| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Blake L Elliott, Kimberlee D'Ardenne, Prerona Mukherjee, Julie B Schweitzer, Samuel M McClur. Limbic and Executive Meso- and Nigrostriatal Tracts Predict Impulsivity Differences in Attention-Deficit/Hyperactivity Disorder. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2021-08-26. PMID:34051394. |
we tested whether human midbrain pathways (where dopaminergic cell bodies originate) between the substantia nigra (sn) and ventral tegmental area (vta) and the striatum differed between participants with adhd and typically developing adolescent and young adult participants. |
2021-08-26 |
2023-08-13 |
human |
| Shih-Hsien Lin, Mei Hung Chi, I Hui Lee, Kao Chin Chen, Ying Chun Tai, Wei Jen Yao, Nan Tsing Chiu, Dong-Yu Yang, Chun-Yu Lin, Po See Chen, Yen Kuang Yan. A pilot study on the association between the blood oxygen level-dependent signal in the reward system and dopamine transporter availability in adults with attention deficit hyperactivity disorder. CNS spectrums. vol 26. issue 3. 2021-08-09. PMID:32308185. |
it is well-known that attention deficit hyperactivity disorder (adhd) is associated with changes in the dopaminergic system. |
2021-08-09 |
2023-08-13 |
Not clear |
| Shih-Hsien Lin, Mei Hung Chi, I Hui Lee, Kao Chin Chen, Ying Chun Tai, Wei Jen Yao, Nan Tsing Chiu, Dong-Yu Yang, Chun-Yu Lin, Po See Chen, Yen Kuang Yan. A pilot study on the association between the blood oxygen level-dependent signal in the reward system and dopamine transporter availability in adults with attention deficit hyperactivity disorder. CNS spectrums. vol 26. issue 3. 2021-08-09. PMID:32308185. |
however, the relationship between central dopaminergic tone and the blood oxygen level-dependent (bold) signal during receipt of rewards and penalties in the corticostriatal pathway in adults with adhd is unclear. |
2021-08-09 |
2023-08-13 |
Not clear |
| Ditte Olsen, Niels Wellner, Mathias Kaas, Inge E M de Jong, Florence Sotty, Michael Didriksen, Simon Glerup, Anders Nykjae. Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33495438. |
however, the underlying pathophysiology of adhd and how this relates to dopaminergic transmission remains to be fully understood. |
2021-06-28 |
2023-08-13 |
mouse |
| Nagahide Takahashi, Tomoko Nishimura, Taeko Harada, Akemi Okumura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Jeffrey H Newcorn, Nori Takei, Kenji J Tsuchiy. Polygenic risk score analysis revealed shared genetic background in attention deficit hyperactivity disorder and narcolepsy. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32801330. |
gene-set enrichment analyses revealed that pathways related to dopaminergic signaling, immune systems, iron metabolism, and glial cell function involved in both adhd and narcolepsy. |
2021-06-18 |
2023-08-13 |
Not clear |
| Daryl A Guthrie, Carmen Klein Herenbrink, Matthew Domenic Lycas, Therese Ku, Alessandro Bonifazi, Brian T DeVree, Signe Mathiasen, Jonathan A Javitch, Jonathan B Grimm, Luke Lavis, Ulrik Gether, Amy Hauck Newma. Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter. ACS chemical neuroscience. vol 11. issue 20. 2021-06-18. PMID:32926777. |
the dopamine transporter (dat) is critical for spatiotemporal control of dopaminergic neurotransmission and is the target for therapeutic agents, including adhd medications, and abused substances, such as cocaine. |
2021-06-18 |
2023-08-13 |
Not clear |
| Nina Roth Mota, Geert Poelmans, Marieke Klein, Bàrbara Torrico, Noèlia Fernàndez-Castillo, Bru Cormand, Andreas Reif, Barbara Franke, Alejandro Arias Vásque. Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31896117. |
