| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin-Rong Wu, Xiao-Na Zhu, Yuan-Bo Pan, Xue Gu, Xian-Dong Liu, Si Chen, Yu Zhang, Tian-Le Xu, Nan-Jie Xu, Suya Su. Amygdala neuronal dyshomeostasis via 5-HT receptors mediates mood and cognitive defects in Alzheimer's disease. Aging cell. 2024-05-08. PMID:38716507. |
amygdala neuronal dyshomeostasis via 5-ht receptors mediates mood and cognitive defects in alzheimer's disease. |
2024-05-08 |
2024-05-27 |
Not clear |
| Ruben P Dörfel, Joan M Arenas-Gomez, Claus Svarer, Melanie Ganz, Gitte M Knudsen, Jonas E Svensson, Pontus Plavén-Sigra. Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET-derived features. GeroScience. 2024-04-26. PMID:38668887. |
brain serotonin 2a receptors (5-ht2ar) show a particularly profound age-related decline and are also reduced in neurodegenerative disorders, such as alzheimer's disease. |
2024-04-26 |
2024-04-28 |
human |
| Arubala P Reddy, Priyanka Rawat, Nicholas Rohr, Razelle Alvir, Jasbir Bisht, Mst Anika Bushra, Jennifer Luong, Aananya P Redd. Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis. Aging and disease. 2024-04-12. PMID:38607731. |
the neurotransmitter serotonin (5-hydroxytryptamine, 5-ht) is implicated mainly in alzheimer's disease (ad) and reported to be responsible for several processes and roles in the human body, such as regulating sleep, food intake, sexual behavior, anxiety, and drug abuse. |
2024-04-12 |
2024-04-15 |
human |
| Shahnaz Saednia, Saeed Emami, Masoud Moslehi, Seyed Jalal Hosseinimeh. Insights into the development of European journal of medicinal chemistry. vol 270. 2024-03-31. PMID:38555856. |
insights into the development of serotonergic (5-hydroxytryptamine; 5-ht) receptors play critical roles in neurological and psychological disorders such as schizophrenia, anxiety, depression, and alzheimer's diseases. |
2024-03-31 |
2024-04-03 |
Not clear |
| Aaron Del Pozo, Kevin M Knox, Leanne M Lehmann, Stephanie Davidson, Seongheon Leo Rho, Suman Jayadev, Melissa Barker-Halisk. Chronic evoked seizures in young pre-symptomatic APP/PS1 mice induce serotonin changes and accelerate onset of Alzheimer's disease-related neuropathology. Progress in neurobiology. 2024-03-14. PMID:38484965. |
chronic evoked seizures in young pre-symptomatic app/ps1 mice induce serotonin changes and accelerate onset of alzheimer's disease-related neuropathology. |
2024-03-14 |
2024-03-17 |
mouse |
| Dmitrii V Eremin, Elena M Kondaurova, Aleksander Ya Rodnyy, Camilla A Molobekova, Dmitrii A Kudlay, Vladimir S Naumenk. Serotonin Receptors as a Potential Target in the Treatment of Alzheimer's Disease. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462447. |
serotonin receptors as a potential target in the treatment of alzheimer's disease. |
2024-03-10 |
2024-03-14 |
Not clear |
| Kanchan Bhardwaj, Rashi Bhargav, Jiri Patocka, Ruchi Sharma, Zdenka Navratilova, Patrik Oleksak, Kamil Kuc. Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review. Mini reviews in medicinal chemistry. 2024-02-07. PMID:38321903. |
the phytochemical profile had potent in-vivo and in-vitro efficacy in neuroprotection, nerve function, memory enhancement, cognitive disorders, anxiety and depression, anti-oxidant, psychological conditions, increasing serotonin concentration in synapse anxiolytic, tranquilizing, anti-stress, neurodegenerative (alzheimer's disease and parkinson), anti-inflammatory and analgesic. |
2024-02-07 |
2024-02-09 |
Not clear |
| Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzli. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT Journal of medicinal chemistry. 2024-01-08. PMID:38190615. |
first-in-class selenium-containing potent serotonin receptor 5-ht alzheimer's disease (ad) has a complex and not-fully-understood etiology. |
2024-01-08 |
2024-01-10 |
Not clear |
