| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karolina Janacsek, Emőke Borbély-Ipkovich, Dezso Nemeth, Xénia Gond. How can the depressed mind extract and remember predictive relationships of the environment? Evidence from implicit probabilistic sequence learning. Progress in neuro-psychopharmacology & biological psychiatry. vol 81. 2018-06-27. PMID:28958916. |
these results cannot be explained by alterations in motivation, attention and reward processing but suggest more profound impairments of implicit learning and retention of predictive relationships among neutral stimuli in depression. |
2018-06-27 |
2023-08-13 |
Not clear |
| Marta Peciña, Magdalena Sikora, Erich T Avery, Joseph Heffernan, Susana Peciña, Brian J Mickey, Jon-Kar Zubiet. Striatal dopamine D2/3 receptor-mediated neurotransmission in major depression: Implications for anhedonia, anxiety and treatment response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 27. issue 10. 2018-05-30. PMID:28870407. |
dopamine (da) neurotransmission within the brain's reward circuit has been implicated in the pathophysiology of depression and in both, cognitive and pharmacological mechanisms of treatment response. |
2018-05-30 |
2023-08-13 |
Not clear |
| Wen-Hua Liu, Vincent Valton, Ling-Zhi Wang, Yu-Hua Zhu, Jonathan P Roise. Association between habenula dysfunction and motivational symptoms in unmedicated major depressive disorder. Social cognitive and affective neuroscience. vol 12. issue 9. 2018-05-24. PMID:28575424. |
the lateral habenula plays a central role in reward and punishment processing and has been suggested to drive the cardinal symptom of anhedonia in depression. |
2018-05-24 |
2023-08-13 |
human |
| Kerstin Brinkmann, Jessica Franze. Blunted cardiovascular reactivity during social reward anticipation in subclinical depression. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 119. 2018-05-10. PMID:28130127. |
the present study extends past research about reduced reward responsiveness in depression by assessing effort-related cardiovascular responses during anticipation of a social reward. |
2018-05-10 |
2023-08-13 |
human |
| Katherine R Luking, David Pagliaccio, Joan L Luby, Deanna M Barc. Reward Processing and Risk for Depression Across Development. Trends in cognitive sciences. vol 20. issue 6. 2018-04-12. PMID:27131776. |
reward processing and risk for depression across development. |
2018-04-12 |
2023-08-13 |
Not clear |
| Sayori Yashiro, Kenjiro Sek. Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain. Stress (Amsterdam, Netherlands). vol 20. issue 4. 2018-03-26. PMID:28554247. |
anhedonia is a core symptom of social defeat stress (sds)-induced depression associated with the reward system. |
2018-03-26 |
2023-08-13 |
mouse |
| Saki Minami, Hiroshi Satoyoshi, Soichiro Ide, Takeshi Inoue, Mitsuhiro Yoshioka, Masabumi Minam. Suppression of reward-induced dopamine release in the nucleus accumbens in animal models of depression: Differential responses to drug treatment. Neuroscience letters. vol 650. 2018-03-19. PMID:28432029. |
we investigated reward (30% sucrose intake)-induced da release in the nucleus accumbens (nac) and the effect of chronic treatment with the antidepressant escitalopram (5mg/kg, intraperitoneally twice daily for 3 weeks) in two animal models of depression. |
2018-03-19 |
2023-08-13 |
Not clear |
| Xi Zhu, Liat Helpman, Santiago Papini, Franklin Schneier, John C Markowitz, Page E Van Meter, Martin A Lindquist, Tor D Wager, Yuval Neri. Altered resting state functional connectivity of fear and reward circuitry in comorbid PTSD and major depression. Depression and anxiety. vol 34. issue 7. 2018-03-13. PMID:28030757. |
altered resting state functional connectivity of fear and reward circuitry in comorbid ptsd and major depression. |
2018-03-13 |
2023-08-13 |
Not clear |
| J J Walsh, M H Ha. The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience. vol 282. 2018-01-26. PMID:24931766. |
the ventral tegmental area (vta) in the brain's reward circuitry is composed of a heterogeneous population of dopamine, gaba, and glutamate neurons that play important roles in mediating mood-related functions including depression. |
2018-01-26 |
2023-08-13 |
Not clear |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
greater reward reactivity across behavioral and neurobiological measures moderated the association of maltreatment with baseline depression. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
specifically, faster reaction time (rt) to cues paired with monetary reward relative to those unpaired with reward and greater bold signal in the left pallidum was associated with lower depression symptoms in maltreated youth. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
longitudinally, greater bold signal in the left putamen moderated change in depression scores over time, such that higher levels of reward response were associated with lower increases in depression over time among maltreated youths. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
reactivity to monetary reward and positive social images, at both behavioral and neurobiological levels, is a potential marker of resilience to depression among adolescents exposed to maltreatment. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
these findings add to a growing body of work highlighting individual differences in reactivity to reward as a core neurodevelopmental mechanism in the etiology of depression. |
2018-01-25 |
2023-08-13 |
human |
| Erin Walsh, Hannah Carl, Tory Eisenlohr-Moul, Jared Minkel, Andrew Crowther, Tyler Moore, Devin Gibbs, Chris Petty, Josh Bizzell, Moria J Smoski, Gabriel S Dichte. Attenuation of Frontostriatal Connectivity During Reward Processing Predicts Response to Psychotherapy in Major Depressive Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27585739. |
in the present investigation, we examined pretreatment functional brain connectivity during reward processing as a potential predictor of response to behavioral activation treatment for depression (batd), a validated psychotherapy that promotes engagement with rewarding stimuli and reduces avoidance behaviors. |
2018-01-19 |
2023-08-13 |
human |
| Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27711046. |
histone lysine demethylases of jmjd2 or kdm4 family are important epigenetic regulators in reward circuitry in the etiopathology of depression. |
2018-01-19 |
2023-08-13 |
mouse |
| Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27711046. |
recent research shows dysregulation in epigenetic regulatory mechanisms, particularly the transcriptionally repressive di- and tri-methylation of histone 3 lysine 9 (h3k9me2/me3) in nucleus accumbens (nac), a critical region of the reward pathway involved in the development of anhedonia, the hallmark of depression. |
2018-01-19 |
2023-08-13 |
mouse |
| Giorgio Bergamini, Flurin Cathomas, Sandra Auer, Hannes Sigrist, Erich Seifritz, Michael Patterson, Cecilia Gabriel, Christopher R Pryc. Mouse psychosocial stress reduces motivation and cognitive function in operant reward tests: A model for reward pathology with effects of agomelatine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 9. 2018-01-18. PMID:27422761. |
a major domain of depression is decreased motivation for reward. |
2018-01-18 |
2023-08-13 |
mouse |
| Benjamin A Ely, Junqian Xu, Wayne K Goodman, Kyle A Lapidus, Vilma Gabbay, Emily R Ster. Resting-state functional connectivity of the human habenula in healthy individuals: Associations with subclinical depression. Human brain mapping. vol 37. issue 7. 2018-01-16. PMID:26991474. |
the habenula (hb) is postulated to play a critical role in reward and aversion processing across species, including humans, and has been increasingly implicated in depression. |
2018-01-16 |
2023-08-13 |
human |
| Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Gonzalo Arrondo, Trevor W Robbins, Luke Clark, Paul C Fletcher, Graham K Murra. Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26708106. |
abnormal frontostriatal activity during unexpected reward receipt in depression and schizophrenia: relationship to anhedonia. |
2018-01-15 |
2023-08-13 |
human |