| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takeshi Iwatsub. Pathological biochemistry of alpha-synucleinopathy. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 27. issue 5. 2008-01-18. PMID:18018483. |
lewy bodies (lbs) are hallmark lesions in the brains of patients with parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2008-01-18 |
2023-08-12 |
caenorhabditis_elegans |
| F Clerici, P L Ratti, S Pomati, L Maggiore, A Elia, C Marian. Cholinergic balance in dementia with Lewy bodies: reversible worsening of Parkinsonism at rivastigmine dosage modulation. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 28. issue 5. 2008-01-17. PMID:17972045. |
we describe a patient with probable dementia with lewy bodies (dlb) whose parkinsonism worsened after administration of rivastigmine within the therapeutic dose range. |
2008-01-17 |
2023-08-12 |
Not clear |
| Kelvin C Luk, Edward G Hyde, John Q Trojanowski, Virginia M-Y Le. Sensitive fluorescence polarization technique for rapid screening of alpha-synuclein oligomerization/fibrillization inhibitors. Biochemistry. vol 46. issue 44. 2008-01-11. PMID:17927212. |
mutations in the alpha-syn gene or extra copies thereof cause familial pd or dementia with lbs (dlb) in rare kindreds, but abnormal accumulations of wildtype alpha-syn also are implicated in the pathogenesis of sporadic pd, the most common movement disorder. |
2008-01-11 |
2023-08-12 |
Not clear |
| Shahin Zibaee, Ross Jakes, Graham Fraser, Louise C Serpell, R Anthony Crowther, Michel Goeder. Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein. Journal of molecular biology. vol 374. issue 2. 2008-01-11. PMID:17936783. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are characterized by the presence of filamentous inclusions in nerve cells. |
2008-01-11 |
2023-08-12 |
human |
| Masaaki Waragai, Masaaki Nakai, Jianshe Wei, Masayo Fujita, Hideya Mizuno, Gilbert Ho, Eliezer Masliah, Hiroyasu Akatsu, Fusako Yokochi, Makoto Hashimot. Plasma levels of DJ-1 as a possible marker for progression of sporadic Parkinson's disease. Neuroscience letters. vol 425. issue 1. 2008-01-09. PMID:17720313. |
for this purpose, blood plasma samples collected from sporadic pd patients, dementia with lewy bodies (dlb) and healthy age-matched controls were analyzed by immunoblotting and enzyme-linked immunosorbent assay. |
2008-01-09 |
2023-08-12 |
Not clear |
| Kurt A Jellinger, Gregor K Wenning, Klaus Sepp. Predictors of survival in dementia with lewy bodies and Parkinson dementia. Neuro-degenerative diseases. vol 4. issue 6. 2008-01-09. PMID:17934326. |
retrospective analysis of 243 autopsy-confirmed cases of dementia with lewy bodies (dlb) and parkinson disease with dementia (pdd) showed an average age at symptom onset of 67 years and a median survival of 5 years from symptom onset. |
2008-01-09 |
2023-08-12 |
Not clear |
| S W Yong, J K Yoon, Y S An, P H Le. A comparison of cerebral glucose metabolism in Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies. European journal of neurology. vol 14. issue 12. 2008-01-08. PMID:17941855. |
parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb) share many similar aspects, and making a clinical diagnosis of one disorder over the other relies heavily on an arbitrary criterion, so-called 1-year rule. |
2008-01-08 |
2023-08-12 |
Not clear |
| Hiroyuki Kaneko, Akiyoshi Kakita, Kensaku Kasuga, Hiroaki Nozaki, Atsushi Ishikawa, Akinori Miyashita, Ryozo Kuwano, Genta Ito, Takeshi Iwatsubo, Hitoshi Takahashi, Masatoyo Nishizawa, Osamu Onodera, Sangram S Sisodia, Takeshi Ikeuch. Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 48. 2008-01-03. PMID:18045903. |