we tested the association of dopaminergic and circadian rhythm gene sets with adhd, body mass index (bmi), and obesity (using gwas data of n = 53,293, n = 681,275, and n = 98,697, respectively). |
2021-05-27 |
2023-08-13 |
Not clear |
| Nina Roth Mota, Geert Poelmans, Marieke Klein, Bàrbara Torrico, Noèlia Fernàndez-Castillo, Bru Cormand, Andreas Reif, Barbara Franke, Alejandro Arias Vásque. Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:31896117. |
the dopaminergic gene set was associated with both adhd (p = 5.81 × 10 |
2021-05-27 |
2023-08-13 |
Not clear |
| Lisiane de Santana Souza, Priscila Albuquerque de Siqueira, Arlete Fernandes, Robertta Silva Martins, Regina Célia Cussa Kubrusly, Roberto Paes-de-Carvalho, Rodrigo A Cunha, Alexandre Dos Santos-Rodrigues, Pablo Pandolf. Role of Neuropeptide S on Behavioural and Neurochemical Changes of an Animal Model of Attention-Deficit/Hyperactivity Disorder. Neuroscience. vol 448. 2021-05-14. PMID:32976984. |
since npsr activation increases dopaminergic transmission, we now tested if npsr modulates behavioural and neurochemical alterations displayed by an animal model of attention-deficit/hyperactivity disorder (adhd), spontaneous hypertensive rats (shr), compared to its control strain, wistar kyoto rats (wky). |
2021-05-14 |
2023-08-13 |
rat |
| Natalia P Kurzina, Anna B Volnova, Irina Y Aristova, Raul R Gainetdino. A New Paradigm for Training Hyperactive Dopamine Transporter Knockout Rats: Influence of Novel Stimuli on Object Recognition. Frontiers in behavioral neuroscience. vol 15. 2021-05-13. PMID:33967714. |
attention deficit hyperactivity disorder (adhd) is believed to be connected with a high level of hyperactivity caused by alterations of the control of dopaminergic transmission in the brain. |
2021-05-13 |
2023-08-13 |
rat |
| Hila Z Gvirts Probolovski, Anat Daha. The Potential Role of Dopamine in Mediating Motor Function and Interpersonal Synchrony. Biomedicines. vol 9. issue 4. 2021-05-02. PMID:33916451. |
we present attention deficit hyperactivity disorder (adhd) as an example of a disorder that involves the dopaminergic system and describe deficits in motor and interpersonal synchrony. |
2021-05-02 |
2023-08-13 |
Not clear |
| Mrinaal Valmiki, Peter Fawzy, Surbhi Valmiki, Mohamed A Aid, Ali R Chaitou, Maria Zahid, Safeera Kha. Reinforcement and Compensatory Mechanisms in Attention-Deficit Hyperactivity Disorder: A Systematic Review of Case-Control Studies. Cureus. vol 13. issue 3. 2021-04-10. PMID:33833929. |
ventral striatal hypo-responsiveness, orbitofrontal cortex, and dopaminergic status in the brain are related to the pathogenesis of adhd. |
2021-04-10 |
2023-08-13 |
human |
| Marco Pozzi, Silvana Bertella, Erika Gatti, Gabriëlla G A M Peeters, Carla Carnovale, Stefania Zambrano, Maria Nobil. Emerging drugs for the treatment of attention-deficit hyperactivity disorder (ADHD). Expert opinion on emerging drugs. vol 25. issue 4. 2021-03-16. PMID:32938246. |
current pharmacological treatments for adhd are based on stimulant or non-stimulant medications, targeting dopaminergic and noradrenergic systems in the frontal cortex and dopaminergic system in the basal ganglia. |
2021-03-16 |
2023-08-13 |
Not clear |
| Da Hee Jung, Sung Min Ahn, Malk Eun Pak, Hong Ju Lee, Young Jin Jung, Ki Bong Kim, Yong-Il Shin, Hwa Kyoung Shin, Byung Tae Cho. Therapeutic effects of anodal transcranial direct current stimulation in a rat model of ADHD. eLife. vol 9. 2021-03-15. PMID:32955434. |
most therapeutic candidates for treating attention-deficit hyperactivity disorder (adhd) have focused on modulating the dopaminergic neurotransmission system with neurotrophic factors. |
2021-03-15 |
2023-08-13 |
rat |
