| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rina Bandopadhya. Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains. Journal of visualized experiments : JoVE. issue 107. 2016-11-09. PMID:26780369. |
abnormally aggregated α-syn is a neuropathological feature of parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2016-11-09 |
2023-08-13 |
human |
| Mariya Petrova, Radka Pavlova, Yavor Zhelev, Shima Mehrabian, Margarita Raycheva, Latchezar Trayko. Investigation of neuropsychological characteristics of very mild and mild dementia with Lewy bodies. Journal of clinical and experimental neuropsychology. vol 38. issue 3. 2016-11-08. PMID:26678542. |
the study aimed to compare the profile of very mild and mild dementia with lewy bodies (dlb) patients with disease duration up to 5 years in order to find markers for faster progression in this early stage. |
2016-11-08 |
2023-08-13 |
Not clear |
| Jon B Toledo, Pallavi Gopal, Kevin Raible, David J Irwin, Johannes Brettschneider, Samantha Sedor, Kayla Waits, Susana Boluda, Murray Grossman, Vivianna M Van Deerlin, Edward B Lee, Steven E Arnold, John E Duda, Howard Hurtig, Virginia M-Y Lee, Charles H Adler, Thomas G Beach, John Q Trojanowsk. Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta neuropathologica. vol 131. issue 3. 2016-11-08. PMID:26721587. |
we investigated the distribution patterns of lewy body-related pathology (lrp) and the effect of coincident alzheimer disease (ad) pathology using a data-driven clustering approach that identified groups with different lrp pathology distributions without any diagnostic or researcher's input in two cohorts including: parkinson disease patients without (pd, n = 141) and with ad (pd-ad, n = 80), dementia with lewy bodies subjects without ad (dlb, n = 13) and demented subjects with ad and lrp pathology (dem-ad-lb, n = 308). |
2016-11-08 |
2023-08-13 |
human |
| Ulf Dettmer, Dennis Selkoe, Tim Bartel. New insights into cellular α-synuclein homeostasis in health and disease. Current opinion in neurobiology. vol 36. 2016-11-01. PMID:26282834. |
misfolding and aggregation of this normally soluble, 140-residue polypeptide underlies a group of neurodegenerative disorders called synucleinopathies, including parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2016-11-01 |
2023-08-13 |
Not clear |
| Alison Killen, Darren Flynn, Aoife De Brún, Nicola O'Brien, John O'Brien, Alan J Thomas, Ian McKeith, John-Paul Taylo. Support and information needs following a diagnosis of dementia with Lewy bodies. International psychogeriatrics. vol 28. issue 3. 2016-10-31. PMID:26328546. |
there is a lack of knowledge regarding the information and support needs of people with dementia with lewy bodies (dlb) and their families around the time of diagnosis. |
2016-10-31 |
2023-08-13 |
Not clear |
| Sho Takahashi, Katsuyoshi Mizukami, Tetsuaki Arai, Ryoko Ogawa, Norihiro Kikuchi, Satoshi Hattori, David Darby, Takashi Asad. Ventilatory Response to Hypercapnia Predicts Dementia with Lewy Bodies in Late-Onset Major Depressive Disorder. Journal of Alzheimer's disease : JAD. vol 50. issue 3. 2016-10-31. PMID:26757183. |
depression is particularly common in dementia with lewy bodies (dlb), and occasionally occurs before the onset of extrapyramidal symptoms. |
2016-10-31 |
2023-08-13 |
Not clear |
| b' Hana P\\xc5\\x99ikrylov\\xc3\\xa1 Vranov\\xc3\\xa1, Eva H\\xc3\\xa9nykov\\xc3\\xa1, Jan Mare\\xc5\\xa1, Michaela Kaiserov\\xc3\\xa1, Kate\\xc5\\x99ina Men\\xc5\\xa1\\xc3\\xadkov\\xc3\\xa1, Miroslav Va\\xc5\\xa1t\\xc3\\xadk, Petr Hlu\\xc5\\xa1t\\xc3\\xadk, Jana Zapletalov\\xc3\\xa1, Miroslav Strnad, David Stejskal, Petr Ka\\xc5\\x88ovsk\\xc3\\xb. Clusterin CSF levels in differential diagnosis of neurodegenerative disorders. Journal of the neurological sciences. vol 361. 2016-10-20. PMID:26810527.' |
