| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gabriela Pandini Silote, Ariandra Sartim, Amanda Sales, Amanda Eskelund, F S Guimarães, Gregers Wegener, Samia Joc. Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. Journal of chemical neuroanatomy. vol 98. 2020-08-17. PMID:31039391. |
moreover, cbd induces cellular and molecular changes in brain regions related to depression neurobiology, such as increased brain derived neurotrophic factor (bdnf) levels and synaptogenesis in the medial prefrontal cortex, as well as it increases neurogenesis in the hippocampus. |
2020-08-17 |
2023-08-13 |
Not clear |
| Jae-Min Kim, Robert Stewart, Ju-Wan Kim, Hee-Ju Kang, Ju-Yeon Lee, Seon-Young Kim, Sung-Wan Kim, Il-Seon Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoo. Modifying effects of depression on the association between BDNF methylation and prognosis of acute coronary syndrome. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31255678. |
modifying effects of depression on the association between bdnf methylation and prognosis of acute coronary syndrome. |
2020-08-14 |
2023-08-13 |
Not clear |
| Jae-Min Kim, Robert Stewart, Ju-Wan Kim, Hee-Ju Kang, Ju-Yeon Lee, Seon-Young Kim, Sung-Wan Kim, Il-Seon Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoo. Modifying effects of depression on the association between BDNF methylation and prognosis of acute coronary syndrome. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31255678. |
we asked whether bdnf methylation status is associated with a major adverse cardiac event (mace), inflammation, and the association with depression comorbidity and its treatment in patients with acute coronary syndrome (acs). |
2020-08-14 |
2023-08-13 |
Not clear |
| Yi-Xi Wang, Xiao-Ning Kang, Yang Cao, De-Xiu Zheng, Ye-Ming Lu, Chun-Feng Pang, Zhi Wang, Bin Cheng, Yun Pen. Porphyromonas gingivalis induces depression via downregulating p75NTR-mediated BDNF maturation in astrocytes. Brain, behavior, and immunity. vol 81. 2020-08-14. PMID:31299366. |
porphyromonas gingivalis induces depression via downregulating p75ntr-mediated bdnf maturation in astrocytes. |
2020-08-14 |
2023-08-13 |
mouse |
| Bruk Getachew, Liliana Mendieta, Antonei B Csoka, José Aguilera, Yousef Tizab. Antidepressant effects of C-Terminal domain of the heavy chain of tetanus toxin in a rat model of depression. Behavioural brain research. vol 370. 2020-07-30. PMID:31125623. |
since depression is a common co-morbid condition with pd, we undertook this study to determine whether hc-tetx might also show antidepressant-like properties and whether central brain-derived neurotrophic factor (bdnf) and/or tumor necrosis factor (tnf)-alpha are also affected by it. |
2020-07-30 |
2023-08-13 |
rat |
| Taichi Ochi, Natalya M Vyalova, Innokentiy S Losenkov, Lyudmila A Levchuk, Diana Z Osmanova, Ekaterina V Mikhalitskaya, Anton J M Loonen, Fokko J Bosker, German G Simutkin, Nikolay A Bokhan, Bob Wilffert, Svetlana A Ivanov. Investigating the potential role of BDNF and PRL genotypes on antidepressant response in depression patients: A prospective inception cohort study in treatment-free patients. Journal of affective disorders. vol 259. 2020-07-22. PMID:31611000. |
investigating the potential role of bdnf and prl genotypes on antidepressant response in depression patients: a prospective inception cohort study in treatment-free patients. |
2020-07-22 |
2023-08-13 |
Not clear |
| Hélène Party, Cléo Dujarrier, Marie Hébert, Sophie Lenoir, Sara Martinez de Lizarrondo, Raphaël Delépée, Claudine Fauchon, Marie-Christine Bouton, Pauline Obiang, Olivier Godefroy, Etienne Save, Laurent Lecardeur, Joëlle Chabry, Denis Vivien, Véronique Agi. Plasminogen Activator Inhibitor-1 (PAI-1) deficiency predisposes to depression and resistance to treatments. Acta neuropathologica communications. vol 7. issue 1. 2020-07-13. PMID:31610810. |
we demonstrate here that pai-1 plays a key role in depression by a mechanism independent of the tissue-type plasminogen activator (tpa) - brain-derived neurotrophic factor (bdnf) axis, but associated with impaired metabolisms of serotonin and dopamine. |
2020-07-13 |
2023-08-13 |
mouse |
| Qin Gong, Xiao-Jin Yan, Fan Lei, Mu-Lan Wang, Lu-Ling He, Ying-Ying Luo, Hong-Wei Gao, Yu-Lin Feng, Shi-Lin Yang, Jun Li, Li-Jun D. Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation. Molecular brain. vol 12. issue 1. 2020-07-10. PMID:31888678. |
chronic corticosterone (cort) stress is an anxiety and depression inducing factor that involves the dysfunction of glucocorticoid receptor (gr), brain-derived neurotrophic factor (bdnf), and neuronal plasticity. |
2020-07-10 |
2023-08-13 |
mouse |
| Andrea László, Lilla Lénárt, Lilla Illésy, Andrea Fekete, János Nemcsi. The role of neurotrophins in psychopathology and cardiovascular diseases: psychosomatic connections. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 3. 2020-06-16. PMID:30767081. |
decreased level of bdnf is observed in depression and its connection to hypertension has also been demonstrated with affecting the arterial baroreceptors, renin-angiotensin system and endothelial nitric oxide synthase. |
2020-06-16 |
2023-08-13 |
human |
| Luana M Manosso, Morgana Moretti, Julia M Rosa, Mauricio P Cunha, Ana Lúcia S Rodrigue. Evidence for the involvement of heme oxygenase-1 in the antidepressant-like effect of zinc. Pharmacological reports : PR. vol 69. issue 3. 2020-06-03. PMID:31994098. |
