| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N A Kapay, N K Isaev, E V Stelmashook, O V Popova, D B Zorov, V G Skrebitsky, V P Skulache. In vivo injected mitochondria-targeted plastoquinone antioxidant SkQR1 prevents β-amyloid-induced decay of long-term potentiation in rat hippocampal slices. Biochemistry. Biokhimiia. vol 76. issue 12. 2012-04-19. PMID:22150282. |
these data demonstrate that skqr1 therapy is able to compensate the abeta-induced impairments of long-term synaptic plasticity in the hippocampus, which are the main cause of loss of memory and other cognitive functions associated with alzheimer's disease. |
2012-04-19 |
2023-08-12 |
rat |
| Vijay Antharam, Joanna F Collingwood, John-Paul Bullivant, Mark R Davidson, Saurav Chandra, Albina Mikhaylova, Mary E Finnegan, Christopher Batich, John R Forder, Jon Dobso. High field magnetic resonance microscopy of the human hippocampus in Alzheimer's disease: quantitative imaging and correlation with iron. NeuroImage. vol 59. issue 2. 2012-04-17. PMID:21867761. |
high field magnetic resonance microscopy of the human hippocampus in alzheimer's disease: quantitative imaging and correlation with iron. |
2012-04-17 |
2023-08-12 |
human |
| Vijay Antharam, Joanna F Collingwood, John-Paul Bullivant, Mark R Davidson, Saurav Chandra, Albina Mikhaylova, Mary E Finnegan, Christopher Batich, John R Forder, Jon Dobso. High field magnetic resonance microscopy of the human hippocampus in Alzheimer's disease: quantitative imaging and correlation with iron. NeuroImage. vol 59. issue 2. 2012-04-17. PMID:21867761. |
we report r(2) and r(2) in human hippocampus from five unfixed post-mortem alzheimer's disease (ad) and three age-matched control cases. |
2012-04-17 |
2023-08-12 |
human |
| Tomomi Kiyota, Kaitlin L Ingraham, Michael T Jacobsen, Huangui Xiong, Tsuneya Ikez. FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 49. 2012-04-13. PMID:22042871. |
fgf2 gene transfer restores hippocampal functions in mouse models of alzheimer's disease and has therapeutic implications for neurocognitive disorders. |
2012-04-13 |
2023-08-12 |
mouse |
| Yvonne S Davidson, Samantha Raby, Penelope G Foulds, Andrew Robinson, Jennifer C Thompson, Stephen Sikkink, Imran Yusuf, Hanan Amin, Daniel DuPlessis, Claire Troakes, Safa Al-Sarraj, Carolyn Sloan, Margaret M Esiri, Vee P Prasher, David Allsop, David Neary, Stuart M Pickering-Brown, Julie S Snowden, David M A Man. TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype. Acta neuropathologica. vol 122. issue 6. 2012-04-10. PMID:21968532. |
tdp-43 pathological changes in early onset familial and sporadic alzheimer's disease, late onset alzheimer's disease and down's syndrome: association with age, hippocampal sclerosis and clinical phenotype. |
2012-04-10 |
2023-08-12 |
Not clear |
| Yvonne S Davidson, Samantha Raby, Penelope G Foulds, Andrew Robinson, Jennifer C Thompson, Stephen Sikkink, Imran Yusuf, Hanan Amin, Daniel DuPlessis, Claire Troakes, Safa Al-Sarraj, Carolyn Sloan, Margaret M Esiri, Vee P Prasher, David Allsop, David Neary, Stuart M Pickering-Brown, Julie S Snowden, David M A Man. TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype. Acta neuropathologica. vol 122. issue 6. 2012-04-10. PMID:21968532. |
tdp-43 immunoreactive (tdp-43-ir) pathological changes were investigated in the temporal cortex and hippocampus of 11 patients with autosomal dominant familial forms of alzheimer's disease (fad), 169 patients with sporadic ad [85 with early onset disease (eoad) (i.e before 65 years of age), and 84 with late onset after this age (load)], 50 individuals with down's syndrome (ds) and 5 patients with primary hippocampal sclerosis (hs). |
2012-04-10 |
2023-08-12 |
Not clear |
| David J Irwin, Todd J Cohen, Murray Grossman, Steven E Arnold, Sharon X Xie, Virginia M-Y Lee, John Q Trojanowsk. Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366796. |
acetylated-tau pathology was compared with the sequential emergence of other tau modifications in the alzheimer's disease hippocampus using monoclonal antibodies to multiple well-characterized tau epitopes. |
2012-04-09 |
2023-08-12 |
Not clear |
| Igor Yakushev, Matthias Schreckenberger, Matthias J Müller, Ingrid Schermuly, Paul Cumming, Peter Stoeter, Alex Gerhard, Andreas Fellgiebe. Functional implications of hippocampal degeneration in early Alzheimer's disease: a combined DTI and PET study. European journal of nuclear medicine and molecular imaging. vol 38. issue 12. 2012-04-06. PMID:21792570. |
functional implications of hippocampal degeneration in early alzheimer's disease: a combined dti and pet study. |
2012-04-06 |
2023-08-12 |
human |
| Robert J Dawe, David A Bennett, Julie A Schneider, Konstantinos Arfanaki. Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study. PloS one. vol 6. issue 10. 2012-04-06. PMID:22043314. |
the volume of the hippocampus measured with structural magnetic resonance imaging (mri) is increasingly used as a biomarker for alzheimer's disease (ad). |
2012-04-06 |
2023-08-12 |
human |
| Robert J Dawe, David A Bennett, Julie A Schneider, Konstantinos Arfanaki. Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study. PloS one. vol 6. issue 10. 2012-04-06. PMID:22043314. |
