| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fehmida Bibi, Muhammad Yasir, Sayed S Sohrab, Esam I Azhar, Mohammed H Al-Qahtani, Adel M Abuzenadah, Mohammad A Kamal, Muhammad I Nasee. Link between chronic bacterial inflammation and Alzheimer disease. CNS & neurological disorders drug targets. vol 13. issue 7. 2015-07-13. PMID:25230225. |
alzheimer's disease (ad) is a degenerative disease of brain that is associated with dementia, brain atrophy, accumulation of hyperphosphorylated tau protein and amyloid-beta peptide in hippocampus and cortex region of the brain. |
2015-07-13 |
2023-08-13 |
Not clear |
| Fang Yu, Ulf G Bronas, Suma Konety, Nathaniel W Nelson, Maurice Dysken, Clifford Jack, Jean F Wyman, David Vock, Glenn Smit. Effects of aerobic exercise on cognition and hippocampal volume in Alzheimer's disease: study protocol of a randomized controlled trial (The FIT-AD trial). Trials. vol 15. 2015-07-09. PMID:25304364. |
effects of aerobic exercise on cognition and hippocampal volume in alzheimer's disease: study protocol of a randomized controlled trial (the fit-ad trial). |
2015-07-09 |
2023-08-13 |
Not clear |
| X Chen, J Hu, L Jiang, S Xu, B Zheng, C Wang, J Zhang, X Wei, L Chang, Q Wan. Brilliant Blue G improves cognition in an animal model of Alzheimer's disease and inhibits amyloid-β-induced loss of filopodia and dendrite spines in hippocampal neurons. Neuroscience. vol 279. 2015-07-08. PMID:25193238. |
brilliant blue g improves cognition in an animal model of alzheimer's disease and inhibits amyloid-β-induced loss of filopodia and dendrite spines in hippocampal neurons. |
2015-07-08 |
2023-08-13 |
mouse |
| Amina Chaalal, Roseline Poirier, David Blum, Brigitte Gillet, Pascale Le Blanc, Marie Basquin, Luc Buée, Serge Laroche, Valérie Enderli. PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments. Hippocampus. vol 24. issue 11. 2015-07-07. PMID:24978200. |
ptu-induced hypothyroidism in rats leads to several early neuropathological signs of alzheimer's disease in the hippocampus and spatial memory impairments. |
2015-07-07 |
2023-08-13 |
rat |
| Guangyu Chen, B Douglas Ward, Gang Chen, Shi-Jiang L. Decreased effective connectivity from cortices to the right parahippocampal gyrus in Alzheimer's disease subjects. Brain connectivity. vol 4. issue 9. 2015-07-06. PMID:25132215. |
the purpose of this study was to detect effective connectivity (ec) changes in the default mode network and hippocampus network in 20 patients with alzheimer's disease (ad) and 20 cognitively normal (cn) subjects, using multivariate granger causality. |
2015-07-06 |
2023-08-13 |
human |
| Shunjiang Xu, Rui Zhang, Jingya Niu, Dongsheng Cui, Bing Xie, Binggui Zhang, Kang Lu, Wenjun Yu, Xueyi Wang, Qingfu Zhan. Oxidative stress mediated-alterations of the microRNA expression profile in mouse hippocampal neurons. International journal of molecular sciences. vol 13. issue 12. 2015-07-03. PMID:23443129. |
these results demonstrated that oxidative stress alters the mirna expression profile of hippocampal neurons, and the deregulated mirnas might play a potential role in the pathogenesis of neurodegenerative diseases, such as alzheimer's disease (ad). |
2015-07-03 |
2023-08-12 |
mouse |
| K An, J H Jung, A Y Jeong, H G Kim, S Y Jung, K Lee, H J Kim, S-J Kim, T-Y Jeong, Y Son, H-S Kim, J-H Ki. Neuritin can normalize neural deficits of Alzheimer's disease. Cell death & disease. vol 5. 2015-07-02. PMID:25393479. |
reductions in hippocampal neurite complexity and synaptic plasticity are believed to contribute to the progressive impairment in episodic memory and the mild cognitive decline that occur particularly in the early stages of alzheimer's disease (ad). |
