| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Ji Wang, Sheng Bing Wu, Hong Liang Cheng, Chao Yang, Yun Chen, Jun Yan. [Effect of moxibustion on expression of RAGE and LRP-1 and neuronal ultrastructure of frontal cortex and hippocampus in vascular dementia rats]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 1. 2020-03-12. PMID:32144906. |
to explore the effect of moxibustion of acupoints of governor vessel on learning-memory ability and expression of the receptor for advanced glycation end products (rage), low density lipoprotein (ldl) receptor related protein-1 (lrp-1), β-amyloid precursor protein (app) and neuronal ultrastructure of the frontal cortex and hippocampus in vascular dementia (vd) rats, so as to investigate its underlying mechanisms in relieving vd. |
2020-03-12 |
2023-08-13 |
rat |
| Carmen Gasca-Salas, Daniel García-Lorenzo, David Garcia-Garcia, Pedro Clavero, José A Obeso, Stephane Lehericy, María C Rodríguez-Oro. Parkinson's disease with mild cognitive impairment: severe cortical thinning antedates dementia. Brain imaging and behavior. vol 13. issue 1. 2019-06-10. PMID:28710667. |
this study shows that aged and long-term pd patients with mci who convert to dementia in the short-mid term suffer a thinning of the cortex in several areas (frontal cortex, and middle temporal lobe and insula), even when their cognitive impairment was similar to that of pd-mci non-converters. |
2019-06-10 |
2023-08-13 |
Not clear |
| Gabriel Santpere, Paula Garcia-Esparcia, Pol Andres-Benito, Belen Lorente-Galdos, Arcadi Navarro, Isidro Ferre. Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies. Brain pathology (Zurich, Switzerland). vol 28. issue 3. 2019-01-24. PMID:28321951. |
the present study investigates global transcriptional changes in frontal cortex area 8 in incidental lewy body disease (ilbd), parkinson disease (pd) and dementia with lewy bodies (dlb). |
2019-01-24 |
2023-08-13 |
Not clear |
| Gabriel Santpere, Paula Garcia-Esparcia, Pol Andres-Benito, Belen Lorente-Galdos, Arcadi Navarro, Isidro Ferre. Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies. Brain pathology (Zurich, Switzerland). vol 28. issue 3. 2019-01-24. PMID:28321951. |
transcriptional network analysis in frontal cortex in lewy body diseases with focus on dementia with lewy bodies. |
2019-01-24 |
2023-08-13 |
Not clear |
| Paula Garcia-Esparcia, Anusha Koneti, M Cruz Rodríguez-Oroz, Belen Gago, José Antonio Del Rio, Isidro Ferre. Mitochondrial activity in the frontal cortex area 8 and angular gyrus in Parkinson's disease and Parkinson's disease with dementia. Brain pathology (Zurich, Switzerland). vol 28. issue 1. 2018-07-31. PMID:27984680. |
rt-qpcr of 18 nuclear mrnas encoding subunits of mitochondrial complexes and 12 mrnas encoding energy metabolism-related enzymes; western blotting of mitochondrial proteins; and analysis of enzymatic activities of complexes i, ii, ii, iv and v of the respiratory chain were assessed in frontal cortex area 8 and the angular gyrus of middle-aged individuals (ma), and those with incidental pd (ipd), long-lasting pd with parkinsonism without dementia (pd) and long-lasting pd with dementia (pdd). |
2018-07-31 |
2023-08-13 |
Not clear |
| Paula Garcia-Esparcia, Anusha Koneti, M Cruz Rodríguez-Oroz, Belen Gago, José Antonio Del Rio, Isidro Ferre. Mitochondrial activity in the frontal cortex area 8 and angular gyrus in Parkinson's disease and Parkinson's disease with dementia. Brain pathology (Zurich, Switzerland). vol 28. issue 1. 2018-07-31. PMID:27984680. |
mitochondrial activity in the frontal cortex area 8 and angular gyrus in parkinson's disease and parkinson's disease with dementia. |