in the brain, post-mortem analysis has found increased clusterin associated with the pathology of many other neurodegenerative diseases (nd) such as parkinson's disease (pd), dementia with lewy bodies (dlb), alzheimer's disease (ad) and multiple system atrophy (msa). |
2016-10-20 |
2023-08-13 |
Not clear |
| M J Keogh, M Kurzawa-Akanbi, H Griffin, K Douroudis, K L Ayers, R I Hussein, G Hudson, A Pyle, H J Cordell, J Attems, I G McKeith, J T O'Brien, D J Burn, C M Morris, A J Thomas, P F Chinner. Exome sequencing in dementia with Lewy bodies. Translational psychiatry. vol 6. 2016-10-17. PMID:26836416. |
dementia with lewy bodies (dlb) is the second most common form of degenerative dementia. |
2016-10-17 |
2023-08-13 |
Not clear |
| Elijah Mak, Li Su, Guy B Williams, Rosie Watson, Michael Firbank, Andrew Blamire, John O'Brie. Differential Atrophy of Hippocampal Subfields: A Comparative Study of Dementia with Lewy Bodies and Alzheimer Disease. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 24. issue 2. 2016-10-13. PMID:26324541. |
dementia with lewy bodies (dlb) is characterized by relative preservation of the medial temporal lobe compared with alzheimer disease (ad). |
2016-10-13 |
2023-08-13 |
human |
| Kathleen Van Dyk, Stephanie Towns, Oksana Tatarina, Philip Yeung, Jhedy Dorrejo, Laura B Zahodne, Yaakov Ster. Assessing Fluctuating Cognition in Dementia Diagnosis: Interrater Reliability of the Clinician Assessment of Fluctuation. American journal of Alzheimer's disease and other dementias. vol 31. issue 2. 2016-10-10. PMID:26340964. |
fluctuating cognition (fc) is a core feature of dementia with lewy bodies (dlb) but is challenging to assess. |
2016-10-10 |
2023-08-13 |
Not clear |
| Holly James Westervelt, Jared M Bruce, Melanie A Faus. Distinguishing Alzheimer's disease and dementia with Lewy bodies using cognitive and olfactory measures. Neuropsychology. vol 30. issue 3. 2016-10-07. PMID:26280301. |
given poor sensitivity of the diagnostic criteria in identifying dementia with lewy bodies (dlb), the use of cognitive and olfactory measures to distinguish alzheimer's disease (ad) from dlb was assessed. |
2016-10-07 |
2023-08-13 |
Not clear |
| Julie Vallortigara, David Whitfield, William Quelch, Amani Alghamdi, David Howlett, Tibor Hortobágyi, Mary Johnson, Johannes Attems, John T O'Brien, Alan Thomas, Clive G Ballard, Dag Aarsland, Paul T Franci. Decreased Levels of VAMP2 and Monomeric Alpha-Synuclein Correlate with Duration of Dementia. Journal of Alzheimer's disease : JAD. vol 50. issue 1. 2016-10-07. PMID:26639969. |
alpha-synuclein (α-syn) aggregations are the key pathological hallmark of dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd), but are also frequently present in alzheimer's disease (ad). |
2016-10-07 |
2023-08-13 |
Not clear |
| Kazumi Ota, Hiroshige Fujishiro, Koji Kasanuki, Daizo Kondo, Yuhei Chiba, Norio Murayama, Heii Arai, Kiyoshi Sato, Eizo Isek. Prediction of later clinical course by a specific glucose metabolic pattern in non-demented patients with probable REM sleep behavior disorder admitted to a memory clinic: A case study. Psychiatry research. Neuroimaging. vol 248. 2016-10-07. PMID:26754469. |
during the follow-up period (mean±sd of 46.7±6.4 months), all 11 patients exhibited cognitive decline: four (group a) exhibited core clinical features of dementia with lewy bodies (dlb), along with severe cognitive decline, and were subsequently diagnosed as having probable dlb; four (group b) did not exhibit core clinical features of dlb; and the remaining three (group c) were diagnosed as having parkinson's disease with dementia (pdd). |
2016-10-07 |
2023-08-13 |
Not clear |