2015-07-02 |
2023-08-13 |
mouse |
| Mina Eftekharzadeh, Maliheh Nobakht, Akram Alizadeh, Mansooreh Soleimani, Mahmood Hajghasem, Bahareh Kordestani Shargh, Nushin Karkuki Osguei, Babak Behnam, Ali Samadikuchaksarae. The effect of intrathecal delivery of bone marrow stromal cells on hippocampal neurons in rat model of Alzheimer's disease. Iranian journal of basic medical sciences. vol 18. issue 5. 2015-06-30. PMID:26124940. |
the effect of intrathecal delivery of bone marrow stromal cells on hippocampal neurons in rat model of alzheimer's disease. |
2015-06-30 |
2023-08-13 |
rat |
| Martin Vyhnalek, Tomas Nikolai, Ross Andel, Zuzana Nedelska, Eva Rubínová, Hana Marková, Jan Laczó, Ondrej Bezdicek, Katerina Sheardova, Jakub Hor. Neuropsychological correlates of hippocampal atrophy in memory testing in nondemented older adults. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:24670399. |
cognitive deficits in older adults attributable to alzheimer's disease (ad) pathology are featured early on by hippocampal impairment. |
2015-06-29 |
2023-08-12 |
Not clear |
| Costas A Anastasiou, Mary Yannakoulia, Nikolaos Scarmea. Vitamin D and cognition: an update of the current evidence. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:24820017. |
on the other hand, vitamin d has been found to be protective against biological processes associated with alzheimer's disease and cognition, including amyloid-β deposition, inflammation, calcium homeostasis, and corticosteroid-induced perturbations in cortical areas and the hippocampus. |
2015-06-29 |
2023-08-13 |
human |
| Ze Wan. Characterizing early Alzheimer's disease and disease progression using hippocampal volume and arterial spin labeling perfusion MRI. Journal of Alzheimer's disease : JAD. vol 42 Suppl 4. 2015-06-29. PMID:25182742. |
characterizing early alzheimer's disease and disease progression using hippocampal volume and arterial spin labeling perfusion mri. |
2015-06-29 |
2023-08-13 |
Not clear |
| Ya-Ting Chang, Chi-Wei Huang, Yen-Hsiang Chang, Nai-Ching Chen, Kun-Ju Lin, Tzu-Chen Yan, Wen-Neng Chang, Sz-Fan Chen, Chun-Chung Lui, Pin-Hsuan Lin, Chiung-Chih Chan. Amyloid burden in the hippocampus and default mode network: relationships with gray matter volume and cognitive performance in mild stage Alzheimer disease. Medicine. vol 94. issue 16. 2015-06-26. PMID:25906109. |
amyloid burden in the hippocampus and default mode network: relationships with gray matter volume and cognitive performance in mild stage alzheimer disease. |
2015-06-26 |
2023-08-13 |
Not clear |
| Maria Pascual-Lucas, Silvia Viana da Silva, Marianna Di Scala, Carolina Garcia-Barroso, Gloria González-Aseguinolaza, Christophe Mulle, Cristina M Alberini, Mar Cuadrado-Tejedor, Ana Garcia-Ost. Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice. EMBO molecular medicine. vol 6. issue 10. 2015-06-22. PMID:25100745. |
furthermore, we report that igf2 expression decreases in the hippocampus of patients with alzheimer's disease, and this leads us to hypothesize that increased igf2 levels may be beneficial for treating the disease. |
2015-06-22 |
2023-08-13 |
mouse |
| Julie Davies, Elena Zachariades, Karly-Rai Rogers-Broadway, Emmanouil Karteri. Elucidating the role of DEPTOR in Alzheimer's disease. International journal of molecular medicine. vol 34. issue 5. 2015-06-17. PMID:25119265. |
it has also been implicated in alzheimer's disease (ad) with neuronal cells and hippocampal slices of ad transgenic mice experiencing dysregulated mtor and synaptic plasticity in response to treatment with the toxic amyloid β (aβ(1-42)) peptide, which has been implicated in ad. |
2015-06-17 |
2023-08-13 |
mouse |
