Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Brittni K Novak, Keisha D Novak, Donald R Lynam, Dan Fot. Individual differences in the time course of reward processing: Stage-specific links with depression and impulsivity. Biological psychology. vol 119. 2017-09-13. PMID:27396750. |
individual differences in the time course of reward processing: stage-specific links with depression and impulsivity. |
2017-09-13 |
2023-08-13 |
Not clear |
Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. |
2017-09-11 |
2023-08-13 |
human |
Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
however, whether abnormal reward circuits affect cognition and depression in mdd patients remains unclear. |
2017-09-11 |
2023-08-13 |
human |
Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
a multivariate linear regression analysis was employed to investigate the neural substrates of cognitive function and depression severity on the reward circuits in mdd patients. |
2017-09-11 |
2023-08-13 |
human |
Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
importantly, distinct and common neural pathways underlying cognition and depression were identified, implying the independent and synergistic effects of cognitive deficits and depression severity on reward circuits. |
2017-09-11 |
2023-08-13 |
human |
Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
this study demonstrated that disrupted topological organization within reward circuits was significantly associated with cognitive deficits and depression severity in mdd patients. |
2017-09-11 |
2023-08-13 |
human |
Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai, Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang, Chunming Xie, Zhijun Zhan. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27673704. |
these findings suggest that in addition to antidepressant treatment, normalized reward circuits should be a focus and a target for improving depression and cognitive deficits in mdd patients. |
2017-09-11 |
2023-08-13 |
human |
J C Felger, Z Li, E Haroon, B J Woolwine, M Y Jung, X Hu, A H Mille. Inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depression. Molecular psychiatry. vol 21. issue 10. 2017-09-05. PMID:26552591. |
inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depression. |
2017-09-05 |
2023-08-13 |
Not clear |
J C Felger, Z Li, E Haroon, B J Woolwine, M Y Jung, X Hu, A H Mille. Inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depression. Molecular psychiatry. vol 21. issue 10. 2017-09-05. PMID:26552591. |
depression is associated with alterations in corticostriatal reward circuitry. |
2017-09-05 |
2023-08-13 |
Not clear |
J C Felger, Z Li, E Haroon, B J Woolwine, M Y Jung, X Hu, A H Mille. Inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depression. Molecular psychiatry. vol 21. issue 10. 2017-09-05. PMID:26552591. |
accordingly, we examined whether increased inflammation in depression affects corticostriatal reward circuitry to lead to deficits in motivation and goal-directed motor behavior. |
2017-09-05 |
2023-08-13 |
Not clear |
Shuntaro Kohnomi, Katsuko Ebihara, Masayuki Kobayash. Suppressive regulation of lateral inhibition between medium spiny neurons via dopamine D Neuroscience letters. vol 636. 2017-08-24. PMID:27793700. |
suppressive regulation of lateral inhibition between medium spiny neurons via dopamine d the nucleus accumbens (nac) shell is closely associated with reward, psychiatric disorders (depression or schizophrenia), and drug abuse. |
2017-08-24 |
2023-08-13 |
Not clear |
Alexandre Zénon, Sophie Devesse, Etienne Olivie. Dopamine Manipulation Affects Response Vigor Independently of Opportunity Cost. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 37. 2017-08-22. PMID:27629704. |
dopamine is known to be involved in regulating effort investment in relation to reward, and the disruption of this mechanism is thought to be central in some pathological situations such as parkinson's disease, addiction, and depression. |
2017-08-22 |
2023-08-13 |
human |
Akina Umemoto, Clay B Holroy. Neural mechanisms of reward processing associated with depression-related personality traits. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 128. issue 7. 2017-08-21. PMID:28521266. |
although impaired reward processing in depression has been well-documented, the exact nature of that deficit remains poorly understood. |
2017-08-21 |
2023-08-13 |
Not clear |
Akina Umemoto, Clay B Holroy. Neural mechanisms of reward processing associated with depression-related personality traits. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 128. issue 7. 2017-08-21. PMID:28521266. |
to investigate the link between depression and the neural mechanisms of reward processing, we examined individual differences in personality. |
2017-08-21 |
2023-08-13 |
Not clear |
Hee-Dae Kim, Jennifer Hesterman, Tanessa Call, Samantha Magazu, Elizabeth Keeley, Kristyna Armenta, Hope Kronman, Rachael L Neve, Eric J Nestler, Deveroux Ferguso. SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 32. 2017-07-14. PMID:27511015. |
in the present study, we show that chronic social defeat stress, an ethologically validated model of depression in mice, increases sirt1 levels in the nucleus accumbens (nac), a key brain reward region. |
2017-07-14 |
2023-08-13 |
mouse |
Takahiro Kato, Soichiro Ide, Masabumi Minam. Pain relief induces dopamine release in the rat nucleus accumbens during the early but not late phase of neuropathic pain. Neuroscience letters. vol 629. 2017-06-29. PMID:27369326. |
the neuronal pathway from the ventral tegmental area to the nucleus accumbens (nac) is critical in the mesolimbic dopamine (da) reward circuit, and dysfunction of this pathway has been implicated in depression. |
2017-06-29 |
2023-08-13 |
rat |
Jaak Panksep. The Psycho-Neurology of Cross-Species Affective/Social Neuroscience: Understanding Animal Affective States as a Guide to Development of Novel Psychiatric Treatments. Current topics in behavioral neurosciences. vol 30. 2017-06-22. PMID:27696337. |
its genesis is significantly influenced by (i) sustained overactivity of the separation-distress panic system reflecting severed social bonds and the excessive "psychological pain" of loneliness that can, if sustained, lead to a downward cascade known as psychological despair, and (ii) the despair phase that follows the acute panic response, which is characterized by abnormally low activity of the seeking, the so-called brain reward networks, leading to amotivational states that characterize depression. |
2017-06-22 |
2023-08-13 |
human |
Jennifer C Felge. The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications. Current topics in behavioral neurosciences. vol 31. 2017-06-20. PMID:27225499. |
similar relationships between alterations in dopamine-relevant corticostriatal reward circuitry and symptoms of anhedonia and psychomotor slowing have also been observed in patients with major depression who exhibit increased peripheral cytokines and other inflammatory markers, such as c-reactive protein. |
2017-06-20 |
2023-08-13 |
Not clear |
Joseph P Huston, Johannes Kornhuber, Christiane Mühle, Lukasz Japtok, Mara Komorowski, Claudia Mattern, Martin Reichel, Erich Gulbins, Burkhard Kleuser, Bianca Topic, Maria A De Souza Silva, Christian P Mülle. A sphingolipid mechanism for behavioral extinction. Journal of neurochemistry. vol 137. issue 4. 2017-06-05. PMID:26788861. |
failure to adapt to changes in reward contingencies may incur psychiatric disorders like anxiety and depression. |
2017-06-05 |
2023-08-13 |
rat |
Belel Ait Oumeziane, Dan Fot. Reward-related neural dysfunction across depression and impulsivity: A dimensional approach. Psychophysiology. vol 53. issue 8. 2017-05-24. PMID:27193188. |
significant interactions were observed between depression and impulsivity facets across these two stages of reward processing: depression and positive urgency predicted rewp amplitude to reward outcomes (win vs. loss); depression and one other impulsivity trait, (lack of) premeditation, predicted p3 amplitude to monetary outcomes. |
2017-05-24 |
2023-08-13 |
Not clear |