma corticosterone and reduced gene expression of bdnf, cortistatin and gad67, together recapitulating behavioral, neuroendocrine and molecular features of human depression. |
2016-03-03 |
2023-08-13 |
mouse |
| Helmuth Haslacher, Matthias Michlmayr, Delgerdalai Batmyagmar, Thomas Perkmann, Elisabeth Ponocny-Seliger, Vanessa Scheichenberger, Alexander Pilger, Peter Dal-Bianco, Johann Lehrner, Lukas Pezawas, Oswald Wagner, Robert Winke. Physical exercise counteracts genetic susceptibility to depression. Neuropsychobiology. vol 71. issue 3. 2016-02-16. PMID:25998702. |
a genetic variant (rs6265) of the brain-derived neurotrophic factor (bdnf) impacting on emotion processing is known to increase the risk for depression. |
2016-02-16 |
2023-08-13 |
Not clear |
| Rebecca MacGregor Legge, Shahbaz Sendi, James H Cole, Sarah Cohen-Woods, Sergi G Costafreda, Andrew Simmons, Anne E Farmer, Katherine J Aitchison, Peter McGuffin, Cynthia H Y F. Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder. The British journal of psychiatry : the journal of mental science. vol 206. issue 5. 2016-02-04. PMID:25745134. |
brain-derived neurotrophic factor (bdnf) val66met polymorphism contributes to the development of depression (major depressive disorder, mdd), but it is unclear whether neural effects observed in healthy individuals are sustained in mdd. |
2016-02-04 |
2023-08-13 |
Not clear |
| Daniel Rial, Cristina Lemos, Helena Pinheiro, Joana M Duarte, Francisco Q Gonçalves, Joana I Real, Rui D Prediger, Nélio Gonçalves, Catarina A Gomes, Paula M Canas, Paula Agostinho, Rodrigo A Cunh. Depression as a Glial-Based Synaptic Dysfunction. Frontiers in cellular neuroscience. vol 9. 2016-02-02. PMID:26834566. |
furthermore, the traditional culprits of depression (glucocorticoids, biogenic amines, brain-derived neurotrophic factor, bdnf) affect glia functioning, whereas antidepressant treatments (serotonin-selective reuptake inhibitors, ssris, electroshocks, deep brain stimulation) recover glia functioning. |
2016-02-02 |
2023-08-13 |
Not clear |
| Liu Luo, Xiao-Long Liu, Rong-Hao Mu, Yong-Jing Wu, Bin-Bin Liu, Di Geng, Qing Liu, Li-Tao Y. Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice. Brain research bulletin. vol 114. 2016-01-26. PMID:25857945. |
brain-derived neurotrophic factor (bdnf) plays a key role in the regulation of depression in the brain. |
2016-01-26 |
2023-08-13 |
mouse |
| E C Braithwaite, M Kundakovic, P G Ramchandani, S E Murphy, F A Champagn. Maternal prenatal depressive symptoms predict infant NR3C1 1F and BDNF IV DNA methylation. Epigenetics. vol 10. issue 5. 2016-01-25. PMID:25875334. |
our findings highlight the susceptibility of males to changes in nr3c1 dna methylation and present novel evidence for altered bdnf iv dna methylation in response to maternal depression during pregnancy. |
2016-01-25 |
2023-08-13 |
human |
| Changwoo Han, Donghyun Ahn, Woong Hahm, Junghyun Nam, Yongchon Park, Seulgi Lim, Dai-Jin Ki. Serum Levels of Growth Factors in Alcohol-dependent Patients according to Comorbid Depressive Symptoms. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 14. issue 1. 2016-01-21. PMID:26792039. |
this study aims to reveal the relationship of depression with growth factors such as brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), and insulin-like growth factor-1 (igf-1) in inpatients diagnosed with alcohol dependence, and to identify candidate growth factors as biological markers to indicate the comorbid of alcohol dependence and depression. |
2016-01-21 |
2023-08-13 |
Not clear |
| B A A Bus, M L Molendijk, I Tendolkar, B W J H Penninx, J Prickaerts, B M Elzinga, R C O Voshaa. Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time. Molecular psychiatry. vol 20. issue 5. 2016-01-19. PMID:25155878. |
one of the leading neurobiological hypotheses on depression states that decreased expression of brain-derived neurotrophic factor (bdnf) contributes to depression. |
