| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jack C de la Torr. Are Major Dementias Triggered by Poor Blood Flow to the Brain? Theoretical Considerations. Journal of Alzheimer's disease : JAD. vol 57. issue 2. 2018-02-26. PMID:28211814. |
this commentary proposes that dementia with lewy bodies (dlb), frontotemporal dementia (ftd), and creutzfeldt-jakob disease (cjd) may also develop from chronic brain hypoperfusion following a similar but not identical neurometabolic breakdown as ad. |
2018-02-26 |
2023-08-13 |
Not clear |
| Amani Alghamdi, Julie Vallortigara, David R Howlett, Martin Broadstock, Tibor Hortobágyi, Clive Ballard, Alan J Thomas, John T O'Brien, Dag Aarsland, Johannes Attems, Paul T Francis, David R Whitfiel. Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia. Journal of Alzheimer's disease : JAD. vol 57. issue 2. 2018-02-26. PMID:28269775. |
the middle frontal (brodmann, ba9), inferior parietal (ba40), and anterior cingulate (ba24) gyrus' cortex were selected as regions of interest from parkinson's disease dementia (pdd, n = 31), dementia with lewy bodies (dlb, n = 44), alzheimer's disease (ad, n = 16), and control (n = 24) brains. |
2018-02-26 |
2023-08-13 |
Not clear |
| Amani Alghamdi, Julie Vallortigara, David R Howlett, Martin Broadstock, Tibor Hortobágyi, Clive Ballard, Alan J Thomas, John T O'Brien, Dag Aarsland, Johannes Attems, Paul T Francis, David R Whitfiel. Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia. Journal of Alzheimer's disease : JAD. vol 57. issue 2. 2018-02-26. PMID:28269775. |
these findings highlight the involvement of the ups in lewy body dementia and indicate that targeting the ups may have the potential to slow down or reduce the progression of cognitive impairment in dlb and pdd. |
2018-02-26 |
2023-08-13 |
Not clear |
| John H T Power, Olivia L Barnes, Fariba Chegin. Lewy Bodies and the Mechanisms of Neuronal Cell Death in Parkinson's Disease and Dementia with Lewy Bodies. Brain pathology (Zurich, Switzerland). vol 27. issue 1. 2018-02-23. PMID:26667592. |
neuronal loss in specific brain regions and neurons with intracellular inclusions termed lewy bodies are the pathologic hallmark in both parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2018-02-23 |
2023-08-13 |
human |
| Daniel Erskine, Alan J Thomas, John-Paul Taylor, Michael A Savage, Johannes Attems, Ian G McKeith, Christopher M Morris, Ahmad A Khundaka. Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 25. issue 6. 2018-02-23. PMID:28190674. |
patients with dementia with lewy bodies (dlb) often experience visual hallucinations, which are related to decreased quality of life for patients and increased caregiver distress. |
2018-02-23 |
2023-08-13 |
Not clear |
| Janet L Mace, Richard J Porter, John C Dalrymple-Alford, Chris Collins, Tim J Anderso. Acute tryptophan depletion and Lewy body dementias. International psychogeriatrics. vol 28. issue 9. 2018-02-22. PMID:26987723. |
based on the severe cholinergic loss evident in dementia with lewy bodies (dlb) and parkinson's disease and dementia (pdd), we predicted that a reduction of global cognitive status during atd would be greater in these conditions than in ad. |
2018-02-22 |
2023-08-13 |
Not clear |
| Ellen Svendsboe, Toril Terum, Ingelin Testad, Dag Aarsland, Ingun Ulstein, Anne Corbett, Arvid Rongv. Caregiver burden in family carers of people with dementia with Lewy bodies and Alzheimer's disease. International journal of geriatric psychiatry. vol 31. issue 9. 2018-02-21. PMID:26765199. |
to characterise the differences in caregiver distress between carers of people diagnosed with dementia with lewy bodies (dlb) and people with alzheimer's disease (ad), with a view to differentiating and improving support for caregivers. |
2018-02-21 |
2023-08-13 |
Not clear |