| Nicole C Reyna, Benjamin J Clark, Derek A Hamilton, Nathan S Pentkowsk. Anxiety and Alzheimer's disease pathogenesis: focus on 5-HT and CRF systems in 3xTg-AD and TgF344-AD animal models. Frontiers in aging neuroscience. vol 15. 2023-12-11. PMID:38076543. |
anxiety and alzheimer's disease pathogenesis: focus on 5-ht and crf systems in 3xtg-ad and tgf344-ad animal models. |
2023-12-11 |
2023-12-17 |
Not clear |
| Jing Tian, Eric Du, Lan Gu. Mitochondrial Interaction with Serotonin in Neurobiology and Its Implication in Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-12-01. PMID:38025801. |
mitochondrial interaction with serotonin in neurobiology and its implication in alzheimer's disease. |
2023-12-01 |
2023-12-10 |
Not clear |
| Olivia Lu, Taimur Kouser, Irina A Skylar-Scot. Alzheimer's disease and epilepsy: shared neuropathology guides current and future treatment strategies. Frontiers in neurology. vol 14. 2023-11-08. PMID:37936917. |
additionally, there are practical treatment considerations in patients with co-morbid ad and epilepsy-namely, there is a higher risk of seizures associated with medications commonly prescribed for alzheimer's disease patients, including antidepressants and antipsychotics such as trazodone, serotonin norepinephrine reuptake inhibitors (snris), and first-generation neuroleptics. |
2023-11-08 |
2023-11-20 |
Not clear |
| Cynthia Janku, Priya V Engel, Kisan Patel, Elias Girald. The 100 Most Cited Kluver-Bucy Research Articles: A Bibliometric Analysis. Cureus. vol 15. issue 9. 2023-10-20. PMID:37854727. |
kluver-bucy syndrome (kbs) is a rare neuropsychiatric disorder characterized by hyperorality, hypersexuality, bulimia, visual agnosia, and amnesia due to lesions affecting bilateral temporal lobes. it is attributed to a multitude of causes, including stroke, herpes simplex encephalitis, alzheimer's disease, and head trauma. current treatments for kbs include symptomatic management with antipsychotics, mood stabilizers, carbamazepine, and selective serotonin reuptake inhibitors. |
2023-10-20 |
2023-11-08 |
Not clear |
| Anna-Lena Richter, Marlies Diepeveen-de Bruin, Michiel G J Balvers, Lisette C P G M De Groot, Peter Paul De Deyn, Sebastiaan Engelborghs, Renger F Witkamp, Yannick Vermeire. Association between low vitamin D status, serotonin and clinico-bio-behavioral parameters in Alzheimer's disease. Dementia and geriatric cognitive disorders. 2023-10-08. PMID:37806302. |
association between low vitamin d status, serotonin and clinico-bio-behavioral parameters in alzheimer's disease. |
2023-10-08 |
2023-10-15 |
Not clear |
| Katarzyna Grychowska, Uriel López-Sánchez, Mathieu Vitalis, Geoffrey Canet, Grzegorz Satała, Agnieszka Olejarz-Maciej, Joanna Gołębiowska, Rafał Kurczab, Wojciech Pietruś, Monika Kubacka, Christophe Moreau, Maria Walczak, Klaudia Blicharz-Futera, Xavier Bantreil, Gilles Subra, Andrzej J Bojarski, Frédéric Lamaty, Carine Becamel, Charleine Zussy, Séverine Chaumont-Dubel, Piotr Popik, Hugues Nury, Philippe Marin, Laurent Givalois, Paweł Zajde. Superiority of the Triple-Acting 5-HT Journal of medicinal chemistry. 2023-10-05. PMID:37797083. |
superiority of the triple-acting 5-ht the multifactorial origin and neurochemistry of alzheimer's disease (ad) call for the development of multitarget treatment strategies. |
2023-10-05 |
2023-10-07 |
Not clear |
| Hari Shanker Sharma, Lianyuan Feng, Dafin F Muresanu, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Ala Nozari, Igor Bryukhovetskiy, Igor Manzhulo, Lars Wiklund, Aruna Sharm. Stress induced exacerbation of Alzheimer's disease brain pathology is thwarted by co-administration of nanowired cerebrolysin and monoclonal amyloid beta peptide antibodies with serotonin 5-HT6 receptor antagonist SB-399885. International review of neurobiology. vol 171. 2023-10-02. PMID:37783559. |