| Mark L Cohen, Chae Kim, Tracy Haldiman, Mohamed ElHag, Prachi Mehndiratta, Termsarasab Pichet, Frances Lissemore, Michelle Shea, Yvonne Cohen, Wei Chen, Janis Blevins, Brian S Appleby, Krystyna Surewicz, Witold K Surewicz, Martha Sajatovic, Curtis Tatsuoka, Shulin Zhang, Ping Mayo, Mariusz Butkiewicz, Jonathan L Haines, Alan J Lerner, Jiri G Safa. Rapidly progressive Alzheimer's disease features distinct structures of amyloid-β. Brain : a journal of neurology. vol 138. issue Pt 4. 2015-06-16. PMID:25688081. |
using novel biophysical methods, we analysed levels, particle size, and conformational characteristics of amyloid-β in the posterior cingulate cortex, hippocampus and cerebellum of 48 cases of alzheimer's disease with distinctly different disease durations, and correlated the data with apoe gene polymorphism. |
2015-06-16 |
2023-08-13 |
Not clear |
| Motoyasu Honma, Takeshi Kuroda, Akinori Futamura, Azusa Sugimoto, Mitsuru Kawamur. [Mental time dysfunction in Parkinson's and Alzheimer's diseases]. Brain and nerve = Shinkei kenkyu no shinpo. vol 67. issue 3. 2015-06-16. PMID:25846444. |
it is possible that the dysfunction of mental time in parkinson's disease is caused by the abnormal striatum acting as a pacemaker, while that in alzheimer's disease is caused by abnormal hippocampal memory. |
2015-06-16 |
2023-08-13 |
Not clear |
| Sylvia E Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen D Ginsberg, Milos D Ikonomovic, Elliott J Mufso. Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology. Journal of neuropathology and experimental neurology. vol 74. issue 4. 2015-06-15. PMID:25756588. |
endosomal-lysosomal and autophagic dysregulation occurs in the hippocampus in prodromal alzheimer disease (ad), but its relationship with β-amyloid (aβ) and tau pathology remains unclear. |
2015-06-15 |
2023-08-13 |
Not clear |
| K Kinugawa, V H Nguyen-Michel, J Marian. [Obstructive sleep apnea syndrome: a cause of cognitive disorders in the elderly?]. La Revue de medecine interne. vol 35. issue 10. 2015-06-08. PMID:24630586. |
the obstructive sleep apnea syndrome with cognitive impairment shares some features with alzheimer's disease, involving genetic predisposition apoe4, hippocampus and synaptic plasticity abnormalities. |
2015-06-08 |
2023-08-12 |
human |
| Melissa E Murray, Ashley Cannon, Neill R Graff-Radford, Amanda M Liesinger, Nicola J Rutherford, Owen A Ross, Ranjan Duara, Minerva M Carrasquillo, Rosa Rademakers, Dennis W Dickso. Differential clinicopathologic and genetic features of late-onset amnestic dementias. Acta neuropathologica. vol 128. issue 3. 2015-06-08. PMID:24899141. |
hippocampal sclerosis of the elderly (hpscl) and alzheimer's disease (ad), especially the limbic-predominant subtype (lp-ad), are amnestic syndromes that can be difficult to distinguish. |
2015-06-08 |
2023-08-13 |
Not clear |
| Wenjun Li, Piero G Antuono, Chunming Xie, Gang Chen, Jennifer L Jones, B Douglas Ward, Suraj P Singh, Malgorzata B Franczak, Joseph S Goveas, Shi-Jiang L. Aberrant functional connectivity in Papez circuit correlates with memory performance in cognitively intact middle-aged APOE4 carriers. Cortex; a journal devoted to the study of the nervous system and behavior. vol 57. 2015-06-04. PMID:24905971. |
the main objective of this study is to detect the early changes in resting-state papez circuit functional connectivity using the hippocampus as the seed, and to determine the associations between altered functional connectivity (fc) and the episodic memory performance in cognitively intact middle-aged apolipoprotein e4 (apoe4) carriers who are at risk of alzheimer's disease (ad). |
2015-06-04 |
2023-08-13 |
human |