| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew Siderowf, Michael J Pontecorvo, Holly A Shill, Mark A Mintun, Anupa Arora, Abhinay D Joshi, Ming Lu, Charles H Adler, Douglas Galasko, Carolyn Liebsack, Daniel M Skovronsky, Marwan N Sabbag. PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders. BMC neurology. vol 14. 2015-01-16. PMID:24716655. |
biomarkers based on the underlying pathology of alzheimer's disease (ad) and dementia with lewy bodies (dlb) have the potential to improve diagnosis and understanding of the substrate for cognitive impairment in these disorders. |
2015-01-16 |
2023-08-13 |
Not clear |
| Li Sun, Jie Cao, Feng Na Chu, Zan Wang, Yudan L. Dementia with Lewy bodies versus nonconvulsive status epilepticus in the diagnosis of a patient with cognitive dysfunction, complex visual hallucinations and periodic abnormal waves in EEG: a case report. BMC neurology. vol 14. 2015-01-16. PMID:24884409. |
the diagnosis of dementia with lewy bodies (dlb) is often challenging in elderly individuals, not only for its various clinical features, sometimes, but also for its rare changes of periodic synchronous discharges (psd) in electroencephalogram ( eeg). |
2015-01-16 |
2023-08-13 |
Not clear |
| Henrietta M Nielsen, Sara Hall, Yulia Surova, Katarina Nägga, Christer Nilsson, Elisabet Londos, Lennart Minthon, Oskar Hansson, Malin Wennströ. Low levels of soluble NG2 in cerebrospinal fluid from patients with dementia with Lewy bodies. Journal of Alzheimer's disease : JAD. vol 40. issue 2. 2015-01-15. PMID:24448788. |
to further investigate whether alterations in sng2 is specific to ad pathology, we measured levels of sng2 in csf from a patient cohort consisting of non-demented controls (n = 51), patients with parkinson's disease (pd) (n = 61), and patients with dementia with lewy bodies (dlb) (n = 37), two synucleinopathies whereof the latter disorder frequently coincides with amyloid-β pathology similar to ad. |
2015-01-15 |
2023-08-12 |
Not clear |
| Xiaomei Zhong, Haishan Shi, Zhiwei Shen, Le Hou, Xinni Luo, Xinru Chen, Sha Liu, Yuefeng Zhang, Dong Zheng, Yan Tan, Guimao Huang, Yaxiu Fang, Hui Zhang, Nan Mu, Jianping Chen, Renhua Wu, Yuping Nin. 1H-proton magnetic resonance spectroscopy differentiates dementia with Lewy bodies from Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 40. issue 4. 2015-01-06. PMID:24531156. |
fdg-pet and spect studies suggest that hypometabolism and hypoperfusion in occipital lobe and posterior cingulate gyrus (pcg) are prominent features of dementia with lewy bodies (dlb) and alzheimer's disease (ad), respectively. |
2015-01-06 |
2023-08-12 |
human |
| Xiaomei Zhong, Haishan Shi, Zhiwei Shen, Le Hou, Xinni Luo, Xinru Chen, Sha Liu, Yuefeng Zhang, Dong Zheng, Yan Tan, Guimao Huang, Yaxiu Fang, Hui Zhang, Nan Mu, Jianping Chen, Renhua Wu, Yuping Nin. 1H-proton magnetic resonance spectroscopy differentiates dementia with Lewy bodies from Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 40. issue 4. 2015-01-06. PMID:24531156. |
our study suggests that 1h-mrs investigation is valuable to detect the characteristic patterns of metabolite concentrations and is helpful in the diagnostic process and assessing dementia severity in dlb. |
2015-01-06 |
2023-08-12 |
human |
| Pierre-Olivier Fernagut, Benjamin Dehay, Aline Maillard, Erwan Bezard, Paul Perez, Anne Pavy-Le Traon, Olivier Rascol, Alexandra Foubert-Samier, François Tison, Wassilios G Meissne. Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies. Neurobiology of disease. vol 67. 2015-01-06. PMID:24727096. |
together with pd and dementia with lewy bodies (dlb), msa belongs to the synucleinopathies, a group of neurodegenerative disorders characterized by the abnormal accumulation of alpha-synuclein. |
