| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ann M Mayo, Guerry M Peav. Associations among Braak stage, Parkinsonian gait, cognition, and functional status in autopsy-confirmed dementia with Lewy bodies. International journal of geriatric psychiatry. vol 34. issue 5. 2019-12-20. PMID:30729576. |
compromised functional abilities in older adults with dementia with lewy bodies (dlb) represent a significant burden to families and frequently lead to institutionalization. |
2019-12-20 |
2023-08-13 |
Not clear |
| Elijah Mak, Paul C Donaghy, Elizabeth McKiernan, Michael J Firbank, Jim Lloyd, George S Petrides, Alan J Thomas, John T O'Brie. Beta amyloid deposition maps onto hippocampal and subiculum atrophy in dementia with Lewy bodies. Neurobiology of aging. vol 73. 2019-12-19. PMID:30339962. |
although dementia with lewy bodies (dlb) is a synucleinopathy, it is frequently accompanied by beta amyloid (aβ) accumulation. |
2019-12-19 |
2023-08-13 |
human |
| Miwako Kawamura, Shigeto Sato, Gen Matsumoto, Takahiro Fukuda, Kahori Shiba-Fukushima, Sachiko Noda, Masashi Takanashi, Nozomu Mori, Nobutaka Hattor. Loss of nuclear REST/NRSF in aged-dopaminergic neurons in Parkinson's disease patients. Neuroscience letters. vol 699. 2019-12-17. PMID:30684677. |
on the other hand, rest is partially sequestrated in lewy bodies and is mostly absent from the nucleus of neurons in brains with pd and dementia with lewy bodies (dlb). |
2019-12-17 |
2023-08-13 |
mouse |
| Lucilla Parnetti, Silvia Paciotti, Lucia Farotti, Giovanni Bellomo, Federica Nicoletta Sepe, Paolo Euseb. Parkinson's and Lewy body dementia CSF biomarkers. Clinica chimica acta; international journal of clinical chemistry. vol 495. 2019-12-11. PMID:31051162. |
the clinical diagnosis of parkinson's disease (pd) and dementia with lewy bodies (dlb) is challenging due to highly variable clinical presentation and clinical and pathological overlap with other neurodegenerative diseases. |
2019-12-11 |
2023-08-13 |
Not clear |
| V Donadio, A Incensi, O El-Agnaf, G Rizzo, N Vaikath, F Del Sorbo, C Scaglione, S Capellari, A Elia, M Stanzani Maserati, R Pantieri, R Liguor. Skin α-synuclein deposits differ in clinical variants of synucleinopathy: an in vivo study. Scientific reports. vol 8. issue 1. 2019-12-09. PMID:30250046. |
we studied multiple skin nerve α-syn deposits in 44 patients with synucleinopathy: 15 idiopathic parkinson's disease (ipd), 12 dementia with lewy bodies (dlb), 5 pure autonomic failure (paf) and 12 multiple system atrophy (msa). |
2019-12-09 |
2023-08-13 |
human |
| Claudio Babiloni, Claudio Del Percio, Maria Teresa Pascarelli, Roberta Lizio, Giuseppe Noce, Susanna Lopez, Marco Rizzo, Raffaele Ferri, Andrea Soricelli, Flavio Nobili, Dario Arnaldi, Francesco Famà, Francesco Orzi, Carla Buttinelli, Franco Giubilei, Marco Salvetti, Virginia Cipollini, Raffaella Franciotti, Marco Onofrj, Paola Stirpe, Peter Fuhr, Ute Gschwandtner, Gerhard Ransmayr, Dag Aarsland, Lucilla Parnetti, Lucia Farotti, Moira Marizzoni, Fabrizia D'Antonio, Carlo De Lena, Bahar Güntekin, Lutfu Hanoğlu, Görsev Yener, Derya Durusu Emek-Savaş, Antonio Ivano Triggiani, John Paul Taylor, Ian McKeith, Fabrizio Stocchi, Laura Vacca, Harald Hampel, Giovanni B Frisoni, Maria Francesca De Pandis, Laura Bonann. Abnormalities of functional cortical source connectivity of resting-state electroencephalographic alpha rhythms are similar in patients with mild cognitive impairment due to Alzheimer's and Lewy body diseases. Neurobiology of aging. vol 77. 2019-12-06. PMID:30797169. |
previous evidence has shown different resting-state eyes-closed electroencephalographic delta (<4 hz) and alpha (8-10.5 hz) source connectivity in subjects with dementia due to alzheimer's (add) and lewy body (dlb) diseases. |