stress induced exacerbation of alzheimer's disease brain pathology is thwarted by co-administration of nanowired cerebrolysin and monoclonal amyloid beta peptide antibodies with serotonin 5-ht6 receptor antagonist sb-399885. |
2023-10-02 |
2023-10-07 |
Not clear |
| Hari Shanker Sharma, Lianyuan Feng, Dafin F Muresanu, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Ala Nozari, Igor Bryukhovetskiy, Igor Manzhulo, Lars Wiklund, Aruna Sharm. Stress induced exacerbation of Alzheimer's disease brain pathology is thwarted by co-administration of nanowired cerebrolysin and monoclonal amyloid beta peptide antibodies with serotonin 5-HT6 receptor antagonist SB-399885. International review of neurobiology. vol 171. 2023-10-02. PMID:37783559. |
our observations clearly show that restraint stress significantly exacerbate alzheimer's disease brain pathology and nanodelivery of a multimodal drug cerebrolysin together with monoclonal antibodies (mab) to amyloid beta peptide (aβp) together with a serotonin 5-ht6 receptor antagonist sb399885 significantly thwarted alzheimer's disease brain pathology exacerbated by restraint stress, not reported earlier. |
2023-10-02 |
2023-10-07 |
Not clear |
| Koel Sinha, Ananya Chakraborty, Zishan Ahmed, Piyali Mukherjee, Priyanka Dutta, Chitrangada Das Mukhopadhyay, Chirasree RoyChaudhur. Molecularly Imprinted Polymer Interface on Screen-Printed ZnO Nanorod Field Effect Transistors for Serotonin Detection in Clinical Samples. ACS biomaterials science & engineering. 2023-09-25. PMID:37747783. |
ultrasensitive detection of serotonin is crucial for the early diagnosis of several diseases like parkinson's and alzheimer's. |
2023-09-25 |
2023-10-07 |
Not clear |
| Sylwia Sudoł-Tałaj, Katarzyna Kucwaj-Brysz, Sabina Podlewska, Rafał Kurczab, Grzegorz Satała, Barbara Mordyl, Monika Głuch-Lutwin, Natalia Wilczyńska-Zawal, Magdalena Jastrzębska-Więsek, Kinga Czarnota-Łydka, Kinga Kurowska, Monika Kubacka, Ewa Żesławska, Wojciech Nitek, Agnieszka Olejarz-Maciej, Agata Doroz-Płonka, Anna Partyka, Gniewomir Latacz, Anna Wesołowska, Jadwiga Handzli. Hydrophobicity modulation via the substituents at positions 2 and 4 of 1,3,5-triazine to enhance therapeutic ability against Alzheimer's disease for potent serotonin 5-HT European journal of medicinal chemistry. vol 260. 2023-09-01. PMID:37657272. |
hydrophobicity modulation via the substituents at positions 2 and 4 of 1,3,5-triazine to enhance therapeutic ability against alzheimer's disease for potent serotonin 5-ht alzheimer's disease (ad), a neurodegenerative disorder with a complex aetiology, is the most common memory dysfunction particularly affecting the elderly. |
2023-09-01 |
2023-09-07 |
Not clear |
| Kinga Czarnota-Łydka, Sylwia Sudoł-Tałaj, Katarzyna Kucwaj-Brysz, Rafał Kurczab, Grzegorz Satała, Modesto de Candia, Francesco Samarelli, Cosimo Damiano Altomare, Alessia Carocci, Alexia Barbarossa, Ewa Żesławska, Monika Głuch-Lutwin, Barbara Mordyl, Monika Kubacka, Natalia Wilczyńska-Zawal, Magdalena Jastrzębska-Więsek, Anna Partyka, Nadia Khan, Małgorzata Więcek, Wojciech Nitek, Ewelina Honkisz-Orzechowska, Gniewomir Latacz, Anna Wesołowska, Antonio Carrieri, Jadwiga Handzli. Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT European journal of medicinal chemistry. vol 259. 2023-08-11. PMID:37567058. |
synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-ht alzheimer's disease is becoming a growing problem increasing at a tremendous rate. |
2023-08-11 |
2023-08-16 |
Not clear |
| Teodora Z Markova, Claire J Ciampa, Jourdan H Parent, Molly R LaPoint, Mark D'Esposito, William J Jagust, Anne S Berr. Poorer aging trajectories are associated with elevated serotonin synthesis capacity. Molecular psychiatry. 2023-07-17. PMID:37460847. |
the dorsal raphe nucleus (drn) is one of the earliest targets of alzheimer's disease-related tau pathology and is a major source of brain serotonin. |
2023-07-17 |
2023-08-14 |
Not clear |