we recently reported on a novel ps1 mutation with the deletion of threonine at codon 440 (deltat440) in a familial case diagnosed as having the neocortical type of dementia with lbs (dlb) and variant ad. |
2008-01-03 |
2023-08-12 |
Not clear |
| Yasuhiro Nagahama, Tomoko Okina, Norio Suzuki, Minoru Matsuda, Kenjiro Fukao, Toshiya Mura. Classification of psychotic symptoms in dementia with Lewy bodies. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 15. issue 11. 2008-01-02. PMID:17974867. |
the aim of this study is to determine empirically a possible classification of psychotic symptoms, and identify the frequency of such symptoms in dementia with lewy bodies (dlb). |
2008-01-02 |
2023-08-12 |
Not clear |
| Kunikazu Tanji, Fumiaki Mori, Akiyoshi Kakita, Haixin Zhang, Katsumi Kito, Tetsu Kamitani, Hitoshi Takahashi, Koichi Wakabayash. Immunohistochemical localization of NUB1, a synphilin-1-binding protein, in neurodegenerative disorders. Acta neuropathologica. vol 114. issue 4. 2007-12-26. PMID:17549501. |
recently, we showed that nub1 is a synphilin-1-interacting protein and that nub1, as well as synphilin-1, accumulates in lewy bodies in parkinson's disease (pd) and dementia with lewy bodies (dlb), and glial cytoplasmic inclusions in multiple system atrophy (msa). |
2007-12-26 |
2023-08-12 |
Not clear |
| E E Benarroch, A M Schmeichel, P Sandroni, J E Parisi, P A Lo. Rostral raphe involvement in Lewy body dementia and multiple system atrophy. Acta neuropathologica. vol 114. issue 3. 2007-12-26. PMID:17639427. |
since serotonergic neurons of the rostral raphe have been implicated in depression, we sought to determine whether there is a differential involvement of these neurons in cases with clinically diagnosed dementia with lewy bodies (dlb) or msa. |
2007-12-26 |
2023-08-12 |
Not clear |
| Hanae Nakashima-Yasuda, Kunihiro Uryu, John Robinson, Sharon X Xie, Howard Hurtig, John E Duda, Steven E Arnold, Andrew Siderowf, Murray Grossman, James B Leverenz, Randy Woltjer, Oscar L Lopez, Ronald Hamilton, Debby W Tsuang, Douglas Galasko, Eliezer Masliah, Jeffrey Kaye, Christopher M Clark, Thomas J Montine, Virginia M-Y Lee, John Q Trojanowsk. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta neuropathologica. vol 114. issue 3. 2007-12-26. PMID:17653732. |
here, we investigated if tar-dna-binding protein-43 (tdp-43), the disease protein in frontotemporal lobar degeneration and ubiquitin inclusions with or without motor neuron disease as well as amyotrophic lateral sclerosis, also formed inclusions in lewy body (lb) disorders including parkinson's disease (pd) without or with dementia (pdd), and dementia with lbs (dlb) alone or in association with alzheimer's disease (ad). |
2007-12-26 |
2023-08-12 |
Not clear |
| T Sato, H Hanyu, K Hirao, S Shimizu, H Kanetaka, T Iwamot. Deep gray matter hyperperfusion with occipital hypoperfusion in dementia with Lewy bodies. European journal of neurology. vol 14. issue 11. 2007-12-20. PMID:17877736. |
although decreased occipital perfusion is a characteristic feature of dementia with lewy bodies (dlb), not all patients with dlb show a significant decreased perfusion in the occipital lobe. |
2007-12-20 |
2023-08-12 |
Not clear |
| John R Merory, Joanne E Wittwer, Christopher C Rowe, Kate E Webste. Quantitative gait analysis in patients with dementia with Lewy bodies and Alzheimer's disease. Gait & posture. vol 26. issue 3. 2007-12-13. PMID:17161601. |
