| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Sekaninova, M Mestanik, A Mestanikova, A Hamrakova, I Tonhajzerov. Novel approach to evaluate central autonomic regulation in attention deficit/hyperactivity disorder (ADHD). Physiological research. vol 68. issue 4. 2020-02-10. PMID:31177787. |
according to current knowledge, adhd is defined as a biological dysfunction of central nervous system with genetically or organically defined deficits in noradrenergic and dopaminergic neurotransmission associated with structural abnormalities, especially in prefronto-striatal regions. |
2020-02-10 |
2023-08-13 |
Not clear |
| Calwing Liao, Alexandre D Laporte, Dan Spiegelman, Fulya Akçimen, Ridha Joober, Patrick A Dion, Guy A Roulea. Transcriptome-wide association study of attention deficit hyperactivity disorder identifies associated genes and phenotypes. Nature communications. vol 10. issue 1. 2020-01-06. PMID:31575856. |
furthermore, pathway enrichment identifies dopaminergic and norepinephrine pathways, which are highly relevant for adhd. |
2020-01-06 |
2023-08-13 |
Not clear |
| Radek Ptacek, Simon Weissenberger, Ellen Braaten, Martina Klicperova-Baker, Michal Goetz, Jiri Raboch, Martina Vnukova, George B Stefan. Clinical Implications of the Perception of Time in Attention Deficit Hyperactivity Disorder (ADHD): A Review. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-12-06. PMID:31129679. |
although adhd has been associated with neurologic abnormalities in the mesolimbic and dopaminergic systems, recent studies have found that when individuals with adhd are treated medically, their perception of time tends to normalize. |
2019-12-06 |
2023-08-13 |
Not clear |
| Yafit Gabay, Elham Shahbari-Khateb, Avi Mendelsoh. Feedback Timing Modulates Probabilistic Learning in Adults with ADHD. Scientific reports. vol 8. issue 1. 2019-10-24. PMID:30341358. |
to this effect, we recently showed that feedback-based procedural learning is selectively impaired in adhd, results that coincide with dopaminergic alterations associated with adhd. |
2019-10-24 |
2023-08-13 |
human |
| Roland van Rensburg, Helgard Pieter Meyer, Sonia Anne Hitchcock, Christian Edward Schule. Screening for Adult ADHD in Patients with Fibromyalgia Syndrome. Pain medicine (Malden, Mass.). vol 19. issue 9. 2019-08-05. PMID:29099955. |
this study aimed to assess the potential co-occurrence of fms and adult attention deficit hyperactivity disorder (adhd), a chronic neurodevelopmental disorder also associated with impaired cognition and dopaminergic function. |
2019-08-05 |
2023-08-13 |
Not clear |
| N M Myer, J R Boland, S V Faraon. Pharmacogenetics predictors of methylphenidate efficacy in childhood ADHD. Molecular psychiatry. vol 23. issue 9. 2019-07-31. PMID:29230023. |
both methylphenidate and amphetamine modulate extracellular catecholamine levels through interaction with dopaminergic, adrenergic and serotonergic system components; it is therefore likely that catecholaminergic molecular components influence the effects of adhd treatment. |
2019-07-31 |
2023-08-13 |
Not clear |
| Manfred Gerlach, Manu Sharma, Marcel Romanos, Klaus-Peter Lesch, Susanne Walitza, H Annette Conzelmann, Rejko Krüger, Tobias J Renne. Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder. Attention deficit and hyperactivity disorders. vol 11. issue 1. 2019-07-19. PMID:30927235. |
studies have strongly suggested a disturbed regulation of dopaminergic neurotransmission in attention-deficit/hyperactivity disorder (adhd) and parkinson's disease (pd). |
2019-07-19 |
2023-08-13 |
Not clear |
| Lorena Oliveira de Matos, Ana Luiza de Araujo Lima Reis, Lorena Terene Lopes Guerra, Leonardo de Oliveira Guarnieri, Muiara Aparecida Moraes, Nayara Soares Sena Aquino, Raphael E Szawka, Grace Schenatto Pereira, Bruno Rezende Souz. l-Dopa treatment during perinatal development leads to different behavioral alterations in female vs. male juvenile Swiss mice. Pharmacology, biochemistry, and behavior. vol 173. 2019-05-22. PMID:30102946. |
alterations in dopaminergic signaling and neurodevelopment are associated with many neuropsychiatric disorders, such as attention deficit and hyperactivity disorder (adhd), autism, and schizophrenia. |
2019-05-22 |
2023-08-13 |
mouse |
| Karen Curtin, Annette E Fleckenstein, Brooks R Keeshin, Deborah A Yurgelun-Todd, Perry F Renshaw, Ken R Smith, Glen R Hanso. Increased risk of diseases of the basal ganglia and cerebellum in patients with a history of attention-deficit/hyperactivity disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 13. 2019-03-26. PMID:30209407. |
attention-deficit/hyperactivity disorder (adhd) is marked by an ongoing pattern of inattention and/or hyperactivity and involves dysregulated dopaminergic pathways. |
2019-03-26 |
2023-08-13 |
human |
| Karen Curtin, Annette E Fleckenstein, Brooks R Keeshin, Deborah A Yurgelun-Todd, Perry F Renshaw, Ken R Smith, Glen R Hanso. Increased risk of diseases of the basal ganglia and cerebellum in patients with a history of attention-deficit/hyperactivity disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 13. 2019-03-26. PMID:30209407. |