| Alexandra Economou, Christopher Routsis, Sokratis G Papageorgio. Episodic Memory in Alzheimer Disease, Frontotemporal Dementia, and Dementia With Lewy Bodies/Parkinson Disease Dementia: Disentangling Retrieval From Consolidation. Alzheimer disease and associated disorders. vol 30. issue 1. 2016-10-05. PMID:25730300. |
differences in episodic memory performance in patients with alzheimer disease (ad), frontotemporal dementia (ftd), dementia with lewy bodies (dlb)/parkinson disease with dementia (pdd) are inconsistent and task dependent. |
2016-10-05 |
2023-08-13 |
Not clear |
| Kelly M Landy, David P Salmon, J Vincent Filoteo, William C Heindel, Douglas Galasko, Joanne M Hamilto. Visual search in Dementia with Lewy Bodies and Alzheimer's disease. Cortex; a journal devoted to the study of the nervous system and behavior. vol 73. 2016-09-29. PMID:26476402. |
visual search is an aspect of visual cognition that may be more impaired in dementia with lewy bodies (dlb) than alzheimer's disease (ad). |
2016-09-29 |
2023-08-13 |
human |
| Kelly M Landy, David P Salmon, J Vincent Filoteo, William C Heindel, Douglas Galasko, Joanne M Hamilto. Visual search in Dementia with Lewy Bodies and Alzheimer's disease. Cortex; a journal devoted to the study of the nervous system and behavior. vol 73. 2016-09-29. PMID:26476402. |
to assess this possibility, the present study compared patients with dlb (n = 17), ad (n = 30), or parkinson's disease with dementia (pdd; n = 10) to non-demented patients with pd (n = 18) and normal control (nc) participants (n = 13) on single-feature and feature-conjunction visual search tasks. |
2016-09-29 |
2023-08-13 |
human |
| R A Armstron. Oculo-Visual Dysfunction in Parkinson's Disease. Journal of Parkinson's disease. vol 5. issue 4. 2016-09-29. PMID:26599301. |
pd, progressive supranuclear palsy (psp), dementia with lewy bodies (dlb), multiple system atrophy (msa), and corticobasal degeneration (cbd)? |
2016-09-29 |
2023-08-13 |
Not clear |
| Manabu Ikeda, Etsuro Mori, Eizo Iseki, Sadao Katayama, Yasuto Higashi, Mamoru Hashimoto, Hideaki Miyagishi, Masaki Nakagawa, Kenji Kosak. Adequacy of Using Consensus Guidelines for Diagnosis of Dementia with Lewy Bodies in Clinical Trials for Drug Development. Dementia and geriatric cognitive disorders. vol 41. issue 1-2. 2016-09-27. PMID:26623649. |
to evaluate the adequacy of using the consensus diagnostic criteria for dementia with lewy bodies (dlb) to recruit patients with homogeneous characteristics in future clinical trials, where multiple departments of multinational centres are expected to participate with a long enrolment period, and additionally, to contribute to the possible future criteria revision. |
2016-09-27 |
2023-08-13 |
Not clear |
| Francesco Brigo, Giulia Turri, Michele Tinazz. 123I-FP-CIT SPECT in the differential diagnosis between dementia with Lewy bodies and other dementias. Journal of the neurological sciences. vol 359. issue 1-2. 2016-09-27. PMID:26671107. |
to systematically review the utility of dopamine system imaging using 123i-fp-cit spect in the differential diagnosis between dementia with lewy bodies (dlb) and other dementia syndromes. |
2016-09-27 |
2023-08-13 |
Not clear |
| Soichiro Shimizu, Kentaro Hirao, Hidekazu Kanetaka, Nayuta Namioka, Hirokuni Hatanaka, Daisuke Hirose, Raita Fukasawa, Takahiko Umahara, Hirohumi Sakurai, Haruo Hany. Utility of the combination of DAT SPECT and MIBG myocardial scintigraphy in differentiating dementia with Lewy bodies from Alzheimer's disease. European journal of nuclear medicine and molecular imaging. vol 43. issue 1. 2016-09-26. PMID:26233438. |
(123)i-2β-carbomethoxy-3β-(4-iodophenyl)-n-(3-fluoropropyl) nortropane ((123)i-fp-cit) dopamine transporter single photon emission computed tomography (dat spect) and (123)i-metaiodobenzylguanidine (mibg) myocardial scintigraphy can be used to assist in the diagnosis of patients with dementia with lewy bodies (dlb). |
2016-09-26 |
2023-08-13 |
Not clear |