considering that heme oxygenase-1 (ho-1) and the brain-derived neurotrophic factor (bdnf)-mediated pathway are involved in the pathophysiology of depression and that zinc has been shown to exert beneficial effects in the management of depression, this study investigated the influence of these targets on the antidepressant-like effect of zinc. |
2020-06-03 |
2023-08-13 |
Not clear |
| Andre R Brunoni, Angel Carracedo, Olalla M Amigo, Ana L Pellicer, Leda Talib, Andre F Carvalho, Paulo A Lotufo, Isabela M Benseñor, Wagner Gattaz, Carolina Capp. Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 42. issue 2. 2020-05-26. PMID:31721892. |
we investigated whether single nucleotide polymorphisms (snps) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (bdnf, rs6265), the serotonin transporter (slc6a4, rs25531), the tryptophan hydroxylase 1 (tph1, rs1800532), the 5-hydroxytryptamine receptor 2a (htr2a, rs6311, rs6313, rs7997012), and the catechol-o-methyltransferase (comt, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tdcs) in major depression. |
2020-05-26 |
2023-08-13 |
Not clear |
| Jodi L Pawluski, Ursula Brain, Geoffrey L Hammond, Tim F Oberlande. Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression. Archives of women's mental health. vol 22. issue 3. 2020-05-11. PMID:30506371. |
using a cohort of 86 pregnant women, we found that ssris significantly increase bdnf levels in late pregnancy and that s100b, but not bdnf, is associated with maternal depression in ssri-treated women only. |
2020-05-11 |
2023-08-13 |
Not clear |
| Madhumita Ghosh, Akhtar Ali, Shobhna Joshi, Adya Shankar Srivastava, Madhu G Tapadi. SLC1A3 C3590T but not BDNF G196A is a predisposition factor for stress as well as depression, in an adolescent eastern Indian population. BMC medical genetics. vol 21. issue 1. 2020-05-04. PMID:32171272. |
the present study was undertaken to test whether the known polymorphisms slc1a3 c3590t, slc1a3 c869g and bdnf g196a are associated or not with stress or depression in an eastern indian population. |
2020-05-04 |
2023-08-13 |
Not clear |
| M Dimitriadis, R H S van den Brink, H C Comijs, R C Oude Voshaa. Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage? Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771710. |
prognostic effect of serum bdnf levels in late-life depression: moderated by childhood trauma and ssri usage? |
2020-04-23 |
2023-08-13 |
Not clear |
| M Dimitriadis, R H S van den Brink, H C Comijs, R C Oude Voshaa. Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage? Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771710. |
brain-derived neurotrophic factor (bdnf) levels decline during depression and normalise after remission, although studies in older patient samples are inconsistent. |
2020-04-23 |
2023-08-13 |
Not clear |
| M Dimitriadis, R H S van den Brink, H C Comijs, R C Oude Voshaa. Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage? Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771710. |
whether bdnf serum levels predict depression remission is unclear. |
2020-04-23 |
2023-08-13 |
Not clear |
| M Dimitriadis, R H S van den Brink, H C Comijs, R C Oude Voshaa. Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage? Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771710. |
we hypothesize that the predictive value of serum bdnf levels in late-life depression is moderated by selective serotonin reuptake inhibitors (ssri) usage and early traumatization. |
2020-04-23 |
2023-08-13 |
Not clear |
| Lilla Lenart, Dora B Balogh, Nikolett Lenart, Adrienn Barczi, Adam Hosszu, Tamas Farkas, Judit Hodrea, Attila J Szabo, Krisztian Szigeti, Adam Denes, Andrea Feket. Novel therapeutic potential of angiotensin receptor 1 blockade in a rat model of diabetes-associated depression parallels altered BDNF signalling. Diabetologia. vol 62. issue 8. 2020-04-16. PMID:31053872. |
novel therapeutic potential of angiotensin receptor 1 blockade in a rat model of diabetes-associated depression parallels altered bdnf signalling. |
2020-04-16 |
2023-08-13 |
rat |
| Hong-Yi He, Jin-Lan Tian, Yong-Qiong Deng, Xia Xiong, Yang Xu, Yong-Mei Liao, Jing Fang, Xia Feng, Xin Ye, Chang-Qiang L. Association of brain-derived neurotrophic factor levels and depressive symptoms in young adults with acne vulgaris. BMC psychiatry. vol 19. issue 1. 2020-03-30. PMID:31234814. |
brain-derived neurotrophic factor (bdnf) is one of the proteins that contributes to the survival, growth, maintenance of neurons, and plays important roles in the pathophysiology of depression. |
2020-03-30 |
2023-08-13 |
Not clear |
| Victor Celso Cavalcanti Capibaribe, Auriana Serra Vasconcelos Mallmann, Iardja Stéfane Lopes, Iris Cristina Maia Oliveira, Natalia Ferreira de Oliveira, Raquell de Castro Chaves, Mariana Lima Fernandes, Mariana Albuquerque de Araujo, Daniel Moreira Alves da Silva, José Tiago Valentim, Adriano José Maia Chaves Filho, Danielle Silveira Macêdo, Silvânia Maria Mendes de Vasconcelos, Alyne Mara Rodrigues de Carvalho, Francisca Cléa Florenço de Sous. Thymol reverses depression-like behaviour and upregulates hippocampal BDNF levels in chronic corticosterone-induced depression model in female mice. The Journal of pharmacy and pharmacology. vol 71. issue 12. 2020-03-27. PMID:31608449. |
thymol reverses depression-like behaviour and upregulates hippocampal bdnf levels in chronic corticosterone-induced depression model in female mice. |
2020-03-27 |
2023-08-13 |
mouse |