All Relations between Alzheimer Disease and retina

Publication Sentence Publish Date Extraction Date Species
Fabio Casciano, Enrico Zauli, Claudio Celeghini, Lorenzo Caruso, Arianna Gonelli, Giorgio Zauli, Angela Pignatell. Retinal Alterations Predict Early Prodromal Signs of Neurodegenerative Disease. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338966. similarly, the visual cortex is modified by the neurofibrillary tangles and neuritic amyloid β plaques typically seen in the alzheimer's disease brain, and this may reflect the accumulation of these biomarkers in the retina during the early stages of the disease, as seen in postmortem retinas of ad patients. 2024-02-10 2024-02-12 Not clear
Frederike C Oertel, Daniel Casillas, Yann Cobigo, Shivany Condor Montes, Hilary W Heuer, Makenna Chapman, Alexandra Beaudry-Richard, Henriette Reinsberg, Ahmed Abdelhak, Christian Cordano, Bradley F Boeve, Bradford C Dickerson, Murray Grossman, Edward Huey, David J Irwin, Irene Litvan, Alexander Pantelyat, M Carmela Tartaglia, Lawren Vandevrede, Adam Boxer, Ari J Gree. Scientific commentary on: "Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies". Acta neuropathologica. vol 147. issue 1. 2024-02-03. PMID:38308717. scientific commentary on: "phosphorylated tau in the retina correlates with tau pathology in the brain in alzheimer's disease and primary tauopathies". 2024-02-03 2024-02-06 Not clear
Laura Carrero, Desireé Antequera, Cristina Municio, Eva Carr. Circadian rhythm disruption and retinal dysfunction: a bidirectional link in Alzheimer's disease? Neural regeneration research. vol 19. issue 9. 2024-01-16. PMID:38227523. however, the mechanistic link between circadian dysfunction and the pathological changes affecting the retina in alzheimer's disease is not fully understood, although some studies point to the possibility that retinal dysfunction could be considered an early pathological process that directly modulates the circadian rhythm. 2024-01-16 2024-01-18 Not clear
Cristina Nuñez-Diaz, Emelie Andersson, Nina Schultz, Dovilė Pocevičiūtė, Oskar Hansson, K Peter R Nilsson, Malin Wennströ. The fluorescent ligand bTVBT2 reveals increased p-tau uptake by retinal microglia in Alzheimer's disease patients and App Alzheimer's research & therapy. vol 16. issue 1. 2024-01-03. PMID:38167557. the fluorescent ligand btvbt2 reveals increased p-tau uptake by retinal microglia in alzheimer's disease patients and app amyloid beta (aβ) deposits and hyperphosphorylated tau (p-tau) accumulation have been identified in the retina of alzheimer's disease (ad) patients and transgenic ad mice. 2024-01-03 2024-01-06 mouse
Varisha Zuhair, Hussain Sohail Rangwala, Zaib Un Nisa Mughal, Hareer Fatima, Areeba Tufail Shaikh, Abdullah Mussara. Viewing the Brain Through Retina: A New Avenue for Early Diagnosis of Alzheimer's Disease. Annals of neurosciences. vol 30. issue 4. 2023-12-01. PMID:38020399. viewing the brain through retina: a new avenue for early diagnosis of alzheimer's disease. 2023-12-01 2023-12-07 Not clear
Varisha Zuhair, Hussain Sohail Rangwala, Zaib Un Nisa Mughal, Hareer Fatima, Areeba Tufail Shaikh, Abdullah Mussara. Viewing the Brain Through Retina: A New Avenue for Early Diagnosis of Alzheimer's Disease. Annals of neurosciences. vol 30. issue 4. 2023-12-01. PMID:38020399. viewing the brain through retina: a new avenue for early diagnosis of alzheimer's disease. 2023-11-29 2023-12-07 Not clear