2019-12-06 |
2023-08-13 |
human |
| Claudio Babiloni, Claudio Del Percio, Maria Teresa Pascarelli, Roberta Lizio, Giuseppe Noce, Susanna Lopez, Marco Rizzo, Raffaele Ferri, Andrea Soricelli, Flavio Nobili, Dario Arnaldi, Francesco Famà, Francesco Orzi, Carla Buttinelli, Franco Giubilei, Marco Salvetti, Virginia Cipollini, Raffaella Franciotti, Marco Onofrj, Paola Stirpe, Peter Fuhr, Ute Gschwandtner, Gerhard Ransmayr, Dag Aarsland, Lucilla Parnetti, Lucia Farotti, Moira Marizzoni, Fabrizia D'Antonio, Carlo De Lena, Bahar Güntekin, Lutfu Hanoğlu, Görsev Yener, Derya Durusu Emek-Savaş, Antonio Ivano Triggiani, John Paul Taylor, Ian McKeith, Fabrizio Stocchi, Laura Vacca, Harald Hampel, Giovanni B Frisoni, Maria Francesca De Pandis, Laura Bonann. Abnormalities of functional cortical source connectivity of resting-state electroencephalographic alpha rhythms are similar in patients with mild cognitive impairment due to Alzheimer's and Lewy body diseases. Neurobiology of aging. vol 77. 2019-12-06. PMID:30797169. |
it can be speculated that source connectivity mostly reflects common cholinergic impairment in prodromal state of both ad and dlb, before a substantial dopaminergic derangement in the dementia stage of dlb. |
2019-12-06 |
2023-08-13 |
human |
| Rishi Sharma, Jonathan Graff-Radford, Rosa Rademakers, Bradley F Boeve, Ronald C Petersen, David T Jone. CSF1R mutation presenting as dementia with Lewy bodies. Neurocase. vol 25. issue 1-2. 2019-12-06. PMID:30968732. |
we present a case of a patient with a pathogenic variant in the csf1r gene with clinical and imaging features suggestive of dementia with lewy bodies (dlb). |
2019-12-06 |
2023-08-13 |
Not clear |
| Kie Abe, Yuhei Chib. A case of treatable dementia with Lewy bodies remarkably improved by immunotherapy. Journal of neuroimmunology. vol 330. 2019-12-03. PMID:30784774. |
we report a case of probable dementia with lewy bodies (dlb) with several findings indicating autoimmune encephalitis (e.g. |
2019-12-03 |
2023-08-13 |
Not clear |
| Nanna W Dombernowsky, Ian Law, Steen G Hasselbalc. [Confusion, loss of consciousness and unspecific visual hallucinations may be symptoms of dementia with Lewy bodies]. Ugeskrift for laeger. vol 180. issue 38. 2019-12-02. PMID:30259844. |
dementia with lewy bodies (dlb) is a common type of dementia. |
2019-12-02 |
2023-08-13 |
Not clear |
| Silvia Paciotti, Leonardo Gatticchi, Tommaso Beccari, Lucilla Parnett. Lysosomal enzyme activities as possible CSF biomarkers of synucleinopathies. Clinica chimica acta; international journal of clinical chemistry. vol 495. 2019-12-02. PMID:30922855. |
mutations on the gba gene, encoding for the lysosomal enzyme β-glucocerebrosidase (gcase), have been identified as the most common genetic risk factor involved in the development of parkinson's disease (pd) and dementia with lewy bodies (dlb), indicating a direct contribution of this enzyme to the pathogenesis of synucleinopathies. |
2019-12-02 |
2023-08-13 |
Not clear |
| Leonardo Iaccarino, Arianna Sala, Silvia Paola Caminiti, Roberto Santangelo, Sandro Iannaccone, Giuseppe Magnani, Daniela Peran. The brain metabolic signature of visual hallucinations in dementia with Lewy bodies. Cortex; a journal devoted to the study of the nervous system and behavior. vol 108. 2019-11-26. PMID:30098477. |
visual hallucinations (vh) are a core clinical feature of dementia with lewy bodies (dlb), but their specific neural substrate remains elusive. |
2019-11-26 |
2023-08-13 |
Not clear |
| Melissa J Armstrong, Slande Alliance, Pamela Corsentino, Steven T DeKosky, Angela Taylo. Cause of Death and End-of-Life Experiences in Individuals with Dementia with Lewy Bodies. Journal of the American Geriatrics Society. vol 67. issue 1. 2019-11-25. PMID:30291740. |