2018-07-31 |
2023-08-13 |
Not clear |
| Raquel Marin, Noemí Fabelo, Virginia Martín, Paula Garcia-Esparcia, Isidre Ferrer, David Quinto-Alemany, Mario Día. Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases. Neurobiology of aging. vol 49. 2017-11-16. PMID:27768960. |
anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with lewy bodies disclose neurochemical traits partially shared by alzheimer's and parkinson's diseases. |
2017-11-16 |
2023-08-13 |
Not clear |
| Paul L Wood, Brooke L Barnette, Jeffrey A Kaye, Joseph F Quinn, Randall L Woltje. Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer's disease subjects. Acta neuropsychiatrica. vol 27. issue 5. 2016-05-12. PMID:25858158. |
we undertook a non-targeted lipidomics analysis of post-mortem cerebrospinal fluid (csf), frontal cortex grey matter, and subjacent white matter to define potential biomarkers that distinguish cognitively intact subjects from those with incipient or established dementia. |
2016-05-12 |
2023-08-13 |
human |
| Tomasz Brudek, Kristian Winge, Nadja Bredo Rasmussen, Justyna Maria Czarna Bahl, Julia Tanassi, Tina Klitmøller Agander, Thomas M Hyde, Bente Pakkenber. Altered α-synuclein, parkin, and synphilin isoform levels in multiple system atrophy brains. Journal of neurochemistry. vol 136. issue 1. 2016-04-25. PMID:26465922. |
previously, it has been shown that α-synuclein, parkin, and synphilin-1 display disease-specific transcription patterns in frontal cortex in pd, dementia with lewy bodies, and msa, and thus may mediate the development of α-synucleinopathies. |
2016-04-25 |
2023-08-13 |
Not clear |
| Andrew G Hoss, Adam Labadorf, Thomas G Beach, Jeanne C Latourelle, Richard H Myer. microRNA Profiles in Parkinson's Disease Prefrontal Cortex. Frontiers in aging neuroscience. vol 8. 2016-03-14. PMID:26973511. |
the goal of this study was to compare the microrna (mirna) profile of parkinson's disease (pd) frontal cortex with normal control brain, allowing for the identification of pd specific signatures as well as study the disease-related phenotypes of onset age and dementia. |
2016-03-14 |
2023-08-13 |
Not clear |
| Rebecca B Weinberg, Elliott J Mufson, Scott E Count. Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment. Frontiers in neuroscience. vol 9. 2015-11-23. PMID:26594146. |
given the ability of frontal cortex to respond to the onset of dementia by neuronal reorganization, these data suggest that mirna-mediated up-regulation of the sirt1 pathway represents a compensatory response to the onset of the disease. |
2015-11-23 |
2023-08-13 |
human |
| Taya Thomas, Scott Miners, Seth Lov. Post-mortem assessment of hypoperfusion of cerebral cortex in Alzheimer's disease and vascular dementia. Brain : a journal of neurology. vol 138. issue Pt 4. 2015-06-16. PMID:25688080. |
in frontal cortex the mag:plp1 ratio was significantly reduced in alzheimer's disease and even more so in vascular dementia. |
2015-06-16 |
2023-08-13 |
Not clear |
| Eva Borger, Abigail Herrmann, David A Mann, Tara Spires-Jones, Frank Gunn-Moor. The calcium-binding protein EFhd2 modulates synapse formation in vitro and is linked to human dementia. Journal of neuropathology and experimental neurology. vol 73. issue 12. 2015-01-26. PMID:25383639. |
here we report that efhd2 protein and mrna levels are reduced in human frontal cortex tissue affected by different types of dementia with and without tau pathology. |
2015-01-26 |
2023-08-13 |
mouse |