| Hui Jin Ryu, Minyoung Kim, Yeonsil Moon, Yeji Choi, Jee-Young Han, James E Galvin, Seol-Heui Ha. Validation of the Korean Version of the Lewy Body Composite Risk Score (K-LBCRS). Journal of Alzheimer's disease : JAD. vol 55. issue 4. 2018-02-20. PMID:27834773. |
cdr-sum of boxes, mini-mental state examination, and standardized scales related to cognition, mood, behavior, and motor function were administered to a total of 107 subjects, including 30 dementia with lewy bodies (dlb), 54 alzheimer's disease (ad), and 23 cognitively normal elderly people and their collateral informants. |
2018-02-20 |
2023-08-13 |
human |
| Stephanie T Hirschbichler, Roberto Erro, Christos Ganos, Maria Stamelou, Amit Batla, Bettina Balint, Kailash P Bhati. "Atypical" atypical parkinsonism: Critical appraisal of a cohort. Parkinsonism & related disorders. vol 37. 2018-02-20. PMID:28236526. |
atypical parkinsonian conditions such as multiple system atrophy (msa), progressive supranuclear palsy (psp), corticobasal syndrome (cbs) and dementia with lewy bodies (dlb) comprise 10-15% of parkinsonian syndromes. |
2018-02-20 |
2023-08-13 |
Not clear |
| Kazuki Tabata, Yasuaki Saijo, Fumiyoshi Morikawa, Juichiro Naoe, Eiji Yoshioka, Yasuyuki Kawanishi, Yoshihiko Nakagi, Takahiko Yoshid. Association of premorbid personality with behavioral and psychological symptoms in dementia with Lewy bodies: Comparison with Alzheimer's disease patients. Psychiatry and clinical neurosciences. vol 71. issue 6. 2018-02-19. PMID:28177178. |
the aim of this study was to elucidate the relation between premorbid personality traits and behavioral and psychological symptoms in dementia (bpsd) in dementia with lewy bodies (dlb) and alzheimer's disease (ad) patients. |
2018-02-19 |
2023-08-13 |
Not clear |
| Jennifer Y Y Szeto, Glenda M Halliday, Sharon L Naismith, Simon J G Lewi. Exploring the Phenotype in Mild Cognitive Impairment to Aid the Prediction of Those at Risk of Transitioning to Parkinson Disease and Dementia With Lewy Bodies. Journal of geriatric psychiatry and neurology. vol 30. issue 4. 2018-02-13. PMID:28639878. |
to date, only limited research has concurrently investigated the presence of rapid eye movement sleep behavior disorder (rbd) and other features associated with parkinson disease (pd) and dementia with lewy bodies (dlb) in people presenting with mild cognitive impairment (mci). |
2018-02-13 |
2023-08-13 |
Not clear |
| Daniel Erskine, John Paul Taylor, Michael J Firbank, Lina Patterson, Marco Onofrj, John T O'Brien, Ian G McKeith, Johannes Attems, Alan J Thomas, Chris M Morris, Ahmad Adam Khundaka. Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies. Neuropathology and applied neurobiology. vol 42. issue 4. 2018-02-12. PMID:25967384. |
complex visual hallucinations occur in 70% of dementia with lewy bodies (dlb) cases and significantly affect patient well-being. |
2018-02-12 |
2023-08-13 |
Not clear |
| Greg J Elder, Sean J Colloby, Debra J Lett, John T O'Brien, Kirstie N Anderson, David J Burn, Ian G McKeith, John-Paul Taylo. Depressive symptoms are associated with daytime sleepiness and subjective sleep quality in dementia with Lewy bodies. International journal of geriatric psychiatry. vol 31. issue 7. 2018-02-12. PMID:26560190. |
sleep problems and depression are common symptoms in dementia with lewy bodies (dlb), where patients typically experience subjectively poor sleep quality, fatigue and excessive daytime sleepiness. |
2018-02-12 |
2023-08-13 |
Not clear |
| Shuling Liu, Yi Jin, Zhihong Shi, Ya Ruth Huo, Yalin Guan, Mengyuan Liu, Shuai Liu, Yong J. The effects of behavioral and psychological symptoms on caregiver burden in frontotemporal dementia, Lewy body dementia, and Alzheimer's disease: clinical experience in China. Aging & mental health. vol 21. issue 6. 2018-02-09. PMID:26882509. |
