| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zachary S Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M Walker, Eric M Parise, Marine Salery, Michael E Cahill, Georgia E Hodes, Madeline L Pfau, Hope Kronman, Peter J Hamilton, Orna Issler, Benoit Labonté, Ann E Symonds, Matthew Zucker, Tie Yuan Zhang, Michael J Meaney, Scott J Russo, Li Shen, Rosemary C Bagot, Eric J Nestle. Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29549264. |
we identify estrogen receptor α (erα) as the top regulator of pro-resilient transcriptional changes in the nucleus accumbens (nac), a key brain reward region implicated in depression. |
2018-12-11 |
2023-08-13 |
mouse |
| Zuzana Hajasova, Corinne Canestrelli, Francine Acher, Florence Noble, Nicolas Mari. Role of mGlu7 receptor in morphine rewarding effects is uncovered by a novel orthosteric agonist. Neuropharmacology. vol 131. 2018-11-19. PMID:29307544. |
we also found that lsp2-9166 at the dose active for blocking morphine reward was devoid of any effect on locomotion, hedonic state, spatial memory, anxiety or depression. |
2018-11-19 |
2023-08-13 |
Not clear |
| Dongil Chung, Kelly Kadlec, Jason A Aimone, Katherine McCurry, Brooks King-Casas, Pearl H Chi. Valuation in major depression is intact and stable in a non-learning environment. Scientific reports. vol 7. 2018-11-08. PMID:28281665. |
in particular, various studies have shown blunted neural and behavioral responses to the experience of reward in depression. |
2018-11-08 |
2023-08-13 |
human |
| Dongil Chung, Kelly Kadlec, Jason A Aimone, Katherine McCurry, Brooks King-Casas, Pearl H Chi. Valuation in major depression is intact and stable in a non-learning environment. Scientific reports. vol 7. 2018-11-08. PMID:28281665. |
however, little is known about whether depression affects individuals' valuation of potential rewards during decision-making, independent from reward experience. |
2018-11-08 |
2023-08-13 |
human |
| Juhwan Kim, Sueun Lee, Sohi Kang, Tae-Il Jeon, Man-Jong Kang, Tae-Hoon Lee, Yong Sik Kim, Key-Sun Kim, Heh-In Im, Changjong Moo. Regulator of G-Protein Signaling 4 (RGS4) Controls Morphine Reward by Glutamate Receptor Activation in the Nucleus Accumbens of Mouse Brain. Molecules and cells. vol 41. issue 5. 2018-10-30. PMID:29754475. |
crosstalk between g-protein signaling and glutamatergic transmission within the brain reward circuits is critical for long-term emotional effects (depression and anxiety), cravings, and negative withdrawal symptoms associated with opioid addiction. |
2018-10-30 |
2023-08-13 |
mouse |
| Brady D Nelson, Ellen M Kessel, Daniel N Klein, Stewart A Shankma. Depression symptom dimensions and asymmetrical frontal cortical activity while anticipating reward. Psychophysiology. vol 55. issue 1. 2018-08-15. PMID:28555883. |
depression symptom dimensions and asymmetrical frontal cortical activity while anticipating reward. |
2018-08-15 |
2023-08-13 |
human |
| Brady D Nelson, Ellen M Kessel, Daniel N Klein, Stewart A Shankma. Depression symptom dimensions and asymmetrical frontal cortical activity while anticipating reward. Psychophysiology. vol 55. issue 1. 2018-08-15. PMID:28555883. |
the present study examined the association between multiple depression symptom dimensions and asymmetrical frontal cortical activity while anticipating reward in separate undergraduate (n = 75) and clinical samples (current major depressive disorder [n = 68] and never depressed controls [n = 67]). |
2018-08-15 |
2023-08-13 |
human |
| Brady D Nelson, Ellen M Kessel, Daniel N Klein, Stewart A Shankma. Depression symptom dimensions and asymmetrical frontal cortical activity while anticipating reward. Psychophysiology. vol 55. issue 1. 2018-08-15. PMID:28555883. |
in undergraduates with low depression symptoms and never depressed controls, reward trials relative to no-incentive trials elicited greater relative left frontal cortical activity. |
2018-08-15 |
2023-08-13 |
human |
| Anton J M Loonen, Svetlana A Ivanov. Commentary on "A non-reward attractor theory of depression": A proposal to include the habenula connection. Neuroscience and biobehavioral reviews. vol 83. 2018-07-20. PMID:28232092. |
the non-reward attractor theory of depression describes this mood disorder as originating from a neuronal dysfunction that arises from increased vulnerability of a cortical network that detects failure to receive an expected reward. |
2018-07-20 |
2023-08-13 |
Not clear |
| Michael S Gaffrey, Deanna M Barch, Ryan Bogdan, Katrina Farris, Steven E Petersen, Joan L Lub. Amygdala Reward Reactivity Mediates the Association Between Preschool Stress Response and Depression Severity. Biological psychiatry. vol 83. issue 2. 2018-07-17. PMID:29102026. |
amygdala reward reactivity mediates the association between preschool stress response and depression severity. |