| Jennifer M Coughlin, Yuchuan Wang, Shuangchao Ma, Chen Yue, Pearl K Kim, Ashley V Adams, Heidi V Roosa, Kenneth L Gage, Marigo Stathis, Rana Rais, Camilo Rojas, Jennifer L McGlothan, Crystal C Watkins, Ned Sacktor, Tomas R Guilarte, Yun Zhou, Akira Sawa, Barbara S Slusher, Brian Caffo, Michael Kassiou, Christopher J Endres, Martin G Pompe. Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV. Journal of neurovirology. vol 20. issue 3. 2015-01-12. PMID:24567030. |
regional tspo abnormalities were evident within a sub-cohort of neuro-asymptomatic hiv subjects, and an increase in the vt ratio within frontal cortex was specifically linked to individuals affected with hiv-associated dementia. |
2015-01-12 |
2023-08-12 |
human |
| Li Zhou, Gulietta M Pupo, Priyanka Gupta, Bing Liu, Sieu L Tran, Raany Rahme, Bin Wang, Rejane Rua, Helen Rizos, Adam Carroll, Murray J Cairns, Nitin K Saksen. A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration. BMC genomics. vol 13. 2013-07-12. PMID:23190615. |
a parallel genome-wide mrna and microrna profiling of the frontal cortex of hiv patients with and without hiv-associated dementia shows the role of axon guidance and downstream pathways in hiv-mediated neurodegeneration. |
2013-07-12 |
2023-08-12 |
Not clear |
| Rhoda Au, Sudha Seshadri, Kristen Knox, Alexa Beiser, Jayandra J Himali, Howard J Cabral, Sanford Auerbach, Robert C Green, Philip A Wolf, Ann C McKe. The Framingham Brain Donation Program: neuropathology along the cognitive continuum. Current Alzheimer research. vol 9. issue 6. 2012-12-14. PMID:22471865. |
the second examined the correlation of regional alzheimer-type pathology to cognitive status at death among 34 persons who were over the age of 75 and without any significant vascular or alternative neurodegenerative pathology and found that neurofibrillary tangle counts distinguished between persons who were controls, had mild cognitive impairment, mild or moderate dementia; tangles in dorsolateral frontal cortex best distinguished mci and controls. |
2012-12-14 |
2023-08-12 |
human |
| Ching-Paio Tsai, Bing-Wen Soong, Pang-Hsien Tu, Kon-Ping Lin, Jong-Ling Fuh, Pei-Chien Tsai, Yi-Chun Lu, I-Hui Lee, Yi-Chung Le. A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan. Neurobiology of aging. vol 33. issue 9. 2012-11-29. PMID:22673113. |
needle biopsy in the left frontal cortex of 1 patient with fals-frontotemporal dementia revealed numerous cytoplasmic tar dna-binding protein 43 (tdp-43) inclusions and minimal neuritis, consistent with type b frontotemporal lobar degeneration with tdp-43 (ftld-tdp) pathology. |
2012-11-29 |
2023-08-12 |
Not clear |
| Raúl de la Fuente-Fernánde. Frontostriatal cognitive staging in Parkinson's disease. Parkinson's disease. vol 2012. 2012-08-23. PMID:22191070. |
executive dysfunction and mental fatigue (stage i), depression/anxiety (stage iia), apathy/pain (stage iib), and dementia (stage iii) reflect a sequential process of dopamine depletion occurring in different regions of the striatum (stages i and ii) and the frontal cortex (stage iii). |
2012-08-23 |
2023-08-12 |
human |
| Simone A van den Berge, Josta T Kevenaar, Jacqueline A Sluijs, Elly M Ho. Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis. Parkinson's disease. vol 2012. 2012-08-23. PMID:22577599. |
we have examined these proteins by immunohistochemistry in the frontal cortex and by western blot in csf of cases with pd, pd with dementia (pdd), dementia with lewy bodies (dlb) and nondemented controls. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tommy Saing, Malcolm Dick, Peter T Nelson, Ronald C Kim, David H Cribbs, Elizabeth Hea. Frontal cortex neuropathology in dementia pugilistica. Journal of neurotrauma. vol 29. issue 6. 2012-08-06. PMID:22017610. |
frontal cortex neuropathology in dementia pugilistica. |
2012-08-06 |
2023-08-12 |
Not clear |