2016-01-19 |
2023-08-13 |
Not clear |
| B A A Bus, M L Molendijk, I Tendolkar, B W J H Penninx, J Prickaerts, B M Elzinga, R C O Voshaa. Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time. Molecular psychiatry. vol 20. issue 5. 2016-01-19. PMID:25155878. |
to investigate the longitudinal association between serum bdnf and depression, we measured serum bdnf, (current and past) depression status, use of antidepressants, and all potential covariates at baseline and after 2 years in 1751 individuals, consisting of patients with an incident (n=153), remitted (n=420) and persistent depression (n=310) and non-depressed controls (n=868). |
2016-01-19 |
2023-08-13 |
Not clear |
| B A A Bus, M L Molendijk, I Tendolkar, B W J H Penninx, J Prickaerts, B M Elzinga, R C O Voshaa. Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time. Molecular psychiatry. vol 20. issue 5. 2016-01-19. PMID:25155878. |
compared with non-depressed controls, persistently depressed and remitted patients had a steeper decrease of bdnf levels over time (-1.33 (p=0.001) and -0.97 ng ml(-1) (p=0.011), respectively), whereas bdnf reductions in patients with incident depression were similar to those in healthy controls. |
2016-01-19 |
2023-08-13 |
Not clear |
| B A A Bus, M L Molendijk, I Tendolkar, B W J H Penninx, J Prickaerts, B M Elzinga, R C O Voshaa. Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time. Molecular psychiatry. vol 20. issue 5. 2016-01-19. PMID:25155878. |
these findings suggest that bdnf not only contributes to depression, but that depression in turn may also contribute to low bdnf. |
2016-01-19 |
2023-08-13 |
Not clear |
| Michele Fornaro, Andrea Escelsior, Giulio Rocchi, Benedetta Conio, Paola Magioncalda, Valentina Marozzi, Andrea Presta, Bruno Sterlini, Paola Contini, Mario Amore, Pantaleo Fornaro, Matteo Martin. BDNF plasma levels variations in major depressed patients receiving duloxetine. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 36. issue 5. 2016-01-19. PMID:25501804. |
30 mdd patients and 32 healthy controls were assessed using hamilton depression scale (ham-d) and monitored for bdnf plasma levels at baseline, week 6 and week 12 of duloxetine treatment (60 mg/day) and at baseline, respectively. |
2016-01-19 |
2023-08-13 |
Not clear |
| Henriette N Buttenschøn, Leslie Foldager, Betina Elfving, Pia H P Poulsen, Rudolf Uher, Ole Mor. Neurotrophic factors in depression in response to treatment. Journal of affective disorders. vol 183. 2016-01-12. PMID:26047306. |
brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor a (vegf) have been suggested to play a role in the pathophysiology of depression. |
2016-01-12 |
2023-08-13 |
Not clear |
| Henriette N Buttenschøn, Leslie Foldager, Betina Elfving, Pia H P Poulsen, Rudolf Uher, Ole Mor. Neurotrophic factors in depression in response to treatment. Journal of affective disorders. vol 183. 2016-01-12. PMID:26047306. |
bdnf is decreased during depression and increased in response to treatment. |
2016-01-12 |
2023-08-13 |
Not clear |
| C F Jehn, B Becker, B Flath, H Nogai, L Vuong, P Schmid, D Lüftne. Neurocognitive function, brain-derived neurotrophic factor (BDNF) and IL-6 levels in cancer patients with depression. Journal of neuroimmunology. vol 287. 2016-01-08. PMID:26439967. |
neurocognitive function, brain-derived neurotrophic factor (bdnf) and il-6 levels in cancer patients with depression. |
2016-01-08 |
2023-08-13 |
Not clear |
| C F Jehn, B Becker, B Flath, H Nogai, L Vuong, P Schmid, D Lüftne. Neurocognitive function, brain-derived neurotrophic factor (BDNF) and IL-6 levels in cancer patients with depression. Journal of neuroimmunology. vol 287. 2016-01-08. PMID:26439967. |
increased il-6 and decreased brain-derived neurotrophic factor (bdnf) levels have been implicated in the pathophysiology of depression. |
2016-01-08 |
2023-08-13 |
Not clear |