caregivers of individuals with neurodegenerative diseases, including frontotemporal dementia (ftd), lewy body dementia (dlb), and alzheimer's disease (ad), experience high levels of psychological and physical stress, likely due to behavioral and psychological symptoms of dementia (bpsd). |
2018-02-09 |
2023-08-13 |
Not clear |
| L Tagliafierro, O Chiba-Fale. Up-regulation of SNCA gene expression: implications to synucleinopathies. Neurogenetics. vol 17. issue 3. 2018-02-09. PMID:26948950. |
however, the precise variants within snca gene that contribute to the sporadic forms of parkinson's disease (pd), dementia with lewy bodies (dlb), multiple system atrophy (msa), and other synucleinopathies and their molecular mechanisms of action remain elusive. |
2018-02-09 |
2023-08-13 |
Not clear |
| Guerry M Peavy, Steven D Edland, Belinda M Toole, Lawrence A Hansen, Douglas R Galasko, Ann M May. Phenotypic differences based on staging of Alzheimer's neuropathology in autopsy-confirmed dementia with Lewy bodies. Parkinsonism & related disorders. vol 31. 2018-02-06. PMID:27475955. |
the goal was to compare subgroups of dementia with lewy bodies (dlb) using neuropathological measures to differentiate 'pure' lewy body (lb) dementia from 'mixed' dlb [co-occurring lb and alzheimer's disease (ad) pathology] to facilitate diagnostic decision-making and future development of interventions based on predicted type(s) of neuropathology. |
2018-02-06 |
2023-08-13 |
Not clear |
| Michael G Heckman, Alexandra I Soto-Ortolaza, Monica Y Sanchez Contreras, Melissa E Murray, Otto Pedraza, Nancy N Diehl, Ronald Walton, Catherine Labbé, Oswaldo Lorenzo-Betancor, Ryan J Uitti, Jay van Gerpen, Nilüfer Ertekin-Taner, Glenn E Smith, Kejal Kantarci, Rodolfo Savica, David T Jones, Jonathan Graff-Radford, David S Knopman, Val J Lowe, Clifford R Jack, Ronald C Petersen, Joseph E Parisi, Rosa Rademakers, Zbigniew K Wszolek, Neill R Graff-Radford, Tanis J Ferman, Dennis W Dickson, Bradley F Boeve, Owen A Ros. LRRK2 variation and dementia with Lewy bodies. Parkinsonism & related disorders. vol 31. 2018-02-06. PMID:27521182. |
however, little is known about the role of lrrk2 in dementia with lewy bodies (dlb). |
2018-02-06 |
2023-08-13 |
Not clear |
| Wei Yue, Xiao-Dan Wang, Zhihong Shi, Yajing Wang, Shuai Liu, Shuling Liu, Ying Zhang, Yajing Zhang, Hui Lu, Wenhua Su, Yong J. The prevalence of dementia with Lewy bodies in a rural area of China. Parkinsonism & related disorders. vol 29. 2018-02-05. PMID:27264344. |
data on the prevalence of dementia with lewy bodies (dlb) in china are limited. |
2018-02-05 |
2023-08-13 |
Not clear |
| Wiebke Schrempf, Istvan Katona, Imis Dogan, Verena V Felbert, Miriam Wienecke, Julia Heller, Andrea Maier, Andreas Hermann, Katharina Linse, Moritz D Brandt, Heinz Reichmann, Jörg B Schulz, Johannes Schiefer, Wolfgang H Oertel, Alexander Storch, Joachim Weis, Kathrin Reet. Reduced intraepidermal nerve fiber density in patients with REM sleep behavior disorder. Parkinsonism & related disorders. vol 29. 2018-02-05. PMID:27318706. |
idiopathic rapid eye movement (rem) sleep behavior disorder (irbd) has been increasingly acknowledged to be an initial specific manifestation of alpha-synucleinopathies such as parkinson's disease (pd), multiple system atrophy (msa) and dementia with lewy bodies (dlb). |
2018-02-05 |
2023-08-13 |
Not clear |
| Luis R Peraza, Sean J Colloby, Liam Deboys, John T O'Brien, Marcus Kaiser, John-Paul Taylo. Regional functional synchronizations in dementia with Lewy bodies and Alzheimer's disease. International psychogeriatrics. vol 28. issue 7. 2018-01-30. PMID:26976496. |
dementia with lewy bodies (dlb) is a common cause of dementia in the elderly population after alzheimer's disease (ad), and at early stages differential diagnosis between dlb and ad might be difficult due to their symptomatic overlap, e.g. |
2018-01-30 |
2023-08-13 |
Not clear |