to investigate the natural history, cause of death, and end-of-life experiences of individuals diagnosed with dementia with lewy bodies (dlb). |
2019-11-25 |
2023-08-13 |
Not clear |
| Anna Lisa Gündner, Gonzalo Duran-Pacheco, Silke Zimmermann, Iris Ruf, Tim Moors, Karlheinz Baumann, Ravi Jagasia, Wilma D J van de Berg, Thomas Kreme. Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels. Neurobiology of disease. vol 121. 2019-11-21. PMID:30236861. |
synucleinopathies including parkinson's disease (pd) and dementia with lewy bodies (dlb) are characterized by the accumulation of abnormal α-synuclein in intraneuronal inclusions, named lewy bodies. |
2019-11-21 |
2023-08-13 |
Not clear |
| Morris, Olichney, Corey-Bloo. Psychosis in Dementia With Lewy Bodies. Seminars in clinical neuropsychiatry. vol 3. issue 1. 2019-11-20. PMID:10085191. |
prominent psychotic symptoms, particularly hallucinations and delusions, have been estimated to occur in approximately 60% of patients with dementia with lewy bodies (dlb). |
2019-11-20 |
2023-08-12 |
Not clear |
| McRitchie, Reid, Halliday, Hely, Brooks, Morri. Neuropathology of three clinical cases prospectively diagnosed as dementia with Lewy bodies. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 6. issue 2. 2019-11-20. PMID:10833584. |
consensus guidelines for the clinical and pathologic diagnosis of dementia with lewy bodies (dlb): report of the consortium on dlb international workshop. |
2019-11-20 |
2023-08-12 |
Not clear |
| John Joseph Downes, Nicholas M. Priestley, Mark Doran, Jose Ferran, Eric Ghadiali, Paul Coope. Intellectual, mnemonic, and frontal functions in dementia with Lewy bodies: A comparison with early and advanced Parkinson's disease. Behavioural neurology. vol 11. issue 3. 2019-11-20. PMID:11568418. |
both parkinson's disease (pd) and dementia with lewy bodies (dlb) share a common neuropathological marker, the presence of lewy bodies in brain stem and basal forebrain nuclei. |
2019-11-20 |
2023-08-12 |
Not clear |
| Katsuyuki Ukai, Hiroshige Fujishiro, Shuji Iritani, Norio Ozak. Long-term efficacy of donepezil for relapse of visual hallucinations in patients with dementia with Lewy bodies. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 15. issue 2. 2019-11-20. PMID:25514999. |
the use of cholinesterase inhibitors is recommended for the treatment of dementia with lewy bodies (dlb) in the guidelines of the dlb consortium. |
2019-11-20 |
2023-08-13 |
Not clear |
| Dagmar H Hepp, Dana L E Vergoossen, Evelien Huisman, Afina W Lemstra, Henk W Berendse, Annemieke J Rozemuller, Elisabeth M J Foncke, Wilma D J van de Ber. Distribution and Load of Amyloid-β Pathology in Parkinson Disease and Dementia with Lewy Bodies. Journal of neuropathology and experimental neurology. vol 75. issue 10. 2019-11-20. PMID:27516115. |
parkinson disease (pd), parkinson disease with dementia (pdd), and dementia with lewy bodies (dlb) differ clinically with regard to the presence and timing of dementia. |
2019-11-20 |
2023-08-13 |
Not clear |
| Dagmar H Hepp, Dana L E Vergoossen, Evelien Huisman, Afina W Lemstra, Henk W Berendse, Annemieke J Rozemuller, Elisabeth M J Foncke, Wilma D J van de Ber. Distribution and Load of Amyloid-β Pathology in Parkinson Disease and Dementia with Lewy Bodies. Journal of neuropathology and experimental neurology. vol 75. issue 10. 2019-11-20. PMID:27516115. |
our findings suggest that the load and extent of aβ pathology may contribute to cognitive dysfunction in pdd and the early-stage severe dementia in dlb. |
2019-11-20 |
2023-08-13 |
Not clear |