2015-01-06 |
2023-08-13 |
Not clear |
| James O'Donovan, Rosie Watson, Sean J Colloby, Andrew M Blamire, John T O'Brie. Assessment of regional MR diffusion changes in dementia with Lewy bodies and Alzheimer's disease. International psychogeriatrics. vol 26. issue 4. 2015-01-05. PMID:24331205. |
dementia with lewy bodies (dlb) and alzheimer's disease (ad) are common forms of dementia, yet diagnosis is often difficult. |
2015-01-05 |
2023-08-12 |
Not clear |
| Jung Han Yoon, Ji Eun Lee, Seok Woo Yong, So Young Moon, Phil Hyu Le. The mild cognitive impairment stage of dementia with Lewy bodies and Parkinson disease: a comparison of cognitive profiles. Alzheimer disease and associated disorders. vol 28. issue 2. 2015-01-02. PMID:24126215. |
recent studies have demonstrated that structural and pathologic changes are more severe in patients with dementia with lewy bodies (dlb) than in those with parkinson disease with dementia (pdd). |
2015-01-02 |
2023-08-12 |
Not clear |
| Carlo Abbate, Pietro Davide Trimarchi, Silvia Inglese, Niccolò Viti, Alessandra Cantatore, Lisa De Agostini, Federico Pirri, Lorenza Marino, Renzo Bagarolo, Daniela Mar. Preclinical polymodal hallucinations for 13 years before dementia with Lewy bodies. Behavioural neurology. vol 2014. 2014-12-24. PMID:24868122. |
we describe a case of dementia with lewy bodies (dlb) that presented long-lasting preclinical complex polymodal hallucinations. |
2014-12-24 |
2023-08-13 |
Not clear |
| Georgios Tsivgoulis, Anastasios Bonakis, Matilda A Papathanasiou, Maria Chondrogianni, Sokratis G Papageorgiou, Konstantinos Voumvourakis, Leonidas Stefani. Magnetic resonance imaging reveals Creutzfeldt-Jakob disease in a patient with apparent dementia with Lewy bodies. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24680564. |
the differential diagnosis of dementia with lewy bodies (dlb) and sporadic creutzfeldt-jakob disease (cjd) may be challenging. |
2014-12-22 |
2023-08-12 |
Not clear |
| Georgios Tsivgoulis, Anastasios Bonakis, Matilda A Papathanasiou, Maria Chondrogianni, Sokratis G Papageorgiou, Konstantinos Voumvourakis, Leonidas Stefani. Magnetic resonance imaging reveals Creutzfeldt-Jakob disease in a patient with apparent dementia with Lewy bodies. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24680564. |
we describe a 79-year old patient recently diagnosed with dementia with lewy bodies (dlb) on the basis of subacute cognitive decline, visual hallucinations and parkinsonian features, who presented with increasing agitation. |
2014-12-22 |
2023-08-12 |
Not clear |
| Kelley C O'Donnell, Aaron Lulla, Mark C Stahl, Nickolas D Wheat, Jeff M Bronstein, Alvaro Sagast. Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity. Disease models & mechanisms. vol 7. issue 5. 2014-12-17. PMID:24626988. |
α-synuclein (asyn) expression is implicated in neurodegenerative processes, including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2014-12-17 |
2023-08-12 |
human |
| Tanis J Ferman, Glenn E Smith, Dennis W Dickson, Neill R Graff-Radford, Siong-Chi Lin, Zbigniew Wszolek, Jay A Van Gerpen, Ryan Uitti, David S Knopman, Ronald C Petersen, Joseph E Parisi, Michael H Silber, Bradley F Boev. Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer's disease using the Multiple Sleep Latency Test. Alzheimer's research & therapy. vol 6. issue 9. 2014-12-16. PMID:25512763. |
excessive daytime sleepiness is a commonly reported problem in dementia with lewy bodies (dlb). |
2014-12-16 |
2023-08-13 |
Not clear |
| Tanis J Ferman, Glenn E Smith, Dennis W Dickson, Neill R Graff-Radford, Siong-Chi Lin, Zbigniew Wszolek, Jay A Van Gerpen, Ryan Uitti, David S Knopman, Ronald C Petersen, Joseph E Parisi, Michael H Silber, Bradley F Boev. Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer's disease using the Multiple Sleep Latency Test. Alzheimer's research & therapy. vol 6. issue 9. 2014-12-16. PMID:25512763. |