first, to validate the information contained in postmortem mri data, we tested the hypothesis that postmortem hippocampal volume is smaller in subjects with clinically diagnosed alzheimer's disease compared to subjects with mild or no cognitive impairment, as observed in antemortem imaging studies. |
2012-04-06 |
2023-08-12 |
human |
| J J Rodríguez, H N Noristani, M Olabarria, J Fletcher, T D D Somerville, C Y Yeh, A Verkhratsk. Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease. Current Alzheimer research. vol 8. issue 7. 2012-04-04. PMID:21453244. |
voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of alzheimer's disease. |
2012-04-04 |
2023-08-12 |
mouse |
| Jaya R P Prasanthi, Tyler Larson, Jared Schommer, Othman Ghrib. Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. PloS one. vol 6. issue 10. 2012-03-26. PMID:22046282. |
silencing gadd153/chop gene expression protects against alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. |
2012-03-26 |
2023-08-12 |
rabbit |
| Robert D Dayton, David B Wang, Cooper D Cain, Lisa M Schrott, Julio J Ramirez, Michael A King, Ronald L Klei. Frontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus. Experimental neurology. vol 233. issue 2. 2012-03-26. PMID:22177996. |
the models could be of value for studying mechanisms of ftld and other diseases with tau and tdp-43 pathology in the hippocampus including alzheimer's disease, with relevance to early stage mild impairment. |
2012-03-26 |
2023-08-12 |
human |
| Pravat K Mandal, Manjari Tripathi, Sreedevi Suguna. Brain oxidative stress: detection and mapping of anti-oxidant marker 'Glutathione' in different brain regions of healthy male/female, MCI and Alzheimer patients using non-invasive magnetic resonance spectroscopy. Biochemical and biophysical research communications. vol 417. issue 1. 2012-03-22. PMID:22120629. |
we report in vivo detection of gsh non-invasively from various brain regions (frontal cortex, parietal cortex, hippocampus and cerebellum) in bilateral hemispheres of healthy male and female subjects and from bi-lateral frontal cortices in patients with mild cognitive impairment (mci) and alzheimer's disease (ad). |
2012-03-22 |
2023-08-12 |
human |
| Adelaide P Yiu, Asim J Rashid, Sheena A Jossely. Increasing CREB function in the CA1 region of dorsal hippocampus rescues the spatial memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 11. 2012-03-20. PMID:21734652. |
increasing creb function in the ca1 region of dorsal hippocampus rescues the spatial memory deficits in a mouse model of alzheimer's disease. |
2012-03-20 |
2023-08-12 |
mouse |
| Xi Li, Hai-Feng Yuan, Qian-Kun Quan, Jian-Jun Wang, Ning-Ning Wang, Ming L. Scavenging effect of Naoerkang on amyloid beta-peptide deposition in the hippocampus in a rat model of Alzheimer's disease. Chinese journal of integrative medicine. vol 17. issue 11. 2012-03-20. PMID:22057414. |
scavenging effect of naoerkang on amyloid beta-peptide deposition in the hippocampus in a rat model of alzheimer's disease. |
2012-03-20 |
2023-08-12 |
rat |
| Xi Li, Hai-Feng Yuan, Qian-Kun Quan, Jian-Jun Wang, Ning-Ning Wang, Ming L. Scavenging effect of Naoerkang on amyloid beta-peptide deposition in the hippocampus in a rat model of Alzheimer's disease. Chinese journal of integrative medicine. vol 17. issue 11. 2012-03-20. PMID:22057414. |
to observe the effect of a chinese medicine compound, naoerkang (nek), on amyloid-beta peptide (1-42; aβ(1-42)) and matrix metalloproteinase-9 (mmp-9) expressions in the hippocampus of alzheimer's disease (ad) model rats. |
2012-03-20 |
2023-08-12 |
rat |
| Changsheng Wang, Glenn T Stebbins, David A Medina, Raj C Shah, Roland Bammer, Michael E Moseley, Leyla deToledo-Morrel. Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease. Neurobiology of aging. vol 33. issue 1. 2012-03-13. PMID:20359781. |
in addition to atrophy of mesial temporal lobe structures critical for memory function, white matter projections to the hippocampus may be compromised in individuals with mild alzheimer's disease (ad), thereby compounding the memory difficulty. |
2012-03-13 |
2023-08-12 |
Not clear |
| Nicole L Bjorklund, V-M Sadagoparamanujam, Giulio Taglialatel. Selective, quantitative measurement of releasable synaptic zinc in human autopsy hippocampal brain tissue from Alzheimer's disease patients. Journal of neuroscience methods. vol 203. issue 1. 2012-03-08. PMID:21945000. |
selective, quantitative measurement of releasable synaptic zinc in human autopsy hippocampal brain tissue from alzheimer's disease patients. |
2012-03-08 |
2023-08-12 |
human |
| Yong-chang Diwu, Jin-zhou Tian, Jing Sh. Effects of Chinese herbal medicine Yinsiwei compound on spatial learning and memory ability and the ultrastructure of hippocampal neurons in a rat model of sporadic Alzheimer disease. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. vol 9. issue 2. 2012-03-07. PMID:21288458. |
effects of chinese herbal medicine yinsiwei compound on spatial learning and memory ability and the ultrastructure of hippocampal neurons in a rat model of sporadic alzheimer disease. |
2012-03-07 |
2023-08-12 |
rat |