quantitative gait analysis has not previously been reported for people diagnosed with dementia with lewy bodies (dlb). |
2007-12-13 |
2023-08-12 |
human |
| Frauke Boddy, Elise N Rowan, Debbie Lett, John T O'Brien, Ian G McKeith, David J Bur. Subjectively reported sleep quality and excessive daytime somnolence in Parkinson's disease with and without dementia, dementia with Lewy bodies and Alzheimer's disease. International journal of geriatric psychiatry. vol 22. issue 6. 2007-12-12. PMID:17096456. |
we compared subjective sleep quality and excessive daytime somnolence (eds) in controls, parkinson's disease with (pdd) and without dementia (pd), dementia with lewy bodies (dlb) and alzheimer's disease (ad). |
2007-12-12 |
2023-08-12 |
Not clear |
| Fredrik Boström, Linus Jönsson, Lennart Minthon, Elisabet Londo. Patients with Lewy body dementia use more resources than those with Alzheimer's disease. International journal of geriatric psychiatry. vol 22. issue 8. 2007-12-12. PMID:17195278. |
the purpose of this study was to compare resource use and costs in patients with dementia with lewy bodies (dlb) and alzheimer's disease (ad) and to assess determinants of costs of care in dlb. |
2007-12-12 |
2023-08-12 |
Not clear |
| K A Jellinge. Morphological substrates of parkinsonism with and without dementia: a retrospective clinico-pathological study. Journal of neural transmission. Supplementum. issue 72. 2007-12-10. PMID:17982882. |
a retrospective study of a 50-year autopsy series of 900 patients with the clinical diagnosis of parkinsonism (31.2% with dementia) revealed pure lewy body disease (lbd) in 84.9%, but only 44.7% with idiopathic parkinson disease (pd); 16% were associated with cerebrovascular lesions, 14.8% with alzheimer pathology; 8.9% were classified dementia with lewy bodies (dlb), 9.4% showed other degenerative disorders, and 5.6% other/ secondary parkinsonian syndromes. |
2007-12-10 |
2023-08-12 |
Not clear |
| K A Jellinge. Morphological substrates of parkinsonism with and without dementia: a retrospective clinico-pathological study. Journal of neural transmission. Supplementum. issue 72. 2007-12-10. PMID:17982882. |
a postmortem series of 330 elderly patients clinically diagnosed as parkinsonism with (37.6%) and without dementia showed that ipd, braak stages 3-5 were rarely associated with cognitive impairment, which was frequently seen in ipd with associated alzheimer pathology (35.5%), dlb (33.9%), and in alzheimer disease (ad) or mixed dementia (17%), whereas it almost never was associated with minor cerebrovascular lesions. |
2007-12-10 |
2023-08-12 |
Not clear |
| Kenji Wada-Isoe, Michio Kitayama, Kazuhiro Nakaso, Kenji Nakashim. Diagnostic markers for diagnosing dementia with Lewy bodies: CSF and MIBG cardiac scintigraphy study. Journal of the neurological sciences. vol 260. issue 1-2. 2007-12-06. PMID:17459416. |
this study examined the diagnostic value of cerebrospinal fluid (csf) markers and iodine-123 metaiodobenzylguanidine ((123)i-mibg) cardiac scintigraphy in distinguishing dementia with lewy bodies (dlb) from alzheimer's disease (ad). |
2007-12-06 |
2023-08-12 |
Not clear |
| Margaret A Piggott, Clive G Ballard, Elise Rowan, Clive Holmes, Ian G McKeith, Evelyn Jaros, Robert H Perry, Elaine K Perr. Selective loss of dopamine D2 receptors in temporal cortex in dementia with Lewy bodies, association with cognitive decline. Synapse (New York, N.Y.). vol 61. issue 11. 2007-12-06. PMID:17663455. |
dementia with lewy bodies (dlb) is a progressive dementia frequently accompanied by psychotic symptoms. |
2007-12-06 |
2023-08-12 |
Not clear |