2018-07-17 |
2023-08-13 |
Not clear |
| Michael S Gaffrey, Deanna M Barch, Ryan Bogdan, Katrina Farris, Steven E Petersen, Joan L Lub. Amygdala Reward Reactivity Mediates the Association Between Preschool Stress Response and Depression Severity. Biological psychiatry. vol 83. issue 2. 2018-07-17. PMID:29102026. |
however, very little is known about how stress response, neural processing of reward, and depression are related in very young children. |
2018-07-17 |
2023-08-13 |
Not clear |
| Michael S Gaffrey, Deanna M Barch, Ryan Bogdan, Katrina Farris, Steven E Petersen, Joan L Lub. Amygdala Reward Reactivity Mediates the Association Between Preschool Stress Response and Depression Severity. Biological psychiatry. vol 83. issue 2. 2018-07-17. PMID:29102026. |
the present study examined the concurrent associations between cortisol response following a stressor, functional brain activity to reward, and depression severity in children 4 to 6 years old. |
2018-07-17 |
2023-08-13 |
Not clear |
| Karolina Janacsek, Emőke Borbély-Ipkovich, Dezso Nemeth, Xénia Gond. How can the depressed mind extract and remember predictive relationships of the environment? Evidence from implicit probabilistic sequence learning. Progress in neuro-psychopharmacology & biological psychiatry. vol 81. 2018-06-27. PMID:28958916. |
these results cannot be explained by alterations in motivation, attention and reward processing but suggest more profound impairments of implicit learning and retention of predictive relationships among neutral stimuli in depression. |
2018-06-27 |
2023-08-13 |
Not clear |
| Marta Peciña, Magdalena Sikora, Erich T Avery, Joseph Heffernan, Susana Peciña, Brian J Mickey, Jon-Kar Zubiet. Striatal dopamine D2/3 receptor-mediated neurotransmission in major depression: Implications for anhedonia, anxiety and treatment response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 27. issue 10. 2018-05-30. PMID:28870407. |
dopamine (da) neurotransmission within the brain's reward circuit has been implicated in the pathophysiology of depression and in both, cognitive and pharmacological mechanisms of treatment response. |
2018-05-30 |
2023-08-13 |
Not clear |
| Wen-Hua Liu, Vincent Valton, Ling-Zhi Wang, Yu-Hua Zhu, Jonathan P Roise. Association between habenula dysfunction and motivational symptoms in unmedicated major depressive disorder. Social cognitive and affective neuroscience. vol 12. issue 9. 2018-05-24. PMID:28575424. |
the lateral habenula plays a central role in reward and punishment processing and has been suggested to drive the cardinal symptom of anhedonia in depression. |
2018-05-24 |
2023-08-13 |
human |
| Kerstin Brinkmann, Jessica Franze. Blunted cardiovascular reactivity during social reward anticipation in subclinical depression. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 119. 2018-05-10. PMID:28130127. |
the present study extends past research about reduced reward responsiveness in depression by assessing effort-related cardiovascular responses during anticipation of a social reward. |
2018-05-10 |
2023-08-13 |
human |
| Katherine R Luking, David Pagliaccio, Joan L Luby, Deanna M Barc. Reward Processing and Risk for Depression Across Development. Trends in cognitive sciences. vol 20. issue 6. 2018-04-12. PMID:27131776. |
reward processing and risk for depression across development. |
2018-04-12 |
2023-08-13 |
Not clear |
| Sayori Yashiro, Kenjiro Sek. Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain. Stress (Amsterdam, Netherlands). vol 20. issue 4. 2018-03-26. PMID:28554247. |
anhedonia is a core symptom of social defeat stress (sds)-induced depression associated with the reward system. |
2018-03-26 |
2023-08-13 |
mouse |
| Saki Minami, Hiroshi Satoyoshi, Soichiro Ide, Takeshi Inoue, Mitsuhiro Yoshioka, Masabumi Minam. Suppression of reward-induced dopamine release in the nucleus accumbens in animal models of depression: Differential responses to drug treatment. Neuroscience letters. vol 650. 2018-03-19. PMID:28432029. |
we investigated reward (30% sucrose intake)-induced da release in the nucleus accumbens (nac) and the effect of chronic treatment with the antidepressant escitalopram (5mg/kg, intraperitoneally twice daily for 3 weeks) in two animal models of depression. |
2018-03-19 |
2023-08-13 |
Not clear |
| Xi Zhu, Liat Helpman, Santiago Papini, Franklin Schneier, John C Markowitz, Page E Van Meter, Martin A Lindquist, Tor D Wager, Yuval Neri. Altered resting state functional connectivity of fear and reward circuitry in comorbid PTSD and major depression. Depression and anxiety. vol 34. issue 7. 2018-03-13. PMID:28030757. |
altered resting state functional connectivity of fear and reward circuitry in comorbid ptsd and major depression. |
2018-03-13 |
2023-08-13 |
Not clear |