Louise Kelly, Christopher Brown, Daniel Michalik, Cheryl A Hawkes, Roxana Aldea, Nivedita Agarwal, Rami Salib, Aiman Alzetani, Douglas W Ethell, Scott E Counts, Mony de Leon, Silvia Fossati, Maya Koronyo-Hamaoui, Fabrizio Piazza, Steven A Rich, Frank J Wolters, Heather Snyder, Ozama Ismail, Fanny Elahi, Steven T Proulx, Ajay Verma, Hilary Wunderlich, Mareike Haack, Jean Cosme Dodart, Norman Mazer, Roxana O Carar. Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-11-07. PMID:37897797. cerebrovascular disease and the failure of elimination of amyloid-β from the brain and retina with age and alzheimer's disease: opportunities for therapy. 2023-11-07 2023-11-08 Not clear
Louise Kelly, Christopher Brown, Daniel Michalik, Cheryl A Hawkes, Roxana Aldea, Nivedita Agarwal, Rami Salib, Aiman Alzetani, Douglas W Ethell, Scott E Counts, Mony de Leon, Silvia Fossati, Maya Koronyo-Hamaoui, Fabrizio Piazza, Steven A Rich, Frank J Wolters, Heather Snyder, Ozama Ismail, Fanny Elahi, Steven T Proulx, Ajay Verma, Hilary Wunderlich, Mareike Haack, Jean Cosme Dodart, Norman Mazer, Roxana O Carar. Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-11-07. PMID:37897797. the overarching objectives of the clic group are to: (1) understand the age-related physiology changes that underlie impaired clearance of interstitial fluid (isf) and cerebrospinal fluid (csf) (clic); (2) understand the cellular and molecular mechanisms underlying intramural periarterial drainage (ipad) in the brain; (3) establish novel diagnostic tests for alzheimer's disease (ad), cerebral amyloid angiopathy (caa), retinal amyloid vasculopathy, amyloid-related imaging abnormalities (aria) of spontaneous and iatrogenic caa-related inflammation (caa-ri), and vasomotion; and (4) establish novel therapies that facilitate ipad to eliminate amyloid β (aβ) from the aging brain and retina, to prevent or reduce ad and caa pathology and aria side events associated with ad immunotherapy. 2023-11-07 2023-11-08 Not clear
Jessica Alber, Femke Bouwman, Jurre den Haan, Robert A Rissman, Lies De Groef, Maya Koronyo-Hamaoui, Imre Lengyel, Dietmar Rudolf Tha. Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-11-02. PMID:37917365. retina pathology as a target for biomarkers for alzheimer's disease: current status, ophthalmopathological background, challenges, and future directions. 2023-11-02 2023-11-08 Not clear
Jessica Alber, Femke Bouwman, Jurre den Haan, Robert A Rissman, Lies De Groef, Maya Koronyo-Hamaoui, Imre Lengyel, Dietmar Rudolf Tha. Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-11-02. PMID:37917365. there is emerging evidence that amyloid beta protein (aβ) and tau-related lesions in the retina are associated with alzheimer's disease (ad). 2023-11-02 2023-11-08 Not clear
Mattia Di Paolo, Francesca Corsi, Chiara Cerri, Silvia Bisti, Ilaria Piano, Claudia Gargin. A Window to the Brain: The Retina to Monitor the Progression and Efficacy of Saffron Repron Pharmaceuticals (Basel, Switzerland). vol 16. issue 9. 2023-09-28. PMID:37765115. a window to the brain: the retina to monitor the progression and efficacy of saffron repron a mechanism shared by most neurodegenerative diseases, like alzheimer's disease (ad) and parkinson's disease (pd), is neuroinflammation. 2023-09-28 2023-10-07 mouse
Shuntai Chen, Dian Zhang, Honggang Zheng, Tianyu Cao, Kun Xia, Mingwan Su, Qinggang Men. The association between retina thinning and hippocampal atrophy in Alzheimer's disease and mild cognitive impairment: a meta-analysis and systematic review. Frontiers in aging neuroscience. vol 15. 2023-09-08. PMID:37680540. the association between retina thinning and hippocampal atrophy in alzheimer's disease and mild cognitive impairment: a meta-analysis and systematic review. 2023-09-08 2023-10-07 human
Grzegorz Walkiewicz, Alicja Ronisz, Rita Van Ginderdeuren, Sophie Lemmens, Femke H Bouwman, Jeroen J M Hoozemans, Tjado H J Morrema, Annemieke J Rozemuller, Frederique J Hart de Ruyter, Lies De Groef, Ingeborg Stalmans, Dietmar Rudolf Tha. Primary retinal tauopathy: A tauopathy with a distinct molecular pattern. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-08-24. PMID:37615275. phosphorylated tau (p-tau) accumulation, a hallmark of alzheimer's disease (ad), can also be found in the retina. 2023-08-24 2023-09-07 Not clear
