| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. |
increased hippocampal blood flow in sedentary older adults at genetic risk for alzheimer's disease. |
2015-09-18 |
2023-08-12 |
Not clear |
| Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. |
resting cerebral blood flow (cbf) decreases with age; however regulatory increases in hippocampal cbf have been associated with genetic risk (apolipoprotein e [apoe] ε4 carriers) for alzheimer's disease (ad). |
2015-09-18 |
2023-08-12 |
Not clear |
| Jiu Chen, Zhijun Zhang, Shijiang L. Can multi-modal neuroimaging evidence from hippocampus provide biomarkers for the progression of amnestic mild cognitive impairment? Neuroscience bulletin. vol 31. issue 1. 2015-09-18. PMID:25595368. |
impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment (amci) to alzheimer's disease (ad). |
2015-09-18 |
2023-08-13 |
Not clear |
| Federico Scala, Salvatore Fusco, Cristian Ripoli, Roberto Piacentini, Domenica Donatella Li Puma, Matteo Spinelli, Fernanda Laezza, Claudio Grassi, Marcello D'Ascenz. Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3. Neurobiology of aging. vol 36. issue 2. 2015-09-17. PMID:25541422. |
in acute hippocampal slices derived from an adult triple-transgenic alzheimer's mouse model, characterized by endogenous intracellular accumulation of aβ42, ca1 pyramidal neurons exhibit hyperexcitability accompanied by increased phosphorylation of kv4.2 at ser-616. |
2015-09-17 |
2023-08-13 |
mouse |
| Robin de Flores, Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Florence Mézenge, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Effects of age and Alzheimer's disease on hippocampal subfields: comparison between manual and FreeSurfer volumetry. Human brain mapping. vol 36. issue 2. 2015-09-16. PMID:25231681. |
effects of age and alzheimer's disease on hippocampal subfields: comparison between manual and freesurfer volumetry. |
2015-09-16 |
2023-08-13 |
Not clear |
| Robin de Flores, Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Florence Mézenge, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Effects of age and Alzheimer's disease on hippocampal subfields: comparison between manual and FreeSurfer volumetry. Human brain mapping. vol 36. issue 2. 2015-09-16. PMID:25231681. |
hippocampal subfields were segmented in 133 individuals including 98 cognitively normal controls aged 19-84 years, 17 mild cognitive impairment and 18 alzheimer's disease (ad) patients using both methods. |
2015-09-16 |
2023-08-13 |
Not clear |
| Ya-min Liu, Zong-yang Li, Han Hu, Shu-ping Xu, Qi Chang, Yong-hong Liao, Rui-le Pan, Xin-min Li. Tenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25-35 peptides in vitro and in vivo. Pharmacology, biochemistry, and behavior. vol 128. 2015-09-16. PMID:25444865. |
alzheimer's disease (ad) is associated with damage to hippocampal neurons and declines in cognitive functions. |
2015-09-16 |
2023-08-13 |
mouse |
| F Clavaguera, J Hench, M Goedert, M Tolna. Invited review: Prion-like transmission and spreading of tau pathology. Neuropathology and applied neurobiology. vol 41. issue 1. 2015-09-15. PMID:25399729. |
in the most prevalent tauopathy, alzheimer's disease, tau pathology progresses in a stereotypical manner with the first lesions appearing in the locus coeruleus and the entorhinal cortex from where they appear to spread to the hippocampus and neocortex. |
2015-09-15 |
2023-08-13 |
Not clear |
| Tomoko Kato, Yoshihiro Konishi, Shun Shimohama, Thomas G Beach, Hiroyasu Akatsu, Ikuo Tooyam. Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients. Neuroscience letters. vol 591. 2015-09-15. PMID:25676811. |
in situ hybridization studies demonstrated that α1-chimaerin was expressed by neurons in the neo-cortex of the temporal lobe and the hippocampus of both controls and alzheimer's disease cases, with the signal intensity dramatically decreased in patients with alzheimer's disease. |
2015-09-15 |
2023-08-13 |
human |
| Yen Ying Lim, Robert H Pietrzak, Pierrick Bourgeat, David Ames, Kathryn A Ellis, Alan Rembach, Karra Harrington, Olivier Salvado, Ralph N Martins, Peter J Snyder, Colin L Masters, Christopher C Rowe, Victor L Villemagne, Paul Maruf. Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 30. issue 1. 2015-09-11. PMID:25467942. |
analysis of interrelationships between these alzheimer's disease markers in aβ+ cns and mcis indicated that rate of aβ accumulation was associated with rate of hippocampal atrophy (β = -0.05, p = .037), which was in turn associated independently with rate of decline in memory (β = -0.03, p = .032). |
2015-09-11 |
2023-08-13 |
Not clear |
| Shu-e Cao, Jianmin Tian, Shengyang Chen, Xiaoran Zhang, Yongqiang Zhan. Role of miR-34c in ketamine-induced neurotoxicity in neonatal mice hippocampus. Cell biology international. vol 39. issue 2. 2015-09-10. PMID:25052764. |
we have used an in vivo neonatal mouse model to induce ketamine-related neurotoxicity in the hippocampus, and found that mir-34c, a microrna associated with pathogenesis of alzheimer's disease, was significantly upregulated during ketamine-induced hippocampal neurodegeneration. |
