| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J J Walsh, M H Ha. The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience. vol 282. 2018-01-26. PMID:24931766. |
the ventral tegmental area (vta) in the brain's reward circuitry is composed of a heterogeneous population of dopamine, gaba, and glutamate neurons that play important roles in mediating mood-related functions including depression. |
2018-01-26 |
2023-08-13 |
Not clear |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
greater reward reactivity across behavioral and neurobiological measures moderated the association of maltreatment with baseline depression. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
specifically, faster reaction time (rt) to cues paired with monetary reward relative to those unpaired with reward and greater bold signal in the left pallidum was associated with lower depression symptoms in maltreated youth. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
longitudinally, greater bold signal in the left putamen moderated change in depression scores over time, such that higher levels of reward response were associated with lower increases in depression over time among maltreated youths. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
reactivity to monetary reward and positive social images, at both behavioral and neurobiological levels, is a potential marker of resilience to depression among adolescents exposed to maltreatment. |
2018-01-25 |
2023-08-13 |
human |
| Meg J Dennison, Margaret A Sheridan, Daniel S Busso, Jessica L Jenness, Matthew Peverill, Maya L Rosen, Katie A McLaughli. Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse. Journal of abnormal psychology. vol 125. issue 8. 2018-01-25. PMID:27819477. |
these findings add to a growing body of work highlighting individual differences in reactivity to reward as a core neurodevelopmental mechanism in the etiology of depression. |
2018-01-25 |
2023-08-13 |
human |
| Erin Walsh, Hannah Carl, Tory Eisenlohr-Moul, Jared Minkel, Andrew Crowther, Tyler Moore, Devin Gibbs, Chris Petty, Josh Bizzell, Moria J Smoski, Gabriel S Dichte. Attenuation of Frontostriatal Connectivity During Reward Processing Predicts Response to Psychotherapy in Major Depressive Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27585739. |
in the present investigation, we examined pretreatment functional brain connectivity during reward processing as a potential predictor of response to behavioral activation treatment for depression (batd), a validated psychotherapy that promotes engagement with rewarding stimuli and reduces avoidance behaviors. |
2018-01-19 |
2023-08-13 |
human |
| Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27711046. |
histone lysine demethylases of jmjd2 or kdm4 family are important epigenetic regulators in reward circuitry in the etiopathology of depression. |
2018-01-19 |
2023-08-13 |
mouse |
| Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27711046. |
recent research shows dysregulation in epigenetic regulatory mechanisms, particularly the transcriptionally repressive di- and tri-methylation of histone 3 lysine 9 (h3k9me2/me3) in nucleus accumbens (nac), a critical region of the reward pathway involved in the development of anhedonia, the hallmark of depression. |
2018-01-19 |
2023-08-13 |
mouse |
| Giorgio Bergamini, Flurin Cathomas, Sandra Auer, Hannes Sigrist, Erich Seifritz, Michael Patterson, Cecilia Gabriel, Christopher R Pryc. Mouse psychosocial stress reduces motivation and cognitive function in operant reward tests: A model for reward pathology with effects of agomelatine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 9. 2018-01-18. PMID:27422761. |
a major domain of depression is decreased motivation for reward. |
2018-01-18 |
2023-08-13 |
mouse |
| Benjamin A Ely, Junqian Xu, Wayne K Goodman, Kyle A Lapidus, Vilma Gabbay, Emily R Ster. Resting-state functional connectivity of the human habenula in healthy individuals: Associations with subclinical depression. Human brain mapping. vol 37. issue 7. 2018-01-16. PMID:26991474. |
the habenula (hb) is postulated to play a critical role in reward and aversion processing across species, including humans, and has been increasingly implicated in depression. |
2018-01-16 |
2023-08-13 |
human |
| Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Gonzalo Arrondo, Trevor W Robbins, Luke Clark, Paul C Fletcher, Graham K Murra. Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26708106. |
abnormal frontostriatal activity during unexpected reward receipt in depression and schizophrenia: relationship to anhedonia. |
2018-01-15 |
2023-08-13 |
human |
| Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Gonzalo Arrondo, Trevor W Robbins, Luke Clark, Paul C Fletcher, Graham K Murra. Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26708106. |
alterations in reward processes may underlie motivational and anhedonic symptoms in depression and schizophrenia. |
2018-01-15 |
2023-08-13 |
human |
| Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Gonzalo Arrondo, Trevor W Robbins, Luke Clark, Paul C Fletcher, Graham K Murra. Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26708106. |
there was reduced activation in the orbitofrontal cortex, ventral striatum, inferior temporal gyrus, and occipital cortex in both depression and schizophrenia in comparison with healthy participants during receipt of unexpected reward. |
2018-01-15 |
2023-08-13 |
human |
| Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Gonzalo Arrondo, Trevor W Robbins, Luke Clark, Paul C Fletcher, Graham K Murra. Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26708106. |
our findings provide evidence for overlapping hypofunction in ventral striatal and orbitofrontal regions in depression and schizophrenia during unexpected reward receipt, and for a relationship between unexpected reward processing in the medial prefrontal cortex and the generation of motivational states. |
2018-01-15 |
2023-08-13 |
human |
| Ewelina Rzepa, Jennifer Fisk, Ciara McCab. Blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology. Journal of psychopharmacology (Oxford, England). vol 31. issue 3. 2018-01-04. PMID:28093022. |
blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology. |
2018-01-04 |
2023-08-13 |
Not clear |
| Ewelina Rzepa, Jennifer Fisk, Ciara McCab. Blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology. Journal of psychopharmacology (Oxford, England). vol 31. issue 3. 2018-01-04. PMID:28093022. |
neural reward function has been proposed as a possible biomarker for depression. |
2018-01-04 |
2023-08-13 |
Not clear |
| Ewelina Rzepa, Jennifer Fisk, Ciara McCab. Blunted neural response to anticipation, effort and consummation of reward and aversion in adolescents with depression symptomatology. Journal of psychopharmacology (Oxford, England). vol 31. issue 3. 2018-01-04. PMID:28093022. |
however, how the neural response to reward and aversion might differ in young adolescents with current symptoms of depression is as yet unclear. |
2018-01-04 |
2023-08-13 |
Not clear |
| Hailan H. Reward and Aversion. Annual review of neuroscience. vol 39. 2018-01-03. PMID:27145915. |
maladaptive changes in the neuromodulatory systems and neural circuits for reward and aversion can lead to manifestation of several prominent psychiatric disorders including addiction and depression. |
2018-01-03 |
2023-08-13 |
Not clear |
| Ciara McCab. Neural signals of 'intensity' but not 'wanting' or 'liking' of rewards may be trait markers for depression. Journal of psychopharmacology (Oxford, England). vol 30. issue 10. 2017-12-28. PMID:27296275. |
we have shown previously that participants 'at risk' of depression have decreased neural processing of reward suggesting this might be a neural biomarker for depression. |
2017-12-28 |
2023-08-13 |
human |