| Glenda E Gillies, Kanwar Virdee, Ilse Pienaar, Felwah Al-Zaid, Jeffrey W Dalle. Enduring, Sexually Dimorphic Impact of In Utero Exposure to Elevated Levels of Glucocorticoids on Midbrain Dopaminergic Populations. Brain sciences. vol 7. issue 1. 2021-03-04. PMID:28042822. |
sex-specific neurobiological programming of midbrain dopaminergic systems may, therefore, have psychopathological relevance for the sex bias commonly found in brain disorders associated with these systems, and which have a neurodevelopmental component, including schizophrenia, adhd (attention/deficit hyperactivity disorders), autism, depression and substance abuse. |
2021-03-04 |
2023-08-13 |
human |
| Georg C Ziegler, Christoph Röser, Tobias Renner, Tim Hahn, Ann-Christine Ehlis, Heike Weber, Astrid Dempfle, Susanne Walitza, Christian Jacob, Marcel Romanos, Andreas J Fallgatter, Andreas Reif, Klaus-Peter Lesc. KCNJ6 variants modulate reward-related brain processes and impact executive functions in attention-deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 183. issue 5. 2021-02-16. PMID:31099984. |
kcnj6, encoding a potassium channel subunit, regulates the excitability of dopaminergic neurons and is expressed in attention-deficit/hyperactivity disorder (adhd)-relevant brain regions. |
2021-02-16 |
2023-08-13 |
Not clear |
| Jae-Won Choi, A-Hyun Jung, Sojeong Nam, Kyoung Min Kim, Jun Won Kim, Soo Yeon Kim, Bung-Nyun Kim, Jae-Won Ki. Interaction between lead and noradrenergic genotypes affects neurocognitive functions in attention-deficit/hyperactivity disorder: a case control study. BMC psychiatry. vol 20. issue 1. 2020-12-29. PMID:32791971. |
we aimed to evaluate neurocognitive functions associated with lead in the blood and the interactions between lead and dopaminergic or noradrenergic pathway-related genotypes in youths with adhd. |
2020-12-29 |
2023-08-13 |
Not clear |
| Zuhair I Abdulla, Bahar Pahlevani, Kerstin H Lundgren, Jordan L Pennington, Kenea C Udobi, Kim B Seroogy, Matthew R Skelto. Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice. Journal of molecular neuroscience : MN. vol 70. issue 1. 2020-10-08. PMID:31520365. |
of particular interest related to cr physiology are dopaminergic neurons, as many ccds patients have adhd and cr has been implicated in dopamine-associated neurodegenerative disorders, such as parkinson's and huntington's diseases. |
2020-10-08 |
2023-08-13 |
mouse |
| Andrieke J A M Thissen, Janita Bralten, Nanda N J Rommelse, Alejandro Arias-Vasquez, Corina U Greven, Dirk Heslenfeld, Marjolein Luman, Jaap Oosterlaan, Pieter J Hoekstra, Catharina Hartman, Barbara Franke, Jan K Buitelaa. The role of age in association analyses of ADHD and related neurocognitive functioning: A proof of concept for dopaminergic and serotonergic genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 168. issue 6. 2020-10-01. PMID:25586935. |
the role of age in association analyses of adhd and related neurocognitive functioning: a proof of concept for dopaminergic and serotonergic genes. |
2020-10-01 |
2023-08-13 |
Not clear |
| Andrieke J A M Thissen, Janita Bralten, Nanda N J Rommelse, Alejandro Arias-Vasquez, Corina U Greven, Dirk Heslenfeld, Marjolein Luman, Jaap Oosterlaan, Pieter J Hoekstra, Catharina Hartman, Barbara Franke, Jan K Buitelaa. The role of age in association analyses of ADHD and related neurocognitive functioning: A proof of concept for dopaminergic and serotonergic genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 168. issue 6. 2020-10-01. PMID:25586935. |
the current study explored the association between dopaminergic and serotonergic genes, adhd symptoms, and neurocognitive functioning in relation to age. |
2020-10-01 |
2023-08-13 |
Not clear |