2015-09-10 |
2023-08-13 |
mouse |
| Per Suppa, Ulrich Anker, Lothar Spies, Irene Bopp, Brigitte Rüegger-Frey, Richard Klaghofer, Carola Gocke, Harald Hampel, Sacha Beck, Ralph Bucher. Fully automated atlas-based hippocampal volumetry for detection of Alzheimer's disease in a memory clinic setting. Journal of Alzheimer's disease : JAD. vol 44. issue 1. 2015-09-10. PMID:25201782. |
fully automated atlas-based hippocampal volumetry for detection of alzheimer's disease in a memory clinic setting. |
2015-09-10 |
2023-08-13 |
Not clear |
| Per Suppa, Ulrich Anker, Lothar Spies, Irene Bopp, Brigitte Rüegger-Frey, Richard Klaghofer, Carola Gocke, Harald Hampel, Sacha Beck, Ralph Bucher. Fully automated atlas-based hippocampal volumetry for detection of Alzheimer's disease in a memory clinic setting. Journal of Alzheimer's disease : JAD. vol 44. issue 1. 2015-09-10. PMID:25201782. |
hippocampal volume is a promising biomarker to enhance the accuracy of the diagnosis of dementia due to alzheimer's disease (ad). |
2015-09-10 |
2023-08-13 |
Not clear |
| Wenjia Zhang, Xue Wang, Zijian Zhou, You Qiong L. A quantitative magnetic resonance study of the hippocampus and the temporal horn of the lateral ventricle in healthy subjects. The Journal of craniofacial surgery. vol 24. issue 3. 2015-09-09. PMID:23714936. |
hippocampal volume has been measured and used to separate the people who have alzheimer disease, stress-related psychiatric disorders such as posttraumatic stress disorder, borderline personality disorder, and schizophrenia from normal people. |
2015-09-09 |
2023-08-12 |
human |
| Yuxin Yi, Shixing Wu, Maosheng Ye, Yi Zeng, Ping Zhang, Yiqun Xi. [Effect of Aβ1-42 injection on hippocampus cells in rats and protective role of polygona-polysaccharose for Alzheimer's disease]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 39. issue 4. 2015-09-08. PMID:24820272. |
[effect of aβ1-42 injection on hippocampus cells in rats and protective role of polygona-polysaccharose for alzheimer's disease]. |
2015-09-08 |
2023-08-13 |
rat |
| Edward D Levin, Brandon J Hall, Amir H Rezvan. Heterogeneity across brain regions and neurotransmitter interactions with nicotinic effects on memory function. Current topics in behavioral neurosciences. vol 23. 2015-09-08. PMID:25655888. |
alzheimer's disease results in a dramatic decrease in hippocampal nicotinic receptor density, affecting α4β2 receptor expression most prominently. |
2015-09-08 |
2023-08-13 |
rat |
| Ashok K Shett. Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: can early neural stem cell grafting intervention provide protection? Epilepsy & behavior : E&B. vol 38. 2015-09-03. PMID:24433836. |
damage to the hippocampus can occur through many causes including head trauma, ischemia, stroke, status epilepticus, and alzheimer's disease. |
2015-09-03 |
2023-08-12 |
Not clear |
| Ashok K Shett. Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: can early neural stem cell grafting intervention provide protection? Epilepsy & behavior : E&B. vol 38. 2015-09-03. PMID:24433836. |
this review presents advancements made in nsc grafting therapy for treating hippocampal injury in animal models of excitotoxic injury, traumatic brain injury, alzheimer's disease, and status epilepticus; potential mechanisms of functional recovery mediated by nsc grafts placed early after hippocampal injury; and issues that need to be resolved prior to considering clinical application of nsc grafting for hippocampal injury. |
2015-09-03 |
2023-08-12 |
Not clear |
| Marjan Shariatpanahi, Fariba Khodagholi, Ghorbangol Ashabi, Azar Aghazadeh Khasraghi, Leila Azimi, Mohammad Abdollahi, Mohammad Hossein Ghahremani, Seyed Nasser Ostad, Farshid Noorbakhsh, Mohammad Sharifzade. Ameliorating of Memory Impairment and Apoptosis in Amyloid β-Injected Rats Via Inhibition of Nitric Oxide Synthase: Possible Participation of Autophagy. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 3. 2015-09-02. PMID:26330869. |
it has been proposed that appearance of amyloid beta (aβ) in hippocampus is one of the characteristic features of alzheimer's disease (ad). |
2015-09-02 |
2023-08-13 |
rat |
| Ephraim F Trakhtenberg, Melina I Morkin, Karan H Patel, Stephanie G Fernandez, Alan Sang, Peter Shaw, Xiongfei Liu, Yan Wang, Gregory M Mlacker, Han Gao, Dmitry Velmeshev, Susan M Dombrowski, Michael P Vitek, Jeffrey L Goldber. The N-terminal Set-β Protein Isoform Induces Neuronal Death. The Journal of biological chemistry. vol 290. issue 21. 2015-09-01. PMID:25833944. |
the expression and subcellular localization of set-β are altered in alzheimer disease, cleavage of set-β leads to neuronal death after stroke, and the full-length set-β regulates retinal ganglion cell (rgc) and hippocampal neuron axon growth and regeneration in a subcellular localization-dependent manner. |
2015-09-01 |
2023-08-13 |
Not clear |