Valentina Latina, Anna Atlante, Francesca Malerba, Federico La Regina, Bijorn Omar Balzamino, Alessandra Micera, Annabella Pignataro, Egidio Stigliano, Sebastiano Cavallaro, Pietro Calissano, Giuseppina Amador. The Cleavage-Specific Tau 12A12mAb Exerts an Anti-Amyloidogenic Action by Modulating the Endocytic and Bioenergetic Pathways in Alzheimer's Disease Mouse Model. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298634. beyond deficits in hippocampal-dependent episodic memory, alzheimer's disease (ad) features sensory impairment in visual cognition consistent with extensive neuropathology in the retina. 2023-06-11 2023-08-14 mouse
Seyed Mostafa Hosseinpour Mashkani, David P Bishop, Newsha Raoufi-Rad, Paul A Adlard, Olga Shimoni, S Mojtaba Golza. Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer's Disease. Cells. vol 12. issue 8. 2023-05-16. PMID:37190053. distribution of copper, iron, and zinc in the retina, hippocampus, and cortex of the transgenic app/ps1 mouse model of alzheimer's disease. 2023-05-16 2023-08-14 mouse
Bingying Zhao, Yibing Yan, Xingqi Wu, Zhi Geng, Yue Wu, Guixian Xiao, Lu Wang, Shanshan Zhou, Ling Wei, Kai Wang, Rongfeng Lia. The correlation of retinal neurodegeneration and brain degeneration in patients with Alzheimer's disease using optical coherence tomography angiography and MRI. Frontiers in aging neuroscience. vol 15. 2023-05-01. PMID:37122375. pathological changes in alzheimer's disease can cause retina and optic nerve degeneration. 2023-05-01 2023-08-14 Not clear
Xiaoyu Ma, Zengmai Xie, Huan Wang, Zhongping Tian, Yanlong Bi, Yunxia Li, Li Zhan. A cross-sectional study of retinal vessel changes based on optical coherence tomography angiography in Alzheimer's disease and mild cognitive impairment. Frontiers in aging neuroscience. vol 15. 2023-04-28. PMID:37113575. the involvement of retina and its vasculature has been recently described in alzheimer's disease (ad). 2023-04-28 2023-08-14 Not clear
Suman Adhikari, Yuchuan Qiao, Maxwell Singer, Abhay Sagare, Xuejuan Jiang, Yonggang Shi, John M Ringman, Amir H Kashan. Retinotopic degeneration of the retina and optic tracts in autosomal dominant Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-04-27. PMID:37102308. retinotopic degeneration of the retina and optic tracts in autosomal dominant alzheimer's disease. 2023-04-27 2023-08-14 human
Heba Ahmed Gaber, Eman Mohamed Aly, Eman Saad Mohamed, Marwa Elfouly, Mona Salah Talaat, El-Sayed Mahmoud El-Saye. Prognosis of Biomarker of Alzheimer's Disease in the Function of the Retina and Secondary Molecular Structure Variation of the Retina and Brain. International journal of Alzheimer's disease. vol 2023. 2023-04-10. PMID:37035098. prognosis of biomarker of alzheimer's disease in the function of the retina and secondary molecular structure variation of the retina and brain. 2023-04-10 2023-08-14 rat
Ashleigh Barrett-Young, Wickliffe C Abraham, Carol Y Cheung, Jesse Gale, Sean Hogan, David Ireland, Ross Keenan, Annchen R Knodt, Tracy R Melzer, Terrie E Moffitt, Sandhya Ramrakha, Yih Chung Tham, Graham A Wilson, Tien Yin Wong, Ahmad R Hariri, Richie Poulto. Associations Between Thinner Retinal Neuronal Layers and Suboptimal Brain Structural Integrity in a Middle-Aged Cohort. Eye and brain. vol 15. 2023-03-20. PMID:36936476. the retina has potential as a biomarker of brain health and alzheimer's disease (ad) because it is the only part of the central nervous system which can be easily imaged and has advantages over brain imaging technologies. 2023-03-20 2023-08-14 Not clear