we examined the relationship between nighttime sleep continuity and the propensity to fall asleep during the day in clinically probable dlb compared to alzheimer's disease (ad) dementia. |
2014-12-16 |
2023-08-13 |
Not clear |
| Jonathan Graff-Radford, Melissa E Murray, Val J Lowe, Bradley F Boeve, Tanis J Ferman, Scott A Przybelski, Timothy G Lesnick, Matthew L Senjem, Jeffrey L Gunter, Glenn E Smith, David S Knopman, Clifford R Jack, Dennis W Dickson, Ronald C Petersen, Kejal Kantarc. Dementia with Lewy bodies: basis of cingulate island sign. Neurology. vol 83. issue 9. 2014-12-11. PMID:25056580. |
to investigate clinical, imaging, and pathologic associations of the cingulate island sign (cis) in dementia with lewy bodies (dlb). |
2014-12-11 |
2023-08-13 |
Not clear |
| Koji Kasanuki, Eizo Iseki, Daizo Kondo, Hiroshige Fujishiro, Michiko Minegishi, Kiyoshi Sato, Omi Katsuse, Hiroaki Hino, Kenji Kosaka, Heii Ara. Neuropathological investigation of hypocretin expression in brains of dementia with Lewy bodies. Neuroscience letters. vol 569. 2014-12-09. PMID:24704327. |
in the present study, we quantitatively examined hcrt immunoreactivity and α-synuclein and tau pathologies in the lht and locus coeruleus (lc) in dementia with lewy bodies (dlb) (n=15), alzheimer's disease (ad) (n=14), and controls (n=7). |
2014-12-09 |
2023-08-13 |
Not clear |
| Dominique Bétemps, Jérémy Verchère, Sébastien Brot, Eric Morignat, Luc Bousset, Damien Gaillard, Latifa Lakhdar, Ronald Melki, Thierry Baro. Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA. Acta neuropathologica communications. vol 2. 2014-12-08. PMID:24624994. |
in the case of synucleinopathies such as parkinson's disease (pd) or dementia with lewy bodies (dlb), the intraneuronal deposition of aggregated alpha-synuclein (αs) is a major characteristic of the disease, but the molecular basis distinguishing the disease-associated protein (αsd) from its normal counterpart remains poorly understood. |
2014-12-08 |
2023-08-12 |
mouse |
| Cristian A Lasagna-Reeves, Urmi Sengupta, Diana Castillo-Carranza, Julia E Gerson, Marcos Guerrero-Munoz, Juan C Troncoso, George R Jackson, Rakez Kaye. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta neuropathologica communications. vol 2. 2014-12-08. PMID:24887264. |
the present study examined the similarities of tau apfs with other tau amyloid species and showed for the first time the presence of tau apfs in brain tissue from patients with progressive supranuclear palsy (psp) and dementia with lewy bodies (dlb), as well as in the p301l mouse model, which overexpresses mutated tau. |
2014-12-08 |
2023-08-13 |
mouse |
| Paul C Donaghy, Ian G McKeit. The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis. Alzheimer's research & therapy. vol 6. issue 4. 2014-12-08. PMID:25484925. |
dementia with lewy bodies (dlb) is the second most common type of degenerative dementia following alzheimer's disease (ad). |
2014-12-08 |
2023-08-13 |
Not clear |
| Michael R Misch, Sara Mitchell, Philip L Francis, Kayla Sherborn, Katayoun Meradje, Alicia A McNeely, Kie Honjo, Jiali Zhao, Christopher Jm Scott, Curtis B Caldwell, Lisa Ehrlich, Prathiba Shammi, Bradley J MacIntosh, Juan M Bilbao, Anthony E Lang, Sandra E Black, Mario Maselli. Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography. Alzheimer's research & therapy. vol 6. issue 9. 2014-12-08. PMID:25484929. |
dementia with lewy bodies (dlb) and corticobasal syndrome (cbs) are atypical parkinsonian disorders with fronto-subcortical and posterior cognitive dysfunction as common features. |
2014-12-08 |
2023-08-13 |
Not clear |