dopaminergic agents (i.e., amphetamine and methylphenidate) are thus prescribed to treat adhd. |
2019-03-26 |
2023-08-13 |
human |
| R N Mustafin, R F Enikeeva, S B Malykh, R G Valinurov, E K Khusnutdinov. [Genetics and epigenetics of attention deficit hyperactivity disorder]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 118. issue 9. 2019-03-25. PMID:30335081. |
association studies have shown the relationship between adhd and genes of dopaminergic (drd4, drd5, slc6a3), serotoninergic (htr1b, 5-httlpr), glutamatergic (mglur, ndrg2) systems, metabolic pathways (slc2a3, slc6a4, cdh13, cfod1, gfod1), membrane proteins (kchip1, itga1, snap-25) as well as tumour-suppressor (ndrg2, nf1) and cytokine genes. |
2019-03-25 |
2023-08-13 |
Not clear |
| Hiromasa Satoh, Hidenori Suzuki, Fumihito Saito. Downregulation of Dopamine D1-like Receptor Pathways of GABAergic Interneurons in the Anterior Cingulate Cortex of Spontaneously Hypertensive Rats. Neuroscience. vol 394. 2019-03-01. PMID:30394321. |
deficits in dopaminergic function are thought to underlie attention-deficit/hyperactivity disorder (adhd). |
2019-03-01 |
2023-08-13 |
rat |
| Jun Ho Hong, In Wook Hwang, Myung Ho Lim, Ho Jang Kwon, Han Jun Ji. Genetic associations between ADHD and dopaminergic genes (DAT1 and DRD4) VNTRs in Korean children. Genes & genomics. vol 40. issue 12. 2019-02-22. PMID:30099719. |
genetic associations between adhd and dopaminergic genes (dat1 and drd4) vntrs in korean children. |
2019-02-22 |
2023-08-13 |
Not clear |
| Jun Ho Hong, In Wook Hwang, Myung Ho Lim, Ho Jang Kwon, Han Jun Ji. Genetic associations between ADHD and dopaminergic genes (DAT1 and DRD4) VNTRs in Korean children. Genes & genomics. vol 40. issue 12. 2019-02-22. PMID:30099719. |
it is well known that dopaminergic genes affect the development of attention deficit hyperactivity disorder (adhd) in various populations. |
2019-02-22 |
2023-08-13 |
Not clear |
| Johanna Inhyang Kim, Jae-Won Kim, Jong-Min Lee, Hyuk Jin Yun, Chul-Ho Sohn, Min-Sup Shin, Bongseog Kim, Jonghee Chae, Jaewoo Roh, Bung-Nyun Ki. Interaction between DRD2 and lead exposure on the cortical thickness of the frontal lobe in youth with attention-deficit/hyperactivity disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 82. 2019-01-22. PMID:29169998. |
the d2 receptor is also mainly located in the pfc, and animal studies show that lead exposure affects the dopaminergic system of the frontal lobe, indicating an overlap in neural correlates of adhd, drd2, and lead exposure. |
2019-01-22 |
2023-08-13 |
Not clear |
| Jochen Bauer, Anne Werner, Waldemar Kohl, Harald Kugel, Anna Shushakova, Anya Pedersen, Patricia Ohrman. Hyperactivity and impulsivity in adult attention-deficit/hyperactivity disorder is related to glutamatergic dysfunction in the anterior cingulate cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 7. 2019-01-14. PMID:27973969. |
attention-deficit/hyperactivity disorder (adhd) is closely linked to the dysregulation of dopaminergic and noradrenergic neurotransmission in the fronto-striatal neural network, including the anterior cingulate cortex (acc) and the dorsolateral prefrontal cortex (dlpfc). |
2019-01-14 |
2023-08-13 |
Not clear |
| Hartmut Heinrich, Juliane Grunitz, Valeska Stonawski, Stefan Frey, Simone Wahl, Björn Albrecht, Tamme W Goecke, Matthias W Beckmann, Johannes Kornhuber, Peter A Fasching, Gunther H Moll, Anna Eichle. Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age. Scientific reports. vol 7. issue 1. 2018-12-19. PMID:28630479. |
for cpg sites at genes of the dopaminergic (comt, ankk1) and the neurotrophic (bdnf, ngfr) system, associations with the nogo-p3 as well as adhd symptom severity were found suggesting that these systems are involved in response control deficits in adhd. |
2018-12-19 |
2023-08-13 |
human |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
dopaminergic deficits in the prefrontal cortex and striatum have been attributed to the pathogenesis of attention-deficit hyperactivity disorder (adhd). |
2018-11-05 |
2023-08-13 |
rat |
| Andan Qian, Xin Wang, Huiru Liu, Jiejie Tao, Jiejie Zhou, Qiong Ye, Jiance Li, Chuang Yang, Jingliang Cheng, Ke Zhao, Meihao Wan. Dopamine D4 Receptor Gene Associated with the Frontal-Striatal-Cerebellar Loop in Children with ADHD: A Resting-State fMRI Study. Neuroscience bulletin. vol 34. issue 3. 2018-09-18. PMID:29564731. |
attention deficit hyperactivity disorder (adhd) is a common childhood neuropsychiatric disorder that has been linked to the dopaminergic system. |
2018-09-18 |
2023-08-13 |
human |
| Johanna Inhyang Kim, Jae Hyun Yoo, Dohyun Kim, Bumseok Jeong, Bung-Nyun Ki. The effects of GRIN2B and DRD4 gene variants on local functional connectivity in attention-deficit/hyperactivity disorder. Brain imaging and behavior. vol 12. issue 1. 2018-08-27. PMID:28258362. |
based on the interplay between dopaminergic and glutamatergic systems, n-methyl-d-asparate (nmda) receptor genes are thought to be involved in the pathophysiology of adhd. |
2018-08-27 |
2023-08-13 |
human |